Recent Positive Selection Drives the Expansion of a Schizophrenia Risk Nonsynonymous Variant at SLC39A8 in Europeans

Schizophrenia Bulletin

Volumn 42, Issue 1, 2016, Pages 178-190

  Li, Ming ^a   Wu, Dong Dong ^a   Yao, Yong Gang ^a,b   Huo, Yong Xia ^a,c   Liu, Jie Wei ^a,d   Su, Bing ^a   Chasman, Daniel I ^e   Chu, Audrey Y ^e   Huang, Tao ^f   Qi, Lu ^e,f   Zheng, Yan ^f   Luo, Xiong Jian ^a  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c ANHUI UNIVERSITY   (China)

^d UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Europe; nonsynonymous SNP; pleiotropic effects; positive selection; schizophrenia; SLC39A8

Indexed keywords

CATION TRANSPORT PROTEIN; ZIP8 PROTEIN, HUMAN;

ALLELE; ASIAN CONTINENTAL ANCESTRY GROUP; BLACK PERSON; CALORIC INTAKE; CAUCASIAN; COLD; GENETIC PREDISPOSITION; GENETIC SELECTION; GENETIC VARIATION; GENETICS; HAPLOTYPE; HUMAN; HYPERTENSION; OBESITY; PROTECTION; RISK; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM;

AFRICAN CONTINENTAL ANCESTRY GROUP; ALLELES; ASIAN CONTINENTAL ANCESTRY GROUP; CATION TRANSPORT PROTEINS; COLD TEMPERATURE; ENERGY INTAKE; EUROPEAN CONTINENTAL ANCESTRY GROUP; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; HAPLOTYPES; HUMANS; HYPERTENSION; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTECTIVE FACTORS; RISK; SCHIZOPHRENIA; SELECTION, GENETIC;

EID: 84954325565     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbv070     Document Type: Article

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