-
1
-
-
0043074631
-
Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population
-
Mayes MD, Lacey JV Jr, Beebe-Dimmer J, et al. Prevalence, incidence, survival, and disease characteristics of systemic sclerosis in a large US population. Arthritis Rheum 2003;48:2246-55.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2246-2255
-
-
Mayes, M.D.1
Lacey, J.V.2
Beebe-Dimmer, J.3
-
4
-
-
0028866373
-
Increased prevalence of symptomatic macrovascular disease in systemic sclerosis
-
Veale DJ, Collidge TA, Belch JJ. Increased prevalence of symptomatic macrovascular disease in systemic sclerosis. Ann Rheum Dis 1995;54:853-5.
-
(1995)
Ann Rheum Dis
, vol.54
, pp. 853-855
-
-
Veale, D.J.1
Collidge, T.A.2
Belch, J.J.3
-
5
-
-
0027183767
-
Large vessel occlusive disease associated with CREST syndrome and scleroderma
-
Youssef P, Englert H, Bertouch J. Large vessel occlusive disease associated with CREST syndrome and scleroderma. Ann Rheum Dis 1993;52:464-6.
-
(1993)
Ann Rheum Dis
, vol.52
, pp. 464-466
-
-
Youssef, P.1
Englert, H.2
Bertouch, J.3
-
6
-
-
13844256438
-
The urokinase plasminogen activator and its receptor: Role in cell growth and apoptosis
-
Alfano D, Franco P, Vocca I, et al. The urokinase plasminogen activator and its receptor: role in cell growth and apoptosis. Thromb Haemost 2005;93:205-11.
-
(2005)
Thromb Haemost
, vol.93
, pp. 205-211
-
-
Alfano, D.1
Franco, P.2
Vocca, I.3
-
7
-
-
0036906177
-
UPAR: A versatile signalling orchestrator
-
Blasi F, Carmeliet P. uPAR: a versatile signalling orchestrator. Nat Rev Mol Cell Biol 2002;3:932-43.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 932-943
-
-
Blasi, F.1
Carmeliet, P.2
-
8
-
-
0037622867
-
The urokinase plasminogen activator receptor in the regulation of the actin cytoskeleton and cell motility
-
Kjoller L. The urokinase plasminogen activator receptor in the regulation of the actin cytoskeleton and cell motility. Biol Chem 2002;383:5-19.
-
(2002)
Biol Chem
, vol.383
, pp. 5-19
-
-
Kjoller, L.1
-
9
-
-
65249116364
-
Regulation of arterial remodeling and angiogenesis by urokinase-type plasminogen activator
-
Tkachuk VA, Plekhanova OS, Parfyonova YV. Regulation of arterial remodeling and angiogenesis by urokinase-type plasminogen activator. Can J Physiol Pharmacol 2009;87:231-51.
-
(2009)
Can J Physiol Pharmacol
, vol.87
, pp. 231-251
-
-
Tkachuk, V.A.1
Plekhanova, O.S.2
Parfyonova, Y.V.3
-
10
-
-
2942726214
-
Contrasting effects of urokinase and tissue-type plasminogen activators on neointima formation and vessel remodelling after arterial injury
-
Parfyonova Y, Plekhanova O, Solomatina M, et al. Contrasting effects of urokinase and tissue-type plasminogen activators on neointima formation and vessel remodelling after arterial injury. J Vasc Res 2004;41:268-76.
-
(2004)
J Vasc Res
, vol.41
, pp. 268-276
-
-
Parfyonova, Y.1
Plekhanova, O.2
Solomatina, M.3
-
11
-
-
0033851467
-
Urokinase plasminogen activator enhances neointima growth and reduces lumen size in injured carotid arteries
-
Plekhanova OS, Parfyonova YV, Bibilashvily R, et al. Urokinase plasminogen activator enhances neointima growth and reduces lumen size in injured carotid arteries. J Hypertens 2000;18:1065-9.
-
(2000)
J Hypertens
, vol.18
, pp. 1065-1069
-
-
Plekhanova, O.S.1
Parfyonova, Y.V.2
Bibilashvily, R.3
-
12
-
-
5644277559
-
Matrix metalloproteinase 12-dependent cleavage of urokinase receptor in systemic sclerosis microvascular endothelial cells results in impaired angiogenesis
-
D'Alessio S, Fibbi G, Cinelli M, et al. Matrix metalloproteinase 12-dependent cleavage of urokinase receptor in systemic sclerosis microvascular endothelial cells results in impaired angiogenesis. Arthritis Rheum 2004;50:3275-85.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3275-3285
-
-
D'Alessio, S.1
Fibbi, G.2
Cinelli, M.3
-
13
-
-
33845666597
-
Domain 1 of the urokinase-type plasminogen activator receptor is required for its morphologic and functional, beta2 integrin-mediated connection with actin cytoskeleton in human microvascular endothelial cells: Failure of association in systemic sclerosis endothelial cells
-
Margheri F, Manetti M, Serrati S, et al. Domain 1 of the urokinase-type plasminogen activator receptor is required for its morphologic and functional, beta2 integrin-mediated connection with actin cytoskeleton in human microvascular endothelial cells: failure of association in systemic sclerosis endothelial cells. Arthritis Rheum 2006;54:3926-38.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 3926-3938
-
-
Margheri, F.1
Manetti, M.2
Serrati, S.3
-
14
-
-
84905158456
-
Inactivation of urokinase-type plasminogen activator receptor (uPAR) gene induces dermal and pulmonary fibrosis and peripheral microvasculopathy in mice: A new model of experimental scleroderma?
-
Manetti M, Rosa I, Milia AF, et al. Inactivation of urokinase-type plasminogen activator receptor (uPAR) gene induces dermal and pulmonary fibrosis and peripheral microvasculopathy in mice: a new model of experimental scleroderma? Ann Rheum Dis 2014;73:1700-9.
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 1700-1709
-
-
Manetti, M.1
Rosa, I.2
Milia, A.F.3
-
15
-
-
55049113363
-
Evolution of microRNAs and their targets: Are all microRNAs biologically relevant?
-
Axtell MJ. Evolution of microRNAs and their targets: are all microRNAs biologically relevant? Biochim Biophys Acta 2008;1779:725-34.
-
(2008)
Biochim Biophys Acta
, vol.1779
, pp. 725-734
-
-
Axtell, M.J.1
-
16
-
-
73649110251
-
Genomic organization of microRNAs
-
Olena AF, Patton JG. Genomic organization of microRNAs. J Cell Physiol 2010;222:540-5.
-
(2010)
J Cell Physiol
, vol.222
, pp. 540-545
-
-
Olena, A.F.1
Patton, J.G.2
-
17
-
-
0346094457
-
Prediction of mammalian microRNA targets
-
Lewis BP, Shih IH, Jones-Rhoades MW, et al. Prediction of mammalian microRNA targets. Cell 2003;115:787-98.
-
(2003)
Cell
, vol.115
, pp. 787-798
-
-
Lewis, B.P.1
Shih, I.H.2
Jones-Rhoades, M.W.3
-
19
-
-
81155124251
-
MicroRNAs in the pathogenesis of cancer
-
Lovat F, Valeri N, Croce CM. MicroRNAs in the pathogenesis of cancer. Semin Oncol 2011;38:724-33.
-
(2011)
Semin Oncol
, vol.38
, pp. 724-733
-
-
Lovat, F.1
Valeri, N.2
Croce, C.M.3
-
20
-
-
83055163828
-
The emerging important role of microRNAs in the pathogenesis, diagnosis and treatment of human cancers
-
Wilmott JS, Zhang XD, Hersey P, et al. The emerging important role of microRNAs in the pathogenesis, diagnosis and treatment of human cancers. Pathology 2011;43:657-71.
-
(2011)
Pathology
, vol.43
, pp. 657-671
-
-
Wilmott, J.S.1
Zhang, X.D.2
Hersey, P.3
-
21
-
-
38749089854
-
MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma
-
Schetter AJ, Leung SY, Sohn JJ, et al. MicroRNA expression profiles associated with prognosis and therapeutic outcome in colon adenocarcinoma. JAMA 2008;299:425-36.
-
(2008)
JAMA
, vol.299
, pp. 425-436
-
-
Schetter, A.J.1
Leung, S.Y.2
Sohn, J.J.3
-
22
-
-
84857063439
-
MicroRNA array analysis of microRNAs related to systemic scleroderma
-
Li H, Yang R, Fan X, et al. MicroRNA array analysis of microRNAs related to systemic scleroderma. Rheumatol Int 2012;32:307-13.
-
(2012)
Rheumatol Int
, vol.32
, pp. 307-313
-
-
Li, H.1
Yang, R.2
Fan, X.3
-
23
-
-
79551655444
-
Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation
-
Stanczyk J, Ospelt C, Karouzakis E, et al. Altered expression of microRNA-203 in rheumatoid arthritis synovial fibroblasts and its role in fibroblast activation. Arthritis Rheum 2011;63:373-81.
-
(2011)
Arthritis Rheum
, vol.63
, pp. 373-381
-
-
Stanczyk, J.1
Ospelt, C.2
Karouzakis, E.3
-
24
-
-
77952946050
-
MicroRNA-29, a key regulator of collagen expression in systemic sclerosis
-
Maurer B, Stanczyk J, Jungel A, et al. MicroRNA-29, a key regulator of collagen expression in systemic sclerosis. Arthritis Rheum 2010;62:1733-43.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1733-1743
-
-
Maurer, B.1
Stanczyk, J.2
Jungel, A.3
-
25
-
-
0023854176
-
Scleroderma (systemic sclerosis): Classification, subsets and pathogenesis
-
LeRoy EC, Black C, Fleischmajer R, et al. Scleroderma (systemic sclerosis): classification, subsets and pathogenesis. J Rheumatol 1988;15:202-5.
-
(1988)
J Rheumatol
, vol.15
, pp. 202-205
-
-
LeRoy, E.C.1
Black, C.2
Fleischmajer, R.3
-
26
-
-
0345827523
-
Physiologic responses to hypoxia and implications for hypoxia-inducible factors in the pathogenesis of rheumatoid arthritis
-
Distler JH, Wenger RH, Gassmann M, et al. Physiologic responses to hypoxia and implications for hypoxia-inducible factors in the pathogenesis of rheumatoid arthritis. Arthritis Rheum 2004;50:10-23.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 10-23
-
-
Distler, J.H.1
Wenger, R.H.2
Gassmann, M.3
-
27
-
-
80052453175
-
SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance
-
Niederer F, Ospelt C, Brentano F, et al. SIRT1 overexpression in the rheumatoid arthritis synovium contributes to proinflammatory cytokine production and apoptosis resistance. Ann Rheum Dis 2011;70:1866-73.
-
(2011)
Ann Rheum Dis
, vol.70
, pp. 1866-1873
-
-
Niederer, F.1
Ospelt, C.2
Brentano, F.3
-
28
-
-
33846209989
-
Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis
-
Distler JH, Jungel A, Huber LC, et al. Imatinib mesylate reduces production of extracellular matrix and prevents development of experimental dermal fibrosis. Arthritis Rheum 2007;56:311-22.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 311-322
-
-
Distler, J.H.1
Jungel, A.2
Huber, L.C.3
-
29
-
-
71049129806
-
Identification of a novel microRNA cluster miR-193b-365 in multiple myeloma
-
Unno K, Zhou Y, Zimmerman T, et al. Identification of a novel microRNA cluster miR-193b-365 in multiple myeloma. Leuk Lymphoma 2009; 50:1865-71.
-
(2009)
Leuk Lymphoma
, vol.50
, pp. 1865-1871
-
-
Unno, K.1
Zhou, Y.2
Zimmerman, T.3
-
30
-
-
37149006718
-
Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis
-
Distler JH, Jungel A, Pileckyte M, et al. Hypoxia-induced increase in the production of extracellular matrix proteins in systemic sclerosis. Arthritis Rheum 2007;56:4203-15.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 4203-4215
-
-
Distler, J.H.1
Jungel, A.2
Pileckyte, M.3
-
31
-
-
49949114547
-
Molecular subsets in the gene expression signatures of scleroderma skin
-
Milano A, Pendergrass SA, Sargent JL, et al. Molecular subsets in the gene expression signatures of scleroderma skin. PLoS ONE 2008;3:e2696.
-
(2008)
PLoS ONE
, vol.3
, pp. e2696
-
-
Milano, A.1
Pendergrass, S.A.2
Sargent, J.L.3
-
32
-
-
20444483234
-
Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension
-
McMurtry MS, Archer SL, Altieri DC, et al. Gene therapy targeting survivin selectively induces pulmonary vascular apoptosis and reverses pulmonary arterial hypertension. J Clin Invest 2005;115:1479-91.
-
(2005)
J Clin Invest
, vol.115
, pp. 1479-1491
-
-
McMurtry, M.S.1
Archer, S.L.2
Altieri, D.C.3
-
33
-
-
6344257102
-
Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis
-
McMurtry MS, Bonnet S, Wu X, et al. Dichloroacetate prevents and reverses pulmonary hypertension by inducing pulmonary artery smooth muscle cell apoptosis. Circ Res 2004;95:830-40.
-
(2004)
Circ Res
, vol.95
, pp. 830-840
-
-
McMurtry, M.S.1
Bonnet, S.2
Wu, X.3
-
34
-
-
13444272087
-
Entrez Gene: Gene-centered information at NCBI
-
Maglott D, Ostell J, Pruitt KD, et al. Entrez Gene: gene-centered information at NCBI. Nucleic Acids Res 2005;33:D54-8.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. D54-D58
-
-
Maglott, D.1
Ostell, J.2
Pruitt, K.D.3
-
35
-
-
24944530570
-
The fibrinolytic system components are increased in systemic sclerosis and modulated by Alprostadil (alpha1 ciclodestryn)
-
Bandinelli F, Bartoli F, Perfetto E, et al. The fibrinolytic system components are increased in systemic sclerosis and modulated by Alprostadil (alpha1 ciclodestryn). Clin Exp Rheumatol 2005;23:671-7.
-
(2005)
Clin Exp Rheumatol
, vol.23
, pp. 671-677
-
-
Bandinelli, F.1
Bartoli, F.2
Perfetto, E.3
-
36
-
-
78149269955
-
The plasminogen activator system in fibroblasts from systemic sclerosis
-
Postiglione L, Montuori N, Riccio A, et al. The plasminogen activator system in fibroblasts from systemic sclerosis. Int J Immunopathol Pharmacol 2010;23:891-900.
-
(2010)
Int J Immunopathol Pharmacol
, vol.23
, pp. 891-900
-
-
Postiglione, L.1
Montuori, N.2
Riccio, A.3
-
37
-
-
80055000875
-
MiR-193b regulates Mcl-1 in Melanoma
-
Chen J, Zhang X, Lentz C, et al. miR-193b Regulates Mcl-1 in Melanoma. Am J Pathol 2011;179:2162-8.
-
(2011)
Am J Pathol
, vol.179
, pp. 2162-2168
-
-
Chen, J.1
Zhang, X.2
Lentz, C.3
-
38
-
-
80455166015
-
Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact
-
005322
-
Leivonen SK, Rokka A, Ostling P, et al. Identification of miR-193b targets in breast cancer cells and systems biological analysis of their functional impact. Mol Cell Proteomics 2011;10:M110 005322.
-
(2011)
Mol Cell Proteomics
, vol.10
, pp. M110
-
-
Leivonen, S.K.1
Rokka, A.2
Ostling, P.3
-
39
-
-
70449124422
-
Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer
-
Li XF, Yan PJ, Shao ZM. Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer. Oncogene 2009;28:3937-48.
-
(2009)
Oncogene
, vol.28
, pp. 3937-3948
-
-
Li, X.F.1
Yan, P.J.2
Shao, Z.M.3
-
40
-
-
77955590791
-
MiR-193b is an epigenetically regulated putative tumor suppressor in prostate cancer
-
Rauhala HE, Jalava SE, Isotalo J, et al. miR-193b is an epigenetically regulated putative tumor suppressor in prostate cancer. Int J Cancer 2010;127:1363-72.
-
(2010)
Int J Cancer
, vol.127
, pp. 1363-1372
-
-
Rauhala, H.E.1
Jalava, S.E.2
Isotalo, J.3
-
42
-
-
57749168828
-
MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts
-
Thum T, Gross C, Fiedler J, et al. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature 2008;456:980-4.
-
(2008)
Nature
, vol.456
, pp. 980-984
-
-
Thum, T.1
Gross, C.2
Fiedler, J.3
|