Clinical implications of the JAK2 V617F mutation in essential thrombocythemia [7]

Leukemia

Volumn 19, Issue 10, 2005, Pages 1847-1849

  Antonioli, E ^a   Guglielmelli, P ^a   Pancrazzi, A ^a   Bogani, C ^a   Verrucci, M ^a   Ponziani, V ^a   Longo, G ^a   Bosi, A ^a   Vannucchi, A M ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN; JANUS KINASE 2; PHENYLALANINE; PROTEIN TYROSINE KINASE; VALINE;

ALLELE; AMINO ACID SUBSTITUTION; BLEEDING; BLOOD SAMPLING; CHI SQUARE TEST; CORRELATION ANALYSIS; EXON; FISHER EXACT TEST; GENE MUTATION; GENE OVEREXPRESSION; GENETIC ASSOCIATION; HEMATOCRIT; HISTOPATHOLOGY; HOMOZYGOSITY; HUMAN; LETTER; MYELOPROLIFERATIVE DISORDER; PHENOTYPE; PRIORITY JOURNAL; RANK SUM TEST; THROMBOCYTHEMIA; THROMBOSIS; WILD TYPE; X CHROMOSOME;

EID: 27144443646     PISSN: 08876924     EISSN: 14765551     Source Type: Journal    
DOI: 10.1038/sj.leu.2403902     Document Type: Letter

References (8)

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2. Baxter EJ, Scott LM, Campbell PJ, East C, Fourouclas N, Swanton S et al. Acquired mutation of the tyrosine kinase JAK2 in human myeloproliferative disorders. Lancet 2005; 365: 1054-1061.
3. James C, Ugo V, Le Couedic JP, Staerk J, Delhommeau F, Lacout C et al. A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. Nature 2005; 434: 1144-1148.
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6. Kralovics R, Guan Y, Prchal JT. Acquired uniparental disomy of chromosome 9p is a frequent stem cell defect in polycythemia vera. Exp Hematol 2002; 30: 229-236.
7. Imbert M, Pierre R, Thiele J, Vardiman JW, Brunning RD, Flandrin G. Essential thrombocythaemia. In: Jaffe ES, Harris NL, Stein H et al (eds). WHO Classification of Tumors: Tumors of Hematopoietic and Lymphois Tissues. Lyon: IARC Press, 2001, pp 39-41.
8. Vannucchi AM, Grossi A, Pancrazzi A, Antonioli E, Guglielmelli P, Balestri F et al. PRV-1, erythroid colonies and platelet Mpl are unrelated to thrombosis in essential thrombocythaemia. Br J Haematol 2004; 127: 214-219.