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Volumn 75, Issue 1, 2016, Pages 303-310

Downregulation of miR-193b in systemic sclerosis regulates the proliferative vasculopathy by urokinase-type plasminogen activator expression

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 193B; UNCLASSIFIED DRUG; UROKINASE; CYTOKINE; MIRN193 MICRORNA, HUMAN;

EID: 84954216511     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2014-205326     Document Type: Article
Times cited : (43)

References (42)
  • 1
    • 0043074631 scopus 로고    scopus 로고
    • Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population
    • Mayes MD, Lacey JV Jr, Beebe-Dimmer J, et al. Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population. Arthritis Rheum 2003;48:2246-55.
    • (2003) Arthritis Rheum , vol.48 , pp. 2246-2255
    • Mayes, M.D.1    Lacey, J.V.2    Beebe-Dimmer, J.3
  • 2
    • 67649649822 scopus 로고    scopus 로고
    • Overview of pathogenesis of systemic sclerosis
    • Abraham DJ, Krieg T, Distler J, et al. Overview of pathogenesis of systemic sclerosis. Rheumatology (Oxford) 2009;48(Suppl 3):iii3-7.
    • (2009) Rheumatology (Oxford) , vol.48 , pp. iii3-7
    • Abraham, D.J.1    Krieg, T.2    Distler, J.3
  • 4
    • 0028866373 scopus 로고
    • Increased prevalence of symptomatic macrovascular disease in systemic sclerosis
    • Veale DJ, Collidge TA, Belch JJ. Increased prevalence of symptomatic macrovascular disease in systemic sclerosis. Ann Rheum Dis 1995;54:853-5.
    • (1995) Ann Rheum Dis , vol.54 , pp. 853-855
    • Veale, D.J.1    Collidge, T.A.2    Belch, J.J.3
  • 5
    • 0027183767 scopus 로고
    • Large vessel occlusive disease associated with CREST syndrome and scleroderma
    • Youssef P, Englert H, Bertouch J. Large vessel occlusive disease associated with CREST syndrome and scleroderma. Ann Rheum Dis 1993;52:464-6.
    • (1993) Ann Rheum Dis , vol.52 , pp. 464-466
    • Youssef, P.1    Englert, H.2    Bertouch, J.3
  • 6
    • 13844256438 scopus 로고    scopus 로고
    • The urokinase plasminogen activator and its receptor: Role in cell growth and apoptosis
    • Alfano D, Franco P, Vocca I, et al. The urokinase plasminogen activator and its receptor: role in cell growth and apoptosis. Thromb Haemost 2005;93:205-11.
    • (2005) Thromb Haemost , vol.93 , pp. 205-211
    • Alfano, D.1    Franco, P.2    Vocca, I.3
  • 7
    • 0036906177 scopus 로고    scopus 로고
    • UPAR: A versatile signalling orchestrator
    • Blasi F, Carmeliet P. uPAR: a versatile signalling orchestrator. Nat Rev Mol Cell Biol 2002;3:932-43.
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 932-943
    • Blasi, F.1    Carmeliet, P.2
  • 8
    • 0037622867 scopus 로고    scopus 로고
    • The urokinase plasminogen activator receptor in the regulation of the actin cytoskeleton and cell motility
    • Kjoller L. The urokinase plasminogen activator receptor in the regulation of the actin cytoskeleton and cell motility. Biol Chem 2002;383:5-19.
    • (2002) Biol Chem , vol.383 , pp. 5-19
    • Kjoller, L.1
  • 9
    • 65249116364 scopus 로고    scopus 로고
    • Regulation of arterial remodeling and angiogenesis by urokinase-type plasminogen activator
    • Tkachuk VA, Plekhanova OS, Parfyonova YV. Regulation of arterial remodeling and angiogenesis by urokinase-type plasminogen activator. Can J Physiol Pharmacol 2009;87:231-51.
    • (2009) Can J Physiol Pharmacol , vol.87 , pp. 231-251
    • Tkachuk, V.A.1    Plekhanova, O.S.2    Parfyonova, Y.V.3
  • 10
    • 2942726214 scopus 로고    scopus 로고
    • Contrasting effects of urokinase and tissue-type plasminogen activators on neointima formation and vessel remodelling after arterial injury
    • Parfyonova Y, Plekhanova O, Solomatina M, et al. Contrasting effects of urokinase and tissue-type plasminogen activators on neointima formation and vessel remodelling after arterial injury. J Vasc Res 2004;41:268-76.
    • (2004) J Vasc Res , vol.41 , pp. 268-276
    • Parfyonova, Y.1    Plekhanova, O.2    Solomatina, M.3
  • 11
    • 0033851467 scopus 로고    scopus 로고
    • Urokinase plasminogen activator enhances neointima growth and reduces lumen size in injured carotid arteries
    • Plekhanova OS, Parfyonova YV, Bibilashvily R, et al. Urokinase plasminogen activator enhances neointima growth and reduces lumen size in injured carotid arteries. J Hypertens 2000;18:1065-9.
    • (2000) J Hypertens , vol.18 , pp. 1065-1069
    • Plekhanova, O.S.1    Parfyonova, Y.V.2    Bibilashvily, R.3
  • 12
    • 5644277559 scopus 로고    scopus 로고
    • Matrix metalloproteinase 12-dependent cleavage of urokinase receptor in systemic sclerosis microvascular endothelial cells results in impaired angiogenesis
    • D'Alessio S, Fibbi G, Cinelli M, et al. Matrix metalloproteinase 12-dependent cleavage of urokinase receptor in systemic sclerosis microvascular endothelial cells results in impaired angiogenesis. Arthritis Rheum 2004;50:3275-85.
    • (2004) Arthritis Rheum , vol.50 , pp. 3275-3285
    • D'Alessio, S.1    Fibbi, G.2    Cinelli, M.3
  • 13
    • 33845666597 scopus 로고    scopus 로고
    • Domain 1 of the urokinase-type plasminogen activator receptor is required for its morphologic and functional, beta2 integrin-mediated connection with actin cytoskeleton in human microvascular endothelial cells: Failure of association in systemic sclerosis endothelial cells
    • Margheri F, Manetti M, Serrati S, et al. Domain 1 of the urokinase-type plasminogen activator receptor is required for its morphologic and functional, beta2 integrin-mediated connection with actin cytoskeleton in human microvascular endothelial cells: failure of association in systemic sclerosis endothelial cells. Arthritis Rheum 2006;54:3926-38.
    • (2006) Arthritis Rheum , vol.54 , pp. 3926-3938
    • Margheri, F.1    Manetti, M.2    Serrati, S.3
  • 14
    • 84905158456 scopus 로고    scopus 로고
    • Inactivation of urokinase-type plasminogen activator receptor (uPAR) gene induces dermal and pulmonary fibrosis and peripheral microvasculopathy in mice: A new model of experimental scleroderma?
    • Manetti M, Rosa I, Milia AF, et al. Inactivation of urokinase-type plasminogen activator receptor (uPAR) gene induces dermal and pulmonary fibrosis and peripheral microvasculopathy in mice: a new model of experimental scleroderma? Ann Rheum Dis 2014;73:1700-9.
    • (2014) Ann Rheum Dis , vol.73 , pp. 1700-1709
    • Manetti, M.1    Rosa, I.2    Milia, A.F.3
  • 15
    • 55049113363 scopus 로고    scopus 로고
    • Evolution of microRNAs and their targets: Are all microRNAs biologically relevant?
    • Axtell MJ. Evolution of microRNAs and their targets: are all microRNAs biologically relevant? Biochim Biophys Acta 2008;1779:725-34.
    • (2008) Biochim Biophys Acta , vol.1779 , pp. 725-734
    • Axtell, M.J.1
  • 16
    • 73649110251 scopus 로고    scopus 로고
    • Genomic organization of microRNAs
    • Olena AF, Patton JG. Genomic organization of microRNAs. J Cell Physiol 2010;222:540-5.
    • (2010) J Cell Physiol , vol.222 , pp. 540-545
    • Olena, A.F.1    Patton, J.G.2
  • 17
    • 0346094457 scopus 로고    scopus 로고
    • Prediction of mammalian microRNA targets
    • Lewis BP, Shih IH, Jones-Rhoades MW, et al. Prediction of mammalian microRNA targets. Cell 2003;115:787-98.
    • (2003) Cell , vol.115 , pp. 787-798
    • Lewis, B.P.1    Shih, I.H.2    Jones-Rhoades, M.W.3
  • 18
  • 19
    • 81155124251 scopus 로고    scopus 로고
    • MicroRNAs in the pathogenesis of cancer
    • Lovat F, Valeri N, Croce CM. MicroRNAs in the pathogenesis of cancer. Semin Oncol 2011;38:724-33.
    • (2011) Semin Oncol , vol.38 , pp. 724-733
    • Lovat, F.1    Valeri, N.2    Croce, C.M.3
  • 20
    • 83055163828 scopus 로고    scopus 로고
    • The emerging important role of microRNAs in the pathogenesis, diagnosis and treatment of human cancers
    • Wilmott JS, Zhang XD, Hersey P, et al. The emerging important role of microRNAs in the pathogenesis, diagnosis and treatment of human cancers. Pathology 2011;43:657-71.
    • (2011) Pathology , vol.43 , pp. 657-671
    • Wilmott, J.S.1    Zhang, X.D.2    Hersey, P.3
  • 21
    • 38749089854 scopus 로고    scopus 로고
    • MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma
    • Schetter AJ, Leung SY, Sohn JJ, et al. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA 2008;299:425-36.
    • (2008) JAMA , vol.299 , pp. 425-436
    • Schetter, A.J.1    Leung, S.Y.2    Sohn, J.J.3
  • 22
    • 84857063439 scopus 로고    scopus 로고
    • MicroRNA array analysis of microRNAs related to systemic scleroderma
    • Li H, Yang R, Fan X, et al. MicroRNA array analysis of microRNAs related to systemic scleroderma. Rheumatol Int 2012;32:307-13.
    • (2012) Rheumatol Int , vol.32 , pp. 307-313
    • Li, H.1    Yang, R.2    Fan, X.3
  • 23
    • 79551655444 scopus 로고    scopus 로고
    • Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation
    • Stanczyk J, Ospelt C, Karouzakis E, et al. Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. Arthritis Rheum 2011;63:373-81.
    • (2011) Arthritis Rheum , vol.63 , pp. 373-381
    • Stanczyk, J.1    Ospelt, C.2    Karouzakis, E.3
  • 24
    • 77952946050 scopus 로고    scopus 로고
    • MicroRNA-29, a key regulator of collagen expression in systemic sclerosis
    • Maurer B, Stanczyk J, Jungel A, et al. MicroRNA-29, a key regulator of collagen expression in systemic sclerosis. Arthritis Rheum 2010;62:1733-43.
    • (2010) Arthritis Rheum , vol.62 , pp. 1733-1743
    • Maurer, B.1    Stanczyk, J.2    Jungel, A.3
  • 25
    • 0023854176 scopus 로고
    • Scleroderma (systemic sclerosis): Classification, subsets and pathogenesis
    • LeRoy EC, Black C, Fleischmajer R, et al. Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 1988;15:202-5.
    • (1988) J Rheumatol , vol.15 , pp. 202-205
    • LeRoy, E.C.1    Black, C.2    Fleischmajer, R.3
  • 26
    • 0345827523 scopus 로고    scopus 로고
    • Physiologic responses to hypoxia and implications for hypoxia-inducible factors in the pathogenesis of rheumatoid arthritis
    • Distler JH, Wenger RH, Gassmann M, et al. Physiologic responses to hypoxia and implications for hypoxia-inducible factors in the pathogenesis of rheumatoid arthritis. Arthritis Rheum 2004;50:10-23.
    • (2004) Arthritis Rheum , vol.50 , pp. 10-23
    • Distler, J.H.1    Wenger, R.H.2    Gassmann, M.3
  • 27
    • 80052453175 scopus 로고    scopus 로고
    • SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance
    • Niederer F, Ospelt C, Brentano F, et al. SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance. Ann Rheum Dis 2011;70:1866-73.
    • (2011) Ann Rheum Dis , vol.70 , pp. 1866-1873
    • Niederer, F.1    Ospelt, C.2    Brentano, F.3
  • 28
    • 33846209989 scopus 로고    scopus 로고
    • Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis
    • Distler JH, Jungel A, Huber LC, et al. Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis. Arthritis Rheum 2007;56:311-22.
    • (2007) Arthritis Rheum , vol.56 , pp. 311-322
    • Distler, J.H.1    Jungel, A.2    Huber, L.C.3
  • 29
    • 71049129806 scopus 로고    scopus 로고
    • Identification of a novel microRNA cluster miR-193b-365 in multiple myeloma
    • Unno K, Zhou Y, Zimmerman T, et al. Identification of a novel microRNA cluster miR-193b-365 in multiple myeloma. Leuk Lymphoma 2009; 50:1865-71.
    • (2009) Leuk Lymphoma , vol.50 , pp. 1865-1871
    • Unno, K.1    Zhou, Y.2    Zimmerman, T.3
  • 30
    • 37149006718 scopus 로고    scopus 로고
    • Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis
    • Distler JH, Jungel A, Pileckyte M, et al. Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis. Arthritis Rheum 2007;56:4203-15.
    • (2007) Arthritis Rheum , vol.56 , pp. 4203-4215
    • Distler, J.H.1    Jungel, A.2    Pileckyte, M.3
  • 31
    • 49949114547 scopus 로고    scopus 로고
    • Molecular subsets in the gene expression signatures of scleroderma skin
    • Milano A, Pendergrass SA, Sargent JL, et al. Molecular subsets in the gene expression signatures of scleroderma skin. PLoS ONE 2008;3:e2696.
    • (2008) PLoS ONE , vol.3 , pp. e2696
    • Milano, A.1    Pendergrass, S.A.2    Sargent, J.L.3
  • 32
    • 20444483234 scopus 로고    scopus 로고
    • Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension
    • McMurtry MS, Archer SL, Altieri DC, et al. Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension. J Clin Invest 2005;115:1479-91.
    • (2005) J Clin Invest , vol.115 , pp. 1479-1491
    • McMurtry, M.S.1    Archer, S.L.2    Altieri, D.C.3
  • 33
    • 6344257102 scopus 로고    scopus 로고
    • Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis
    • McMurtry MS, Bonnet S, Wu X, et al. Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis. Circ Res 2004;95:830-40.
    • (2004) Circ Res , vol.95 , pp. 830-840
    • McMurtry, M.S.1    Bonnet, S.2    Wu, X.3
  • 34
    • 13444272087 scopus 로고    scopus 로고
    • Entrez Gene: Gene-centered information at NCBI
    • Maglott D, Ostell J, Pruitt KD, et al. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res 2005;33:D54-8.
    • (2005) Nucleic Acids Res , vol.33 , pp. D54-D58
    • Maglott, D.1    Ostell, J.2    Pruitt, K.D.3
  • 35
    • 24944530570 scopus 로고    scopus 로고
    • The fibrinolytic system components are increased in systemic sclerosis and modulated by Alprostadil (alpha1 ciclodestryn)
    • Bandinelli F, Bartoli F, Perfetto E, et al. The fibrinolytic system components are increased in systemic sclerosis and modulated by Alprostadil (alpha1 ciclodestryn). Clin Exp Rheumatol 2005;23:671-7.
    • (2005) Clin Exp Rheumatol , vol.23 , pp. 671-677
    • Bandinelli, F.1    Bartoli, F.2    Perfetto, E.3
  • 36
    • 78149269955 scopus 로고    scopus 로고
    • The plasminogen activator system in fibroblasts from systemic sclerosis
    • Postiglione L, Montuori N, Riccio A, et al. The plasminogen activator system in fibroblasts from systemic sclerosis. Int J Immunopathol Pharmacol 2010;23:891-900.
    • (2010) Int J Immunopathol Pharmacol , vol.23 , pp. 891-900
    • Postiglione, L.1    Montuori, N.2    Riccio, A.3
  • 37
    • 80055000875 scopus 로고    scopus 로고
    • MiR-193b regulates Mcl-1 in Melanoma
    • Chen J, Zhang X, Lentz C, et al. miR-193b Regulates Mcl-1 in Melanoma. Am J Pathol 2011;179:2162-8.
    • (2011) Am J Pathol , vol.179 , pp. 2162-2168
    • Chen, J.1    Zhang, X.2    Lentz, C.3
  • 38
    • 80455166015 scopus 로고    scopus 로고
    • Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact
    • 005322
    • Leivonen SK, Rokka A, Ostling P, et al. Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact. Mol Cell Proteomics 2011;10:M110 005322.
    • (2011) Mol Cell Proteomics , vol.10 , pp. M110
    • Leivonen, S.K.1    Rokka, A.2    Ostling, P.3
  • 39
    • 70449124422 scopus 로고    scopus 로고
    • Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer
    • Li XF, Yan PJ, Shao ZM. Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer. Oncogene 2009;28:3937-48.
    • (2009) Oncogene , vol.28 , pp. 3937-3948
    • Li, X.F.1    Yan, P.J.2    Shao, Z.M.3
  • 40
    • 77955590791 scopus 로고    scopus 로고
    • MiR-193b is an epigenetically regulated putative tumor suppressor in prostate cancer
    • Rauhala HE, Jalava SE, Isotalo J, et al. miR-193b is an epigenetically regulated putative tumor suppressor in prostate cancer. Int J Cancer 2010;127:1363-72.
    • (2010) Int J Cancer , vol.127 , pp. 1363-1372
    • Rauhala, H.E.1    Jalava, S.E.2    Isotalo, J.3
  • 42
    • 57749168828 scopus 로고    scopus 로고
    • MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
    • Thum T, Gross C, Fiedler J, et al. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 2008;456:980-4.
    • (2008) Nature , vol.456 , pp. 980-984
    • Thum, T.1    Gross, C.2    Fiedler, J.3


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