JAK2 germline genetic variation affects disease susceptibility in primary myelofibrosis regardless of V617F mutational status: Nullizygosity for the JAK2 46/1 haplotype is associated with inferior survival

Leukemia

Volumn 24, Issue 1, 2010, Pages 105-109

  Tefferi, A ^a   Lasho, T L ^a   Patnaik, M M ^a   Finke, C M ^a   Hussein, K ^a   Hogan, W J ^a   Elliott, M A ^a   Litzow, M R ^a   Hanson, C A ^a   Pardanani, A ^a  

^a MAYO CLINIC   (United States)

Author keywords

Haplotype; JAK2; Myelofibrosis; Prognosis; SNP; V617F

Indexed keywords

JANUS KINASE 2;

ADULT; AGED; ARTICLE; CONTROLLED STUDY; FEMALE; GENE FREQUENCY; GENE MUTATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; INTERNATIONAL PROGNOSTIC SCORING SYSTEM; KARYOTYPE; MAJOR CLINICAL STUDY; MALE; MALIGNANT TRANSFORMATION; MORTALITY; MYELOFIBROSIS; PRIORITY JOURNAL; PROGNOSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SPLENECTOMY; SURVIVAL RATE; SURVIVAL TIME; UNIPARENTAL DISOMY;

EID: 74249123815     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/leu.2009.225     Document Type: Article

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