Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function

Schizophrenia Bulletin

Volumn 41, Issue 6, 2015, Pages 1294-1308

  Luo, Xiong Jian ^a   Mattheisen, Manuel ^b,c,d   Li, Ming ^e   Huang, Liang ^f   Rietschel, Marcella ^g   Børglum, Anders D ^b,c,h   Als, Thomas D ^b,c   Van Den Oord, Edwin J ⁱ   Aberg, Karolina A ⁱ   Mors, Ole ^c,h   Mortensen, Preben Bo ^b,c   Luo, Zhenwu ^j,p   Degenhardt, Franziska ^d   Cichon, Sven ^k,l   Schulze, Thomas G ^m,n   Nöthen, Markus M ^d   Su, Bing ^a   Zhao, Zhongming ^o   Gan, Lin ^o   Yao, Yong Gang ^a,q  

^a KUNMING INSTITUTE OF ZOOLOGY   (China)

^b AARHUS UNIVERSITY   (Denmark)

^c iPSYCH   (Denmark)

^d UNIVERSITY OF BONN   (Germany)

^e JOHNS HOPKINS UNIVERSITY   (United States)

^f GANNAN MEDICAL UNIVERSITY   (China)

^g UNIVERSITY OF HEIDELBERG   (Germany)

^h AARHUS UNIVERSITY HOSPITAL   (Denmark)

ⁱ VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^j MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^k UNIVERSITY OF BASEL   (Switzerland)

^l FORSCHUNGSZENTRUM JÜLICH   (Germany)

^m UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

ⁿ LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^o VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^p UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^q INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

more..

Author keywords

Association; eQTL; Hippocampus; Positive selection; Schizophrenia; ZNF323

Indexed keywords

ALLELE; ARTICLE; BAYES THEOREM; CONTROLLED STUDY; DOWN REGULATION; FOLLOW UP; FRONTAL CORTEX; GENE; GENE EXPRESSION; GENE IDENTIFICATION; GENE POOL; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC SELECTION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; INVESTIGATIVE PROCEDURES; LUNG FUNCTION; MAJOR CLINICAL STUDY; PLEIOTROPY; POPULATION GENETICS; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; ZNF323 GENE; FRONTAL LOBE; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; LUNG; METABOLISM; RISK;

DNA BINDING PROTEIN; TRANSCRIPTION FACTOR; ZNF323 PROTEIN, HUMAN;

DNA-BINDING PROTEINS; DOWN-REGULATION; FRONTAL LOBE; GENE EXPRESSION; GENETIC PLEIOTROPY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HIPPOCAMPUS; HUMANS; LUNG; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; RISK; SCHIZOPHRENIA; SELECTION, GENETIC; TRANSCRIPTION FACTORS;

EID: 84938775282     PISSN: 05867614     EISSN: 17451701     Source Type: Journal    
DOI: 10.1093/schbul/sbv017     Document Type: Article

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