TREM2 Overexpression has No Improvement on Neuropathology and Cognitive Impairment in Aging APPswe/PS1dE9 Mice

Molecular Neurobiology

Volumn 54, Issue 2, 2017, Pages 855-865

  Jiang, Teng ^a,b   Wan, Yu ^c   Zhang, Ying Dong ^a   Zhou, Jun Shan ^a   Gao, Qing ^a   Zhu, Xi Chen ^d   Shi, Jian Quan ^a   Lu, Huan ^d   Tan, Lan ^c,d   Yu, Jin Tai ^b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c QINGDAO UNIVERSITY   (China)

^d NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Aging; Alzheimer s disease; Amyloid ; Cognitive impairment; Microglia; Phagocytosis; TREM2

Indexed keywords

AMYLOID BETA PROTEIN; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; AMYLOID PRECURSOR PROTEIN; IMMUNOGLOBULIN RECEPTOR; MEMBRANE PROTEIN; PRESENILIN 1; TREM2 PROTEIN, MOUSE;

ADULT; AGING; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; GENE OVEREXPRESSION; IN VITRO STUDY; IN VIVO STUDY; MICROGLIA; MIDDLE AGED; MOUSE; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; PHAGOCYTOSIS; PROTEIN EXPRESSION; ANIMAL; BIOSYNTHESIS; BRAIN; C57BL MOUSE; GENE EXPRESSION; GENETICS; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE;

AGING; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; COGNITIVE DYSFUNCTION; GENE EXPRESSION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PRESENILIN-1; RECEPTORS, IMMUNOLOGIC;

EID: 84954422340     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-016-9704-x     Document Type: Article

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