-
1
-
-
84869049715
-
Metabolic phenotyping in clinical and surgical environments
-
Nicholson JK, Holmes E, Kinross JM, Darzi AW, Takats Z, Lindon JC. Metabolic phenotyping in clinical and surgical environments. Nature 2012;491:384-92.
-
(2012)
Nature
, vol.491
, pp. 384-392
-
-
Nicholson, J.K.1
Holmes, E.2
Kinross, J.M.3
Darzi, A.W.4
Takats, Z.5
Lindon, J.C.6
-
2
-
-
43749087841
-
Human metabolic phenotype diversity and its association with diet and blood pressure
-
Holmes E, Loo RL, Stamler J, Bictash M, Yap IK, Chan Q, et al. Human metabolic phenotype diversity and its association with diet and blood pressure. Nature 2008;453:396-400.
-
(2008)
Nature
, vol.453
, pp. 396-400
-
-
Holmes, E.1
Loo, R.L.2
Stamler, J.3
Bictash, M.4
Yap, I.K.5
Chan, Q.6
-
3
-
-
84904876893
-
Emerging mass spectrometry techniques for the direct analysis of microbial colonies
-
Fang J, Dorrestein PC. Emerging mass spectrometry techniques for the direct analysis of microbial colonies. Curr Opin Microbiol 2015;19:120-9.
-
(2015)
Curr Opin Microbiol
, vol.19
, pp. 120-129
-
-
Fang, J.1
Dorrestein, P.C.2
-
4
-
-
84926322789
-
Exometabolomics and MSI: Deconstructing how cells interact to transform their small molecule environment
-
Silva LP, Northern TR. Exometabolomics and MSI: deconstructing how cells interact to transform their small molecule environment. Curr Opin Biotechnol 2015;34:209-16.
-
(2015)
Curr Opin Biotechnol
, vol.34
, pp. 209-216
-
-
Silva, L.P.1
Northern, T.R.2
-
5
-
-
7444253428
-
Systems biology and new technologies enable predictive and preventative medicine
-
Hood L, Heath JR, Phelps ME, Lin B. Systems biology and new technologies enable predictive and preventative medicine. Science 2004;306:640-3.
-
(2004)
Science
, vol.306
, pp. 640-643
-
-
Hood, L.1
Heath, J.R.2
Phelps, M.E.3
Lin, B.4
-
6
-
-
84906861310
-
High-throughput discovery metabolomics
-
Fuhrer T, Zamboni N. High-throughput discovery metabolomics. Curr Opin Biotechnol 2015;31:73-8.
-
(2015)
Curr Opin Biotechnol
, vol.31
, pp. 73-78
-
-
Fuhrer, T.1
Zamboni, N.2
-
7
-
-
84858790233
-
Innovation: Metabolomics: The apogee of the omics trilogy
-
Patti GJ, Yanes O, Siuzdak G. Innovation: metabolomics: the apogee of the omics trilogy. Nat Rev Mol Cell Biol 2012;13:263-9.
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 263-269
-
-
Patti, G.J.1
Yanes, O.2
Siuzdak, G.3
-
8
-
-
84961288989
-
Ion mobility-mass spectrometry: Time dispersive instrumentation
-
May JC, McLean JA. Ion mobility-mass spectrometry: time dispersive instrumentation. Anal Chem 2015;87:1422-36.
-
(2015)
Anal Chem
, vol.87
, pp. 1422-1436
-
-
May, J.C.1
McLean, J.A.2
-
9
-
-
84910017199
-
Ion mobility-mass spectrometry strategies for untargeted systems, synthetic, and chemical biology
-
May JC, Goodwin CR, McLean JA. Ion mobility-mass spectrometry strategies for untargeted systems, synthetic, and chemical biology. Curr Opin Biotechnol 2015;31:117-21.
-
(2015)
Curr Opin Biotechnol
, vol.31
, pp. 117-121
-
-
May, J.C.1
Goodwin, C.R.2
McLean, J.A.3
-
10
-
-
5444250387
-
Applications of a travelling wave-based radio-frequency-only stacked ring ion guide
-
Giles K, Pringle SD, Worthington KR, Little D, Wildgoose JL, Bateman RH. Applications of a travelling wave-based radio-frequency-only stacked ring ion guide. Rapid Commun Mass Spectrom 2004;18:2401-14.
-
(2004)
Rapid Commun Mass Spectrom
, vol.18
, pp. 2401-2414
-
-
Giles, K.1
Pringle, S.D.2
Worthington, K.R.3
Little, D.4
Wildgoose, J.L.5
Bateman, R.H.6
-
11
-
-
84894273930
-
Conformational ordering of biomolecules in the gas-phase: Nitrogen collision cross-sections measured on a prototype high resolution drift tube ion mobility-mass spectrometer
-
May JC, Goodwin CR, Lareau NM, Leaptrot KL, Morris CB, Kurulugama RT, et al. Conformational ordering of biomolecules in the gas-phase: nitrogen collision cross-sections measured on a prototype high resolution drift tube ion mobility-mass spectrometer. Anal Chem 2014;86:2107-16.
-
(2014)
Anal Chem
, vol.86
, pp. 2107-2116
-
-
May, J.C.1
Goodwin, C.R.2
Lareau, N.M.3
Leaptrot, K.L.4
Morris, C.B.5
Kurulugama, R.T.6
-
12
-
-
43949111970
-
Biomolecular structural separations by ion mobility-mass spectrometry
-
Fenn LS, McLean JA. Biomolecular structural separations by ion mobility-mass spectrometry. Anal Bioanal Chem 2008;391:905-9.
-
(2008)
Anal Bioanal Chem
, vol.391
, pp. 905-909
-
-
Fenn, L.S.1
McLean, J.A.2
-
13
-
-
65049088697
-
Characterizing ion mobility-mass spectrometry conformation space for the analysis of complex biological samples
-
Fenn LS, Kliman M, Mahsut A, Zhao SR, McLean JA. Characterizing ion mobility-mass spectrometry conformation space for the analysis of complex biological samples. Anal Bioanal Chem 2009;394:235-44.
-
(2009)
Anal Bioanal Chem
, vol.394
, pp. 235-244
-
-
Fenn, L.S.1
Kliman, M.2
Mahsut, A.3
Zhao, S.R.4
McLean, J.A.5
-
14
-
-
80255140521
-
Lipid analysis and lipidomics by structurally selective ion mobility-mass spectrometry
-
Kliman M, May JC, McLean JA. Lipid analysis and lipidomics by structurally selective ion mobility-mass spectrometry. Biochim Biophys Acta 2011;1811:935-45.
-
(2011)
Biochim Biophys Acta
, vol.1811
, pp. 935-945
-
-
Kliman, M.1
May, J.C.2
McLean, J.A.3
-
15
-
-
80052669512
-
Localization of fatty acyl and double bond positions in phosphatidylcholines using a dual stage CID fragmentation coupled with ion mobility mass spectrometry
-
Castro-Perez J, Roddy TP, Nibbering NM, Shah V, McLaren DG, Previs S, et al. Localization of fatty acyl and double bond positions in phosphatidylcholines using a dual stage CID fragmentation coupled with ion mobility mass spectrometry. J Am Soc Mass Spectrom 2011;22:1552-67.
-
(2011)
J Am Soc Mass Spectrom
, vol.22
, pp. 1552-1567
-
-
Castro-Perez, J.1
Roddy, T.P.2
Nibbering, N.M.3
Shah, V.4
McLaren, D.G.5
Previs, S.6
-
16
-
-
78649980497
-
Lipidomics: New tools and applications
-
Wenk MR. Lipidomics: new tools and applications. Cell 2010;143:888-95.
-
(2010)
Cell
, vol.143
, pp. 888-895
-
-
Wenk, M.R.1
-
17
-
-
84890906297
-
Discrimination of epimeric glycans and glycopeptides using IM-MS and its potential for carbohydrate sequencing
-
Both P, Green AP, Gray CJ, Sardzík R, Voglmeir J, Fontana C, et al. Discrimination of epimeric glycans and glycopeptides using IM-MS and its potential for carbohydrate sequencing. Nat Chem 2014;6:65-74.
-
(2014)
Nat Chem
, vol.6
, pp. 65-74
-
-
Both, P.1
Green, A.P.2
Gray, C.J.3
Sardzík, R.4
Voglmeir, J.5
Fontana, C.6
-
18
-
-
79955753022
-
Ion mobility mass spectrometry for extracting spectra of N-glycans directly from incubation mixtures following glycan release: Application to glycans from engineered glycoforms of intact, folded HIV gp120
-
Harvey DJ, Sobott F, Crispin M, Wrobel A, Bonomelli C, Vasiljevic S, et al. Ion mobility mass spectrometry for extracting spectra of N-glycans directly from incubation mixtures following glycan release: application to glycans from engineered glycoforms of intact, folded HIV gp120. J Am Soc Mass Spectrom 2010;22:568-81.
-
(2010)
J Am Soc Mass Spectrom
, vol.22
, pp. 568-581
-
-
Harvey, D.J.1
Sobott, F.2
Crispin, M.3
Wrobel, A.4
Bonomelli, C.5
Vasiljevic, S.6
-
19
-
-
84865496053
-
Ion mobility mass spectrometry of peptide ions: Effects of drift gas and calibration strategies
-
Bush MF, Campuzano IDG, Robinson CV. Ion mobility mass spectrometry of peptide ions: effects of drift gas and calibration strategies. Anal Chem 2012;84:7124-30.
-
(2012)
Anal Chem
, vol.84
, pp. 7124-7130
-
-
Bush, M.F.1
Campuzano, I.D.G.2
Robinson, C.V.3
-
20
-
-
84879367507
-
Effects of traveling wave ion mobility separation on data Independent acquisition in proteomics studies
-
Shliaha PV, Bond NJ, Gatto L, Lilley KS. Effects of traveling wave ion mobility separation on data Independent acquisition in proteomics studies. J Proteome Res 2013;12:2323-39.
-
(2013)
J Proteome Res
, vol.12
, pp. 2323-2339
-
-
Shliaha, P.V.1
Bond, N.J.2
Gatto, L.3
Lilley, K.S.4
-
21
-
-
84896524691
-
Site-specific characterization of (D)-amino acid containing peptide epimers by ion mobility spectrometry
-
Jia C, Lietz CB, Yu Q, Li L. Site-specific characterization of (D)-amino acid containing peptide epimers by ion mobility spectrometry. Anal Chem 2014;86:2972-81.
-
(2014)
Anal Chem
, vol.86
, pp. 2972-2981
-
-
Jia, C.1
Lietz, C.B.2
Yu, Q.3
Li, L.4
-
22
-
-
70349138796
-
The mass-mobility correlation redux: The conformational landscape of anhydrous biomolecules
-
McLean JA. The mass-mobility correlation redux: the conformational landscape of anhydrous biomolecules. J Am Soc Mass Spectrom 2009;20:1775-81.
-
(2009)
J Am Soc Mass Spectrom
, vol.20
, pp. 1775-1781
-
-
McLean, J.A.1
-
23
-
-
84875776771
-
Biomolecular signatures of diabetic wound healing by structural mass spectrometry
-
Hines KM, Ashfaq S, Davidson JM, Opalenik SR, Wikswo JP, McLean JA. Biomolecular signatures of diabetic wound healing by structural mass spectrometry. Anal Chem 2013;85:3651-9.
-
(2013)
Anal Chem
, vol.85
, pp. 3651-3659
-
-
Hines, K.M.1
Ashfaq, S.2
Davidson, J.M.3
Opalenik, S.R.4
Wikswo, J.P.5
McLean, J.A.6
-
24
-
-
84898745525
-
Advancing the high throughput identification of liver fibrosis protein signatures using multiplexed ion mobility spectrometry
-
Baker ES, Burnum-Johnson KE, Jacobs JM, Diamond DL, Brown RN, Ibrahim YM, et al. Advancing the high throughput identification of liver fibrosis protein signatures using multiplexed ion mobility spectrometry. Mol Cell Proteomics 2014;13:1119-27.
-
(2014)
Mol Cell Proteomics
, vol.13
, pp. 1119-1127
-
-
Baker, E.S.1
Burnum-Johnson, K.E.2
Jacobs, J.M.3
Diamond, D.L.4
Brown, R.N.5
Ibrahim, Y.M.6
-
25
-
-
84907637300
-
Structural mass spectrometry of tissue extracts to distinguish cancerous and non-cancerous breast diseases
-
Hines KM, Ballard BR, Marshall DR, McLean JA. Structural mass spectrometry of tissue extracts to distinguish cancerous and non-cancerous breast diseases. Mol Biosyst 2014;10:2827-37.
-
(2014)
Mol Biosyst
, vol.10
, pp. 2827-2837
-
-
Hines, K.M.1
Ballard, B.R.2
Marshall, D.R.3
McLean, J.A.4
-
26
-
-
84856474082
-
Structural mass spectrometry: Rapid methods for separation and analysis of peptide natural products
-
Goodwin CR, Fenn LS, Derewacz DK, Bachmann BO, McLean JA. Structural mass spectrometry: rapid methods for separation and analysis of peptide natural products. J Nat Prod 2012;75:48-53.
-
(2012)
J Nat Prod
, vol.75
, pp. 48-53
-
-
Goodwin, C.R.1
Fenn, L.S.2
Derewacz, D.K.3
Bachmann, B.O.4
McLean, J.A.5
-
27
-
-
80055009017
-
Ion mobility mass spectrometry enables the efficient detection and identification of halogenated natural products from cyanobacteria with minimal sample preparation
-
Esquenazi E, Daly M, Bahrainwala T, Gerwick WH, Dorrestein PC. Ion mobility mass spectrometry enables the efficient detection and identification of halogenated natural products from cyanobacteria with minimal sample preparation. Bioorg Med Chem 2011;19:6639-44.
-
(2011)
Bioorg Med Chem
, vol.19
, pp. 6639-6644
-
-
Esquenazi, E.1
Daly, M.2
Bahrainwala, T.3
Gerwick, W.H.4
Dorrestein, P.C.5
-
28
-
-
84873430621
-
Antimicrobial drug resistance affects broad changes in metabolomic phenotype in addition to secondary metabolism
-
Derewacz DK, Goodwin CR, McNees CR, McLean JA, Bachmann BO. Antimicrobial drug resistance affects broad changes in metabolomic phenotype in addition to secondary metabolism. Proc Natl Acad Sci USA 2013;110:2336-41.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 2336-2341
-
-
Derewacz, D.K.1
Goodwin, C.R.2
McNees, C.R.3
McLean, J.A.4
Bachmann, B.O.5
-
29
-
-
84898910545
-
Ion mobility derived collision cross sections to support metabolomics applications
-
Paglia G, Williams JP, Menikarachchi L, Thompson JW, Tyldesley-Worster R, Halldórsson S, et al. Ion mobility derived collision cross sections to support metabolomics applications. Anal Chem 2014;86:3985-93.
-
(2014)
Anal Chem
, vol.86
, pp. 3985-3993
-
-
Paglia, G.1
Williams, J.P.2
Menikarachchi, L.3
Thompson, J.W.4
Tyldesley-Worster, R.5
Halldórsson, S.6
-
30
-
-
84886053710
-
LC-IMS-MS feature finder: Detecting multidimensional liquid chromatography, ion mobility and mass spectrometry features in complex datasets
-
Crowell KL, Slysz GW, Baker ES, LaMarche BL, Monroe ME, Ibrahim YM, et al. LC-IMS-MS feature finder: detecting multidimensional liquid chromatography, ion mobility and mass spectrometry features in complex datasets. Bioinformatics 2013;29:2804-5.
-
(2013)
Bioinformatics
, vol.29
, pp. 2804-2805
-
-
Crowell, K.L.1
Slysz, G.W.2
Baker, E.S.3
LaMarche, B.L.4
Monroe, M.E.5
Ibrahim, Y.M.6
-
31
-
-
84878878785
-
Amphitrite: A program for processing travelling wave ion mobility mass spectrometry data
-
Sivalingam GN, Yan J, Sahota H, Thalassinos K. Amphitrite: a program for processing travelling wave ion mobility mass spectrometry data. Int J Mass Spectrom 2013;345-347:54-62.
-
(2013)
Int J Mass Spectrom
, vol.345-347
, pp. 54-62
-
-
Sivalingam, G.N.1
Yan, J.2
Sahota, H.3
Thalassinos, K.4
-
32
-
-
84863697677
-
From single cells to deep phenotypes in cancer
-
Bendall SC, Nolan GP. From single cells to deep phenotypes in cancer. Nat Biotechnol 2012;30:639-47.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 639-647
-
-
Bendall, S.C.1
Nolan, G.P.2
-
33
-
-
80054768631
-
Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE
-
Qiu P, Simonds EF, Bendall SC, Gibbs KD Jr, Bruggner RV, Linderman MD, et al. Extracting a cellular hierarchy from high-dimensional cytometry data with SPADE. Nat Biotechnol 2011;29:886-91.
-
(2011)
Nat Biotechnol
, vol.29
, pp. 886-891
-
-
Qiu, P.1
Simonds, E.F.2
Bendall, S.C.3
Gibbs, K.D.4
Bruggner, R.V.5
Linderman, M.D.6
-
34
-
-
84903714301
-
Phenotypic mapping of metabolic profiles using self-organizing maps of high-dimensional mass spectrometry data
-
Goodwin CR, Sherrod SD, Marasco CC, Bachmann BO, Schramm-Sapyta N, Wikswo JP, McLean, JA. Phenotypic mapping of metabolic profiles using self-organizing maps of high-dimensional mass spectrometry data. Anal Chem 2014;86:6563-71.
-
(2014)
Anal Chem
, vol.86
, pp. 6563-6571
-
-
Goodwin, C.R.1
Sherrod, S.D.2
Marasco, C.C.3
Bachmann, B.O.4
Schramm-Sapyta, N.5
Wikswo, J.P.6
McLean, J.A.7
-
35
-
-
38849104440
-
UPLC-ESI-TOFMS-based metabolomics and gene expression dynamics inspector self-organizing metabolomic maps as tools for understanding the cellular response to ionizing radiation
-
Patterson AD, Li H, Eichler GS, Krausz KW, Weinstein JN, Fornace AJ Jr, et al. UPLC-ESI-TOFMS-based metabolomics and gene expression dynamics inspector self-organizing metabolomic maps as tools for understanding the cellular response to ionizing radiation. Anal Chem 2008;80:665-74.
-
(2008)
Anal Chem
, vol.80
, pp. 665-674
-
-
Patterson, A.D.1
Li, H.2
Eichler, G.S.3
Krausz, K.W.4
Weinstein, J.N.5
Fornace, A.J.6
-
36
-
-
84882268761
-
Engineering challenges for instrumenting and controlling integrated organ-on-chip systems
-
Wikswo JP, Block FE, Cliffel DE, Goodwin CR, Marasco CC, Markov DA, et al. Engineering challenges for instrumenting and controlling integrated organ-on-chip systems. IEEE Trans Biomed Eng 2013;60:682-90.
-
(2013)
IEEE Trans Biomed Eng
, vol.60
, pp. 682-690
-
-
Wikswo, J.P.1
Block, F.E.2
Cliffel, D.E.3
Goodwin, C.R.4
Marasco, C.C.5
Markov, D.A.6
-
37
-
-
84891367431
-
Neurovascular unit on a chip: Implications for translational applications
-
Alcendor DJ, Block FE 3rd, Cliffel DE, Daniels JS, Ellacott KL, Goodwin CR, et al. Neurovascular unit on a chip: implications for translational applications. Stem Cell Res Ther 2013;4(Suppl 1):S18.
-
(2013)
Stem Cell Res Ther
, vol.4
, pp. S18
-
-
Alcendor, D.J.1
Block, F.E.2
Cliffel, D.E.3
Daniels, J.S.4
Ellacott, K.L.5
Goodwin, C.R.6
-
38
-
-
84879892445
-
Glia co-culture with neurons in microfluidic platforms promotes the formation and stabilization of synaptic contacts
-
Shi M, Majumdar D, Gao Y, Brewer BM, Goodwin CR, McLean JA, et al. Glia co-culture with neurons in microfluidic platforms promotes the formation and stabilization of synaptic contacts. Lab Chip 2013;13:3008-21.
-
(2013)
Lab Chip
, vol.13
, pp. 3008-3021
-
-
Shi, M.1
Majumdar, D.2
Gao, Y.3
Brewer, B.M.4
Goodwin, C.R.5
McLean, J.A.6
-
39
-
-
84930085856
-
Structuring microbial metabolic responses to multiplexed stimuli via self-organizing metabolomics maps
-
Goodwin CR, Covington BC, Derewacz DK, McNees CR, Wikswo JP, McLean JA, et al. Structuring microbial metabolic responses to multiplexed stimuli via self-organizing metabolomics maps. Chem Biol 2015;22:661-70.
-
(2015)
Chem Biol
, vol.22
, pp. 661-670
-
-
Goodwin, C.R.1
Covington, B.C.2
Derewacz, D.K.3
McNees, C.R.4
Wikswo, J.P.5
McLean, J.A.6
|