-
1
-
-
80053204468
-
Traumatic brain injury in the United States: Emergency department visits
-
Centers for Disease Control and Prevention: Atlanta
-
Faul, M., Xu, L., Wald, M.M., and Coronado, V.G. (2010). Traumatic Brain Injury in the United States: Emergency Department Visits, Hospitalizations and Deaths 2002-2006. Centers for Disease Control and Prevention: Atlanta
-
(2010)
Hospitalizations and Deaths
, pp. 2002-2006
-
-
Faul, M.1
Xu, L.2
Wald, M.M.3
Coronado, V.G.4
-
3
-
-
0141790099
-
Patient age and outcome following severe traumatic brain injury: An analysis of 5600 patients
-
Hukkelhoven, C.W., Steyerberg, E.W., Rampen, A.J., Farace, E., Habbema, J.D., Marshall, L.F., Murray, G.D., and Maas, A.I. (2003). Patient age and outcome following severe traumatic brain injury: an analysis of 5600 patients. J. Neurosurg. 99, 666-673.
-
(2003)
J. Neurosurg
, vol.99
, pp. 666-673
-
-
Hukkelhoven, C.W.1
Steyerberg, E.W.2
Rampen, A.J.3
Farace, E.4
Habbema, J.D.5
Marshall, L.F.6
Murray, G.D.7
Maas, A.I.8
-
4
-
-
77953288818
-
Mortality reduction after implementing a clinical practice guidelines-based management protocol for severe traumatic brain injury
-
Arabi, Y.M., Haddad, S., Tamim, H.M., Al-Dawood, A., Al-Qahtani, S., Ferayan, A., Al-Abdulmughni, I., Al-Oweis, J., and Rugaan, A. (2010). Mortality reduction after implementing a clinical practice guidelines-based management protocol for severe traumatic brain injury. J. Crit. Care. 25, 190-195.
-
(2010)
J. Crit. Care
, vol.25
, pp. 190-195
-
-
Arabi, Y.M.1
Haddad, S.2
Tamim, H.M.3
Al-Dawood, A.4
Al-Qahtani, S.5
Ferayan, A.6
Al-Abdulmughni, I.7
Al-Oweis, J.8
Rugaan, A.9
-
5
-
-
85009295914
-
Clinical significance of CSF glutamate concentrations following severe traumatic brain injury in humans
-
Brown, J.I., Baker, A.J., Konasiewicz, S.J., and Moulton, R.J. (1998). Clinical significance of CSF glutamate concentrations following severe traumatic brain injury in humans. J. Neurotrauma. 15, 253-263.
-
(1998)
J. Neurotrauma
, vol.15
, pp. 253-263
-
-
Brown, J.I.1
Baker, A.J.2
Konasiewicz, S.J.3
Moulton, R.J.4
-
6
-
-
0023819437
-
High-dose barbiturate control of elevated intracranial pressure in patients with severe head injury
-
Eisenberg, H.M., Frankowski, R.F., Contant, C.F., Marshall, L.F., and Walker, M.D. (1988). High-dose barbiturate control of elevated intracranial pressure in patients with severe head injury. J. Neurosurg. 69, 15-23.
-
(1988)
J. Neurosurg
, vol.69
, pp. 15-23
-
-
Eisenberg, H.M.1
Frankowski, R.F.2
Contant, C.F.3
Marshall, L.F.4
Walker, M.D.5
-
7
-
-
0028805577
-
Pitfalls and advances from the international tirilazad trial in moderate and severe head injury
-
Marshall, L.F., and Marshall, S.B. (1995). Pitfalls and advances from the international tirilazad trial in moderate and severe head injury. J. Neurotrauma. 12, 929-932.
-
(1995)
J. Neurotrauma
, vol.12
, pp. 929-932
-
-
Marshall, L.F.1
Marshall, S.B.2
-
8
-
-
0033388098
-
Failure of the competitive N-methyl-Daspartate antagonist Selfotel (CGS 19755) in the treatment of severe head injury: Results of two phase III clinical trials
-
Morris, G.F., Bullock, R., Marshall, S.B., Marmarou, A., Maas, A., and Marshall, L.F. (1999). Failure of the competitive N-methyl-Daspartate antagonist Selfotel (CGS 19755) in the treatment of severe head injury: results of two phase III clinical trials. The Selfotel Investigators. J. Neurosurg. 91, 737-743.
-
(1999)
The Selfotel Investigators. J. Neurosurg
, vol.91
, pp. 737-743
-
-
Morris, G.F.1
Bullock, R.2
Marshall, S.B.3
Marmarou, A.4
Maas, A.5
Marshall, L.F.6
-
9
-
-
0028785514
-
PEG-SOD after head injury
-
Muizelaar, J.P., Kupiec, J.W., and Rapp, L.A. (1995). PEG-SOD after head injury. J. Neurosurg. 83, 942.
-
(1995)
J. Neurosurg
, vol.83
, pp. 942
-
-
Muizelaar, J.P.1
Kupiec, J.W.2
Rapp, L.A.3
-
10
-
-
0029969691
-
Nimodipine in traumatic subarachnoid haemorrhage: A re-Analysis of the HIT i and HIT II trials
-
Murray, G.D., Teasdale, G.M., and Schmitz, H. (1996). Nimodipine in traumatic subarachnoid haemorrhage: a re-Analysis of the HIT I and HIT II trials. Acta Neurochir. (Wien) 138, 1163-1167.
-
(1996)
Acta Neurochir. (Wien
, vol.138
, pp. 1163-1167
-
-
Murray, G.D.1
Teasdale, G.M.2
Schmitz, H.3
-
11
-
-
0021714069
-
The University of Toronto head injury treatment study: A prospective, randomized comparison of pentobarbital and mannitol
-
Schwartz, M.L., Tator, C.H., Rowed, D.W., Reid, S.R., Meguro, K.,and Andrews, D.F. (1984). The University of Toronto head injury treatment study: a prospective, randomized comparison of pentobarbital and mannitol. Can. J. Neurol. Sci. 11, 434-440.
-
(1984)
Can. J. Neurol. Sci
, vol.11
, pp. 434-440
-
-
Schwartz, M.L.1
Tator, C.H.2
Rowed, D.W.3
Reid, S.R.4
Meguro, K.5
Andrews, D.F.6
-
12
-
-
0026710102
-
A randomized trial of nimodipine in severe head injury: HIT i
-
British/Finnish Co-operative Head Injury Trial Group
-
Teasdale, G., Bailey, I., Bell, A., Gray, J., Gullan, R., Heiskanan, O., Marks, P.V., Marsh, H., Mendelow, D.A., Murray, G. and et al. (1992) A randomized trial of nimodipine in severe head injury: HIT I. British/Finnish Co-operative Head Injury Trial Group. J. Neurotrauma 9 Suppl. 2, S545-S550.
-
(1992)
J. Neurotrauma 9 Suppl
, vol.2
, pp. S545-S550
-
-
Teasdale, G.1
Bailey, I.2
Bell, A.3
Gray, J.4
Gullan, R.5
Heiskanan, O.6
Marks, P.V.7
Marsh, H.8
Mendelow, D.A.9
Murray, G.10
-
13
-
-
0021915533
-
Failure of prophylactic barbiturate coma in the treatment of severe head injury
-
Ward, J.D., Becker, D.P., Miller, J.D., Choi, S.C., Marmarou, A., Wood, C., Newlon, P.G., and Keenan, R. (1985). Failure of prophylactic barbiturate coma in the treatment of severe head injury. J. Neurosurg. 62, 383-388.
-
(1985)
J. Neurosurg
, vol.62
, pp. 383-388
-
-
Ward, J.D.1
Becker, D.P.2
Miller, J.D.3
Choi, S.C.4
Marmarou, A.5
Wood, C.6
Newlon, P.G.7
Keenan, R.8
-
14
-
-
84920059259
-
Very early administration of progesterone for acute traumatic brain injury
-
Wright, D.W., Yeatts, S.D., Silbergleit, R., Palesch, Y.Y., Hertzberg, V.S., Frankel, M., Goldstein, F.C., Caveney, A.F., Howlett-Smith, H., Bengelink, E.M., Manley, G.T., Merck, L.H., Janis, L.S., and Barsan, W.G. (2014). Very early administration of progesterone for acute traumatic brain injury. N. Engl. J. Med. 371, 2457-2466.
-
(2014)
N. Engl. J. Med
, vol.371
, pp. 2457-2466
-
-
Wright, D.W.1
Yeatts, S.D.2
Silbergleit, R.3
Palesch, Y.Y.4
Hertzberg, V.S.5
Frankel, M.6
Goldstein, F.C.7
Caveney, A.F.8
Howlett-Smith, H.9
Bengelink, E.M.10
Manley, G.T.11
Merck, L.H.12
Janis, L.S.13
Barsan, W.G.14
-
15
-
-
72049119592
-
Targeting regulation of ABC efflux transporters in brain diseases: A novel therapeutic approach
-
Potschka, H. (2010). Targeting regulation of ABC efflux transporters in brain diseases: a novel therapeutic approach. Pharmacol. Ther. 125, 118-127.
-
(2010)
Pharmacol. Ther
, vol.125
, pp. 118-127
-
-
Potschka, H.1
-
16
-
-
0036605677
-
Functional expression and localization of P-glycoprotein at the blood brain barrier
-
Bendayan, R., Lee, G., and Bendayan, M. (2002). Functional expression and localization of P-glycoprotein at the blood brain barrier. Microsc. Res. Tech. 57, 365-380.
-
(2002)
Microsc. Res. Tech
, vol.57
, pp. 365-380
-
-
Bendayan, R.1
Lee, G.2
Bendayan, M.3
-
17
-
-
1642454475
-
ABC transporters and the blood-brain barrier
-
Begley, D.J. (2004). ABC transporters and the blood-brain barrier. Curr. Pharm. Des. 10, 1295-1312.
-
(2004)
Curr. Pharm. des
, vol.10
, pp. 1295-1312
-
-
Begley, D.J.1
-
18
-
-
77957352509
-
ABC efflux transporters in brain vasculature of Alzheimer's subjects
-
Wijesuriya, H.C., Bullock, J.Y., Faull, R.L., Hladky, S.B., and Barrand, M.A. (2010). ABC efflux transporters in brain vasculature of Alzheimer's subjects. Brain Res, 1358, 228-238.
-
(2010)
Brain Res
, vol.1358
, pp. 228-238
-
-
Wijesuriya, H.C.1
Bullock, J.Y.2
Faull, R.L.3
Hladky, S.B.4
Barrand, M.A.5
-
19
-
-
0037457803
-
Drug efflux transporters in the CNS
-
Sun, H., Dai, H., Shaik, N., and Elmquist, W.F. (2003). Drug efflux transporters in the CNS. Adv. Drug Deliv. Rev. 55, 83-105.
-
(2003)
Adv. Drug Deliv. Rev
, vol.55
, pp. 83-105
-
-
Sun, H.1
Dai, H.2
Shaik, N.3
Elmquist, W.F.4
-
20
-
-
79951933153
-
ABC transporters in the CNS-An inventory
-
Hartz, A.M., and Bauer, B. (2011). ABC transporters in the CNS-An inventory. Curr. Pharm. Biotechnol. 12, 656-673.
-
(2011)
Curr. Pharm. Biotechnol
, vol.12
, pp. 656-673
-
-
Hartz, A.M.1
Bauer, B.2
-
21
-
-
0032950235
-
Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury
-
Clark, R.S., Kochanek, P.M., Chen, M., Watkins, S.C., Marion, D.W., Chen, J., Hamilton, R.L., Loeffert, J.E., and Graham, S.H. (1999). Increases in Bcl-2 and cleavage of caspase-1 and caspase-3 in human brain after head injury. FASEB J. 13, 813-821.
-
(1999)
FASEB J.
, vol.13
, pp. 813-821
-
-
Clark, R.S.1
Kochanek, P.M.2
Chen, M.3
Watkins, S.C.4
Marion, D.W.5
Chen, J.6
Hamilton, R.L.7
Loeffert, J.E.8
Graham, S.H.9
-
22
-
-
34247137869
-
Association of increased cortical soluble abeta42 levels with diffuse plaques after severe brain injury in humans
-
DeKosky, S.T., Abrahamson, E.E., Ciallella, J.R., Paljug, W.R., Wisniewski, S.R., Clark, R.S., and Ikonomovic, M.D. (2007). Association of increased cortical soluble abeta42 levels with diffuse plaques after severe brain injury in humans. Arch. Neurol. 64, 541-544.
-
(2007)
Arch. Neurol
, vol.64
, pp. 541-544
-
-
DeKosky, S.T.1
Abrahamson, E.E.2
Ciallella, J.R.3
Paljug, W.R.4
Wisniewski, S.R.5
Clark, R.S.6
Ikonomovic, M.D.7
-
23
-
-
5044237263
-
Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury
-
Ikonomovic, M.D., Uryu, K., Abrahamson, E.E., Ciallella, J.R., Trojanowski, J.Q., Lee, V.M., Clark, R.S., Marion, D.W., Wisniewski, S.R., and DeKosky, S.T. (2004). Alzheimer's pathology in human temporal cortex surgically excised after severe brain injury. Exp. Neurol. 190, 192-203.
-
(2004)
Exp. Neurol
, vol.190
, pp. 192-203
-
-
Ikonomovic, M.D.1
Uryu, K.2
Abrahamson, E.E.3
Ciallella, J.R.4
Trojanowski, J.Q.5
Lee, V.M.6
Clark, R.S.7
Marion, D.W.8
Wisniewski, S.R.9
DeKosky, S.T.10
-
24
-
-
33751569687
-
Proteolysis consistent with activation of caspase-7 after severe traumatic brain injury in humans
-
Zhang, X., Alber, S., Watkins, S.C., Kochanek, P.M., Marion, D.W., Graham, S.H., and Clark, R.S. (2006). Proteolysis consistent with activation of caspase-7 after severe traumatic brain injury in humans. J. Neurotrauma. 23, 1583-1590.
-
(2006)
J. Neurotrauma
, vol.23
, pp. 1583-1590
-
-
Zhang, X.1
Alber, S.2
Watkins, S.C.3
Kochanek, P.M.4
Marion, D.W.5
Graham, S.H.6
Clark, R.S.7
-
25
-
-
0037927979
-
Caspase-8 expression and proteolysis in human brain after severe head injury
-
Zhang, X., Graham, S.H., Kochanek, P.M.,Marion, D.W., Nathaniel, P.D., Watkins, S.C., and Clark, R.S. (2003). Caspase-8 expression and proteolysis in human brain after severe head injury. FASEB J. 17, 1367-1369.
-
(2003)
FASEB J.
, vol.17
, pp. 1367-1369
-
-
Zhang, X.1
Graham, S.H.2
Kochanek, P.M.3
Marion, D.W.4
Nathaniel, P.D.5
Watkins, S.C.6
Clark, R.S.7
-
26
-
-
6344265573
-
Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain
-
Nies, A.T., Jedlitschky, G., Konig, J., Herold-Mende, C., Steiner, H.H., Schmitt, H.P., and Keppler, D. (2004). Expression and immunolocalization of the multidrug resistance proteins, MRP1-MRP6 (ABCC1-ABCC6), in human brain. Neuroscience. 129, 349-360.
-
(2004)
Neuroscience
, vol.129
, pp. 349-360
-
-
Nies, A.T.1
Jedlitschky, G.2
Konig, J.3
Herold-Mende, C.4
Steiner, H.H.5
Schmitt, H.P.6
Keppler, D.7
-
27
-
-
2342516133
-
Expression and cellular distribution of multidrug resistance-related proteins in the hippocampus of patients with mesial temporal lobe epilepsy
-
Aronica, E., Gorter, J.A., Ramkema, M., Redeker, S., Ozbas-Gerceker, F., van Vliet, E.A., Scheffer, G.L., Scheper, R.J., van der Valk, P., Baayen, J.C., and Troost, D. (2004). Expression and cellular distribution of multidrug resistance-related proteins in the hippocampus of patients with mesial temporal lobe epilepsy. Epilepsia. 45, 441-451.
-
(2004)
Epilepsia
, vol.45
, pp. 441-451
-
-
Aronica, E.1
Gorter, J.A.2
Ramkema, M.3
Redeker, S.4
Ozbas-Gerceker, F.5
Van Vliet, E.A.6
Scheffer, G.L.7
Scheper, R.J.8
Van Der Valk, P.9
Baayen, J.C.10
Troost, D.11
-
28
-
-
59849129439
-
ABC transporter (p-gp/abcb1, mrp1/abcc1, bcrp/abcg2) expression in the developing human cns
-
Daood, M., Tsai, C., Ahdab-Barmada, M., and Watchko, J.F. (2008). ABC transporter (P-gp/ABCB1, MRP1/ABCC1, BCRP/ABCG2) expression in the developing human CNS. Neuropediatrics. 39, 211-218.
-
(2008)
Neuropediatrics
, vol.39
, pp. 211-218
-
-
Daood, M.1
Tsai, C.2
Ahdab-Barmada, M.3
Watchko, J.F.4
-
29
-
-
79953686193
-
Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors
-
Uchida, Y., Ohtsuki, S., Katsukura, Y., Ikeda, C., Suzuki, T., Kamiie, J., and Terasaki, T. (2011). Quantitative targeted absolute proteomics of human blood-brain barrier transporters and receptors. J. Neurochem. 117, 333-345.
-
(2011)
J. Neurochem
, vol.117
, pp. 333-345
-
-
Uchida, Y.1
Ohtsuki, S.2
Katsukura, Y.3
Ikeda, C.4
Suzuki, T.5
Kamiie, J.6
Terasaki, T.7
-
30
-
-
0034829034
-
Efflux of glutathione conjugate of monochlorobimane from striatal and cortical neurons
-
DeCory, H.H., Piech-Dumas, K.M., Sheu, S.S., Federoff, H.J., and Anders, M.W. (2001). Efflux of glutathione conjugate of monochlorobimane from striatal and cortical neurons. Drug Metab. Dispos. 29, 1256-1262.
-
(2001)
Drug Metab. Dispos
, vol.29
, pp. 1256-1262
-
-
DeCory, H.H.1
Piech-Dumas, K.M.2
Sheu, S.S.3
Federoff, H.J.4
Anders, M.W.5
-
31
-
-
33845899686
-
Role of multidrug resistance-Associated protein 1 expression in the in vitro susceptibility of rat nerve cell to unconjugated bilirubin
-
Falcao, A.S., Bellarosa, C., Fernandes, A., Brito, M.A., Silva, R.F., Tiribelli, C., and Brites, D. (2007). Role of multidrug resistance-Associated protein 1 expression in the in vitro susceptibility of rat nerve cell to unconjugated bilirubin. Neuroscience. 144, 878-888.
-
(2007)
Neuroscience
, vol.144
, pp. 878-888
-
-
Falcao, A.S.1
Bellarosa, C.2
Fernandes, A.3
Brito, M.A.4
Silva, R.F.5
Tiribelli, C.6
Brites, D.7
-
32
-
-
84885185261
-
Influence of ATP-binding cassette polymorphisms on neurological outcome after traumatic brain injury
-
Cousar, J.L., Conley, Y.P., Willyerd, F.A., Sarnaik, A.A., Puccio, A.M., Empey, P.E., Kochanek, P.M., Bell, M.J., Okonkwo, D.O., and Clark, R.S. (2013). Influence of ATP-binding cassette polymorphisms on neurological outcome after traumatic brain injury. Neurocrit. Care. 19, 192-198.
-
(2013)
Neurocrit. Care
, vol.19
, pp. 192-198
-
-
Cousar, J.L.1
Conley, Y.P.2
Willyerd, F.A.3
Sarnaik, A.A.4
Puccio, A.M.5
Empey, P.E.6
Kochanek, P.M.7
Bell, M.J.8
Okonkwo, D.O.9
Clark, R.S.10
-
33
-
-
33846703691
-
Portrait of multifaceted transporter, the multidrug resistance-Associated protein 1 (MRP1/ABCC1
-
Bakos, E., and Homolya, L. (2007). Portrait of multifaceted transporter, the multidrug resistance-Associated protein 1 (MRP1/ABCC1). Pflugers Arch. 453, 621-641.
-
(2007)
Pflugers Arch
, vol.453
, pp. 621-641
-
-
Bakos, E.1
Homolya, L.2
-
34
-
-
0036239972
-
Assessment of antioxidant reserves and oxidative stress in cerebrospinal fluid after severe traumatic brain injury in infants and children
-
Bayir, H., Kagan, V.E., Tyurina, Y.Y., Tyurin, V., Ruppel, R.A., Adelson, P.D., Graham, S.H., Janesko, K., Clark, R.S., and Kochanek, P.M. (2002). Assessment of antioxidant reserves and oxidative stress in cerebrospinal fluid after severe traumatic brain injury in infants and children. Pediatr Res. 51, 571-578.
-
(2002)
Pediatr Res
, vol.51
, pp. 571-578
-
-
Bayir, H.1
Kagan, V.E.2
Tyurina, Y.Y.3
Tyurin, V.4
Ruppel, R.A.5
Adelson, P.D.6
Graham, S.H.7
Janesko, K.8
Clark, R.S.9
Kochanek, P.M.10
-
35
-
-
34347230130
-
Glutathione export during apoptosis requires functional multidrug resistance-Associated proteins
-
Hammond, C.L., Marchan, R., Krance, S.M., and Ballatori, N. (2007). Glutathione export during apoptosis requires functional multidrug resistance-Associated proteins. J. Biol. Chem. 282, 14337-14347.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 14337-14347
-
-
Hammond, C.L.1
Marchan, R.2
Krance, S.M.3
Ballatori, N.4
-
36
-
-
39749103417
-
Autophagy is increased after traumatic brain injury in mice and is partially inhibited by the antioxidant gamma-glutamylcysteinyl ethyl ester
-
Lai, Y., Hickey, R.W., Chen, Y., Bayir, H., Sullivan, M.L., Chu, C.T., Kochanek, P.M., Dixon, C.E., Jenkins, L.W., Graham, S.H., Watkins, S.C., and Clark, R.S. (2008). Autophagy is increased after traumatic brain injury in mice and is partially inhibited by the antioxidant gamma-glutamylcysteinyl ethyl ester. J. Cereb. Blood Flow Metab. 28, 540-550.
-
(2008)
J. Cereb. Blood Flow Metab
, vol.28
, pp. 540-550
-
-
Lai, Y.1
Hickey, R.W.2
Chen, Y.3
Bayir, H.4
Sullivan, M.L.5
Chu, C.T.6
Kochanek, P.M.7
Dixon, C.E.8
Jenkins, L.W.9
Graham, S.H.10
Watkins, S.C.11
Clark, R.S.12
-
37
-
-
84900851451
-
Nacetylcysteine amide confers neuroprotection, improves bioenergetics and behavioral outcome following TBI
-
Pandya, J.D., Readnower, R.D., Patel, S.P., Yonutas, H.M., Pauly, J.R., Goldstein, G.A., Rabchevsky, A.G., and Sullivan, P.G. (2014). Nacetylcysteine amide confers neuroprotection, improves bioenergetics and behavioral outcome following TBI. Exp. Neurol. 257, 106-113.
-
(2014)
Exp. Neurol
, vol.257
, pp. 106-113
-
-
Pandya, J.D.1
Readnower, R.D.2
Patel, S.P.3
Yonutas, H.M.4
Pauly, J.R.5
Goldstein, G.A.6
Rabchevsky, A.G.7
Sullivan, P.G.8
-
38
-
-
84925675264
-
Modulation of Pglycoprotein efflux pump: Induction and activation as a therapeutic strategy
-
Silva, R., Vilas-Boas, V., Carmo, H., Dinis-Oliveira, R.J., Carvalho, F., de Lourdes Bastos, M., and Remiao, F. (2015). Modulation of Pglycoprotein efflux pump: induction and activation as a therapeutic strategy. Pharmacol. Ther. 149, 1-123.
-
(2015)
Pharmacol. Ther
, vol.149
, pp. 1-123
-
-
Silva, R.1
Vilas-Boas, V.2
Carmo, H.3
Dinis-Oliveira, R.J.4
Carvalho, F.5
De Lourdes Bastos, M.6
Remiao, F.7
-
39
-
-
84875958482
-
Association of ATP-binding cassette transporter variants with the risk of Alzheimer's disease
-
Cascorbi, I., Fluh, C., Remmler, C., Haenisch, S., Faltraco, F., Grumbt, M., Peters, M., Brenn, A., Thal, D.R., Warzok, R.W., and Vogelgesang, S. (2013). Association of ATP-binding cassette transporter variants with the risk of Alzheimer's disease. Pharmacogenomics. 14, 485-494.
-
(2013)
Pharmacogenomics
, vol.14
, pp. 485-494
-
-
Cascorbi, I.1
Fluh, C.2
Remmler, C.3
Haenisch, S.4
Faltraco, F.5
Grumbt, M.6
Peters, M.7
Brenn, A.8
Thal, D.R.9
Warzok, R.W.10
Vogelgesang, S.11
-
40
-
-
0036128985
-
Role of multidrug transporters in pharmacoresistance to antiepileptic drugs
-
Loscher, W., and Potschka, H. (2002). Role of multidrug transporters in pharmacoresistance to antiepileptic drugs. J. Pharmacol. Exp. Ther. 301, 7-14.
-
(2002)
J. Pharmacol. Exp. Ther
, vol.301
, pp. 7-14
-
-
Loscher, W.1
Potschka, H.2
-
41
-
-
0036156280
-
Drug resistance in epilepsy: Expression of drug resistance proteins in common causes of refractory epilepsy
-
Sisodiya, S.M., Lin, W.R., Harding, B.N., Squier, M.V., and Thom, M. (2002). Drug resistance in epilepsy: expression of drug resistance proteins in common causes of refractory epilepsy. Brain. 125, 22-31.
-
(2002)
Brain
, vol.125
, pp. 22-31
-
-
Sisodiya, S.M.1
Lin, W.R.2
Harding, B.N.3
Squier, M.V.4
Thom, M.5
-
42
-
-
0037431040
-
Association of multidrug resistance in epilepsy with a polymorphism in the drugtransporter gene ABCB1
-
Siddiqui, A., Kerb, R., Weale, M.E., Brinkmann, U., Smith, A., Goldstein, D.B., Wood, N.W., and Sisodiya, S.M. (2003). Association of multidrug resistance in epilepsy with a polymorphism in the drugtransporter gene ABCB1. N. Engl. J. Med. 348, 1442-1448.
-
(2003)
N. Engl. J. Med
, vol.348
, pp. 1442-1448
-
-
Siddiqui, A.1
Kerb, R.2
Weale, M.E.3
Brinkmann, U.4
Smith, A.5
Goldstein, D.B.6
Wood, N.W.7
Sisodiya, S.M.8
-
43
-
-
46949108804
-
The influence of C3435T polymorphism of ABCB1 gene on penetration of phenobarbital across the blood-brain barrier in patients with generalized epilepsy
-
Basic, S., Hajnsek, S., Bozina, N., Filipcic, I., Sporis, D., Mislov, D., and Posavec, A. (2008). The influence of C3435T polymorphism of ABCB1 gene on penetration of phenobarbital across the blood-brain barrier in patients with generalized epilepsy. Seizure. 17, 524-530.
-
(2008)
Seizure
, vol.17
, pp. 524-530
-
-
Basic, S.1
Hajnsek, S.2
Bozina, N.3
Filipcic, I.4
Sporis, D.5
Mislov, D.6
Posavec, A.7
-
44
-
-
63849243164
-
Polymorphism of the MDR1/ABCB1 C3435T drug-Transporter and resistance to anticonvulsant drugs: A meta-Analysis
-
Bournissen, F.G., Moretti, M.E., Juurlink, D.N., Koren, G., Walker, M., and Finkelstein, Y. (2009). Polymorphism of the MDR1/ABCB1 C3435T drug-Transporter and resistance to anticonvulsant drugs: a meta-Analysis. Epilepsia. 50, 898-903.
-
(2009)
Epilepsia
, vol.50
, pp. 898-903
-
-
Bournissen, F.G.1
Moretti, M.E.2
Juurlink, D.N.3
Koren, G.4
Walker, M.5
Finkelstein, Y.6
-
45
-
-
53149117869
-
Differential expression of the multidrug resistance-related proteins ABCb1 and ABCc1 between blood-brain interfaces
-
Gazzin, S., Strazielle, N., Schmitt, C., Fevre-Montange, M., Ostrow, J.D., Tiribelli, C., and Ghersi-Egea, J.F. (2008). Differential expression of the multidrug resistance-related proteins ABCb1 and ABCc1 between blood-brain interfaces. J. Comp. Neurol. 510, 497-507.
-
(2008)
J. Comp. Neurol
, vol.510
, pp. 497-507
-
-
Gazzin, S.1
Strazielle, N.2
Schmitt, C.3
Fevre-Montange, M.4
Ostrow, J.D.5
Tiribelli, C.6
Ghersi-Egea, J.F.7
-
46
-
-
84873407779
-
Early brain injury alters the blood-brain barrier phenotype in parallel with beta-Amyloid and cognitive changes in adulthood
-
Pop, V., Sorensen, D.W., Kamper, J.E., Ajao, D.O., Murphy, M.P., Head, E., Hartman, R.E., and Badaut, J. (2013). Early brain injury alters the blood-brain barrier phenotype in parallel with beta-Amyloid and cognitive changes in adulthood. J. Cereb. Blood Flow Metab. 33, 205-214.
-
(2013)
J. Cereb. Blood Flow Metab
, vol.33
, pp. 205-214
-
-
Pop, V.1
Sorensen, D.W.2
Kamper, J.E.3
Ajao, D.O.4
Murphy, M.P.5
Head, E.6
Hartman, R.E.7
Badaut, J.8
-
47
-
-
0037119402
-
Proteolytic cleavage of the linker region of the human P-glycoprotein modulates its ATPase function
-
Nuti, S.L., and Rao, U.S. (2002). Proteolytic cleavage of the linker region of the human P-glycoprotein modulates its ATPase function. J. Biol. Chem. 277, 29417-29423.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 29417-29423
-
-
Nuti, S.L.1
Rao, U.S.2
-
48
-
-
0033208628
-
Calpain inhibitor causes accumulation of ubiquitinated P-glycoprotein at the cell surface: Possible role of calpain in P-glycoprotein turnover
-
Ohkawa, K., Asakura, T., Takada, K., Sawai, T., Hashizume, Y., Okawa, Y., and Yanaihara, N. (1999). Calpain inhibitor causes accumulation of ubiquitinated P-glycoprotein at the cell surface: possible role of calpain in P-glycoprotein turnover. Int. J. Oncol. 15, 677-686.
-
(1999)
Int. J. Oncol
, vol.15
, pp. 677-686
-
-
Ohkawa, K.1
Asakura, T.2
Takada, K.3
Sawai, T.4
Hashizume, Y.5
Okawa, Y.6
Yanaihara, N.7
-
49
-
-
20044367461
-
GSH inhibits trypsinization of the C-Terminal half of human MRP1
-
Ren, X.Q., Furukawa, T., Nakajima, Y., Takahashi, H., Aoki, S., Sumizawa, T., Haraguchi, M., Kobayashi, M., Chijiiwa, K., and Akiyama, S. (2005). GSH inhibits trypsinization of the C-Terminal half of human MRP1. J. Biol. Chem. 280, 6231-6237.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 6231-6237
-
-
Ren, X.Q.1
Furukawa, T.2
Nakajima, Y.3
Takahashi, H.4
Aoki, S.5
Sumizawa, T.6
Haraguchi, M.7
Kobayashi, M.8
Chijiiwa, K.9
Akiyama, S.10
-
50
-
-
0033954672
-
Caspase-3 mediated neuronal death after traumatic brain injury in rats
-
Clark, R.S., Kochanek, P.M., Watkins, S.C., Chen, M., Dixon, C.E., Seidberg, N.A., Melick, J., Loeffert, J.E., Nathaniel, P.D., Jin, K.L., and Graham, S.H. (2000). Caspase-3 mediated neuronal death after traumatic brain injury in rats. J. Neurochem. 74, 740-753.
-
(2000)
J. Neurochem
, vol.74
, pp. 740-753
-
-
Clark, R.S.1
Kochanek, P.M.2
Watkins, S.C.3
Chen, M.4
Dixon, C.E.5
Seidberg, N.A.6
Melick, J.7
Loeffert, J.E.8
Nathaniel, P.D.9
Jin, K.L.10
Graham, S.H.11
-
51
-
-
0030951668
-
Mechanisms of calpain proteolysis following traumatic brain injury: Implications for pathology and therapy: Implications for pathology and therapy: A review and update
-
Kampfl, A., Posmantur, R.M., Zhao, X., Schmutzhard, E., Clifton, G.L., and Hayes, R.L. (1997). Mechanisms of calpain proteolysis following traumatic brain injury: implications for pathology and therapy: implications for pathology and therapy: a review and update. J. Neurotrauma. 14, 121-134.
-
(1997)
J. Neurotrauma
, vol.14
, pp. 121-134
-
-
Kampfl, A.1
Posmantur, R.M.2
Zhao, X.3
Schmutzhard, E.4
Clifton, G.L.5
Hayes, R.L.6
-
52
-
-
38549103718
-
Trypsin and trypsin-like proteases in the brain: Proteolysis and cellular functions
-
Wang, Y., Luo, W., and Reiser, G. (2008). Trypsin and trypsin-like proteases in the brain: proteolysis and cellular functions. Cell. Mol. Life Sci. 65, 237-252.
-
(2008)
Cell. Mol. Life Sci
, vol.65
, pp. 237-252
-
-
Wang, Y.1
Luo, W.2
Reiser, G.3
-
53
-
-
38049064882
-
Autophagy is increased in mice after traumatic brain injury and is detectable in human brain after trauma and critical illness
-
Clark, R.S., Bayir, H., Chu, C.T., Alber, S.M., Kochanek, P.M., and Watkins, S.C. (2008). Autophagy is increased in mice after traumatic brain injury and is detectable in human brain after trauma and critical illness. Autophagy. 4, 88-90.
-
(2008)
Autophagy
, vol.4
, pp. 88-90
-
-
Clark, R.S.1
Bayir, H.2
Chu, C.T.3
Alber, S.M.4
Kochanek, P.M.5
Watkins, S.C.6
|