High-Fat Diet Induced Anxiety and Anhedonia: Impact on Brain Homeostasis and Inflammation

Neuropsychopharmacology

Volumn 41, Issue 7, 2016, Pages 1874-1887

  Dutheil, Sophie ^a   Ota, Kristie T ^a   Wohleb, Eric S ^a   Rasmussen, Kurt ^b   Duman, Ronald S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

A 804598; ADAM17 PROTEIN; CORTICOSTERONE; CYP11B1 PROTEIN; GLUCOSE; INSULIN; INSULIN RECEPTOR; INTERLEUKIN 1BETA; INTERLEUKIN 6; KETAMINE; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN; PROTEIN KINASE B; PURINERGIC P2X RECEPTOR ANTAGONIST; PURINERGIC P2X7 RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; 2-CYANO-1-((1S)-1-PHENYLETHYL)-3-QUINOLIN-5-YLGUANIDINE; GUANIDINE DERIVATIVE; QUINOLINE DERIVATIVE;

ANHEDONIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDEPRESSANT ACTIVITY; ANXIETY; ARTICLE; BRAIN FUNCTION; CALORIC INTAKE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CORTICOSTERONE RELEASE; CYTOKINE PRODUCTION; DEPRESSION; ENZYME PHOSPHORYLATION; FEMALE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; GLUCOSE INTOLERANCE; HIPPOCAMPUS; HOMEOSTASIS; INFLAMMATION; INNATE IMMUNITY; INSULIN RESISTANCE; INTRACELLULAR SIGNALING; LATENT PERIOD; LIPID DIET; LOCOMOTION; MALE; NERVE CELL PLASTICITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; WEIGHT GAIN; WESTERN BLOTTING; ANIMAL; BLOOD; BODY WEIGHT; BRAIN; CHEMICALLY INDUCED; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; EXPLORATORY BEHAVIOR; FEEDING BEHAVIOR; FOOD PREFERENCE; GENE EXPRESSION REGULATION; HYPERGLYCEMIA; METABOLISM; PATHOLOGY; RADIATION RESPONSE; RECOGNITION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANHEDONIA; ANIMALS; ANXIETY; BODY WEIGHT; BRAIN; CORTICOSTERONE; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; FEEDING BEHAVIOR; FOOD PREFERENCES; GENE EXPRESSION REGULATION; GUANIDINES; HYPERGLYCEMIA; INFLAMMATION; MALE; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; RECOGNITION (PSYCHOLOGY); SIGNAL TRANSDUCTION;

EID: 84954357678     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2015.357     Document Type: Article

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