The histidine triad superfamily of nucleotide-binding proteins

Journal of Cellular Physiology

Volumn 181, Issue 2, 1999, Pages 179-187

  Brenner, Charles ^a   Biecanowski, Pawel ^b   Pace, Helen C ^a   Huebner, Kay ^a  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOTIDE BINDING PROTEIN;

AMINO ACID SEQUENCE; BINDING SITE; CRYSTAL STRUCTURE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN STRUCTURE; REVIEW; SEQUENCE HOMOLOGY; TUMOR SUPPRESSOR GENE;

AMINO ACID SEQUENCE; ANIMALS; HUMANS; HYDROLASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEOTIDES; PROTEIN STRUCTURE, SECONDARY; PROTEINS; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0032883882     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199911)181:2<179::AID-JCP1>3.0.CO;2-8     Document Type: Review

References (56)

1. Abend A, Garrison PN, Barnes LD, Frey PA. 1999. Stereochemical retention of configuration in the action of Fhit on phosphorouschiral substrates. Biochemistry 38:3668-3676.
2. Albers MW, Liu J, Schreiber SL. 1991. Relationship of FKBP to PKCI-2. Nature 351:527.
3. Au-Young J, Hawkins PR, Hillman JL. 1998. Human protein kinase C inhibitor homolog. U.S. patent 5,773,580.
4. 4A): a putative initiator of DNA replication. Cancer Invest 3:465-471.
5. Barnes LD, Garrison PN, Siprashvili Z, Guranowski A, Robinson AK, Ingram SW, Croce CM, Ohta M, Huebner K 1996. Fhit, a putative tumor suppressor in humans, is a dinucleoside 5′,5‴-P-1,P-3-triphosphate hydrolase. Biochemistry 35:11529-11535.
6. Blackburn GM, Liu XH, Rosier A, Brenner C. 1998. Two hydrolase resistant analogues of diadenosine 5′,5‴-p-1,p-3-triphosphate for studies with Fhit, the human fragile histidine triad protein. Nucleosides Nucleotides 17:301-308.
7. Brenner C. 1999. Fhit-substrate complexes: a new paradigm in reversible protein phosphorylation. Phosphorous, Sulfur, and Silicon Vol. 144-146:746-752.
8. Brenner C, Garrison P, Gilmour J, Peisach D, Ringe D, Petsko GA, Lowenstein JM. 1997a. Crystal structures of Hint demonstrate that histidine triad proteins are GalT-related nucleotide-binding proteins. Nat Struct Biol 4:231-238.
9. Brenner C, Pace HC, Garrison PN, Robinson AK, Rosler A, Liu XH, Blackburn GM, Croce CM, Huebner K, Barnes LD. 1997b. Purification and crystallization of complexes modeling the active state of the fragile histidine triad protein. Protein Eng 10:1461-1463.
10. Brzoska PM, Chen HY, Zhu YF, Levin NA, Disatnik MH, Mochly-Rosen D, Murnane JP, Christman MF. 1995. The product of the ataxia-telangiectasia group d complementing gene, atdc, interacts with a protein kinase c substrate and inhibitor. Proc Natl Acad Sci USA 92:7824-7828.
11. Campbell SL, Khosravi-Far R, Rossman KL, Clark GJ, Der CJ. 1998. Increasing complexity of Ras signaling. Oncogene 17:1395-1413.
12. Chen J, Brevet A, Blanquet S, Plateau P. 1998. Control of 5′,5′-dinucleoside triphosphate catabolism by APH1, a Saccharomyces cerevisiae analog of human FHIT. J Bacteriol 180:2345-2349.
13. Cohen AJ, Li FP, Berg S, Marchetto DJ, Tsai S, Jacobs SC, Brown RS. 1979. Hereditary renal-cell carcinoma associated with a chromosomal translocation. N Engl J Med 301:592-595.
14. De Zeeuw CI, Hansel C, Bian F, Koekkoek SK, van Alphen AM, Linden DJ, Oberdick J. 1998. Expression of a protein kinase C inhibitor in Purkinje cells blocks cerebellar LTD and adaptation of the vestibulo-ocular reflex. Neuron 20:495-508.
15. Fraser ED, Walsh MP. 1991. The major endogenous bovine brain protein kinase C inhibitor is a heat-labile protein. FEBS Lett 294: 285-289.
16. Gilmour J, Liang N, Lowenstein JM. 1997. Isolation, cloning and characterization of a low-molecular-mass purine nucleoside- and nucleotide-binding protein. Biochem J 326:471-477.
17. Holm L, Sander C. 1997a. Enzyme HIT. Trends Biochem Sci 22:116-117.
18. Holm L, Sander C. 1997b. New structure - novel fold? Structure 5:165-171.
19. 4A) asymmetrical hydrolase: sequence similarity with the histidine triad (HIT) protein family. Biochem J 312:925-932.
20. Huebner K, Hadaczek P, Siprashvili Z, Druck T, Croce CM. 1997. The FHIT gene, a multiple tumor suppressor gene encompassing the carcinogen sensitive chromosome fragile site, FRA3B. Biochim Biophys Acta Rev Cancer 1332:M65-M70.
21. Huebner K, Garrison PN, Barnes LD, Croce CM. 1998. The role of the FHIT/FRA3B locus in cancer. Annu Rev Genet 32:7-31.
22. Huebner K, Sozzi G, Brenner C, Pierotti MA, Croce CM. 1999. Fhit loss in lung cancer: diagnostic and therapeutic implications. Adv Oncol 15(2):3-10.
23. Inoue H, Ishii H, Alder H, Snyder E, Druck T, Huebner K, Croce CM. 1997. Sequence of the FRA3B common fragile region: implications for the mechanism of FHIT deletion. Proc Natl Acad Sci USA 94:14584-14589.
24. Ji L, Fang B, Yen N, Fong K, Minna JD, Roth JA. 1999. Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus-mediated fragile histidine triad (FHIT) gene J expression. Cancer Res 59:3333-3339.
25. Juengel JL, Meiner MH, Clapper JA, Turzillo AM, Moss GE, Nett TM, Niswender GD. 1998. Steady-state concentrations of mRNA encoding two inhibitors of protein kinase C in bovine luteal tissue. J Reprod Fertil 113:299-305.
26. Klein M. 1997. Studies on the β isoform of protein kinase C and a putative protein kinase C inhibitor which is a member of the highly conserved histidine triad protein family. New York, Columbia University, Ph.D. thesis.
27. Klein MG, Yao Y, Slosberg ED, Lima CD, Doki Y, Weinstein IB. 1998. Characterization of PKCI and comparative studies with FHIT, related members of the HIT protein family. Exp Cell Res 244:26-32.
28. Lima C, Klein MG, Weinstein IB, Hendrickson WA. 1996. Three-dimensional structure of human protein kinase C interacting protein 1, a member of the HIT family of proteins. Proc Natl Acad Sci USA 93:5357-5362.
29. Lima CD, Damico KL, Naday I, Rosenbaum G, Westbrook EM, Hendrickson WA. 1997a. MAD analysis of Fhit, a putative human tumor suppressor from the HIT protein family. Structure 5:763-774.
30. Lima CD, Klein MG, Hendrickson WA. 1997b. Structure-based analysis of catalysis and substrate definition in the HIT protein family. Science 278:286-290.
31. 3A hydrolase. Angew Chem Int Ed 38:1244-1247.
32. McDonald JR, Walsh MP. 1985. Ca2+-binding proteins from bovine brain including a potent inhibitor of protein kinase C. Biochem J 232:559-567.
33. McDonald JR, Gröschel-Stewart U, Walsh MP. 1987. Properties and distribution of the protein inhibitor (Mr 17,000) of protein kinase C. Biochem J 242:695-705.
34. Medawar PB. 1964. Koestler's theory of the creative act. New Statesman 67:950-952.
35. Mozier NM, Zürcher-Neely HA, Guido DM, Mathews WR, Heinrikson RL, Fraser ED, Walsh MP, Pearson JD. 1990. Amino acid sequence of a 12-kDa inhibitor of protein kinase C [retracted by Walsh MP. 1991. Eur J Biochem 200:811]. Eur J Biochem 194:19-23.
36. Mozier NM, Zürcher-Neely HA, Guido DM, Mathews WR, Heinrikson RL, Fraser ED, Walsh MP, Pearson JD. 1990. Amino acid sequence of a 12-kDa inhibitor of protein kinase C [retracted by Walsh MP. 1991. Eur J Biochem 200:811]. Eur J Biochem 194:19-23.
37. Mozier NM, Walsh MP, Pearson JD. 1991. Characterization of a novel zinc binding site of protein kinase C inhibitor-1. FEBS Lett 279: 14-18.
38. Ohta M, Inoue H, Cotticelli MG, Kastury K, Baffa R, Palazzo J, Siprashvili Z, Mori M, McCue P, Druck T, Croce CM, Huebner K. 1996. The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell 84:587-597.
39. Pace HC, Garrison PN, Robinson AK, Barnes LD, Draganescu AAR, Blackburn GM, Siprashvili Z, Croce CM, Huebner K, Brenner C. 1998. Genetic, biochemical, and crystallographic characterization of Fhit-substrate complexes as the active signaling form of Fhit. Proc Natl Acad Sci USA 95:5484-5489.
40. Pearson JD, DeWald DB, Mathews WR, Mozier NM, Zurcher-Neely HA, Heinrikson RL, Morris MA, McCubbin WD, McDonald JR, Fraser ED, Vogel HJ, Kay CM, Walsh MP. 1990. Amino acid sequence and characterization of a protein inhibitor of protein kinase C. J Biol Chem 242:4583-4591.
41. Pekarsky Y, Campiglio M, Siprashvili Z, Druck T, Sedkov Y, Tillib S, Draganescu A, Wermuth P, Rothman JH, Huebner K, Buchberg AM, Mazo A, Brenner C, Croce CM. 1998. Nitrilase and Fhit homologs are encoded as fusion proteins in Drosophila melanogaster and Caenorhabditis elegans. Proc Natl Acad Sci USA 95:8744-8749.
42. 4A) hydrolase from Schizosaccharomyces pombe. Biochem Biophys Acta 1161:139-148.
43. Sard L, Accornero P, Tornielli S, Delia D, Bunone G, Campiglio M, Colombo MP, Gramegna M, Croce CM, Pierotti MA, Sozzi G. 1999. The tumor-suppressor gene FHIT is involved in the regulation of apoptosis and in cell cycle control. Proc Natl Acad Sci USA 96:8489-8492.
44. Seraphin B. 1992. The HIT protein family: a new family of proteins present in prokaryotes yeast and mammals. DNA Sequence 3:177-179.
45. Siprashvili Z, Sozzi G, Barnes LD, McCue P, Robinson AK, Eryomin V, Sard L, Tagliabue E, Greco A, Fusetti L, Schwartz G, Pierotti MA, Croce CM, Huebner K. 1997. Replacement of FHIT in cancer cells suppresses tumorigenicity. Proc Natl Acad Sci USA 94:13771-13776.
46. Sozzi G, Veronese ML, Negrini M, Baffa R, Cotticelli MG, Inoue H, Tornielli S, Pilotti S, De Gregorio L, Pastorini U, Pierotti MA, Ohta M, Huebner K, Croce CM. 1996. The FHIT gene at 3p14.2 is abnormal in lung cancer. Cell 85:17-26.
47. Sozzi G, Huebner K, Croce CM. 1998a. FHIT in human cancer. Adv Cancer Res 74:141-166.
48. Sozzi G, Pastorino U, Moiraghi L, Tagliabue E, Pezzella F, Ghirelli C, Tornielli S, Sard L, Huebner K, Pierotti MA, Croce CM, Pilotti S. 1998b. Loss of FHIT function in lung cancer and preinvasive bronchial lesions. Cancer Res 58:5032-5037.
49. Varshavsky A. 1983. Diadenosine 5′,5‴-P1, P4-tetraphosphate: a pleiotropically acting alarmone? Cell 34:711-712.
50. 3A) in human cultured cells. FEBS Lett 381:32-34.
51. 4A ratio in human cell cultures. FEBS Lett 415:160-162.
52. Walsh MP, 1991. Retraction concerning amino acid sequence of a 12-kDa inhibitor of protein kinase C. Mistaken identity of a protein kinase C inhibitor [retraction of Mozier NM, Zürcher-Neely HA, Guido DM, Mathews WR, Heinrikson RL, Fraser ED, Walsh MP, Pearson JD. 1990. Eur J Biochem 194:19-23]. Eur J Biochem 200:811.
53. Walsh MP, 1991. Retraction concerning amino acid sequence of a 12-kDa inhibitor of protein kinase C. Mistaken identity of a protein kinase C inhibitor [retraction of Mozier NM, Zürcher-Neely HA, Guido DM, Mathews WR, Heinrikson RL, Fraser ED, Walsh MP, Pearson JD. 1990. Eur J Biochem 194:19-23]. Eur J Biochem 200:811.
54. Wedekind JE, Frey PA, Rayment I. 1995. Three-dimensional structure of galactose-1-phosphate uridylyltransferase from Escherichia coli at 1.8 Å resolution. Biochemistry 34:11049-11061.
55. Wittinghofer A. 1998. Signal transduction via Ras. Biol Chem 379: 933-937.
56. Zamecnik PC, Stephenson ML, Janeway CM, Randerath K. 1966. Enzymatic synthesis of diadenosine tetraphosphate and diadenosine triphosphate with a purified lysyl-sRNA synthetase. Biochem Biophys Res Commun 24:91-97.