Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-β-stimulated collagen production by cardiac fibroblasts

Cardiovascular Research

Volumn 82, Issue 2, 2009, Pages 303-312

  Gellings Lowe, Nicole ^a   Swaney, James S ^a,b   Moreno, Kelli M ^b   Sabbadini, Roger A ^a,b  

^a SAN DIEGO STATE UNIVERSITY   (United States)

^b Lpath Inc   (United States)

Author keywords

Smooth muscle actin; Cardiac fibroblast; Collagen; Fibrosis; S1P; Sphingosine kinase; TGF

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; COLLAGEN; MONOCLONAL ANTIBODY; RHO KINASE; SMALL INTERFERING RNA; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE MONOCLONAL ANTIBODY; SPHINGOSINE KINASE; SPHINGOSINE KINASE 1; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; AUTOCRINE EFFECT; BLAST TRANSFORMATION; CONTROLLED STUDY; FIBROBLAST; HEART; MALE; MOUSE; NONHUMAN; PARACRINE SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL DIFFERENTIATION; CELLS, CULTURED; COLLAGEN; ENZYME INHIBITORS; FIBROBLASTS; LYMPHOTOXIN-ALPHA; LYSOPHOSPHOLIPIDS; MALE; MICE; MICE, INBRED C57BL; MYOCARDIUM; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); RHO-ASSOCIATED KINASES; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SPHINGOSINE;

EID: 67449124297     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvp056     Document Type: Article

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