Reduced mitochondrial ROS, enhanced antioxidant defense, and distinct age-related changes in oxidative damage in muscles of long-lived Peromyscus leucopus

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 304, Issue 5, 2013, Pages

  Shi, Yun ^a,b   Pulliam, Daniel A ^a,b   Liu, Yuhong ^a,b   Hamilton, Ryan T ^a,b   Jernigan, Amanda L ^a,b   Bhattacharya, Arunabh ^a,b   Sloane, Lauren B ^a   Qi, Wenbo ^a,b   Chaudhuri, Asish ^a,b,c   Buffenstein, Rochelle ^a,b   Ungvari, Zoltan ^d   Austad, Steven N ^a,b   van Remmen, Holly ^a,b,c  

^a UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^b Mays Cancer Center at UT Health San Antonio   (United States)

^c SOUTH TEXAS VETERANS HEALTH CARE SYSTEM   (United States)

^d UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

Author keywords

Comparative biology of aging; Mitochondria; Oxidative damage; Peromyscus leucopus; Reactive oxygen species; Skeletal muscle

Indexed keywords

ANTIOXIDANT; CARBONYL DERIVATIVE; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE 1; HYDROGEN PEROXIDE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

AGING; ANIMAL EXPERIMENT; ARTICLE; ENZYME ACTIVITY; FEMALE; LIPID PEROXIDATION; MOUSE; MUSCLE MITOCHONDRION; NONHUMAN; OXIDATIVE STRESS; PEROMYSCUS; PEROMYSCUS LEUCOPUS; PREDICTION; PRIORITY JOURNAL; PROTEIN HOMEOSTASIS; SKELETAL MUSCLE;

AGING; ANIMALS; ANTIOXIDANTS; BASAL METABOLISM; BODY COMPOSITION; CATALASE; ELECTRON TRANSPORT COMPLEX I; ELECTRON TRANSPORT COMPLEX II; ELECTRON TRANSPORT COMPLEX III; ELECTRON TRANSPORT COMPLEX IV; FEMALE; GLUTATHIONE PEROXIDASE; GLYCOLYSIS; LONGEVITY; MICE; MICE, INBRED C57BL; MITOCHONDRIA; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; OXIDATIVE STRESS; PEROMYSCUS; REACTIVE OXYGEN SPECIES; SPECIES SPECIFICITY; SUPEROXIDE DISMUTASE;

EID: 84874635159     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00139.2012     Document Type: Article

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