메뉴 건너뛰기




Volumn 91, Issue 1, 2016, Pages 50-58

Myeloproliferative neoplasms: A decade of discoveries and treatment advances

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLPHENYLHYDRAZINE; ACETYLSALICYLIC ACID; ANDROGEN; ARSENIC TRIOXIDE; BUSULFAN; CALRETICULIN; CHLORAMBUCIL; CHLORMETHINE; DANAZOL; DAPSONE; FEDRATINIB; HYDROXYUREA; JANUS KINASE 2; JANUS KINASE INHIBITOR; LEAD ACETATE; LENALIDOMIDE; MELPHALAN; MERCAPTOPURINE; MOMELOTINIB; PHOSPHORUS 32; PIPOBROMAN; POMALIDOMIDE; PREDNISONE; PYRIMETHAMINE; RUXOLITINIB; STAT PROTEIN; THALIDOMIDE; TRETAMINE; UNINDEXED DRUG; URAMUSTINE; JAK2 PROTEIN, HUMAN;

EID: 84954285121     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.24221     Document Type: Article
Times cited : (136)

References (152)
  • 1
    • 0001639195 scopus 로고
    • Some speculations on the myeloproliferative syndromes
    • Dameshek W. Some speculations on the myeloproliferative syndromes. Blood 1951;6:372-375.
    • (1951) Blood , vol.6 , pp. 372-375
    • Dameshek, W.1
  • 2
    • 0000358195 scopus 로고
    • Case of hypertrophy of the spleen and liver in which death took place from suppuration of the Blood
    • Bennett JH. Case of hypertrophy of the spleen and liver in which death took place from suppuration of the Blood. Edinburgh Med Surg J 1845;64:413-423.
    • (1845) Edinburgh Med Surg J , vol.64 , pp. 413-423
    • Bennett, J.H.1
  • 3
    • 34447610836 scopus 로고
    • Zwei Falle von Leukamie mit eigenthumlichem Blut- resp. Knochenmarksbefund (Two cases of leukemia with peculiar blood and bone marrow findings, respectively)
    • Heuck G. Zwei Falle von Leukamie mit eigenthumlichem Blut- resp. Knochenmarksbefund (Two cases of leukemia with peculiar blood and bone marrow findings, respectively). Arch Pathol Anat Physiol Virchows 1879;78:475-496.
    • (1879) Arch Pathol Anat Physiol Virchows , vol.78 , pp. 475-496
    • Heuck, G.1
  • 4
    • 0001151440 scopus 로고
    • Sur une forme speciale de cyanose s'accompanant d'hyperglobulie excessive et peristente (On a special form of cyanosis accompanied by excessive and persistent erythrocytosis)
    • 60;1892;4
    • Vaquez H. Sur une forme speciale de cyanose s'accompanant d'hyperglobulie excessive et peristente (On a special form of cyanosis accompanied by excessive and persistent erythrocytosis). Compt Rend Soc De Biol and Suppl Note Bull Et Mem Soc Med D'hop De Paris 3 ser 1895;12: 60;1892;4:384-388.
    • (1895) Compt Rend Soc De Biol and Suppl Note Bull Et Mem Soc Med D'hop De Paris 3 ser , vol.12 , pp. 384-388
    • Vaquez, H.1
  • 5
    • 0000435410 scopus 로고
    • Chronic cyanosis, with polycythemia and enlarged spleen: A new clinical entity
    • Osler W. Chronic cyanosis, with polycythemia and enlarged spleen: A new clinical entity. Am J Med Sci 1903;126:187-201.
    • (1903) Am J Med Sci , vol.126 , pp. 187-201
    • Osler, W.1
  • 6
    • 50249197493 scopus 로고
    • A clinical lecture on erythraemia (polycythaemia with cyanosis, maladie de Vaquez)
    • Osler W. A clinical lecture on erythraemia (polycythaemia with cyanosis, maladie de Vaquez). Lancet 1908;1:143-146.
    • (1908) Lancet , vol.1 , pp. 143-146
    • Osler, W.1
  • 7
    • 34347132671 scopus 로고
    • Hamorrhagische thrombozythamie bei vascularer schrumpfmilz (Hemorrhagic thrombocythemia with a vascular, sclerotic spleen)
    • Epstein E, Goedel A. Hamorrhagische thrombozythamie bei vascularer schrumpfmilz (Hemorrhagic thrombocythemia with a vascular, sclerotic spleen). Virch Arch Pathol Anat Histopathol 1934;293:233-248.
    • (1934) Virch Arch Pathol Anat Histopathol , vol.293 , pp. 233-248
    • Epstein, E.1    Goedel, A.2
  • 9
    • 0017174101 scopus 로고
    • Polycythemia vera: Stem-cell and probable clonal origin of the disease
    • Adamson JW, Fialkow PJ, Murphy S, et al. Polycythemia vera: Stem-cell and probable clonal origin of the disease. N Engl J Med 1976;295:913-916.
    • (1976) N Engl J Med , vol.295 , pp. 913-916
    • Adamson, J.W.1    Fialkow, P.J.2    Murphy, S.3
  • 10
    • 0017812507 scopus 로고
    • Agnogenic myeloid metaplasia: A clonal proliferation of hematopoietic stem cells with secondary myelofibrosis
    • Jacobson RJ, Salo A, Fialkow PJ. Agnogenic myeloid metaplasia: A clonal proliferation of hematopoietic stem cells with secondary myelofibrosis. Blood 1978;51:189-194.
    • (1978) Blood , vol.51 , pp. 189-194
    • Jacobson, R.J.1    Salo, A.2    Fialkow, P.J.3
  • 11
    • 0019818299 scopus 로고
    • Evidence that essential thrombocythemia is a clonal disorder with origin in a multipotent stem cell
    • Fialkow PJ, Faguet GB, Jacobson RJ, et al. Evidence that essential thrombocythemia is a clonal disorder with origin in a multipotent stem cell. Blood 1981;58:916-919.
    • (1981) Blood , vol.58 , pp. 916-919
    • Fialkow, P.J.1    Faguet, G.B.2    Jacobson, R.J.3
  • 12
    • 72849159485 scopus 로고
    • Chromosome studies on normal and leukemic human leukocytes
    • Nowell PC, Hungerford DA. Chromosome studies on normal and leukemic human leukocytes. J Natl Cancer Inst 1960;25:85-109.
    • (1960) J Natl Cancer Inst , vol.25 , pp. 85-109
    • Nowell, P.C.1    Hungerford, D.A.2
  • 13
    • 0000286732 scopus 로고
    • A minute chromosome in human granulocytic leukemia
    • Nowell PC, Hungerford DA. A minute chromosome in human granulocytic leukemia. Science 1960;132:1497.
    • (1960) Science , vol.132 , pp. 1497
    • Nowell, P.C.1    Hungerford, D.A.2
  • 14
    • 0015694748 scopus 로고
    • Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining
    • Rowley JD. Letter: A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining. Nature 1973;243:290-293.
    • (1973) Nature , vol.243 , pp. 290-293
    • Rowley, J.D.1
  • 15
    • 0021802841 scopus 로고
    • Fused transcript of abl and bcr genes in chronic myelogenous leukaemia
    • Shtivelman E, Lifshitz B, Gale RP, et al. Fused transcript of abl and bcr genes in chronic myelogenous leukaemia. Nature 1985;315:550-554.
    • (1985) Nature , vol.315 , pp. 550-554
    • Shtivelman, E.1    Lifshitz, B.2    Gale, R.P.3
  • 16
    • 0022352068 scopus 로고
    • Evidence of a new chimeric bcr/c-abl mRNA in patients with chronic myelocytic leukemia and the Philadelphia chromosome
    • Stam K, Heisterkamp N, Grosveld G, et al. Evidence of a new chimeric bcr/c-abl mRNA in patients with chronic myelocytic leukemia and the Philadelphia chromosome. N Engl J Med 1985;313:1429-1433.
    • (1985) N Engl J Med , vol.313 , pp. 1429-1433
    • Stam, K.1    Heisterkamp, N.2    Grosveld, G.3
  • 17
    • 0022544401 scopus 로고
    • The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene
    • Ben-Neriah Y, Daley GQ, Mes-Masson AM, et al. The chronic myelogenous leukemia-specific P210 protein is the product of the bcr/abl hybrid gene. Science 1986;233:212-214.
    • (1986) Science , vol.233 , pp. 212-214
    • Ben-Neriah, Y.1    Daley, G.Q.2    Mes-Masson, A.M.3
  • 18
    • 0025117392 scopus 로고
    • Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome
    • Daley GQ, Van Etten RA, Baltimore D. Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome. Science 1990;247:824-830.
    • (1990) Science , vol.247 , pp. 824-830
    • Daley, G.Q.1    Van Etten, R.A.2    Baltimore, D.3
  • 19
    • 0029947186 scopus 로고    scopus 로고
    • Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells
    • Druker BJ, Tamura S, Buchdunger E, et al. Effects of a selective inhibitor of the Abl tyrosine kinase on the growth of Bcr-Abl positive cells. Nat Med 1996;2:561-566.
    • (1996) Nat Med , vol.2 , pp. 561-566
    • Druker, B.J.1    Tamura, S.2    Buchdunger, E.3
  • 20
    • 70349256226 scopus 로고    scopus 로고
    • The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: Rationale and important changes
    • Vardiman JW, Thiele J, Arber DA, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: Rationale and important changes. Blood 2009;114:937-951.
    • (2009) Blood , vol.114 , pp. 937-951
    • Vardiman, J.W.1    Thiele, J.2    Arber, D.A.3
  • 21
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera
    • James C, Ugo V, Le Couedic JP, et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005;434:1144-1148.
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3
  • 22
    • 84890328032 scopus 로고    scopus 로고
    • Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2
    • Nangalia J, Massie CE, Baxter EJ, et al. Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2. N Engl J Med 2013;369:2391-2405.
    • (2013) N Engl J Med , vol.369 , pp. 2391-2405
    • Nangalia, J.1    Massie, C.E.2    Baxter, E.J.3
  • 23
    • 84890372480 scopus 로고    scopus 로고
    • Somatic mutations of calreticulin in myeloproliferative neoplasms
    • Klampfl T, Gisslinger H, Harutyunyan AS, et al. Somatic mutations of calreticulin in myeloproliferative neoplasms. N Engl J Med 2013;369:2379-2390.
    • (2013) N Engl J Med , vol.369 , pp. 2379-2390
    • Klampfl, T.1    Gisslinger, H.2    Harutyunyan, A.S.3
  • 24
    • 33746437130 scopus 로고    scopus 로고
    • MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia
    • Pikman Y, Lee BH, Mercher T, et al. MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia. PLoS Med 2006;3:e270.
    • (2006) PLoS Med , vol.3 , pp. e270
    • Pikman, Y.1    Lee, B.H.2    Mercher, T.3
  • 25
    • 20244369569 scopus 로고    scopus 로고
    • Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis
    • Levine RL, Wadleigh M, Cools J, et al. Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. Cancer Cell 2005;7:387-397.
    • (2005) Cancer Cell , vol.7 , pp. 387-397
    • Levine, R.L.1    Wadleigh, M.2    Cools, J.3
  • 26
    • 17644424955 scopus 로고    scopus 로고
    • A gain-of-function mutation of JAK2 in myeloproliferative disorders
    • Kralovics R, Passamonti F, Buser AS, et al. A gain-of-function mutation of JAK2 in myeloproliferative disorders. N Engl J Med 2005;352:1779-1790.
    • (2005) N Engl J Med , vol.352 , pp. 1779-1790
    • Kralovics, R.1    Passamonti, F.2    Buser, A.S.3
  • 27
    • 20144363192 scopus 로고    scopus 로고
    • Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders
    • Baxter EJ, Scott LM, Campbell PJ, et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005;365:1054-1061.
    • (2005) Lancet , vol.365 , pp. 1054-1061
    • Baxter, E.J.1    Scott, L.M.2    Campbell, P.J.3
  • 28
    • 31544477194 scopus 로고    scopus 로고
    • The clinical phenotype of wild-type, heterozygous, and homozygous JAK2V617F in polycythemia vera
    • Tefferi A, Lasho TL, Schwager SM, et al. The clinical phenotype of wild-type, heterozygous, and homozygous JAK2V617F in polycythemia vera. Cancer 2006;106:631-635.
    • (2006) Cancer , vol.106 , pp. 631-635
    • Tefferi, A.1    Lasho, T.L.2    Schwager, S.M.3
  • 29
    • 31444439623 scopus 로고    scopus 로고
    • Detection of JAK2 V617F as a first intention diagnostic test for erythrocytosis
    • James C, Delhommeau F, Marzac C, et al. Detection of JAK2 V617F as a first intention diagnostic test for erythrocytosis. Leukemia 2006;20:350-353.
    • (2006) Leukemia , vol.20 , pp. 350-353
    • James, C.1    Delhommeau, F.2    Marzac, C.3
  • 30
    • 27144443646 scopus 로고    scopus 로고
    • Clinical implications of the JAK2 V617F mutation in essential thrombocythemia
    • Antonioli E, Guglielmelli P, Pancrazzi A, et al. Clinical implications of the JAK2 V617F mutation in essential thrombocythemia. Leukemia 2005;19:1847-1849.
    • (2005) Leukemia , vol.19 , pp. 1847-1849
    • Antonioli, E.1    Guglielmelli, P.2    Pancrazzi, A.3
  • 31
    • 28244442441 scopus 로고    scopus 로고
    • Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: A prospective study
    • Campbell PJ, Scott LM, Buck G, et al. Definition of subtypes of essential thrombocythaemia and relation to polycythaemia vera based on JAK2 V617F mutation status: A prospective study. Lancet 2005;366:1945-1953.
    • (2005) Lancet , vol.366 , pp. 1945-1953
    • Campbell, P.J.1    Scott, L.M.2    Buck, G.3
  • 32
    • 27744606173 scopus 로고    scopus 로고
    • JAK2 mutation in essential thrombocythaemia: Clinical associations and long-term prognostic relevance
    • Wolanskyj AP, Lasho TL, Schwager SM, et al. JAK2 mutation in essential thrombocythaemia: Clinical associations and long-term prognostic relevance. Br J Haematol 2005;131:208-213.
    • (2005) Br J Haematol , vol.131 , pp. 208-213
    • Wolanskyj, A.P.1    Lasho, T.L.2    Schwager, S.M.3
  • 33
    • 34249071097 scopus 로고    scopus 로고
    • Clinical correlates of JAK2V617F allele burden in essential thrombocythemia
    • Kittur J, Knudson RA, Lasho TL, et al. Clinical correlates of JAK2V617F allele burden in essential thrombocythemia. Cancer 2007;109:2279-2284.
    • (2007) Cancer , vol.109 , pp. 2279-2284
    • Kittur, J.1    Knudson, R.A.2    Lasho, T.L.3
  • 34
    • 30844444135 scopus 로고    scopus 로고
    • The JAK2 tyrosine kinase mutation in myelofibrosis with myeloid metaplasia: Lineage specificity and clinical correlates
    • Tefferi A, Lasho TL, Schwager SM, et al. The JAK2 tyrosine kinase mutation in myelofibrosis with myeloid metaplasia: Lineage specificity and clinical correlates. Br J Haematol 2005;131:320-328.
    • (2005) Br J Haematol , vol.131 , pp. 320-328
    • Tefferi, A.1    Lasho, T.L.2    Schwager, S.M.3
  • 35
    • 84908147447 scopus 로고    scopus 로고
    • Long-term survival and blast transformation in molecularly annotated essential thrombocythemia, polycythemia vera, and myelofibrosis
    • quiz 2615.
    • Tefferi A, Guglielmelli P, Larson DR, et al. Long-term survival and blast transformation in molecularly annotated essential thrombocythemia, polycythemia vera, and myelofibrosis. Blood 2014;124:2507-2513. quiz 2615.
    • (2014) Blood , vol.124 , pp. 2507-2513
    • Tefferi, A.1    Guglielmelli, P.2    Larson, D.R.3
  • 36
    • 33846660947 scopus 로고    scopus 로고
    • JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis
    • Scott LM, Tong W, Levine RL, et al. JAK2 exon 12 mutations in polycythemia vera and idiopathic erythrocytosis. N Engl J Med 2007;356:459-468.
    • (2007) N Engl J Med , vol.356 , pp. 459-468
    • Scott, L.M.1    Tong, W.2    Levine, R.L.3
  • 37
    • 84919467186 scopus 로고    scopus 로고
    • Presence of calreticulin mutations in JAK2-negative polycythemia vera
    • Broseus J, Park JH, Carillo S, et al. Presence of calreticulin mutations in JAK2-negative polycythemia vera. Blood 2014;124:3964-3966.
    • (2014) Blood , vol.124 , pp. 3964-3966
    • Broseus, J.1    Park, J.H.2    Carillo, S.3
  • 38
    • 79960343089 scopus 로고    scopus 로고
    • Infrequent occurrence of MPL exon 10 mutations in polycythemia vera and post-polycythemia vera myelofibrosis
    • Pardanani A, Lasho TL, Finke CM, et al. Infrequent occurrence of MPL exon 10 mutations in polycythemia vera and post-polycythemia vera myelofibrosis. Am J Hematol 2011;86:701-702.
    • (2011) Am J Hematol , vol.86 , pp. 701-702
    • Pardanani, A.1    Lasho, T.L.2    Finke, C.M.3
  • 39
    • 84954273092 scopus 로고    scopus 로고
    • Whole exome sequencing identifies novel MPL and JAK2 mutations in triple negative myeloproliferative neoplasms
    • Milosevic Feenstra JD, Nivarthi H, Gisslinger H, et al. Whole exome sequencing identifies novel MPL and JAK2 mutations in triple negative myeloproliferative neoplasms. Blood 2015.
    • (2015) Blood
    • Milosevic Feenstra, J.D.1    Nivarthi, H.2    Gisslinger, H.3
  • 40
    • 84871501896 scopus 로고    scopus 로고
    • Development and validation of an International Prognostic Score of thrombosis in World Health Organization-essential thrombocythemia (IPSET-thrombosis)
    • quiz 5252.
    • Barbui T, Finazzi G, Carobbio A, et al. Development and validation of an International Prognostic Score of thrombosis in World Health Organization-essential thrombocythemia (IPSET-thrombosis). Blood 2012;120:5128-5133. quiz 5252.
    • (2012) Blood , vol.120 , pp. 5128-5133
    • Barbui, T.1    Finazzi, G.2    Carobbio, A.3
  • 41
    • 84904067758 scopus 로고    scopus 로고
    • An overview on CALR and CSF3R mutations and a proposal for revision of WHO diagnostic criteria for myeloproliferative neoplasms
    • Tefferi A, Thiele J, Vannucchi AM, et al. An overview on CALR and CSF3R mutations and a proposal for revision of WHO diagnostic criteria for myeloproliferative neoplasms. Leukemia 2014;28:1407-1413.
    • (2014) Leukemia , vol.28 , pp. 1407-1413
    • Tefferi, A.1    Thiele, J.2    Vannucchi, A.M.3
  • 42
    • 84904401956 scopus 로고    scopus 로고
    • Type 1 versus Type 2 calreticulin mutations in essential thrombocythemia: A collaborative study of 1027 patients
    • Tefferi A, Wassie EA, Guglielmelli P, et al. Type 1 versus Type 2 calreticulin mutations in essential thrombocythemia: A collaborative study of 1027 patients. Am J Hematol 2014;89:E121-E124.
    • (2014) Am J Hematol , vol.89 , pp. E121-E124
    • Tefferi, A.1    Wassie, E.A.2    Guglielmelli, P.3
  • 43
    • 84904046605 scopus 로고    scopus 로고
    • Type 1 vs. type 2 calreticulin mutations in primary myelofibrosis: Differences in phenotype and prognostic impact
    • Tefferi A, Lasho TL, Finke C, et al. Type 1 vs. type 2 calreticulin mutations in primary myelofibrosis: Differences in phenotype and prognostic impact. Leukemia 2014;28:1568-1570.
    • (2014) Leukemia , vol.28 , pp. 1568-1570
    • Tefferi, A.1    Lasho, T.L.2    Finke, C.3
  • 44
    • 84908065771 scopus 로고    scopus 로고
    • The prognostic advantage of calreticulin mutations in myelofibrosis might be confined to type 1 or type 1-like CALR variants
    • Tefferi A, Lasho TL, Tischer A, et al. The prognostic advantage of calreticulin mutations in myelofibrosis might be confined to type 1 or type 1-like CALR variants. Blood 2014;124:2465-2466.
    • (2014) Blood , vol.124 , pp. 2465-2466
    • Tefferi, A.1    Lasho, T.L.2    Tischer, A.3
  • 45
    • 84922693801 scopus 로고    scopus 로고
    • Effect of mutation order on myeloproliferative neoplasms
    • Ortmann CA, Kent DG, Nangalia J, et al. Effect of mutation order on myeloproliferative neoplasms. N Engl J Med 2015;372:601-612.
    • (2015) N Engl J Med , vol.372 , pp. 601-612
    • Ortmann, C.A.1    Kent, D.G.2    Nangalia, J.3
  • 46
    • 84901714382 scopus 로고    scopus 로고
    • Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis
    • Rampal R, Al-Shahrour F, Abdel-Wahab O, et al. Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis. Blood 2014;123:e123-133.
    • (2014) Blood , vol.123 , pp. e123-e133
    • Rampal, R.1    Al-Shahrour, F.2    Abdel-Wahab, O.3
  • 47
    • 84954232267 scopus 로고    scopus 로고
    • Calr Mutants Retroviral Mouse Models Lead to a Myeloproliferative Neoplasm Mimicking an Essential Thrombocythemia Progressing to a Myelofibrosis
    • Marty C, Harini N, Pecquet C, et al. Calr Mutants Retroviral Mouse Models Lead to a Myeloproliferative Neoplasm Mimicking an Essential Thrombocythemia Progressing to a Myelofibrosis. Blood 2014;124:157-157.
    • (2014) Blood , vol.124 , pp. 157-157
    • Marty, C.1    Harini, N.2    Pecquet, C.3
  • 48
    • 84899065964 scopus 로고    scopus 로고
    • Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms
    • Lundberg P, Karow A, Nienhold R, et al. Clonal evolution and clinical correlates of somatic mutations in myeloproliferative neoplasms. Blood 2014;123:2220-2228.
    • (2014) Blood , vol.123 , pp. 2220-2228
    • Lundberg, P.1    Karow, A.2    Nienhold, R.3
  • 49
    • 84920939031 scopus 로고    scopus 로고
    • Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice combine to promote disease progression in myeloproliferative neoplasms
    • Chen E, Schneider RK, Breyfogle LJ, et al. Distinct effects of concomitant Jak2V617F expression and Tet2 loss in mice combine to promote disease progression in myeloproliferative neoplasms. Blood 2015;125:327-335.
    • (2015) Blood , vol.125 , pp. 327-335
    • Chen, E.1    Schneider, R.K.2    Breyfogle, L.J.3
  • 50
    • 84918570809 scopus 로고    scopus 로고
    • Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms
    • Rampal R, Ahn J, Abdel-Wahab O, et al. Genomic and functional analysis of leukemic transformation of myeloproliferative neoplasms. Proc Natl Acad Sci USA 2014;111:E5401-E5410.
    • (2014) Proc Natl Acad Sci USA , vol.111 , pp. E5401-E5410
    • Rampal, R.1    Ahn, J.2    Abdel-Wahab, O.3
  • 51
    • 84883742034 scopus 로고    scopus 로고
    • Mutations and prognosis in primary myelofibrosis
    • Vannucchi AM, Lasho TL, Guglielmelli P, et al. Mutations and prognosis in primary myelofibrosis. Leukemia 2013;27:1861-1869.
    • (2013) Leukemia , vol.27 , pp. 1861-1869
    • Vannucchi, A.M.1    Lasho, T.L.2    Guglielmelli, P.3
  • 52
    • 84893717057 scopus 로고    scopus 로고
    • U2AF1 mutations in primary myelofibrosis are strongly associated with anemia and thrombocytopenia despite clustering with JAK2V617F and normal karyotype
    • Tefferi A, Finke CM, Lasho TL, et al. U2AF1 mutations in primary myelofibrosis are strongly associated with anemia and thrombocytopenia despite clustering with JAK2V617F and normal karyotype. Leukemia 2014;28:431-433.
    • (2014) Leukemia , vol.28 , pp. 431-433
    • Tefferi, A.1    Finke, C.M.2    Lasho, T.L.3
  • 53
    • 77958021645 scopus 로고    scopus 로고
    • LNK mutation studies in blast-phase myeloproliferative neoplasms, and in chronic-phase disease with TET2, IDH, JAK2 or MPL mutations
    • Pardanani A, Lasho T, Finke C, et al. LNK mutation studies in blast-phase myeloproliferative neoplasms, and in chronic-phase disease with TET2, IDH, JAK2 or MPL mutations. Leukemia 2010;24:1713-1718.
    • (2010) Leukemia , vol.24 , pp. 1713-1718
    • Pardanani, A.1    Lasho, T.2    Finke, C.3
  • 54
    • 84975286202 scopus 로고    scopus 로고
    • Rationale for revision and proposed changes of the WHO diagnostic criteria for polycythemia vera, essential thrombocythemia and primary myelofibrosis
    • Barbui T, Thiele J, Vannucchi AM, et al. Rationale for revision and proposed changes of the WHO diagnostic criteria for polycythemia vera, essential thrombocythemia and primary myelofibrosis. Blood Cancer J 2015;5:e337.
    • (2015) Blood Cancer J , vol.5 , pp. e337
    • Barbui, T.1    Thiele, J.2    Vannucchi, A.M.3
  • 55
    • 84892882972 scopus 로고    scopus 로고
    • Masked polycythemia vera (mPV): Results of an international study
    • Barbui T, Thiele J, Gisslinger H, et al. Masked polycythemia vera (mPV): Results of an international study. Am J Hematol 2014;89:52-54.
    • (2014) Am J Hematol , vol.89 , pp. 52-54
    • Barbui, T.1    Thiele, J.2    Gisslinger, H.3
  • 56
    • 84893964717 scopus 로고    scopus 로고
    • Masked polycythemia vera diagnosed according to WHO and BCSH classification
    • Barbui T, Thiele J, Carobbio A, et al. Masked polycythemia vera diagnosed according to WHO and BCSH classification. Am J Hematol 2014;89:199-202.
    • (2014) Am J Hematol , vol.89 , pp. 199-202
    • Barbui, T.1    Thiele, J.2    Carobbio, A.3
  • 57
    • 84900852237 scopus 로고    scopus 로고
    • Discriminating between essential thrombocythemia and masked polycythemia vera in JAK2 mutated patients
    • Barbui T, Thiele J, Carobbio A, et al. Discriminating between essential thrombocythemia and masked polycythemia vera in JAK2 mutated patients. Am J Hematol 2014;89:588-590.
    • (2014) Am J Hematol , vol.89 , pp. 588-590
    • Barbui, T.1    Thiele, J.2    Carobbio, A.3
  • 58
    • 74049112732 scopus 로고    scopus 로고
    • Prodromal myeloproliferative neoplasms: The 2008 WHO classification
    • Kvasnicka HM, Thiele J. Prodromal myeloproliferative neoplasms: The 2008 WHO classification. Am J Hematol 2010;85:62-69.
    • (2010) Am J Hematol , vol.85 , pp. 62-69
    • Kvasnicka, H.M.1    Thiele, J.2
  • 59
    • 84888053932 scopus 로고    scopus 로고
    • World Health Organization-defined classification of myeloproliferative neoplasms: Morphological reproducibility and clinical correlations-The Danish experience
    • Madelung AB, Bondo H, Stamp I, et al. World Health Organization-defined classification of myeloproliferative neoplasms: Morphological reproducibility and clinical correlations-The Danish experience. Am J Hematol 2013;88:1012-1016.
    • (2013) Am J Hematol , vol.88 , pp. 1012-1016
    • Madelung, A.B.1    Bondo, H.2    Stamp, I.3
  • 60
    • 39149105615 scopus 로고    scopus 로고
    • Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: A consensus statement from the International Working Group for Myelofibrosis Research and Treatment
    • Barosi G, Mesa RA, Thiele J, et al. Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: A consensus statement from the International Working Group for Myelofibrosis Research and Treatment. Leukemia 2008;22:437-438.
    • (2008) Leukemia , vol.22 , pp. 437-438
    • Barosi, G.1    Mesa, R.A.2    Thiele, J.3
  • 61
    • 84883742082 scopus 로고    scopus 로고
    • Survival and prognosis among 1545 patients with contemporary polycythemia vera: An international study
    • Tefferi A, Rumi E, Finazzi G, et al. Survival and prognosis among 1545 patients with contemporary polycythemia vera: An international study. Leukemia 2013;27:1874-1881.
    • (2013) Leukemia , vol.27 , pp. 1874-1881
    • Tefferi, A.1    Rumi, E.2    Finazzi, G.3
  • 62
    • 77956439565 scopus 로고    scopus 로고
    • A prospective study of 338 patients with polycythemia vera: The impact of JAK2 (V617F) allele burden and leukocytosis on fibrotic or leukemic disease transformation and vascular complications
    • Passamonti F, Rumi E, Pietra D, et al. A prospective study of 338 patients with polycythemia vera: The impact of JAK2 (V617F) allele burden and leukocytosis on fibrotic or leukemic disease transformation and vascular complications. Leukemia 2010;24:1574-1579.
    • (2010) Leukemia , vol.24 , pp. 1574-1579
    • Passamonti, F.1    Rumi, E.2    Pietra, D.3
  • 63
    • 84865187605 scopus 로고    scopus 로고
    • A prognostic model to predict survival in 867 World Health Organization-defined essential thrombocythemia at diagnosis: A study by the International Working Group on Myelofibrosis Research and Treatment
    • Passamonti F, Thiele J, Girodon F, et al. A prognostic model to predict survival in 867 World Health Organization-defined essential thrombocythemia at diagnosis: A study by the International Working Group on Myelofibrosis Research and Treatment. Blood 2012;120:1197-1201.
    • (2012) Blood , vol.120 , pp. 1197-1201
    • Passamonti, F.1    Thiele, J.2    Girodon, F.3
  • 64
    • 84927094466 scopus 로고    scopus 로고
    • Calreticulin mutations and long-term survival in essential thrombocythemia
    • Tefferi A, Wassie EA, Lasho TL, et al. Calreticulin mutations and long-term survival in essential thrombocythemia. Leukemia 2014;28:2300-2303.
    • (2014) Leukemia , vol.28 , pp. 2300-2303
    • Tefferi, A.1    Wassie, E.A.2    Lasho, T.L.3
  • 65
    • 80051803115 scopus 로고    scopus 로고
    • Survival and disease progression in essential thrombocythemia are significantly influenced by accurate morphologic diagnosis: An international study
    • Barbui T, Thiele J, Passamonti F, et al. Survival and disease progression in essential thrombocythemia are significantly influenced by accurate morphologic diagnosis: An international study. J Clin Oncol Off J Am Soc Clin Oncol 2011;29:3179-3184.
    • (2011) J Clin Oncol Off J Am Soc Clin Oncol , vol.29 , pp. 3179-3184
    • Barbui, T.1    Thiele, J.2    Passamonti, F.3
  • 66
    • 63849328927 scopus 로고    scopus 로고
    • New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for myelofibrosis research and treatment
    • Cervantes F, Dupriez B, Pereira A, et al. New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for myelofibrosis research and treatment. Blood 2009;113:2895-2901.
    • (2009) Blood , vol.113 , pp. 2895-2901
    • Cervantes, F.1    Dupriez, B.2    Pereira, A.3
  • 67
    • 77950352432 scopus 로고    scopus 로고
    • A dynamic prognostic model to predict survival in primary myelofibrosis: A study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment)
    • Passamonti F, Cervantes F, Vannucchi AM, et al. A dynamic prognostic model to predict survival in primary myelofibrosis: A study by the IWG-MRT (International Working Group for Myeloproliferative Neoplasms Research and Treatment). Blood 2010;115:1703-1708.
    • (2010) Blood , vol.115 , pp. 1703-1708
    • Passamonti, F.1    Cervantes, F.2    Vannucchi, A.M.3
  • 68
    • 79952087335 scopus 로고    scopus 로고
    • DIPSS plus: A refined Dynamic International Prognostic Scoring System for primary myelofibrosis that incorporates prognostic information from karyotype, platelet count, and transfusion status
    • Gangat N, Caramazza D, Vaidya R, et al. DIPSS plus: A refined Dynamic International Prognostic Scoring System for primary myelofibrosis that incorporates prognostic information from karyotype, platelet count, and transfusion status. J Clin Oncol 2011;29:392-397.
    • (2011) J Clin Oncol , vol.29 , pp. 392-397
    • Gangat, N.1    Caramazza, D.2    Vaidya, R.3
  • 69
    • 77449126735 scopus 로고    scopus 로고
    • International prognostic scoring system-independent cytogenetic risk categorization in primary myelofibrosis
    • Hussein K, Pardanani AD, Van Dyke DL, et al. International prognostic scoring system-independent cytogenetic risk categorization in primary myelofibrosis. Blood 2010;115:496-499.
    • (2010) Blood , vol.115 , pp. 496-499
    • Hussein, K.1    Pardanani, A.D.2    Van Dyke, D.L.3
  • 70
    • 78651344350 scopus 로고    scopus 로고
    • Refined cytogenetic-risk categorization for overall and leukemia-free survival in primary myelofibrosis: A single center study of 433 patients
    • Caramazza D, Begna KH, Gangat N, et al. Refined cytogenetic-risk categorization for overall and leukemia-free survival in primary myelofibrosis: A single center study of 433 patients. Leukemia 2011;25:82-88.
    • (2011) Leukemia , vol.25 , pp. 82-88
    • Caramazza, D.1    Begna, K.H.2    Gangat, N.3
  • 71
    • 74049158614 scopus 로고    scopus 로고
    • Transfusion-dependency at presentation and its acquisition in the first year of diagnosis are both equally detrimental for survival in primary myelofibrosis-prognostic relevance is independent of IPSS or karyotype
    • Tefferi A, Siragusa S, Hussein K, et al. Transfusion-dependency at presentation and its acquisition in the first year of diagnosis are both equally detrimental for survival in primary myelofibrosis-prognostic relevance is independent of IPSS or karyotype. Am J Hematol 2009;85:14-17.
    • (2009) Am J Hematol , vol.85 , pp. 14-17
    • Tefferi, A.1    Siragusa, S.2    Hussein, K.3
  • 72
    • 78650989990 scopus 로고    scopus 로고
    • Red blood cell transfusion-dependency implies a poor survival in primary myelofibrosis irrespective of international prognostic scoring system and dynamic international prognostic scoring system
    • Elena C, Passamonti F, Rumi E, et al. Red blood cell transfusion-dependency implies a poor survival in primary myelofibrosis irrespective of international prognostic scoring system and dynamic international prognostic scoring system. Haematologica 2011;96:167-170.
    • (2011) Haematologica , vol.96 , pp. 167-170
    • Elena, C.1    Passamonti, F.2    Rumi, E.3
  • 73
    • 74049116496 scopus 로고    scopus 로고
    • Age and platelet count are IPSS-independent prognostic factors in young patients with primary myelofibrosis and complement IPSS in predicting very long or very short survival
    • Patnaik MM, Caramazza D, Gangat N, et al. Age and platelet count are IPSS-independent prognostic factors in young patients with primary myelofibrosis and complement IPSS in predicting very long or very short survival. Eur J Haematol 2010;84:105-108.
    • (2010) Eur J Haematol , vol.84 , pp. 105-108
    • Patnaik, M.M.1    Caramazza, D.2    Gangat, N.3
  • 74
    • 79957625402 scopus 로고    scopus 로고
    • Monosomal karyotype in primary myelofibrosis is detrimental to both overall and leukemia-free survival
    • Vaidya R, Caramazza D, Begna KH, et al. Monosomal karyotype in primary myelofibrosis is detrimental to both overall and leukemia-free survival. Blood 2011;117:5612-5615.
    • (2011) Blood , vol.117 , pp. 5612-5615
    • Vaidya, R.1    Caramazza, D.2    Begna, K.H.3
  • 75
    • 74249123815 scopus 로고    scopus 로고
    • JAK2 germline genetic variation affects disease susceptibility in primary myelofibrosis regardless of V617F mutational status: Nullizygosity for the JAK2 46/1 haplotype is associated with inferior survival
    • Tefferi A, Lasho TL, Patnaik MM, et al. JAK2 germline genetic variation affects disease susceptibility in primary myelofibrosis regardless of V617F mutational status: Nullizygosity for the JAK2 46/1 haplotype is associated with inferior survival. Leukemia 2010;24:105-109.
    • (2010) Leukemia , vol.24 , pp. 105-109
    • Tefferi, A.1    Lasho, T.L.2    Patnaik, M.M.3
  • 76
    • 42449124578 scopus 로고    scopus 로고
    • Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival
    • Tefferi A, Lasho TL, Huang J, et al. Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival. Leukemia 2008;22:756-761.
    • (2008) Leukemia , vol.22 , pp. 756-761
    • Tefferi, A.1    Lasho, T.L.2    Huang, J.3
  • 77
    • 70349580685 scopus 로고    scopus 로고
    • Identification of patients with poorer survival in primary myelofibrosis based on the burden of JAK2V617F mutated allele
    • Guglielmelli P, Barosi G, Specchia G, et al. Identification of patients with poorer survival in primary myelofibrosis based on the burden of JAK2V617F mutated allele. Blood 2009;114:1477-1483.
    • (2009) Blood , vol.114 , pp. 1477-1483
    • Guglielmelli, P.1    Barosi, G.2    Specchia, G.3
  • 78
    • 84908275738 scopus 로고    scopus 로고
    • The number of prognostically detrimental mutations and prognosis in primary myelofibrosis: An international study of 797 patients
    • Guglielmelli P, Lasho TL, Rotunno G, et al. The number of prognostically detrimental mutations and prognosis in primary myelofibrosis: An international study of 797 patients. Leukemia 2014;28:1804-1810.
    • (2014) Leukemia , vol.28 , pp. 1804-1810
    • Guglielmelli, P.1    Lasho, T.L.2    Rotunno, G.3
  • 79
    • 79954433836 scopus 로고    scopus 로고
    • Circulating interleukin (IL)-8, IL-2R, IL-12, and IL-15 levels are independently prognostic in primary myelofibrosis: A comprehensive cytokine profiling study
    • Tefferi A, Vaidya R, Caramazza D, et al. Circulating interleukin (IL)-8, IL-2R, IL-12, and IL-15 levels are independently prognostic in primary myelofibrosis: A comprehensive cytokine profiling study. J Clin Oncol Off J Am Soc Clin Oncol 2011;29:1356-1363.
    • (2011) J Clin Oncol Off J Am Soc Clin Oncol , vol.29 , pp. 1356-1363
    • Tefferi, A.1    Vaidya, R.2    Caramazza, D.3
  • 80
    • 84863462122 scopus 로고    scopus 로고
    • Polyclonal immunoglobulin free light chain levels predict survival in myeloid neoplasms
    • Pardanani A, Lasho TL, Finke CM, et al. Polyclonal immunoglobulin free light chain levels predict survival in myeloid neoplasms. J Clin Oncol Off J Am Soc Clin Oncol 2012;30:1087-1094.
    • (2012) J Clin Oncol Off J Am Soc Clin Oncol , vol.30 , pp. 1087-1094
    • Pardanani, A.1    Lasho, T.L.2    Finke, C.M.3
  • 81
    • 84904056081 scopus 로고    scopus 로고
    • CALR and ASXL1 mutations-based molecular prognostication in primary myelofibrosis: An international study of 570 patients
    • Tefferi A, Guglielmelli P, Lasho TL, et al. CALR and ASXL1 mutations-based molecular prognostication in primary myelofibrosis: An international study of 570 patients. Leukemia 2014;28:1494-1500.
    • (2014) Leukemia , vol.28 , pp. 1494-1500
    • Tefferi, A.1    Guglielmelli, P.2    Lasho, T.L.3
  • 82
    • 0022743379 scopus 로고
    • Polycythemia Vera Study Group: A historical perspective
    • Wasserman LR. Polycythemia Vera Study Group: A historical perspective. Semin Hematol 1986;23:183-187.
    • (1986) Semin Hematol , vol.23 , pp. 183-187
    • Wasserman, L.R.1
  • 83
    • 0346727336 scopus 로고    scopus 로고
    • Efficacy and safety of low-dose aspirin in polycythemia vera
    • Landolfi R, Marchioli R, Kutti J, et al. Efficacy and safety of low-dose aspirin in polycythemia vera. N Engl J Med 2004;50:114-124.
    • (2004) N Engl J Med , vol.50 , pp. 114-124
    • Landolfi, R.1    Marchioli, R.2    Kutti, J.3
  • 84
    • 84871746842 scopus 로고    scopus 로고
    • Cardiovascular events and intensity of treatment in polycythemia vera
    • Marchioli R, Finazzi G, Specchia G, et al. Cardiovascular events and intensity of treatment in polycythemia vera. N Engl J Med 2013;368:22-33.
    • (2013) N Engl J Med , vol.368 , pp. 22-33
    • Marchioli, R.1    Finazzi, G.2    Specchia, G.3
  • 85
    • 0028913012 scopus 로고
    • Hydroxyurea for patients with essential thrombocythemia and a high risk of thrombosis
    • Cortelazzo S, Finazzi G, Ruggeri M, et al. Hydroxyurea for patients with essential thrombocythemia and a high risk of thrombosis. N Engl J Med 1995;332:1132-1136.
    • (1995) N Engl J Med , vol.332 , pp. 1132-1136
    • Cortelazzo, S.1    Finazzi, G.2    Ruggeri, M.3
  • 86
    • 0141498524 scopus 로고
    • Ein betrag zur kentniss der symptmologie und therapie der primaren polycythemie
    • Ludin M. Ein betrag zur kentniss der symptmologie und therapie der primaren polycythemie. Z Klin Med 1917;84:460-476.
    • (1917) Z Klin Med , vol.84 , pp. 460-476
    • Ludin, M.1
  • 87
    • 0141721936 scopus 로고
    • Zur Therapie der Polyzythaemie
    • Eppinger H, Kloss K. Zur Therapie der Polyzythaemie. Therap Monatshefte 1918;32:322-326.
    • (1918) Therap Monatshefte , vol.32 , pp. 322-326
    • Eppinger, H.1    Kloss, K.2
  • 88
    • 38349055824 scopus 로고
    • Treatment of polycythemia vera (erythremia) with a solution of potassium arsenite
    • Forkner CE, Scott TFM, Wu SC. Treatment of polycythemia vera (erythremia) with a solution of potassium arsenite. Arch Intern Med 1933;51:616-629.
    • (1933) Arch Intern Med , vol.51 , pp. 616-629
    • Forkner, C.E.1    Scott, T.F.M.2    Wu, S.C.3
  • 89
    • 0001793805 scopus 로고
    • Nuclear physics and therapy: Preliminary report on a new method for the treatment of leukemia and polycythemia vera
    • Lawrence JH. Nuclear physics and therapy: Preliminary report on a new method for the treatment of leukemia and polycythemia vera. Radiology 1940;35:51-60.
    • (1940) Radiology , vol.35 , pp. 51-60
    • Lawrence, J.H.1
  • 90
    • 38349005651 scopus 로고
    • The treatment of polycythemia vera with lead compunds
    • Falconer EH. The treatment of polycythemia vera with lead compunds. Am J Med 1942;203:856-857.
    • (1942) Am J Med , vol.203 , pp. 856-857
    • Falconer, E.H.1
  • 91
    • 38349007689 scopus 로고
    • Effects of nitrogen mustard on the bone marrow in polycythemia vera
    • Shullenberger CC, Watkins CH. Effects of nitrogen mustard on the bone marrow in polycythemia vera. Ann Intern Med 1950;33:841-853.
    • (1950) Ann Intern Med , vol.33 , pp. 841-853
    • Shullenberger, C.C.1    Watkins, C.H.2
  • 92
    • 38349004040 scopus 로고
    • Treatment of polycythemia vera with triethylene melamine: Summary of thirtty cases
    • Rosenthal N, Rosenthal RL. Treatment of polycythemia vera with triethylene melamine: Summary of thirtty cases. Arch Intern Med 1952;90:379.
    • (1952) Arch Intern Med , vol.90 , pp. 379
    • Rosenthal, N.1    Rosenthal, R.L.2
  • 93
    • 38349046192 scopus 로고
    • Treatment of polycythemia vera with daraprim
    • Isaacs R. Treatment of polycythemia vera with daraprim. J Am Med Assoc 1954;156:1491-1493.
    • (1954) J Am Med Assoc , vol.156 , pp. 1491-1493
    • Isaacs, R.1
  • 94
    • 38349017698 scopus 로고
    • Therapy of polycythemia vera with myleran
    • Wald N, Hoshino T, Sears ME. Therapy of polycythemia vera with myleran. Blood 1958;13:757-762.
    • (1958) Blood , vol.13 , pp. 757-762
    • Wald, N.1    Hoshino, T.2    Sears, M.E.3
  • 95
    • 38349001968 scopus 로고
    • Long-range treatment of polycythemia vera with 6-mercaptopurine
    • Shullenberger CC. Long-range treatment of polycythemia vera with 6-mercaptopurine. Cancer Chemother Rep 1962;16:251-252.
    • (1962) Cancer Chemother Rep , vol.16 , pp. 251-252
    • Shullenberger, C.C.1
  • 96
    • 4243546143 scopus 로고
    • Evaluation of compund 8103 Abbott (N,N' bis (bromopropionyl) piperazine) in the treatment of polycythemia rubra vera
    • Bond WH. Evaluation of compund 8103 Abbott (N, N' bis (bromopropionyl) piperazine) in the treatment of polycythemia rubra vera. Proc Am Assoc Cancer Res 1962;3:306.
    • (1962) Proc Am Assoc Cancer Res , vol.3 , pp. 306
    • Bond, W.H.1
  • 97
    • 76549142347 scopus 로고
    • Polycythaemia Vera: Clinical studies on a series of 127 patients managed without radiation therapy
    • Perkins J, Israuels MC, Wilkinson JF. Polycythaemia Vera: Clinical studies on a series of 127 patients managed without radiation therapy. Q J Med 1964;33:499-518.
    • (1964) Q J Med , vol.33 , pp. 499-518
    • Perkins, J.1    Israuels, M.C.2    Wilkinson, J.F.3
  • 98
    • 0013796845 scopus 로고
    • Evaluation of haemopoiesis and comparative study of 32P and chlorambucil therapy by means of radiotracers in polycythemia vera
    • Varela JE, Kremenchuzky S, Fraga A, et al. Evaluation of haemopoiesis and comparative study of 32P and chlorambucil therapy by means of radiotracers in polycythemia vera. Miner Nucl 1965;9:275-280.
    • (1965) Miner Nucl , vol.9 , pp. 275-280
    • Varela, J.E.1    Kremenchuzky, S.2    Fraga, A.3
  • 99
    • 0014026875 scopus 로고
    • Reduction of haematocrit and red-blood-cell volume in patients with polycythaemia secondary to hypoxic lung disease by dapsone and pyrimethamine
    • Pengelly CD. Reduction of haematocrit and red-blood-cell volume in patients with polycythaemia secondary to hypoxic lung disease by dapsone and pyrimethamine. Lancet 1966;2:1381-1386.
    • (1966) Lancet , vol.2 , pp. 1381-1386
    • Pengelly, C.D.1
  • 100
    • 38349043185 scopus 로고
    • Response of polycythemia to treatment with a new agent: Hydroxyurea (abstract)
    • West WO, Ruff JD, Yarboro JW. Response of polycythemia to treatment with a new agent: Hydroxyurea (abstract). Ann Intern Med 1970;72:795.
    • (1970) Ann Intern Med , vol.72 , pp. 795
    • West, W.O.1    Ruff, J.D.2    Yarboro, J.W.3
  • 101
    • 0014820049 scopus 로고
    • Melphalan therapy of polycythemia vera
    • Logue GL, Gutterman JU, McGinn TG, et al. Melphalan therapy of polycythemia vera. Blood 1970;36:70-86.
    • (1970) Blood , vol.36 , pp. 70-86
    • Logue, G.L.1    Gutterman, J.U.2    McGinn, T.G.3
  • 102
    • 0141610274 scopus 로고
    • Chronic cyanotic polycythemia with enlarged spleen
    • Osler W. Chronic cyanotic polycythemia with enlarged spleen. Br Med J 1904;1.
    • (1904) Br Med J , vol.1
    • Osler, W.1
  • 103
    • 0001148171 scopus 로고
    • Complications and causes of death in polycythemia vera
    • Chievitz E, Thiede T. Complications and causes of death in polycythemia vera. Acta Med Scand 1962;172:513-523.
    • (1962) Acta Med Scand , vol.172 , pp. 513-523
    • Chievitz, E.1    Thiede, T.2
  • 104
    • 0002596838 scopus 로고
    • Treatment of polycythemia vera: A summary of clinical trials conducted by the polycythemia vera study group
    • In: Wasserman LR, Berk PD, Berlin NI, editors.Philadelphia: W.B. Saunders;
    • Berk PD, Wasserman LR, Fruchtman SM, et al. Treatment of polycythemia vera: A summary of clinical trials conducted by the polycythemia vera study group. In: Wasserman LR, Berk PD, Berlin NI, editors. Polycythemia Vera and the Myeloproliferative Disorders. Philadelphia: W.B. Saunders; 1995. pp 166-194.
    • (1995) Polycythemia Vera and the Myeloproliferative Disorders , pp. 166-194
    • Berk, P.D.1    Wasserman, L.R.2    Fruchtman, S.M.3
  • 105
    • 0031041044 scopus 로고    scopus 로고
    • From efficacy to safety-A polycythemia vera study group report on hydroxyurea in patients with polycythemia vera
    • Fruchtman SM, Mack K, Kaplan ME, et al. From efficacy to safety-A polycythemia vera study group report on hydroxyurea in patients with polycythemia vera. Semin Hematol 1997;34:17-23.
    • (1997) Semin Hematol , vol.34 , pp. 17-23
    • Fruchtman, S.M.1    Mack, K.2    Kaplan, M.E.3
  • 106
    • 84989775088 scopus 로고    scopus 로고
    • Myeloproliferative neoplasms: A contemporary review
    • Tefferi A, Pardanani A. Myeloproliferative neoplasms: A contemporary review. JAMA Oncol 2015;1:97-105.
    • (2015) JAMA Oncol , vol.1 , pp. 97-105
    • Tefferi, A.1    Pardanani, A.2
  • 107
    • 84946496578 scopus 로고    scopus 로고
    • Indication and management of allogeneic stem cell transplantation in primary myelofibrosis: A consensus process by an EBMT/ELN international working group
    • Kroger NM, Deeg JH, Olavarria E, et al. Indication and management of allogeneic stem cell transplantation in primary myelofibrosis: A consensus process by an EBMT/ELN international working group. Leukemia 2015.
    • (2015) Leukemia
    • Kroger, N.M.1    Deeg, J.H.2    Olavarria, E.3
  • 108
    • 84954273093 scopus 로고    scopus 로고
    • Revision of IPSET thrombosis
    • Barbui Tea, in press
    • Barbui Tea. Revision of IPSET thrombosis. Blood Cancer J, in press.
    • Blood Cancer J
  • 109
    • 84909595184 scopus 로고    scopus 로고
    • In contemporary patients with polycythemia vera, rates of thrombosis and risk factors delineate a new clinical epidemiology
    • Barbui T, Carobbio A, Rumi E, et al. In contemporary patients with polycythemia vera, rates of thrombosis and risk factors delineate a new clinical epidemiology. Blood 2014;124:3021-3023.
    • (2014) Blood , vol.124 , pp. 3021-3023
    • Barbui, T.1    Carobbio, A.2    Rumi, E.3
  • 110
    • 84655162752 scopus 로고    scopus 로고
    • Twice daily aspirin to improve biological aspirin efficacy in patients with essential thrombocythemia
    • Dillinger JG, Sideris G, Henry P, et al. Twice daily aspirin to improve biological aspirin efficacy in patients with essential thrombocythemia. Thromb Res 2012;129:91-94.
    • (2012) Thromb Res , vol.129 , pp. 91-94
    • Dillinger, J.G.1    Sideris, G.2    Henry, P.3
  • 111
    • 34249949626 scopus 로고    scopus 로고
    • Thrombosis in myeloproliferative disorders: Prevalence, prognostic factors, and the role of leukocytes and JAK2V617F
    • Tefferi A, Elliott M. Thrombosis in myeloproliferative disorders: Prevalence, prognostic factors, and the role of leukocytes and JAK2V617F. Semin Thromb Hemostasis 2007;33:313-320.
    • (2007) Semin Thromb Hemostasis , vol.33 , pp. 313-320
    • Tefferi, A.1    Elliott, M.2
  • 112
    • 84921409486 scopus 로고    scopus 로고
    • Polycythemia vera and essential thrombocythemia: 2015 update on diagnosis, risk-stratification and management
    • Tefferi A, Barbui T. Polycythemia vera and essential thrombocythemia: 2015 update on diagnosis, risk-stratification and management. Am J Hematol 2015;90:162-173.
    • (2015) Am J Hematol , vol.90 , pp. 162-173
    • Tefferi, A.1    Barbui, T.2
  • 113
    • 0022703490 scopus 로고
    • Therapeutic recommendations in polycythemia vera based on polycythemia vera study group protocols
    • Berk PD, Goldberg JD, Donovan PB, et al. Therapeutic recommendations in polycythemia vera based on polycythemia vera study group protocols. Semin Hematol 1986;23:132-143.
    • (1986) Semin Hematol , vol.23 , pp. 132-143
    • Berk, P.D.1    Goldberg, J.D.2    Donovan, P.B.3
  • 114
    • 80053945428 scopus 로고    scopus 로고
    • Treatment of polycythemia vera with hydroxyurea and pipobroman: Final results of a randomized trial initiated in 1980
    • Kiladjian JJ, Chevret S, Dosquet C, et al. Treatment of polycythemia vera with hydroxyurea and pipobroman: Final results of a randomized trial initiated in 1980. J Clin Oncol 2011;29:3907-3913.
    • (2011) J Clin Oncol , vol.29 , pp. 3907-3913
    • Kiladjian, J.J.1    Chevret, S.2    Dosquet, C.3
  • 115
    • 21444434751 scopus 로고    scopus 로고
    • Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia
    • Harrison CN, Campbell PJ, Buck G, et al. Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia. N Engl J Med 2005;353:33-45.
    • (2005) N Engl J Med , vol.353 , pp. 33-45
    • Harrison, C.N.1    Campbell, P.J.2    Buck, G.3
  • 116
    • 84922264206 scopus 로고    scopus 로고
    • Busulfan in patients with polycythemia vera or essential thrombocythemia refractory or intolerant to hydroxyurea
    • Alvarez-Larran A, Martinez-Aviles L, Hernandez-Boluda JC, et al. Busulfan in patients with polycythemia vera or essential thrombocythemia refractory or intolerant to hydroxyurea. Ann Hematol 2014;93:2037-2043.
    • (2014) Ann Hematol , vol.93 , pp. 2037-2043
    • Alvarez-Larran, A.1    Martinez-Aviles, L.2    Hernandez-Boluda, J.C.3
  • 117
    • 33746307253 scopus 로고    scopus 로고
    • Long-term effects of the treatment of polycythemia vera with recombinant interferon-alpha
    • Silver RT. Long-term effects of the treatment of polycythemia vera with recombinant interferon-alpha. Cancer 2006;107:451-458.
    • (2006) Cancer , vol.107 , pp. 451-458
    • Silver, R.T.1
  • 118
    • 84903879916 scopus 로고    scopus 로고
    • Interferon alfa therapy in CALR-mutated essential thrombocythemia
    • Cassinat B, Verger E, Kiladjian JJ. Interferon alfa therapy in CALR-mutated essential thrombocythemia. N Engl J Med 2014;371:188-189.
    • (2014) N Engl J Med , vol.371 , pp. 188-189
    • Cassinat, B.1    Verger, E.2    Kiladjian, J.J.3
  • 119
    • 54049141336 scopus 로고    scopus 로고
    • Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera
    • Kiladjian JJ, Cassinat B, Chevret S, et al. Pegylated interferon-alfa-2a induces complete hematologic and molecular responses with low toxicity in polycythemia vera. Blood 2008;112:3065-3072.
    • (2008) Blood , vol.112 , pp. 3065-3072
    • Kiladjian, J.J.1    Cassinat, B.2    Chevret, S.3
  • 120
    • 84887008308 scopus 로고    scopus 로고
    • JAK2V617F allele burden is reduced by busulfan therapy: A new observation using an old drug
    • Kuriakose ET, Gjoni S, Wang YL, et al. JAK2V617F allele burden is reduced by busulfan therapy: A new observation using an old drug. Haematologica 2013;98:e135-e137.
    • (2013) Haematologica , vol.98 , pp. e135-e137
    • Kuriakose, E.T.1    Gjoni, S.2    Wang, Y.L.3
  • 121
    • 84921891315 scopus 로고    scopus 로고
    • Ruxolitinib versus standard therapy for the treatment of polycythemia vera
    • Vannucchi AM, Kiladjian JJ, Griesshammer M, et al. Ruxolitinib versus standard therapy for the treatment of polycythemia vera. N Engl J Med 2015;372:426-435.
    • (2015) N Engl J Med , vol.372 , pp. 426-435
    • Vannucchi, A.M.1    Kiladjian, J.J.2    Griesshammer, M.3
  • 122
    • 84892882122 scopus 로고    scopus 로고
    • Ruxolitinib is a potent immunosuppressive compound: Is it time for anti-infective prophylaxis?
    • Heine A, Brossart P, Wolf D. Ruxolitinib is a potent immunosuppressive compound: Is it time for anti-infective prophylaxis? Blood 2013;122:3843-3844.
    • (2013) Blood , vol.122 , pp. 3843-3844
    • Heine, A.1    Brossart, P.2    Wolf, D.3
  • 123
    • 84858855487 scopus 로고    scopus 로고
    • JAK inhibitors for myeloproliferative neoplasms: Clarifying facts from myths
    • Tefferi A. JAK inhibitors for myeloproliferative neoplasms: Clarifying facts from myths. Blood 2012;119:2721-2730.
    • (2012) Blood , vol.119 , pp. 2721-2730
    • Tefferi, A.1
  • 125
    • 78549245112 scopus 로고    scopus 로고
    • Efficacy and tolerability of hydroxyurea in the treatment of the hyperproliferative manifestations of myelofibrosis: Results in 40 patients
    • Martinez-Trillos A, Gaya A, Maffioli M, et al. Efficacy and tolerability of hydroxyurea in the treatment of the hyperproliferative manifestations of myelofibrosis: Results in 40 patients. Ann Hematol 2010;89:1233-1237.
    • (2010) Ann Hematol , vol.89 , pp. 1233-1237
    • Martinez-Trillos, A.1    Gaya, A.2    Maffioli, M.3
  • 127
    • 39749167036 scopus 로고    scopus 로고
    • New and old treatment modalities in primary myelofibrosis
    • Cervantes F, Mesa R, Barosi G. New and old treatment modalities in primary myelofibrosis. Cancer J 2007;13:377-383.
    • (2007) Cancer J , vol.13 , pp. 377-383
    • Cervantes, F.1    Mesa, R.2    Barosi, G.3
  • 128
    • 0036243117 scopus 로고    scopus 로고
    • Thalidomide treatment in myelofibrosis with myeloid metaplasia
    • Elliott MA, Mesa RA, Li CY, et al. Thalidomide treatment in myelofibrosis with myeloid metaplasia. Br J Haematol 2002;117:288-296.
    • (2002) Br J Haematol , vol.117 , pp. 288-296
    • Elliott, M.A.1    Mesa, R.A.2    Li, C.Y.3
  • 129
    • 33646336631 scopus 로고    scopus 로고
    • Thalidomide therapy for myelofibrosis with myeloid metaplasia
    • Thomas DA, Giles FJ, Albitar M, et al. Thalidomide therapy for myelofibrosis with myeloid metaplasia. Cancer 2006;106:1974-1984.
    • (2006) Cancer , vol.106 , pp. 1974-1984
    • Thomas, D.A.1    Giles, F.J.2    Albitar, M.3
  • 130
    • 0012889254 scopus 로고    scopus 로고
    • A phase 2 trial of combination low-dose thalidomide and prednisone for the treatment of myelofibrosis with myeloid metaplasia
    • Mesa RA, Steensma DP, Pardanani A, et al. A phase 2 trial of combination low-dose thalidomide and prednisone for the treatment of myelofibrosis with myeloid metaplasia. Blood 2003;101:2534-2541.
    • (2003) Blood , vol.101 , pp. 2534-2541
    • Mesa, R.A.1    Steensma, D.P.2    Pardanani, A.3
  • 131
    • 33747167338 scopus 로고    scopus 로고
    • Lenalidomide therapy in myelofibrosis with myeloid metaplasia
    • Tefferi A, Cortes J, Verstovsek S, et al. Lenalidomide therapy in myelofibrosis with myeloid metaplasia. Blood 2006;108:1158-1164.
    • (2006) Blood , vol.108 , pp. 1158-1164
    • Tefferi, A.1    Cortes, J.2    Verstovsek, S.3
  • 132
    • 70350439432 scopus 로고    scopus 로고
    • Lenalidomide plus prednisone results in durable clinical, histopathologic, and molecular responses in patients with myelofibrosis
    • Quintas-Cardama A, Kantarjian HM, Manshouri T, et al. Lenalidomide plus prednisone results in durable clinical, histopathologic, and molecular responses in patients with myelofibrosis. J Clin Oncol 2009;27:4760-4766.
    • (2009) J Clin Oncol , vol.27 , pp. 4760-4766
    • Quintas-Cardama, A.1    Kantarjian, H.M.2    Manshouri, T.3
  • 133
    • 84906053853 scopus 로고    scopus 로고
    • Primary myelofibrosis: 2014 update on diagnosis, risk-stratification, and management
    • Tefferi A. Primary myelofibrosis: 2014 update on diagnosis, risk-stratification, and management. Am J Hematol 2014;89:915-925.
    • (2014) Am J Hematol , vol.89 , pp. 915-925
    • Tefferi, A.1
  • 134
    • 71949121402 scopus 로고    scopus 로고
    • Pomalidomide is active in the treatment of anemia associated with myelofibrosis
    • Tefferi A, Verstovsek S, Barosi G, et al. Pomalidomide is active in the treatment of anemia associated with myelofibrosis. J Clin Oncol 2009;27:4563-4569.
    • (2009) J Clin Oncol , vol.27 , pp. 4563-4569
    • Tefferi, A.1    Verstovsek, S.2    Barosi, G.3
  • 135
    • 84155169034 scopus 로고    scopus 로고
    • Long-term outcome of pomalidomide therapy in myelofibrosis
    • Begna KH, Pardanani A, Mesa R, et al. Long-term outcome of pomalidomide therapy in myelofibrosis. Am J Hematol 2012;87:66-68.
    • (2012) Am J Hematol , vol.87 , pp. 66-68
    • Begna, K.H.1    Pardanani, A.2    Mesa, R.3
  • 136
    • 79751528798 scopus 로고    scopus 로고
    • A phase-2 trial of low-dose pomalidomide in myelofibrosis
    • Begna KH, Mesa RA, Pardanani A, et al. A phase-2 trial of low-dose pomalidomide in myelofibrosis. Leukemia 2011;25:301-304.
    • (2011) Leukemia , vol.25 , pp. 301-304
    • Begna, K.H.1    Mesa, R.A.2    Pardanani, A.3
  • 137
    • 84896968737 scopus 로고    scopus 로고
    • Phase 3 study of pomalidomide in myeloproliferative neoplasm (MPN)-associated myelofibrosis with RBC-transfusion-dependence
    • Tefferi A, Passamonti F, Barbui T, et al. Phase 3 study of pomalidomide in myeloproliferative neoplasm (MPN)-associated myelofibrosis with RBC-transfusion-dependence. Blood 2013;122.
    • (2013) Blood , vol.122
    • Tefferi, A.1    Passamonti, F.2    Barbui, T.3
  • 138
    • 84863393110 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis
    • Verstovsek S, Mesa RA, Gotlib J, et al. A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis. N Engl J Med 2012;366:799-807.
    • (2012) N Engl J Med , vol.366 , pp. 799-807
    • Verstovsek, S.1    Mesa, R.A.2    Gotlib, J.3
  • 139
    • 84857837774 scopus 로고    scopus 로고
    • JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis
    • Harrison C, Kiladjian JJ, Al-Ali HK, et al. JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis. N Engl J Med 2012;366:787-798.
    • (2012) N Engl J Med , vol.366 , pp. 787-798
    • Harrison, C.1    Kiladjian, J.J.2    Al-Ali, H.K.3
  • 140
    • 80054028202 scopus 로고    scopus 로고
    • Long-term outcome of treatment with ruxolitinib in myelofibrosis
    • Tefferi A, Litzow MR, Pardanani A. Long-term outcome of treatment with ruxolitinib in myelofibrosis. N Engl J Med 2011;365:1455-1457.
    • (2011) N Engl J Med , vol.365 , pp. 1455-1457
    • Tefferi, A.1    Litzow, M.R.2    Pardanani, A.3
  • 141
    • 84891303523 scopus 로고    scopus 로고
    • Three-year efficacy, safety, and survival findings from COMFORT-II, a phase 3 study comparing ruxolitinib with best available therapy for myelofibrosis
    • Cervantes F, Vannucchi AM, Kiladjian JJ, et al. Three-year efficacy, safety, and survival findings from COMFORT-II, a phase 3 study comparing ruxolitinib with best available therapy for myelofibrosis. Blood 2013;122:4047-4053.
    • (2013) Blood , vol.122 , pp. 4047-4053
    • Cervantes, F.1    Vannucchi, A.M.2    Kiladjian, J.J.3
  • 142
    • 84964694744 scopus 로고    scopus 로고
    • Safety and efficacy of fedratinib in patients with primary or secondary myelofibrosis: A randomized clinical trial
    • Pardanani A, Harrison C, Cortes JE, et al. Safety and efficacy of fedratinib in patients with primary or secondary myelofibrosis: A randomized clinical trial. JAMA Oncol 2015;1:643-651.
    • (2015) JAMA Oncol , vol.1 , pp. 643-651
    • Pardanani, A.1    Harrison, C.2    Cortes, J.E.3
  • 143
    • 84975231524 scopus 로고    scopus 로고
    • A phase 2 randomized dose-ranging study of the JAK2-selective inhibitor fedratinib (SAR302503) in patients with myelofibrosis
    • Pardanani A, Tefferi A, Jamieson C, et al. A phase 2 randomized dose-ranging study of the JAK2-selective inhibitor fedratinib (SAR302503) in patients with myelofibrosis. Blood Cancer J 2015;5:e335.
    • (2015) Blood Cancer J , vol.5 , pp. e335
    • Pardanani, A.1    Tefferi, A.2    Jamieson, C.3
  • 144
    • 84924965031 scopus 로고    scopus 로고
    • Momelotinib treatment-emergent neuropathy: Prevalence, risk factors and outcome in 100 patients with myelofibrosis
    • Abdelrahman RA, Begna KH, Al-Kali A, et al. Momelotinib treatment-emergent neuropathy: Prevalence, risk factors and outcome in 100 patients with myelofibrosis. Br J Haematol 2015;169:77-80.
    • (2015) Br J Haematol , vol.169 , pp. 77-80
    • Abdelrahman, R.A.1    Begna, K.H.2    Al-Kali, A.3
  • 145
    • 84924585836 scopus 로고    scopus 로고
    • Genetic determinants of response and survival in momelotinib-treated patients with myelofibrosis
    • Pardanani A, Abdelrahman RA, Finke C, et al. Genetic determinants of response and survival in momelotinib-treated patients with myelofibrosis. Leukemia 2015;29:741-744.
    • (2015) Leukemia , vol.29 , pp. 741-744
    • Pardanani, A.1    Abdelrahman, R.A.2    Finke, C.3
  • 146
    • 84922465797 scopus 로고    scopus 로고
    • Revised assessment of response and long-term discontinuation rates among 111 patients with myelofibrosis treated with momelotinib or ruxolitinib
    • Abdelrahman RA, Begna KH, Al-Kali A, et al. Revised assessment of response and long-term discontinuation rates among 111 patients with myelofibrosis treated with momelotinib or ruxolitinib. Leukemia 2015;29:498-500.
    • (2015) Leukemia , vol.29 , pp. 498-500
    • Abdelrahman, R.A.1    Begna, K.H.2    Al-Kali, A.3
  • 147
    • 84878951826 scopus 로고    scopus 로고
    • Safety and efficacy of CYT387, a JAK1 and JAK2 inhibitor, in myelofibrosis
    • Pardanani A, Laborde RR, Lasho TL, et al. Safety and efficacy of CYT387, a JAK1 and JAK2 inhibitor, in myelofibrosis. Leukemia 2013;27:1322-1327.
    • (2013) Leukemia , vol.27 , pp. 1322-1327
    • Pardanani, A.1    Laborde, R.R.2    Lasho, T.L.3
  • 148
    • 68749084623 scopus 로고    scopus 로고
    • CYT387, a selective JAK1/JAK2 inhibitor: In vitro assessment of kinase selectivity and preclinical studies using cell lines and primary cells from polycythemia vera patients
    • Pardanani A, Lasho T, Smith G, et al. CYT387, a selective JAK1/JAK2 inhibitor: In vitro assessment of kinase selectivity and preclinical studies using cell lines and primary cells from polycythemia vera patients. Leukemia 2009;23:1441-1445.
    • (2009) Leukemia , vol.23 , pp. 1441-1445
    • Pardanani, A.1    Lasho, T.2    Smith, G.3
  • 149
    • 84928901823 scopus 로고    scopus 로고
    • Results of a phase 2 study of pacritinib (SB1518), a JAK2/JAK2(V617F) inhibitor, in patients with myelofibrosis
    • Komrokji RS, Seymour JF, Roberts AW, et al. Results of a phase 2 study of pacritinib (SB1518), a JAK2/JAK2(V617F) inhibitor, in patients with myelofibrosis. Blood 2015;125:2649-2655.
    • (2015) Blood , vol.125 , pp. 2649-2655
    • Komrokji, R.S.1    Seymour, J.F.2    Roberts, A.W.3
  • 150
    • 84940843616 scopus 로고    scopus 로고
    • Telomerase inhibitor imetelstat in patients with essential thrombocythemia
    • Baerlocher GM, Oppliger Leibundgut E, Ottmann OG, et al. Telomerase inhibitor imetelstat in patients with essential thrombocythemia. N Engl J Med 2015;373:920-928.
    • (2015) N Engl J Med , vol.373 , pp. 920-928
    • Baerlocher, G.M.1    Oppliger Leibundgut, E.2    Ottmann, O.G.3
  • 151
    • 84940845882 scopus 로고    scopus 로고
    • A pilot study of the telomerase inhibitor imetelstat for myelofibrosis
    • Tefferi A, Lasho TL, Begna KH, et al. A pilot study of the telomerase inhibitor imetelstat for myelofibrosis. N Engl J Med 2015;373:908-919.
    • (2015) N Engl J Med , vol.373 , pp. 908-919
    • Tefferi, A.1    Lasho, T.L.2    Begna, K.H.3
  • 152
    • 84930006828 scopus 로고    scopus 로고
    • Impact of allogeneic stem cell transplantation on survival of patients less than 65 years of age with primary myelofibrosis
    • quiz 3364.
    • Kroger N, Giorgino T, Scott BL, et al. Impact of allogeneic stem cell transplantation on survival of patients less than 65 years of age with primary myelofibrosis. Blood 2015;125:3347-3350. quiz 3364.
    • (2015) Blood , vol.125 , pp. 3347-3350
    • Kroger, N.1    Giorgino, T.2    Scott, B.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.