UPLC-ESI-TOFMS-based metabolomics and gene expression dynamics inspector self-organizing metabolomic maps as tools for understanding the cellular response to ionizing radiation

Analytical Chemistry

Volumn 80, Issue 3, 2008, Pages 665-674

  Patterson, Andrew D ^a   Li, Henghong ^b   Eichler, Gabriel S ^a   Krausz, Kristopher W ^a   Weinstein, John N ^a   Fornace Jr , Albert J ^b   Gonzalez, Frank J ^a   Idle, Jeffrey R ^c  

^a NATIONAL CANCER INSTITUTE   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; HYDROPHOBICITY; IONIZING RADIATION; LIQUID CHROMATOGRAPHY; METABOLISM; SELF ORGANIZING MAPS;

HYDROPHILIC METABOLOME; IRRADIATED CELLS; METABOLITE CONCENTRATIONS; METABOLOMICS;

GENE EXPRESSION;

ADENOSINE PHOSPHATE; GLUTATHIONE; NICOTINAMIDE ADENINE DINUCLEOTIDE; SPERMINE;

ALGORITHM; ARTICLE; CONTROLLED STUDY; DNA REPAIR; ELECTROSPRAY MASS SPECTROMETRY; FIBROBLAST CULTURE; GENE EXPRESSION; HUMAN; HUMAN CELL; IONIZING RADIATION; LIQUID CHROMATOGRAPHY; METABOLOMICS; PROTEOMICS; RADIATION DOSE; TANDEM MASS SPECTROMETRY; TIME OF FLIGHT MASS SPECTROMETRY; TRANSCRIPTOMICS;

ADENOSINE MONOPHOSPHATE; CELL LINE, TUMOR; CHROMATOGRAPHY, LIQUID; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, RADIATION; GENE EXPRESSION REGULATION; GLUTATHIONE; HUMANS; MULTIVARIATE ANALYSIS; NAD; OXIDATIVE STRESS; RADIATION, IONIZING; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; SPERMINE; TANDEM MASS SPECTROMETRY; TIME FACTORS;

EID: 38849104440     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac701807v     Document Type: Article

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