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Volumn 131, Issue 3, 2005, Pages 320-328

The JAK2V617F tyrosine kinase mutation in myelofibrosis with myeloid metaplasia: Lineage specificity and clinical correlates

Author keywords

Clonality; JAK2; Mutation; Myelofibrosis; Polycythaemia vera; Prognosis

Indexed keywords

JANUS KINASE 2; PROTEIN TYROSINE KINASE; JAK2 PROTEIN, HUMAN; ONCOPROTEIN;

EID: 30844444135     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2005.05776.x     Document Type: Article
Times cited : (203)

References (52)
  • 2
    • 0033050680 scopus 로고    scopus 로고
    • A human erythropoietin receptor gene mutant causing familial erythrocytosis is associated with deregulation of the rates of Jak2 and Stat5 inactivation
    • Arcasoy M.O. Harris K.W. Forget B.G. (1999) A human erythropoietin receptor gene mutant causing familial erythrocytosis is associated with deregulation of the rates of Jak2 and Stat5 inactivation. Experimental Hematology, 27, 63 74.
    • (1999) Experimental Hematology , vol.27 , pp. 63-74
    • Arcasoy, M.O.1    Harris, K.W.2    Forget, B.G.3
  • 5
    • 0023753816 scopus 로고
    • Evidence for pluripotent stem cell origin of idiopathic myelofibrosis: Clonal analysis of a case characterized by a N-ras gene mutation
    • Buschle M. Janssen J.W. Drexler H. Lyons J. Anger B. Bartram C.R. (1988) Evidence for pluripotent stem cell origin of idiopathic myelofibrosis: clonal analysis of a case characterized by a N-ras gene mutation. Leukemia, 2, 658 660.
    • (1988) Leukemia , vol.2 , pp. 658-660
    • Buschle, M.1    Janssen, J.W.2    Drexler, H.3    Lyons, J.4    Anger, B.5    Bartram, C.R.6
  • 9
    • 0036041873 scopus 로고    scopus 로고
    • Myelofibrosis with myeloid metaplasia following essential thrombocythaemia: Actuarial probability, presenting characteristics and evolution in a series of 195 patients
    • Cervantes F. Alvarez-Larran A. Talarn C. Gomez M. Montserrat E. (2002) Myelofibrosis with myeloid metaplasia following essential thrombocythaemia: actuarial probability, presenting characteristics and evolution in a series of 195 patients. British Journal of Haematology, 118, 786 790.
    • (2002) British Journal of Haematology , vol.118 , pp. 786-790
    • Cervantes, F.1    Alvarez-Larran, A.2    Talarn, C.3    Gomez, M.4    Montserrat, E.5
  • 10
    • 0026649984 scopus 로고
    • High incidence of myeloproliferative disorders in Ashkenazi Jews in northern Israel
    • Chaiter Y. Brenner B. Aghai E. Tatarsky I. (1992) High incidence of myeloproliferative disorders in Ashkenazi Jews in northern Israel. Leukemia and Lymphoma, 7, 251 255.
    • (1992) Leukemia and Lymphoma , vol.7 , pp. 251-255
    • Chaiter, Y.1    Brenner, B.2    Aghai, E.3    Tatarsky, I.4
  • 12
    • 0035383807 scopus 로고    scopus 로고
    • Increased expression of the INK4a/ARF locus in polycythaemia vera
    • Dai C. Krantz S.B. (2001) Increased expression of the INK4a/ARF locus in polycythaemia vera. Blood, 97, 3424 3432.
    • (2001) Blood , vol.97 , pp. 3424-3432
    • Dai, C.1    Krantz, S.B.2
  • 13
    • 0033861096 scopus 로고    scopus 로고
    • JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells
    • De Vos J. Jourdan M. Tarte K. Jasmin C. Klein B. (2000) JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells. British Journal of Haematology, 109, 823 828.
    • (2000) British Journal of Haematology , vol.109 , pp. 823-828
    • De Vos, J.1    Jourdan, M.2    Tarte, K.3    Jasmin, C.4    Klein, B.5
  • 15
    • 0022255053 scopus 로고
    • The efficacy of direct, 24-hour culture, and mitotic synchronization methods for cytogenetic analysis of bone marrow in neoplastic hematologic disorders
    • Dewald G.W. Broderick D.J. Tom W.W. Hagstrom J.E. Pierre R.V. (1985) The efficacy of direct, 24-hour culture, and mitotic synchronization methods for cytogenetic analysis of bone marrow in neoplastic hematologic disorders. Cancer Genetics and Cytogenetics, 18, 1 10.
    • (1985) Cancer Genetics and Cytogenetics , vol.18 , pp. 1-10
    • Dewald, G.W.1    Broderick, D.J.2    Tom, W.W.3    Hagstrom, J.E.4    Pierre, R.V.5
  • 16
    • 0029767865 scopus 로고    scopus 로고
    • Prognostic factors in agnogenic myeloid metaplasia: A report on 195 cases with a new scoring system
    • Dupriez B. Morel P. Demory J.L. Lai J.L. Simon M. Plantier I. Bauters F. (1996) Prognostic factors in agnogenic myeloid metaplasia: a report on 195 cases with a new scoring system. Blood, 88, 1013 1018.
    • (1996) Blood , vol.88 , pp. 1013-1018
    • Dupriez, B.1    Morel, P.2    Demory, J.L.3    Lai, J.L.4    Simon, M.5    Plantier, I.6    Bauters, F.7
  • 17
    • 0017347539 scopus 로고
    • Polycythemia vera: Hormonal modulation of erythropoiesis in vitro
    • Golde D.W. Bersch N. Cline M.J. (1977) Polycythemia vera: hormonal modulation of erythropoiesis in vitro. Blood, 49, 399 405.
    • (1977) Blood , vol.49 , pp. 399-405
    • Golde, D.W.1    Bersch, N.2    Cline, M.J.3
  • 18
    • 17644417451 scopus 로고    scopus 로고
    • A unifying mutation in chronic myeloproliferative disorders
    • Goldman J.M. (2005) A unifying mutation in chronic myeloproliferative disorders. New England Journal of Medicine, 352, 1744 1746.
    • (2005) New England Journal of Medicine , vol.352 , pp. 1744-1746
    • Goldman, J.M.1
  • 21
    • 19344362958 scopus 로고    scopus 로고
    • On the molecular origins of the chronic myeloproliferative disorders: It all makes sense
    • Kaushansky K. (2005) On the molecular origins of the chronic myeloproliferative disorders: it all makes sense. Blood, 105, 4187 4190.
    • (2005) Blood , vol.105 , pp. 4187-4190
    • Kaushansky, K.1
  • 22
    • 0028956353 scopus 로고
    • Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals
    • Klingmuller U. Lorenz U. Cantley L.C. Neel B.G. Lodish H.F. (1995) Specific recruitment of SH-PTP1 to the erythropoietin receptor causes inactivation of JAK2 and termination of proliferative signals. Cell, 80, 729 738.
    • (1995) Cell , vol.80 , pp. 729-738
    • Klingmuller, U.1    Lorenz, U.2    Cantley, L.C.3    Neel, B.G.4    Lodish, H.F.5
  • 23
    • 0036191941 scopus 로고    scopus 로고
    • Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythaemia vera
    • Kralovics R. Guan Y. Prchal J.T. (2002) Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythaemia vera. Experimental Hematology, 30, 229 236.
    • (2002) Experimental Hematology , vol.30 , pp. 229-236
    • Kralovics, R.1    Guan, Y.2    Prchal, J.T.3
  • 24
    • 0041940289 scopus 로고    scopus 로고
    • Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders
    • Kralovics R. Buser A.S. Teo S.S. Coers J. Tichelli A. der Maas A.P. Skoda R.C. (2003) Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders. Blood, 102, 1869 1871.
    • (2003) Blood , vol.102 , pp. 1869-1871
    • Kralovics, R.1    Buser, A.S.2    Teo, S.S.3    Coers, J.4    Tichelli, A.5    Der Maas, A.P.6    Skoda, R.C.7
  • 28
    • 0034670052 scopus 로고    scopus 로고
    • Evaluation and clinical correlations of bone marrow angiogenesis in myelofibrosis with myeloid metaplasia
    • Mesa R.A. Hanson C.A. Rajkumar S.V. Schroeder G. Tefferi A. (2000) Evaluation and clinical correlations of bone marrow angiogenesis in myelofibrosis with myeloid metaplasia. Blood, 96, 3374 3380.
    • (2000) Blood , vol.96 , pp. 3374-3380
    • Mesa, R.A.1    Hanson, C.A.2    Rajkumar, S.V.3    Schroeder, G.4    Tefferi, A.5
  • 29
    • 0031687645 scopus 로고    scopus 로고
    • Epidemiological data in polycythaemia vera: A study of 842 cases
    • Najean Y. Rain J.D. Billotey C. (1998) Epidemiological data in polycythaemia vera: a study of 842 cases. Hematology and Cell Therapy, 40, 159 165.
    • (1998) Hematology and Cell Therapy , vol.40 , pp. 159-165
    • Najean, Y.1    Rain, J.D.2    Billotey, C.3
  • 30
    • 0036439588 scopus 로고    scopus 로고
    • Exploring polycythaemia vera with fluorescence in situ hybridization: Additional cryptic 9p is the most frequent abnormality detected
    • Najfeld V. Montella L. Scalise A. Fruchtman S. (2002) Exploring polycythaemia vera with fluorescence in situ hybridization: additional cryptic 9p is the most frequent abnormality detected. British Journal of Haematology, 119, 558 566.
    • (2002) British Journal of Haematology , vol.119 , pp. 558-566
    • Najfeld, V.1    Montella, L.2    Scalise, A.3    Fruchtman, S.4
  • 31
    • 0035257969 scopus 로고    scopus 로고
    • Primary chronic myelofibrosis: Clinical and prognostic evaluation in 336 Japanese patients
    • Okamura T. Kinukawa N. Niho Y. Mizoguchi H. (2001) Primary chronic myelofibrosis: clinical and prognostic evaluation in 336 Japanese patients. International Journal of Hematology, 73, 194 198.
    • (2001) International Journal of Hematology , vol.73 , pp. 194-198
    • Okamura, T.1    Kinukawa, N.2    Niho, Y.3    Mizoguchi, H.4
  • 34
    • 0037372287 scopus 로고    scopus 로고
    • Both B and T lymphocytes may be clonally involved in myelofibrosis with myeloid metaplasia
    • Reeder T.L. Bailey R.J. Dewald G.W. Tefferi A. (2003) Both B and T lymphocytes may be clonally involved in myelofibrosis with myeloid metaplasia. Blood, 101, 1981 1983.
    • (2003) Blood , vol.101 , pp. 1981-1983
    • Reeder, T.L.1    Bailey, R.J.2    Dewald, G.W.3    Tefferi, A.4
  • 35
    • 0034982338 scopus 로고    scopus 로고
    • STAT3 is constitutively active in some patients with polycythaemia rubra vera
    • Roder S. Steimle C. Meinhardt G. Pahl H.L. (2001) STAT3 is constitutively active in some patients with polycythaemia rubra vera. Experimental Hematology, 29, 694 702.
    • (2001) Experimental Hematology , vol.29 , pp. 694-702
    • Roder, S.1    Steimle, C.2    Meinhardt, G.3    Pahl, H.L.4
  • 37
    • 17144369135 scopus 로고    scopus 로고
    • Identification of 1,2,3,4,5,6-hexabromocyclohexane as a small molecule inhibitor of jak2 tyrosine kinase autophophorylation
    • Sandberg E.M. Ma X. He K. Frank S.J. Ostrov D.A. Sayeski P.P. (2005) Identification of 1,2,3,4,5,6-hexabromocyclohexane as a small molecule inhibitor of jak2 tyrosine kinase autophophorylation. Journal of Medicinal Chemistry, 48, 2526 2533.
    • (2005) Journal of Medicinal Chemistry , vol.48 , pp. 2526-2533
    • Sandberg, E.M.1    Ma, X.2    He, K.3    Frank, S.J.4    Ostrov, D.A.5    Sayeski, P.P.6
  • 38
    • 17444377587 scopus 로고    scopus 로고
    • JAKing up hematopoietic proliferation
    • Shannon K. Van Etten R.A. (2005) JAKing up hematopoietic proliferation. Cancer Cell, 7, 291 293.
    • (2005) Cancer Cell , vol.7 , pp. 291-293
    • Shannon, K.1    Van Etten, R.A.2
  • 39
    • 0030764557 scopus 로고    scopus 로고
    • Severe defects in immunity and hematopoiesis caused by SHP-1 protein-tyrosine-phosphatase deficiency
    • Shultz L.D. Rajan T.V. Greiner D.L. (1997) Severe defects in immunity and hematopoiesis caused by SHP-1 protein-tyrosine-phosphatase deficiency. Trends Biotechnology, 15, 302 307.
    • (1997) Trends Biotechnology , vol.15 , pp. 302-307
    • Shultz, L.D.1    Rajan, T.V.2    Greiner, D.L.3
  • 42
    • 0033597715 scopus 로고    scopus 로고
    • Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: A direct role for Stat5 in Bcl-X(L) induction
    • Socolovsky M. Fallon A.E. Wang S. Brugnara C. Lodish H.F. (1999) Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction. Cell, 98, 181 191.
    • (1999) Cell , vol.98 , pp. 181-191
    • Socolovsky, M.1    Fallon, A.E.2    Wang, S.3    Brugnara, C.4    Lodish, H.F.5
  • 43
    • 21344440357 scopus 로고    scopus 로고
    • The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both ''atypical" myeloproliferative disorders and myelodysplastic syndromes
    • Steensma D.P. Dewald G.W. Lasho T.L. Powell H.L. McClure R.F. Levine R.L. Gilliland D.G. Tefferi A. (2005) The JAK2 V617F activating tyrosine kinase mutation is an infrequent event in both ''atypical" myeloproliferative disorders and myelodysplastic syndromes. Blood, 106, 1207 1209.
    • (2005) Blood , vol.106 , pp. 1207-1209
    • Steensma, D.P.1    Dewald, G.W.2    Lasho, T.L.3    Powell, H.L.4    McClure, R.F.5    Levine, R.L.6    Gilliland, D.G.7    Tefferi, A.8
  • 44
    • 0034720161 scopus 로고    scopus 로고
    • Myelofibrosis with Myeloid Metaplasia
    • Tefferi A. (2000) Myelofibrosis with Myeloid Metaplasia. New England Journal of Medicine, 342, 1255 1265.
    • (2000) New England Journal of Medicine , vol.342 , pp. 1255-1265
    • Tefferi, A.1
  • 45
    • 0037247488 scopus 로고    scopus 로고
    • Treatment approaches in myelofibrosis with myeloid metaplasia: The old and the new
    • Tefferi A. (2003) Treatment approaches in myelofibrosis with myeloid metaplasia: The old and the new. Seminars in Hematology, 40, 18 21.
    • (2003) Seminars in Hematology , vol.40 , pp. 18-21
    • Tefferi, A.1
  • 46
    • 3242742988 scopus 로고    scopus 로고
    • FIP1L1-PDGFRA and c-kit D816 V mutation-based clonality studies in systemic mast cell disease associated with eosinophilia
    • Tefferi A. Lasho T.L. Brockman S.R. Elliott M.A. Dispenzieri A. Pardanani A. (2004) FIP1L1-PDGFRA and c-kit D816 V mutation-based clonality studies in systemic mast cell disease associated with eosinophilia. Haematologica, 89, 871 873.
    • (2004) Haematologica , vol.89 , pp. 871-873
    • Tefferi, A.1    Lasho, T.L.2    Brockman, S.R.3    Elliott, M.A.4    Dispenzieri, A.5    Pardanani, A.6
  • 48
    • 30844456807 scopus 로고    scopus 로고
    • WHO histological classification of chronic myeloproliferative diseases
    • In: ed. by. E.S. Jaffe. N.L. Harris. H. Stein. J.W. Vardiman. pp. International Agency for Research on Cancer (IARC) Press, Lyon, France.
    • Vardiman J.W. Brunning R.D. Harris N.L. (2001) WHO histological classification of chronic myeloproliferative diseases. In: World Health Organization Classification of Tumors: Tumours of the Haematopoietic and Lymphoid Tissues (ed. by E.S. Jaffe N.L. Harris H. Stein J.W. Vardiman pp. 17 44. International Agency for Research on Cancer (IARC) Press, Lyon, France.
    • (2001) World Health Organization Classification of Tumors: Tumours of the Haematopoietic and Lymphoid Tissues , pp. 17-44
    • Vardiman, J.W.1    Brunning, R.D.2    Harris, N.L.3
  • 49
    • 0035351213 scopus 로고    scopus 로고
    • Polycythemia vera: Analysis of DNA from blood granulocytes using comparative genomic hybridization
    • Westwood N.B. Gruszka-Westwood A.M. Atkinson S. Pearson T.C. (2001) Polycythemia vera: analysis of DNA from blood granulocytes using comparative genomic hybridization. Haematologica, 86, 464 469.
    • (2001) Haematologica , vol.86 , pp. 464-469
    • Westwood, N.B.1    Gruszka-Westwood, A.M.2    Atkinson, S.3    Pearson, T.C.4
  • 50
    • 0032854508 scopus 로고    scopus 로고
    • Bone marrow effects of anagrelide therapy in patients with myelofibrosis with myeloid metaplasia
    • Yoon S.Y. Li C.Y. Mesa R.A. Tefferi A. (1999) Bone marrow effects of anagrelide therapy in patients with myelofibrosis with myeloid metaplasia. British Journal of Haematology, 106, 682 688.
    • (1999) British Journal of Haematology , vol.106 , pp. 682-688
    • Yoon, S.Y.1    Li, C.Y.2    Mesa, R.A.3    Tefferi, A.4
  • 51
    • 0017755475 scopus 로고
    • Erythroid colony formation by polycythaemia vera bone marrow in vitro. Dependence on erythropoietin
    • Zanjani E.D. Lutton J.D. Hoffman R. Wasserman L.R. (1977) Erythroid colony formation by polycythaemia vera bone marrow in vitro. Dependence on erythropoietin. Journal of Clinical Investigation, 59, 841 848.
    • (1977) Journal of Clinical Investigation , vol.59 , pp. 841-848
    • Zanjani, E.D.1    Lutton, J.D.2    Hoffman, R.3    Wasserman, L.R.4


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