SCOPUS 정보 검색 플랫폼

Volumn 16, Issue 17, 2015, Pages 2433-2436

Gift from Nature: Cyclomarin A Kills Mycobacteria and Malaria Parasites by Distinct Modes of Action

(17) Bürstner, Nathalie a Roggo, Silvio a Ostermann, Nils a Blank, Jutta a Delmas, Cecile a Freuler, Felix a Gerhartz, Bernd a Hinniger, Alexandra a Hoepfner, Dominic a Liechty, Brigitta a Mihalic, Manuel a Murphy, Jason b Pistorius, Dominik a Rottmann, Matthias c Thomas, Jason R b Schirle, Markus b Schmitt, Esther K a

a NOVARTIS PHARMA AG (Switzerland)

b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH (United States)

c SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE (Switzerland)

Author keywords

antiprotozoal agents; cyclomarin; diadenosine triphosphate; malaria; natural products

Indexed keywords

ANTIMALARIAL AGENT; CYCLOMARIN A; DIADENOSINE TRIPHOSPHATE; ENDOPEPTIDASE CLP; UNCLASSIFIED DRUG; ACID ANHYDRIDE HYDROLASE; BACTERIAL PROTEIN; BIOLOGICAL PRODUCT; FRAGILE HISTIDINE TRIAD PROTEIN; OLIGOPEPTIDE; PROTEIN BINDING; TUMOR PROTEIN;

ANTIBACTERIAL ACTIVITY; ANTIMALARIAL ACTIVITY; ARTICLE; CRYSTALLIZATION; DRUG BINDING; DRUG DETERMINATION; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG POTENCY; DRUG TARGETING; ENZYME ACTIVITY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEOMICS; ANTAGONISTS AND INHIBITORS; BINDING SITE; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; GROWTH, DEVELOPMENT AND AGING; HUMAN; IC50; METABOLISM; MOLECULAR DYNAMICS; PROTEIN TERTIARY STRUCTURE;

ACID ANHYDRIDE HYDROLASES; ANTIMALARIALS; BACTERIAL PROTEINS; BINDING SITES; BIOLOGICAL PRODUCTS; ENDOPEPTIDASE CLP; HUMANS; INHIBITORY CONCENTRATION 50; MOLECULAR DYNAMICS SIMULATION; MYCOBACTERIUM TUBERCULOSIS; NEOPLASM PROTEINS; OLIGOPEPTIDES; PLASMODIUM FALCIPARUM; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY;

EID: 84954357176 PISSN: 14394227 EISSN: 14397633 Source Type: Journal
DOI: 10.1002/cbic.201500472 Document Type: Article

Times cited : (40)

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