메뉴 건너뛰기




Volumn 14, Issue 5, 2013, Pages 485-494

Association of ATP-binding cassette transporter variants with the risk of Alzheimer's disease

Author keywords

amyloid; ABCA1; ABCA7; ABCC2; Alzheimer's; APOE; BRCP; P glycoprotein

Indexed keywords

ABC TRANSPORTER; ABC TRANSPORTER A1; AMYLOID BETA PROTEIN; APOLIPOPROTEIN A4; BREAST CANCER RESISTANCE PROTEIN; DNA; MULTIDRUG RESISTANCE PROTEIN 1;

EID: 84875958482     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.13.18     Document Type: Article
Times cited : (34)

References (52)
  • 1
    • 0037135111 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
    • DOI 10.1126/science.1072994
    • Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 297(5580), 353-356 (2002 (Pubitemid 34790756)
    • (2002) Science , vol.297 , Issue.5580 , pp. 353-356
    • Hardy, J.1    Selkoe, D.J.2
  • 2
    • 67349142021 scopus 로고    scopus 로고
    • Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease
    • Bell RD, Zlokovic BV. Neurovascular mechanisms and blood-brain barrier disorder in Alzheimer's disease. Acta Neuropathol. 118(1), 103-113 (2009
    • (2009) Acta Neuropathol. , vol.118 , Issue.1 , pp. 103-113
    • Bell, R.D.1    Zlokovic, B.V.2
  • 5
    • 0035112889 scopus 로고    scopus 로고
    • B-amyloid efflux mediated by P-glycoprotein
    • Lam FC, Liu R, Lu P et al. b-amyloid efflux mediated by P-glycoprotein. J. Neurochem. 76(4), 1121-1128 (2001
    • (2001) J. Neurochem. , vol.76 , Issue.4 , pp. 1121-1128
    • Lam, F.C.1    Liu, R.2    Lu, P.3
  • 7
    • 67349212434 scopus 로고    scopus 로고
    • P-glycoprotein and breast cancer resistance protein restrict apical-to-basolateral permeability of human brain endothelium to amyloid-b
    • Tai LM, Loughlin AJ, Male DK, Romero IA. P-glycoprotein and breast cancer resistance protein restrict apical-to-basolateral permeability of human brain endothelium to amyloid-b. J. Cereb. Blood Flow Metab. 29(6), 1079-1083 (2009
    • (2009) J. Cereb. Blood Flow Metab. , vol.29 , Issue.6 , pp. 1079-1083
    • Tai, L.M.1    Loughlin, A.J.2    Male, D.K.3    Romero, I.A.4
  • 8
    • 65649142529 scopus 로고    scopus 로고
    • ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Ab (1-40) peptides
    • Xiong H, Callaghan D, Jones A et al. ABCG2 is upregulated in Alzheimer's brain with cerebral amyloid angiopathy and may act as a gatekeeper at the blood-brain barrier for Ab (1-40) peptides. J. Neurosci. 29(17), 5463-5475 (2009
    • (2009) J. Neurosci. , vol.29 , Issue.17 , pp. 5463-5475
    • Xiong, H.1    Callaghan, D.2    Jones, A.3
  • 9
    • 3242785620 scopus 로고    scopus 로고
    • Importance of P-glycoprotein at blood-tissue barriers
    • DOI 10.1016/j.tips.2004.06.002, PII S0165614704001713
    • Fromm MF. Importance of P-glycoprotein at blood-tissue barriers. Trends Pharmacol. Sci. 25(8), 423-429 (2004 (Pubitemid 38981558)
    • (2004) Trends in Pharmacological Sciences , vol.25 , Issue.8 , pp. 423-429
    • Fromm, M.F.1
  • 10
    • 63349094264 scopus 로고    scopus 로고
    • Drug transport across the blood-brain barrier and the impact of breast cancer resistance protein (ABCG2)
    • Nicolazzo JA, Katneni K. Drug transport across the blood-brain barrier and the impact of breast cancer resistance protein (ABCG2). Curr. Top. Med. Chem. 9(2), 130-147 (2009
    • (2009) Curr. Top. Med. Chem. , vol.9 , Issue.2 , pp. 130-147
    • Nicolazzo, J.A.1    Katneni, K.2
  • 12
    • 72849142118 scopus 로고    scopus 로고
    • ABC transporters in drug-refractory epilepsy: Limited clinical significance of pharmacogenetics?
    • Cascorbi I. ABC transporters in drug-refractory epilepsy: limited clinical significance of pharmacogenetics? Clin. Pharmacol. Ther. 87(1), 15-18 (2010
    • (2010) Clin. Pharmacol. Ther. , vol.87 , Issue.1 , pp. 15-18
    • Cascorbi, I.1
  • 13
    • 33745054649 scopus 로고    scopus 로고
    • Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells
    • DOI 10.1097/01.wnr.0000221833.41340.cd, PII 0000175620060626000009
    • Kim WS, Guillemin GJ, Glaros EN, Lim CK, Garner B. Quantitation of ATP-binding cassette subfamily-A transporter gene expression in primary human brain cells. Neuroreport 17(9), 891-896 (2006 (Pubitemid 43869954)
    • (2006) NeuroReport , vol.17 , Issue.9 , pp. 891-896
    • Kim, W.S.1    Guillemin, G.J.2    Glaros, E.N.3    Lim, C.K.4    Garner, B.5
  • 14
    • 51649118169 scopus 로고    scopus 로고
    • ATP-binding cassette transporter A7 regulates processing of amyloid precursor protein in vitro
    • Chan SL, Kim WS, Kwok JB et al. ATP-binding cassette transporter A7 regulates processing of amyloid precursor protein in vitro. J. Neurochem. 106(2), 793-804 (2008
    • (2008) J. Neurochem. , vol.106 , Issue.2 , pp. 793-804
    • Chan, S.L.1    Kim, W.S.2    Kwok, J.B.3
  • 15
    • 33747177861 scopus 로고    scopus 로고
    • ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages
    • Jehle AW, Gardai SJ, Li S et al. ATP-binding cassette transporter A7 enhances phagocytosis of apoptotic cells and associated ERK signaling in macrophages. J. Cell Biol. 174(4), 547-556 (2006
    • (2006) J. Cell Biol. , vol.174 , Issue.4 , pp. 547-556
    • Jehle, A.W.1    Gardai, S.J.2    Li, S.3
  • 16
    • 79955484414 scopus 로고    scopus 로고
    • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
    • Hollingworth P, Harold D, Sims R et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat. Genet. 43(5), 429-435 (2011
    • (2011) Nat. Genet. , vol.43 , Issue.5 , pp. 429-435
    • Hollingworth, P.1    Harold, D.2    Sims, R.3
  • 17
    • 67149124051 scopus 로고    scopus 로고
    • Non-response to antiepileptic pharmacotherapy is associated with the ABCC2 -24C>T polymorphism in young and adult patients with epilepsy
    • Ufer M, Mosyagin I, Muhle H et al. Non-response to antiepileptic pharmacotherapy is associated with the ABCC2 -24C>T polymorphism in young and adult patients with epilepsy. Pharmacogenet. Genomics 19(5), 353-362 (2009
    • (2009) Pharmacogenet. Genomics , vol.19 , Issue.5 , pp. 353-362
    • Ufer, M.1    Mosyagin, I.2    Muhle, H.3
  • 18
    • 2942723107 scopus 로고    scopus 로고
    • The role of P-glycoprotein in cerebral amyloid angiopathy; Implications for the early pathogenesis of Alzheimer's disease
    • Vogelgesang S, Warzok RW, Cascorbi I et al. The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimer's disease. Curr. Alzheimer Res. 1(2), 121-125 (2004
    • (2004) Curr. Alzheimer Res. , vol.1 , Issue.2 , pp. 121-125
    • Vogelgesang, S.1    Warzok, R.W.2    Cascorbi, I.3
  • 19
    • 77951078680 scopus 로고    scopus 로고
    • Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-b in a mouse model of Alzheimer's disease
    • Hartz AM, Miller DS, Bauer B. Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-b in a mouse model of Alzheimer's disease. Mol. Pharmacol. 77(5), 715-723 (2010
    • (2010) Mol. Pharmacol. , vol.77 , Issue.5 , pp. 715-723
    • Hartz, A.M.1    Miller, D.S.2    Bauer, B.3
  • 20
    • 80052672466 scopus 로고    scopus 로고
    • B-Amyloid downregulates MDR1-P-glycoprotein (Abcb1) expression at the blood-brain barrier in mice
    • Brenn A, Grube M, Peters M et al. b-Amyloid downregulates MDR1-P-glycoprotein (Abcb1) expression at the blood-brain barrier in mice. Int. J. Alzheimers Dis. 2011, 690121 (2011
    • (2011) Int. J. Alzheimers Dis. , vol.2011 , pp. 690121
    • Brenn, A.1    Grube, M.2    Peters, M.3
  • 21
    • 3242690331 scopus 로고    scopus 로고
    • Functional evaluation of ABCB1 (P-glycoprotein) polymorphisms: High-speed screening and structure-activity relationship analyses
    • Ishikawa T, Hirano H, Onishi Y, Sakurai A, Tarui S. Functional evaluation of ABCB1 (P-glycoprotein) polymorphisms: high-speed screening and structure-activity relationship analyses. Drug Metab. Pharmacokinet. 19(1), 1-14 (2004
    • (2004) Drug Metab. Pharmacokinet. , vol.19 , Issue.1 , pp. 1-14
    • Ishikawa, T.1    Hirano, H.2    Onishi, Y.3    Sakurai, A.4    Tarui, S.5
  • 22
    • 33749255547 scopus 로고    scopus 로고
    • In vitro transport characteristics discriminate wild type MDR1 (ABCB1) from Ala893Ser and Ala893Thr polymorphisms
    • Schaefer M, Roots I, Gerloff T. In vitro transport characteristics discriminate wild type MDR1 (ABCB1) from Ala893Ser and Ala893Thr polymorphisms. Eur. J. Clin. Pharmacol. 61(9), 718-718 (2005
    • (2005) Eur. J. Clin. Pharmacol. , vol.61 , Issue.9 , pp. 718-718
    • Schaefer, M.1    Roots, I.2    Gerloff, T.3
  • 24
    • 77958065460 scopus 로고    scopus 로고
    • Apolipoprotein e controls ATP-binding cassette transporters in the ischemic brain
    • Elali A, Hermann DM. Apolipoprotein E controls ATP-binding cassette transporters in the ischemic brain. Sci. Signal. 3(142), (2010
    • (2010) Sci. Signal. , vol.3 , pp. 142
    • Elali, A.1    Hermann, D.M.2
  • 27
    • 37249024134 scopus 로고    scopus 로고
    • Sequential influences of leukemia-specific and genetic factors on P-glycoprotein expression in blasts from 817 patients entered into the National Cancer Research Network acute myeloid leukemia 14 and 15 trials
    • DOI 10.1158/1078-0432.CCR-07-1484
    • Seedhouse CH, Grundy M, White P et al. Sequential influences of leukemia-specific and genetic factors on P-glycoprotein expression in blasts from 817 patients entered into the National Cancer Research Network acute myeloid leukemia 14 and 15 trials. Clin. Cancer Res. 13(23), 7059-7066 (2007 (Pubitemid 350276888)
    • (2007) Clinical Cancer Research , vol.13 , Issue.23 , pp. 7059-7066
    • Seedhouse, C.H.1    Grundy, M.2    White, P.3    Li, Y.4    Fisher, J.5    Yakunina, D.6    Moorman, A.V.7    Hoy, T.8    Russell, N.9    Burnett, A.10    Pallis, M.11
  • 28
    • 84865471981 scopus 로고    scopus 로고
    • MiRNAs as mediators of drug resistance
    • Haenisch S, Cascorbi I. miRNAs as mediators of drug resistance. Epigenomics 4(4), 369-381 (2012
    • (2012) Epigenomics , vol.4 , Issue.4 , pp. 369-381
    • Haenisch, S.1    Cascorbi, I.2
  • 29
    • 51249085805 scopus 로고    scopus 로고
    • Association of ABCB1 genetic variants 3435C>T and 2677G>T to ABCB1 mRNA and protein expression in brain tissue from refractory epilepsy patients
    • Mosyagin I, Runge U, Schroeder HW et al. Association of ABCB1 genetic variants 3435C>T and 2677G>T to ABCB1 mRNA and protein expression in brain tissue from refractory epilepsy patients. Epilepsia 49(9), 1555-1561 (2008
    • (2008) Epilepsia , vol.49 , Issue.9 , pp. 1555-1561
    • Mosyagin, I.1    Runge, U.2    Schroeder, H.W.3
  • 30
    • 34248176214 scopus 로고    scopus 로고
    • ABCB1 genotypes and haplotypes in patients with dementia and age-matched non-demented control patients
    • Frankfort SV, Doodeman VD, Bakker R et al. ABCB1 genotypes and haplotypes in patients with dementia and age-matched non-demented control patients. Mol. Neurodegener. 1, 13 (2006
    • (2006) Mol. Neurodegener. , vol.1 , pp. 13
    • Frankfort, S.V.1    Doodeman, V.D.2    Bakker, R.3
  • 32
    • 66849111193 scopus 로고    scopus 로고
    • Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics
    • Innocenti F, Kroetz DL, Schuetz E et al. Comprehensive pharmacogenetic analysis of irinotecan neutropenia and pharmacokinetics. J. Clin. Oncol. 27(16), 2604-2614 (2009
    • (2009) J. Clin. Oncol. , vol.27 , Issue.16 , pp. 2604-2614
    • Innocenti, F.1    Kroetz, D.L.2    Schuetz, E.3
  • 33
    • 78649320874 scopus 로고    scopus 로고
    • Impact of ABCC2 haplotypes on transcriptional and posttranscriptional gene regulation and function
    • Laechelt S, Turrini E, Ruehmkorf A, Siegmund W, Cascorbi I, Haenisch S. Impact of ABCC2 haplotypes on transcriptional and posttranscriptional gene regulation and function. Pharmacogenomics J. 11(1), 25-34 (2011
    • (2011) Pharmacogenomics J , vol.11 , Issue.1 , pp. 25-34
    • Laechelt, S.1    Turrini, E.2    Ruehmkorf, A.3    Siegmund, W.4    Cascorbi, I.5    Haenisch, S.6
  • 34
    • 84859237353 scopus 로고    scopus 로고
    • Genetic association analysis of transporters identifies ABCC2 loci for seizure control in women with epilepsy on first-line antiepileptic drugs
    • Grover S, Gourie-Devi M, Bala K, Sharma S, Kukreti R. Genetic association analysis of transporters identifies ABCC2 loci for seizure control in women with epilepsy on first-line antiepileptic drugs. Pharmacogenet. Genomics 22(6), 447-465 (2012
    • (2012) Pharmacogenet. Genomics , vol.22 , Issue.6 , pp. 447-465
    • Grover, S.1    Gourie-Devi, M.2    Bala, K.3    Sharma, S.4    Kukreti, R.5
  • 35
    • 84864741841 scopus 로고    scopus 로고
    • ABCC2 polymorphisms and haplotype are associated with drug resistance in Chinese epileptic patients
    • Qu J, Zhou BT, Yin JY et al. ABCC2 polymorphisms and haplotype are associated with drug resistance in Chinese epileptic patients. CNS Neurosci. Ther. 18(8), 647-651 (2012
    • (2012) CNS Neurosci. Ther. , vol.18 , Issue.8 , pp. 647-651
    • Qu, J.1    Zhou, B.T.2    Yin, J.Y.3
  • 36
    • 80052772274 scopus 로고    scopus 로고
    • Impact of ABCC2 genotype on antiepileptic drug response in Caucasian patients with childhood epilepsy
    • Ufer M, von Stulpnagel C, Muhle H et al. Impact of ABCC2 genotype on antiepileptic drug response in Caucasian patients with childhood epilepsy. Pharmacogenet. Genomics (2011
    • (2011) Pharmacogenet. Genomics
    • Ufer, M.1    Von Stulpnagel, C.2    Muhle, H.3
  • 37
    • 34250825286 scopus 로고    scopus 로고
    • Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer
    • Han JY, Lim HS, Yoo YK et al. Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer. Cancer 110(1), 138-147 (2007
    • (2007) Cancer , vol.110 , Issue.1 , pp. 138-147
    • Han, J.Y.1    Lim, H.S.2    Yoo, Y.K.3
  • 38
    • 52749088086 scopus 로고    scopus 로고
    • Synergistic interaction of ABCB1 and ABCG2 polymorphisms predicts the prevalence of toxic encephalopathy during anticancer chemotherapy
    • Erdilyi DJ, Kamory E, Csokay B et al. Synergistic interaction of ABCB1 and ABCG2 polymorphisms predicts the prevalence of toxic encephalopathy during anticancer chemotherapy. Pharmacogenomics J. 8(5), 321-327 (2008
    • (2008) Pharmacogenomics J , vol.8 , Issue.5 , pp. 321-327
    • Erdilyi, D.J.1    Kamory, E.2    Csokay, B.3
  • 41
    • 67649649934 scopus 로고    scopus 로고
    • Interaction between HMGCR and ABCA1 cholesterol-related genes modulates Alzheimer's disease risk
    • Rodriguez-Rodriguez E, Mateo I, Infante J et al. Interaction between HMGCR and ABCA1 cholesterol-related genes modulates Alzheimer's disease risk. Brain Res. 1280, 166-171 (2009
    • (2009) Brain Res. , vol.1280 , pp. 166-171
    • Rodriguez-Rodriguez, E.1    Mateo, I.2    Infante, J.3
  • 43
    • 33750591113 scopus 로고    scopus 로고
    • Polymorphism in ABCA1 influences CSF 24S-hydroxycholesterol levels but is not a major risk factor of Alzheimer's disease
    • Kolsch H, Lutjohann D, Jessen F et al. Polymorphism in ABCA1 influences CSF 24S-hydroxycholesterol levels but is not a major risk factor of Alzheimer's disease. Int. J. Mol. Med. 17(5), 791-794 (2006
    • (2006) Int. J. Mol. Med. , vol.17 , Issue.5 , pp. 791-794
    • Kolsch, H.1    Lutjohann, D.2    Jessen, F.3
  • 46
    • 33645805657 scopus 로고    scopus 로고
    • In vitro P-glycoprotein inhibition assays for assessment of clinical drug interaction potential of new drug candidates: A recommendation for probe substrates
    • Rautio J, Humphreys JE, Webster LO et al. In vitro P-glycoprotein inhibition assays for assessment of clinical drug interaction potential of new drug candidates: a recommendation for probe substrates. Drug Metab. Dispos. 34(5), 786-792 (2006
    • (2006) Drug Metab. Dispos. , vol.34 , Issue.5 , pp. 786-792
    • Rautio, J.1    Humphreys, J.E.2    Webster, L.O.3
  • 47
    • 0033753435 scopus 로고    scopus 로고
    • Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: A new type of drug/drug interaction
    • Westphal K, Weinbrenner A, Zschiesche M et al. Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction. Clin. Pharmacol. Ther. 68(4), 345-355 (2000
    • (2000) Clin. Pharmacol. Ther. , vol.68 , Issue.4 , pp. 345-355
    • Westphal, K.1    Weinbrenner, A.2    Zschiesche, M.3
  • 48
    • 0017282517 scopus 로고
    • The menopausal transition: Analysis of LH, FSH, estradiol, and progesterone concentrations during menstrual cycles of older women
    • Sherman BM, West JH, Korenman SG. The menopausal transition: analysis of LH, FSH, estradiol, and progesterone concentrations during menstrual cycles of older women. J. Clin. Endocrinol. Metab. 42(4), 629-636 (1976
    • (1976) J. Clin. Endocrinol. Metab. , vol.42 , Issue.4 , pp. 629-636
    • Sherman, B.M.1    West, J.H.2    Korenman, S.G.3
  • 50
    • 43649086054 scopus 로고    scopus 로고
    • Sex differences in Alzheimer's disease
    • Schmidt R, Kienbacher E, Benke T et al. Sex differences in Alzheimer's disease. Neuropsychiatry 22(1), 1-15 (2008
    • (2008) Neuropsychiatry , vol.22 , Issue.1 , pp. 1-15
    • Schmidt, R.1    Kienbacher, E.2    Benke, T.3
  • 52
    • 84887823295 scopus 로고    scopus 로고
    • Brain-Net. www.brain-net.net


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.