메뉴 건너뛰기




Volumn 6, Issue DEC, 2015, Pages

Natural killer cell immunomodulation: Targeting activating, inhibitory, and co-stimulatory receptor signaling for cancer immunotherapy

Author keywords

Adoptive cell therapy; Cancer vaccines; Checkpoint blockade; Immunotherapy; Monoclonal antibody; Natural killer cells

Indexed keywords

CANCER EPIDEMIOLOGY; CANCER IMMUNOTHERAPY; CELL ACTIVATION; CELL INTERACTION; CELL PROLIFERATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOSURVEILLANCE; LYSIS; NATURAL KILLER CELL; TRANSFORMED CELL; TUMOR ESCAPE;

EID: 84954202043     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2015.00601     Document Type: Review
Times cited : (146)

References (109)
  • 1
    • 53549114206 scopus 로고    scopus 로고
    • NK cells and cancer immunosurveillance
    • Waldhauer I, Steinle A. NK cells and cancer immunosurveillance. Oncogene (2008) 27:5932-43. doi: 10.1038/onc.2008.267.
    • (2008) Oncogene , vol.27 , pp. 5932-5943
    • Waldhauer, I.1    Steinle, A.2
  • 3
    • 50949124847 scopus 로고    scopus 로고
    • Human natural killer cells
    • Caligiuri MA. Human natural killer cells. Blood (2008) 112:461-9. doi:10.1182/blood-2007-09-077438.
    • (2008) Blood , vol.112 , pp. 461-469
    • Caligiuri, M.A.1
  • 4
    • 0035874522 scopus 로고    scopus 로고
    • Human natural killer cells: a unique innate immunoregulatory role for the CD56bright subset
    • Cooper MA, Fehniger TA, Turner SC, Chen KS, Ghaheri BA, Ghayur T, et al. Human natural killer cells: a unique innate immunoregulatory role for the CD56bright subset. Blood (2001) 97:3146-51. doi:10.1182/blood.V97.10.3146.
    • (2001) Blood , vol.97 , pp. 3146-3151
    • Cooper, M.A.1    Fehniger, T.A.2    Turner, S.C.3    Chen, K.S.4    Ghaheri, B.A.5    Ghayur, T.6
  • 5
    • 34250802584 scopus 로고    scopus 로고
    • CD56bright human NK cells differentiate into CD56dim cells: role of contact with peripheral fibroblasts
    • Chan A, Hong DL, Atzberger A, Kollnberger S, Filer AD, Buckley CD, et al. CD56bright human NK cells differentiate into CD56dim cells: role of contact with peripheral fibroblasts. J Immunol (2007) 179:89-94. doi:10.4049/jimmunol.179.1.89.
    • (2007) J Immunol , vol.179 , pp. 89-94
    • Chan, A.1    Hong, D.L.2    Atzberger, A.3    Kollnberger, S.4    Filer, A.D.5    Buckley, C.D.6
  • 6
    • 34247150402 scopus 로고    scopus 로고
    • CD56brightCD16- killer Ig-like receptor- NK cells display longer telomeres and acquire features of CD56dim NK cells upon activation
    • Romagnani C, Juelke K, Falco M, Morandi B, D'Agostino A, Costa R, et al. CD56brightCD16- killer Ig-like receptor- NK cells display longer telomeres and acquire features of CD56dim NK cells upon activation. J Immunol (2007) 178:4947-55. doi:10.4049/jimmunol.178.8.4947.
    • (2007) J Immunol , vol.178 , pp. 4947-4955
    • Romagnani, C.1    Juelke, K.2    Falco, M.3    Morandi, B.4    D'Agostino, A.5    Costa, R.6
  • 7
    • 79551666576 scopus 로고    scopus 로고
    • Revisiting human natural killer cell subset function revealed cytolytic CD56(dim)CD16+ NK cells as rapid producers of abundant IFN-gamma on activation
    • De Maria A, Bozzano F, Cantoni C, Moretta L. Revisiting human natural killer cell subset function revealed cytolytic CD56(dim)CD16+ NK cells as rapid producers of abundant IFN-gamma on activation. Proc Natl Acad Sci U S A (2011) 108:728-32. doi:10.1073/pnas.1012356108.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 728-732
    • De Maria, A.1    Bozzano, F.2    Cantoni, C.3    Moretta, L.4
  • 8
    • 34247595404 scopus 로고    scopus 로고
    • Prospects for the use of NK cells in immunotherapy of human cancer
    • Ljunggren HG, Malmberg KJ. Prospects for the use of NK cells in immunotherapy of human cancer. Nat Rev Immunol (2007) 7:329-39. doi:10.1038/nri2073.
    • (2007) Nat Rev Immunol , vol.7 , pp. 329-339
    • Ljunggren, H.G.1    Malmberg, K.J.2
  • 9
    • 79951824956 scopus 로고    scopus 로고
    • Natural killer cells are scarce in colorectal carcinoma tissue despite high levels of chemokines and cytokines
    • Halama N, Braun M, Kahlert C, Spille A, Quack C, Rahbari N, et al. Natural killer cells are scarce in colorectal carcinoma tissue despite high levels of chemokines and cytokines. Clin Cancer Res (2011) 17:678-89. doi:10.1158/1078-0432.CCR-10-2173.
    • (2011) Clin Cancer Res , vol.17 , pp. 678-689
    • Halama, N.1    Braun, M.2    Kahlert, C.3    Spille, A.4    Quack, C.5    Rahbari, N.6
  • 10
    • 84857372947 scopus 로고    scopus 로고
    • Transcript signature predicts tissue NK cell content and defines renal cell carcinoma subgroups independent of TNM staging
    • Eckl J, Buchner A, Prinz PU, Riesenberg R, Siegert SI, Kammerer R, et al. Transcript signature predicts tissue NK cell content and defines renal cell carcinoma subgroups independent of TNM staging. J Mol Med (Berl) (2012) 90:55-66. doi:10.1007/s00109-011-0806-7.
    • (2012) J Mol Med (Berl) , vol.90 , pp. 55-66
    • Eckl, J.1    Buchner, A.2    Prinz, P.U.3    Riesenberg, R.4    Siegert, S.I.5    Kammerer, R.6
  • 11
    • 80051675837 scopus 로고    scopus 로고
    • Profound coordinated alterations of intratumoral NK cell phenotype and function in lung carcinoma
    • Platonova S, Cherfils-Vicini J, Damotte D, Crozet L, Vieillard V, Validire P, et al. Profound coordinated alterations of intratumoral NK cell phenotype and function in lung carcinoma. Cancer Res (2011) 71:5412-22. doi:10.1158/0008-5472.CAN-10-4179.
    • (2011) Cancer Res , vol.71 , pp. 5412-5422
    • Platonova, S.1    Cherfils-Vicini, J.2    Damotte, D.3    Crozet, L.4    Vieillard, V.5    Validire, P.6
  • 12
    • 0034715948 scopus 로고    scopus 로고
    • Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population
    • Imai K, Matsuyama S, Miyake S, Suga K, Nakachi K. Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population. Lancet (2000) 356:1795-9. doi:10.1016/S0140-6736(00)03231-1.
    • (2000) Lancet , vol.356 , pp. 1795-1799
    • Imai, K.1    Matsuyama, S.2    Miyake, S.3    Suga, K.4    Nakachi, K.5
  • 13
    • 39049191354 scopus 로고    scopus 로고
    • The first molecular basis of the "missing self" hypothesis
    • Borrego F. The first molecular basis of the "missing self" hypothesis. J Immunol (2006) 177:5759-60. doi:10.4049/jimmunol.177.9.5759.
    • (2006) J Immunol , vol.177 , pp. 5759-5760
    • Borrego, F.1
  • 14
    • 23044478500 scopus 로고    scopus 로고
    • Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. 1986
    • Kärre K, Ljunggren HG, Piontek G, Kiessling R. Selective rejection of H-2-deficient lymphoma variants suggests alternative immune defence strategy. 1986. J Immunol (2005) 174:6566-9. doi:10.1038/319675a0.
    • (2005) J Immunol , vol.174 , pp. 6566-6569
    • Kärre, K.1    Ljunggren, H.G.2    Piontek, G.3    Kiessling, R.4
  • 15
    • 0026628008 scopus 로고
    • MHC class I alloantigen specificity of
    • Karlhofer FM, Ribaudo RK, Yokoyama WM. MHC class I alloantigen specificity of. Ly-49 (1992) 358:66-70. doi:10.1038/358066a0.
    • (1992) Ly-49 , vol.358 , pp. 66-70
    • Karlhofer, F.M.1    Ribaudo, R.K.2    Yokoyama, W.M.3
  • 16
    • 44949266455 scopus 로고
    • In search of the missing self: MHC molecules and NK cell recognition
    • Ljunggren HG, Kärre K. In search of the missing self: MHC molecules and NK cell recognition. Immunol Today (1990) 11:237-44. doi:10.1016/0167-5699(90)90097-S.
    • (1990) Immunol Today , vol.11 , pp. 237-244
    • Ljunggren, H.G.1    Kärre, K.2
  • 17
    • 84875528678 scopus 로고    scopus 로고
    • Controlling natural killer cell responses: integration of signals for activation and inhibition
    • Long EO, Kim HS, Liu D, Peterson ME, Rajagopalan S. Controlling natural killer cell responses: integration of signals for activation and inhibition. Annu Rev Immunol (2013) 31:227-58. doi:10.1146/annurev-immunol-020711-075005.
    • (2013) Annu Rev Immunol , vol.31 , pp. 227-258
    • Long, E.O.1    Kim, H.S.2    Liu, D.3    Peterson, M.E.4    Rajagopalan, S.5
  • 18
    • 0141741403 scopus 로고    scopus 로고
    • Lytic granules, secretory lysosomes and disease
    • Clark R, Griffiths GM. Lytic granules, secretory lysosomes and disease. Curr Opin Immunol (2003) 15:516-21. doi:10.1016/S0952-7915(03)00113-4.
    • (2003) Curr Opin Immunol , vol.15 , pp. 516-521
    • Clark, R.1    Griffiths, G.M.2
  • 19
    • 0038725690 scopus 로고    scopus 로고
    • The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal
    • Lieberman J. The ABCs of granule-mediated cytotoxicity: new weapons in the arsenal. Nat Rev Immunol (2003) 3:361-70. doi:10.1038/nri1083.
    • (2003) Nat Rev Immunol , vol.3 , pp. 361-370
    • Lieberman, J.1
  • 20
    • 80052035441 scopus 로고    scopus 로고
    • Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells
    • Thiery J, Keefe D, Boulant S, Boucrot E, Walch M, Martinvalet D, et al. Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells. Nat Immunol (2011) 12:770-7. doi:10.1038/ni.2050.
    • (2011) Nat Immunol , vol.12 , pp. 770-777
    • Thiery, J.1    Keefe, D.2    Boulant, S.3    Boucrot, E.4    Walch, M.5    Martinvalet, D.6
  • 21
    • 77954197189 scopus 로고    scopus 로고
    • Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment
    • Mentlik AN, Sanborn KB, Holzbaur EL, Orange JS. Rapid lytic granule convergence to the MTOC in natural killer cells is dependent on dynein but not cytolytic commitment. Mol Biol Cell (2010) 21:2241-56. doi:10.1091/mbc.E09-11-0930.
    • (2010) Mol Biol Cell , vol.21 , pp. 2241-2256
    • Mentlik, A.N.1    Sanborn, K.B.2    Holzbaur, E.L.3    Orange, J.S.4
  • 22
    • 77951681958 scopus 로고    scopus 로고
    • Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B
    • Afonina IS, Cullen SP, Martin SJ. Cytotoxic and non-cytotoxic roles of the CTL/NK protease granzyme B. Immunol Rev (2010) 235:105-16. doi:10.1111/j.0105-2896.2010.00908.x.
    • (2010) Immunol Rev , vol.235 , pp. 105-116
    • Afonina, I.S.1    Cullen, S.P.2    Martin, S.J.3
  • 23
    • 0036005884 scopus 로고    scopus 로고
    • The roles of IFNγ in protection against tumor development and cancer immunoediting
    • Ikeda H, Old LJ, Schreiber RD. The roles of IFNγ in protection against tumor development and cancer immunoediting. Cytokine Growth Factor Rev (2002) 13:95-109. doi:10.1016/S1359-6101(01)00038-7.
    • (2002) Cytokine Growth Factor Rev , vol.13 , pp. 95-109
    • Ikeda, H.1    Old, L.J.2    Schreiber, R.D.3
  • 24
    • 67349162130 scopus 로고    scopus 로고
    • Tumour necrosis factor and cancer
    • Balkwill F. Tumour necrosis factor and cancer. Nat Rev Cancer (2009) 9:361-71. doi:10.1038/nrc2628.
    • (2009) Nat Rev Cancer , vol.9 , pp. 361-371
    • Balkwill, F.1
  • 25
    • 0031081260 scopus 로고    scopus 로고
    • Membrane tumor necrosis factor-alpha (TNF-alpha) expressed on HTLV-I-infected T cells mediates a costimulatory signal for B cell activation - characterization of membrane TNF-alpha
    • Higuchi M, Nagasawa K, Horiuchi T, Oike M, Ito Y, Yasukawa M, et al. Membrane tumor necrosis factor-alpha (TNF-alpha) expressed on HTLV-I-infected T cells mediates a costimulatory signal for B cell activation - characterization of membrane TNF-alpha. Clin Immunol Immunopathol (1997) 82:133-40. doi:10.1006/clin.1996.4291.
    • (1997) Clin Immunol Immunopathol , vol.82 , pp. 133-140
    • Higuchi, M.1    Nagasawa, K.2    Horiuchi, T.3    Oike, M.4    Ito, Y.5    Yasukawa, M.6
  • 26
    • 0022548587 scopus 로고
    • Identity of differentiation inducing factor and tumour necrosis factor
    • Takeda K, Iwamoto S, Sugimoto H, Takuma T, Kawatani N, Noda M, et al. Identity of differentiation inducing factor and tumour necrosis factor. Nature (1986) 323:338-40. doi:10.1038/323338a0.
    • (1986) Nature , vol.323 , pp. 338-340
    • Takeda, K.1    Iwamoto, S.2    Sugimoto, H.3    Takuma, T.4    Kawatani, N.5    Noda, M.6
  • 28
    • 84864131126 scopus 로고    scopus 로고
    • Fc gamma receptor polymorphisms as predictive markers of cetuximab efficacy in epidermal growth factor receptor downstream-mutated metastatic colorectal cancer
    • Rodríguez J, Zarate R, Bandres E, Boni V, Hernández A, Sola JJ, et al. Fc gamma receptor polymorphisms as predictive markers of cetuximab efficacy in epidermal growth factor receptor downstream-mutated metastatic colorectal cancer. Eur J Cancer (2012) 48:1774-80. doi:10.1016/j.ejca.2012.01.007.
    • (2012) Eur J Cancer , vol.48 , pp. 1774-1780
    • Rodríguez, J.1    Zarate, R.2    Bandres, E.3    Boni, V.4    Hernández, A.5    Sola, J.J.6
  • 29
    • 0036464719 scopus 로고    scopus 로고
    • Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene
    • Cartron G, Dacheux L, Salles G, Solal-Celigny P, Bardos P, Colombat P, et al. Therapeutic activity of humanized anti-CD20 monoclonal antibody and polymorphism in IgG Fc receptor FcgammaRIIIa gene. Blood (2002) 99:754-8. doi:10.1182/blood.V99.3.754.
    • (2002) Blood , vol.99 , pp. 754-758
    • Cartron, G.1    Dacheux, L.2    Salles, G.3    Solal-Celigny, P.4    Bardos, P.5    Colombat, P.6
  • 30
    • 42949157368 scopus 로고    scopus 로고
    • Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer
    • Musolino A, Naldi N, Bortesi B, Pezzuolo D, Capelletti M, Missale G, et al. Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer. J Clin Oncol (2008) 26:1789-96. doi:10.1200/JCO.2007.14.8957.
    • (2008) J Clin Oncol , vol.26 , pp. 1789-1796
    • Musolino, A.1    Naldi, N.2    Bortesi, B.3    Pezzuolo, D.4    Capelletti, M.5    Missale, G.6
  • 31
    • 84969565501 scopus 로고    scopus 로고
    • Enhancement of antibody-dependent cell mediated cytotoxicity: a new era in cancer treatment
    • Rajasekaran N, Chester C, Yonezawa A, Zhao X, et al. Enhancement of antibody-dependent cell mediated cytotoxicity: a new era in cancer treatment. Biologics (2015) 9:35-43. doi:10.2147/ITT.S61292.
    • (2015) Biologics , vol.9 , pp. 35-43
    • Rajasekaran, N.1    Chester, C.2    Yonezawa, A.3    Zhao, X.4
  • 32
    • 77954144904 scopus 로고    scopus 로고
    • CD16 cross-linking induces increased expression of CD56 and production of IL-12 in peripheral NK cells
    • Márquez ME, Millet C, Stekman H, Conesa A, Deglesne PA, Toro F, et al. CD16 cross-linking induces increased expression of CD56 and production of IL-12 in peripheral NK cells. Cell Immunol (2010) 264:86-92. doi:10.1016/j.cellimm.2010.05.002.
    • (2010) Cell Immunol , vol.264 , pp. 86-92
    • Márquez, M.E.1    Millet, C.2    Stekman, H.3    Conesa, A.4    Deglesne, P.A.5    Toro, F.6
  • 33
    • 24144476967 scopus 로고    scopus 로고
    • Natural killer cell-dendritic cell crosstalk in the initiation of immune responses
    • Walzer T, Dalod M, Vivier E, Zitvogel L. Natural killer cell-dendritic cell crosstalk in the initiation of immune responses. Expert Opin Biol Ther (2005) 5(Suppl 1):S49-59. doi:10.1517/14712598.5.1.S49.
    • (2005) Expert Opin Biol Ther , vol.5 , pp. S49-59
    • Walzer, T.1    Dalod, M.2    Vivier, E.3    Zitvogel, L.4
  • 34
    • 0028294895 scopus 로고
    • The binding and lysis of target cells by cytotoxic lymphocytes: molecular and cellular aspects
    • Berke G. The binding and lysis of target cells by cytotoxic lymphocytes: molecular and cellular aspects. Annu Rev Immunol (1994) 12:735-73. doi:10.1146/annurev.iy.12.040194.003511.
    • (1994) Annu Rev Immunol , vol.12 , pp. 735-773
    • Berke, G.1
  • 35
    • 0032447111 scopus 로고    scopus 로고
    • Natural killer (NK) cell-mediated cytotoxicity: differential use of TRAIL and Fas ligand by immature and mature primary human NK cells
    • Zamai L, Ahmad M, Bennett IM, Azzoni L, Alnemri ES, Perussia B. Natural killer (NK) cell-mediated cytotoxicity: differential use of TRAIL and Fas ligand by immature and mature primary human NK cells. J Exp Med (1998) 188:2375-80. doi:10.1084/jem.188.12.2375.
    • (1998) J Exp Med , vol.188 , pp. 2375-2380
    • Zamai, L.1    Ahmad, M.2    Bennett, I.M.3    Azzoni, L.4    Alnemri, E.S.5    Perussia, B.6
  • 37
    • 0015383455 scopus 로고
    • Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
    • Kerr JF, Wyllie AH, Currie AR. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer (1972) 26:239-57. doi:10.1038/bjc.1972.33.
    • (1972) Br J Cancer , vol.26 , pp. 239-257
    • Kerr, J.F.1    Wyllie, A.H.2    Currie, A.R.3
  • 38
    • 0036377840 scopus 로고    scopus 로고
    • The biological role of the Fas/FasL system during tumor formation and progression
    • Reichmann E. The biological role of the Fas/FasL system during tumor formation and progression. Semin Cancer Biol (2002) 12:309-15. doi:10.1016/S1044-579X(02)00017-2.
    • (2002) Semin Cancer Biol , vol.12 , pp. 309-315
    • Reichmann, E.1
  • 39
    • 0035137696 scopus 로고    scopus 로고
    • Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells
    • Takeda K, Hayakawa Y, Smyth MJ, Kayagaki N, Yamaguchi N, Kakuta S, et al. Involvement of tumor necrosis factor-related apoptosis-inducing ligand in surveillance of tumor metastasis by liver natural killer cells. Nat Med (2001) 7:94-100. doi:10.1038/83416.
    • (2001) Nat Med , vol.7 , pp. 94-100
    • Takeda, K.1    Hayakawa, Y.2    Smyth, M.J.3    Kayagaki, N.4    Yamaguchi, N.5    Kakuta, S.6
  • 40
    • 9144234147 scopus 로고    scopus 로고
    • TRAIL and its receptors as targets for cancer therapy
    • Yagita H, Takeda K, Hayakawa Y, Smyth MJ, Okumura K. TRAIL and its receptors as targets for cancer therapy. Cancer Sci (2004) 95:777-83. doi:10.1111/j.1349-7006.2004.tb02181.x.
    • (2004) Cancer Sci , vol.95 , pp. 777-783
    • Yagita, H.1    Takeda, K.2    Hayakawa, Y.3    Smyth, M.J.4    Okumura, K.5
  • 42
    • 52649109068 scopus 로고    scopus 로고
    • The TRAIL apoptotic pathway in cancer onset, progression and therapy
    • Johnstone RW, Frew AJ, Smyth MJ. The TRAIL apoptotic pathway in cancer onset, progression and therapy. Nat Rev Cancer (2008) 8:782-98. doi:10.1038/nrc2465.
    • (2008) Nat Rev Cancer , vol.8 , pp. 782-798
    • Johnstone, R.W.1    Frew, A.J.2    Smyth, M.J.3
  • 43
    • 84937974581 scopus 로고    scopus 로고
    • Immunotherapy with liposome-bound TRAIL overcomes partial protection to soluble TRAIL-induced apoptosis offered by down-regulation of Bim in leukemic cells
    • De Miguel D, Gallego-Lleyda A, Galan-Malo P, Rodriguez-Vigil C, Marzo I, Anel A, et al. Immunotherapy with liposome-bound TRAIL overcomes partial protection to soluble TRAIL-induced apoptosis offered by down-regulation of Bim in leukemic cells. Clin Transl Oncol (2015) 17:657-67. doi:10.1007/s12094-015-1295-x.
    • (2015) Clin Transl Oncol , vol.17 , pp. 657-667
    • De Miguel, D.1    Gallego-Lleyda, A.2    Galan-Malo, P.3    Rodriguez-Vigil, C.4    Marzo, I.5    Anel, A.6
  • 44
    • 84875230886 scopus 로고    scopus 로고
    • On the TRAIL to successful cancer therapy? predicting and counteracting resistance against TRAIL-based therapeutics
    • Dimberg LY, Anderson CK, Camidge R, Behbakht K, Thorburn A, Ford HL. On the TRAIL to successful cancer therapy? predicting and counteracting resistance against TRAIL-based therapeutics. Oncogene (2013) 32:1341-50. doi:10.1038/onc.2012.164.
    • (2013) Oncogene , vol.32 , pp. 1341-1350
    • Dimberg, L.Y.1    Anderson, C.K.2    Camidge, R.3    Behbakht, K.4    Thorburn, A.5    Ford, H.L.6
  • 45
    • 84860540844 scopus 로고    scopus 로고
    • The interaction of NK cells and dendritic cells in the tumor environment: how to enforce NK cell & DC action under immunosuppressive conditions?
    • Jacobs B, Ullrich E. The interaction of NK cells and dendritic cells in the tumor environment: how to enforce NK cell & DC action under immunosuppressive conditions? Curr Med Chem (2012) 19:1771-9. doi:10.2174/092986712800099857.
    • (2012) Curr Med Chem , vol.19 , pp. 1771-1779
    • Jacobs, B.1    Ullrich, E.2
  • 46
    • 80054729324 scopus 로고    scopus 로고
    • B7-H6/NKp30 interaction: a mechanism of alerting NK cells against tumors
    • Kaifu T, Escalière B, Gastinel LN, Vivier E, Baratin M. B7-H6/NKp30 interaction: a mechanism of alerting NK cells against tumors. Cell Mol Life Sci (2011) 68:3531-9. doi:10.1007/s00018-011-0802-7.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 3531-3539
    • Kaifu, T.1    Escalière, B.2    Gastinel, L.N.3    Vivier, E.4    Baratin, M.5
  • 47
    • 68849105814 scopus 로고    scopus 로고
    • Oncogenic stress sensed by the immune system: role of natural killer cell receptors
    • Raulet DH, Guerra N. Oncogenic stress sensed by the immune system: role of natural killer cell receptors. Nat Rev Immunol (2009) 9:568-80. doi:10.1038/nri2604.
    • (2009) Nat Rev Immunol , vol.9 , pp. 568-580
    • Raulet, D.H.1    Guerra, N.2
  • 48
    • 84877044329 scopus 로고    scopus 로고
    • Natural cytotoxicity receptors: broader expression patterns and functions in innate and adaptive immune cells
    • Hudspeth K, Silva-Santos B, Mavilio D. Natural cytotoxicity receptors: broader expression patterns and functions in innate and adaptive immune cells. Front Immunol (2013) 4:69. doi:10.3389/fimmu.2013.00069.
    • (2013) Front Immunol , vol.4 , pp. 69
    • Hudspeth, K.1    Silva-Santos, B.2    Mavilio, D.3
  • 49
    • 0348013081 scopus 로고    scopus 로고
    • IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptors
    • Sivori S, Cantoni C, Parolini S, Marcenaro E, Conte R, Moretta L, et al. IL-21 induces both rapid maturation of human CD34+ cell precursors towards NK cells and acquisition of surface killer Ig-like receptors. Eur J Immunol (2003) 33:3439-47. doi:10.1002/eji.200324533.
    • (2003) Eur J Immunol , vol.33 , pp. 3439-3447
    • Sivori, S.1    Cantoni, C.2    Parolini, S.3    Marcenaro, E.4    Conte, R.5    Moretta, L.6
  • 50
    • 0035059950 scopus 로고    scopus 로고
    • Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis
    • Moretta A, Bottino C, Vitale M, Pende D, Cantoni C, Mingari MC, et al. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu Rev Immunol (2001) 19:197-223. doi:10.1146/annurev.immunol.19.1.197.
    • (2001) Annu Rev Immunol , vol.19 , pp. 197-223
    • Moretta, A.1    Bottino, C.2    Vitale, M.3    Pende, D.4    Cantoni, C.5    Mingari, M.C.6
  • 51
    • 84988254386 scopus 로고    scopus 로고
    • Identification of NKp80, a novel triggering molecule expressed by human NK cells
    • Vitale M, Falco M, Castriconi R, Parolini S, Zambello R, Semenzato G, et al. Identification of NKp80, a novel triggering molecule expressed by human NK cells. Eur J Immunol (2001) 31:233-42. doi:10.1002/1521-4141(200101)31:1<233::AID-IMMU233>3.3.CO;2-W.
    • (2001) Eur J Immunol , vol.31 , pp. 233-242
    • Vitale, M.1    Falco, M.2    Castriconi, R.3    Parolini, S.4    Zambello, R.5    Semenzato, G.6
  • 52
    • 67650267743 scopus 로고    scopus 로고
    • Low NKp30, NKp46 and NKG2D expression and reduced cytotoxic activity on NK cells in cervical cancer and precursor lesions
    • Garcia-Iglesias T, Del Toro-Arreola A, Albarran-Somoza B, Del Toro-Arreola S. Low NKp30, NKp46 and NKG2D expression and reduced cytotoxic activity on NK cells in cervical cancer and precursor lesions. BMC Cancer (2009) 9:186. doi:10.1186/1471-2407-9-186.
    • (2009) BMC Cancer , vol.9 , pp. 186
    • Garcia-Iglesias, T.1    Del Toro-Arreola, A.2    Albarran-Somoza, B.3    Del Toro-Arreola, S.4
  • 53
    • 84868587481 scopus 로고    scopus 로고
    • Mimicking an induced self phenotype by coating lymphomas with the NKp30 ligand B7-H6 promotes NK cell cytotoxicity
    • Kellner C, Maurer T, Hallack D, Repp R, van de Winkel JG, Parren PW, et al. Mimicking an induced self phenotype by coating lymphomas with the NKp30 ligand B7-H6 promotes NK cell cytotoxicity. J Immunol (2012) 189:5037-46. doi:10.4049/jimmunol.1201321.
    • (2012) J Immunol , vol.189 , pp. 5037-5046
    • Kellner, C.1    Maurer, T.2    Hallack, D.3    Repp, R.4    van de Winkel, J.G.5    Parren, P.W.6
  • 54
    • 79958118266 scopus 로고    scopus 로고
    • Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors
    • Delahaye NF, Rusakiewicz S, Martins I, Ménard C, Roux S, Lyonnet L, et al. Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors. Nat Med (2011) 17:700-7. doi:10.1038/nm.2366.
    • (2011) Nat Med , vol.17 , pp. 700-707
    • Delahaye, N.F.1    Rusakiewicz, S.2    Martins, I.3    Ménard, C.4    Roux, S.5    Lyonnet, L.6
  • 56
    • 84875509728 scopus 로고    scopus 로고
    • Regulation of ligands for the NKG2D activating receptor
    • Raulet DH, Gasser S, Gowen BG, Deng W, Jung H. Regulation of ligands for the NKG2D activating receptor. Annu Rev Immunol (2013) 31:413. doi:10.1146/annurev-immunol-032712-095951.
    • (2013) Annu Rev Immunol , vol.31 , pp. 413
    • Raulet, D.H.1    Gasser, S.2    Gowen, B.G.3    Deng, W.4    Jung, H.5
  • 57
    • 84961879643 scopus 로고    scopus 로고
    • NKG2D receptor and its ligands in host defense
    • Lanier LL. NKG2D receptor and its ligands in host defense. Cancer Immunol Res (2015) 3:575-82. doi:10.1158/2326-6066.CIR-15-0098.
    • (2015) Cancer Immunol Res , vol.3 , pp. 575-582
    • Lanier, L.L.1
  • 58
    • 67349195728 scopus 로고    scopus 로고
    • A possible mechanism of intravesical BCG therapy for human bladder carcinoma: involvement of innate effector cells for the inhibition of tumor growth
    • Higuchi T, Shimizu M, Owaki A, Takahashi M, Shinya E, Nishimura T, et al. A possible mechanism of intravesical BCG therapy for human bladder carcinoma: involvement of innate effector cells for the inhibition of tumor growth. Cancer Immunol Immunother (2009) 58:1245-55. doi:10.1007/s00262-008-0643-x.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1245-1255
    • Higuchi, T.1    Shimizu, M.2    Owaki, A.3    Takahashi, M.4    Shinya, E.5    Nishimura, T.6
  • 59
    • 84935065126 scopus 로고    scopus 로고
    • NKG2D is a key receptor for recognition of bladder cancer cells by IL-2-activated NK cells and BCG promotes NK cell activation
    • García-Cuesta EM, López-Cobo S, álvarez-Maestro M, Esteso G, Romera-Cárdenas G, Rey M, et al. NKG2D is a key receptor for recognition of bladder cancer cells by IL-2-activated NK cells and BCG promotes NK cell activation. Front Immunol (2015) 6:284. doi:10.3389/fimmu.2015.00284.
    • (2015) Front Immunol , vol.6 , pp. 284
    • García-Cuesta, E.M.1    López-Cobo, S.2    álvarez-Maestro, M.3    Esteso, G.4    Romera-Cárdenas, G.5    Rey, M.6
  • 60
    • 0037126310 scopus 로고    scopus 로고
    • Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation
    • Groh V, Wu J, Yee C, Spies T. Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation. Nature (2002) 419:734-8. doi:10.1038/nature01112.
    • (2002) Nature , vol.419 , pp. 734-738
    • Groh, V.1    Wu, J.2    Yee, C.3    Spies, T.4
  • 61
    • 34249295619 scopus 로고    scopus 로고
    • Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands
    • Kaiser BK, Yim D, Chow IT, Gonzalez S, Dai Z, Mann HH, et al. Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands. Nature (2007) 447:482-6. doi:10.1038/nature05768.
    • (2007) Nature , vol.447 , pp. 482-486
    • Kaiser, B.K.1    Yim, D.2    Chow, I.T.3    Gonzalez, S.4    Dai, Z.5    Mann, H.H.6
  • 62
    • 84927658788 scopus 로고    scopus 로고
    • Antitumor immunity. A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection
    • Deng W, Gowen BG, Zhang L, Wang L, Lau S, Iannello A, et al. Antitumor immunity. A shed NKG2D ligand that promotes natural killer cell activation and tumor rejection. Science (2015) 348:136-9. doi:10.1126/science.1258867.
    • (2015) Science , vol.348 , pp. 136-139
    • Deng, W.1    Gowen, B.G.2    Zhang, L.3    Wang, L.4    Lau, S.5    Iannello, A.6
  • 63
    • 0027244760 scopus 로고
    • A novel function-associated molecule related to non-MHC-restricted cytotoxicity mediated by activated natural killer cells and T cells
    • Garni-Wagner BA, Purohit A, Mathew PA, Bennett M, Kumar V. A novel function-associated molecule related to non-MHC-restricted cytotoxicity mediated by activated natural killer cells and T cells. J Immunol (1993) 151:60-70.
    • (1993) J Immunol , vol.151 , pp. 60-70
    • Garni-Wagner, B.A.1    Purohit, A.2    Mathew, P.A.3    Bennett, M.4    Kumar, V.5
  • 64
    • 0032956398 scopus 로고    scopus 로고
    • Activating interactions in human NK cell recognition: the role of 2B4-CD48
    • Nakajima H, Cella M, Langen H, Friedlein A, Colonna M. Activating interactions in human NK cell recognition: the role of 2B4-CD48. Eur J Immunol (1999) 29:1676-83. doi:10.1002/(SICI)1521-4141(199905)29:05<1676::AID-IMMU1676>3.0.CO;2-Y.
    • (1999) Eur J Immunol , vol.29 , pp. 1676-1683
    • Nakajima, H.1    Cella, M.2    Langen, H.3    Friedlein, A.4    Colonna, M.5
  • 65
    • 30144443832 scopus 로고    scopus 로고
    • Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion
    • Bryceson YT, March ME, Ljunggren HG, Long EO. Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion. Blood (2006) 107:159-66. doi:10.1182/blood-2005-04-1351.
    • (2006) Blood , vol.107 , pp. 159-166
    • Bryceson, Y.T.1    March, M.E.2    Ljunggren, H.G.3    Long, E.O.4
  • 66
    • 84898969025 scopus 로고    scopus 로고
    • DNAM-1 control of natural killer cells functions through nectin and nectin-like proteins
    • de Andrade LF, Smyth MJ, Martinet L. DNAM-1 control of natural killer cells functions through nectin and nectin-like proteins. Immunol Cell Biol (2014) 92:237-44. doi:10.1038/icb.2013.95.
    • (2014) Immunol Cell Biol , vol.92 , pp. 237-244
    • de Andrade, L.F.1    Smyth, M.J.2    Martinet, L.3
  • 67
    • 15844375309 scopus 로고    scopus 로고
    • DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes
    • Shibuya A, Campbell D, Hannum C, Yssel H, Franz-Bacon K, McClanahan T, et al. DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. Immunity (1996) 4:573-81. doi:10.1016/S1074-7613(00)70060-4.
    • (1996) Immunity , vol.4 , pp. 573-581
    • Shibuya, A.1    Campbell, D.2    Hannum, C.3    Yssel, H.4    Franz-Bacon, K.5    McClanahan, T.6
  • 68
    • 4444377459 scopus 로고    scopus 로고
    • Biology and pathology of nectins and nectin-like molecules
    • Sakisaka T, Takai Y. Biology and pathology of nectins and nectin-like molecules. Curr Opin Cell Biol (2004) 16:513-21. doi:10.1016/j.ceb.2004.07.007.
    • (2004) Curr Opin Cell Biol , vol.16 , pp. 513-521
    • Sakisaka, T.1    Takai, Y.2
  • 69
    • 32644448125 scopus 로고    scopus 로고
    • Tumor rejection by the poliovirus receptor family ligands of the DNAM-1 (CD226) receptor
    • Tahara-Hanaoka S, Shibuya K, Kai H, Miyamoto A, Morikawa Y, Ohkochi N, et al. Tumor rejection by the poliovirus receptor family ligands of the DNAM-1 (CD226) receptor. Blood (2006) 107:1491-6. doi:10.1182/blood-2005-04-1684.
    • (2006) Blood , vol.107 , pp. 1491-1496
    • Tahara-Hanaoka, S.1    Shibuya, K.2    Kai, H.3    Miyamoto, A.4    Morikawa, Y.5    Ohkochi, N.6
  • 70
    • 10844246498 scopus 로고    scopus 로고
    • Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: critical role of DNAX accessory molecule-1-poliovirus receptor interaction
    • Castriconi R, Dondero A, Corrias MV, Lanino E, Pende D, Moretta L, et al. Natural killer cell-mediated killing of freshly isolated neuroblastoma cells: critical role of DNAX accessory molecule-1-poliovirus receptor interaction. Cancer Res (2004) 64:9180-4. doi:10.1158/0008-5472.CAN-04-2682.
    • (2004) Cancer Res , vol.64 , pp. 9180-9184
    • Castriconi, R.1    Dondero, A.2    Corrias, M.V.3    Lanino, E.4    Pende, D.5    Moretta, L.6
  • 71
    • 77954107953 scopus 로고    scopus 로고
    • Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells
    • Carlsten M, Norell H, Bryceson YT, Poschke I, Schedvins K, Ljunggren HG, et al. Primary human tumor cells expressing CD155 impair tumor targeting by down-regulating DNAM-1 on NK cells. J Immunol (2009) 183:4921-30. doi:10.4049/jimmunol.0901226.
    • (2009) J Immunol , vol.183 , pp. 4921-4930
    • Carlsten, M.1    Norell, H.2    Bryceson, Y.T.3    Poschke, I.4    Schedvins, K.5    Ljunggren, H.G.6
  • 73
    • 65349119978 scopus 로고    scopus 로고
    • CD28 and CTLA-4 coreceptor expression and signal transduction
    • Rudd CE, Taylor A, Schneider H. CD28 and CTLA-4 coreceptor expression and signal transduction. Immunol Rev (2009) 229:12-26. doi:10.1111/j.1600-065X.2009.00770.x.
    • (2009) Immunol Rev , vol.229 , pp. 12-26
    • Rudd, C.E.1    Taylor, A.2    Schneider, H.3
  • 74
    • 42649125225 scopus 로고    scopus 로고
    • PD-1 and its ligands in tolerance and immunity
    • Keir ME, Butte MJ, Freeman GJ, Sharpe AH. PD-1 and its ligands in tolerance and immunity. Annu Rev Immunol (2008) 26:677-704. doi:10.1146/annurev.immunol.26.021607.090331.
    • (2008) Annu Rev Immunol , vol.26 , pp. 677-704
    • Keir, M.E.1    Butte, M.J.2    Freeman, G.J.3    Sharpe, A.H.4
  • 75
    • 84877896663 scopus 로고    scopus 로고
    • Targeting PD-1/PD-L1 interactions for cancer immunotherapy
    • Zitvogel L, Kroemer G. Targeting PD-1/PD-L1 interactions for cancer immunotherapy. Oncoimmunology (2012) 1:1223-5. doi:10.4161/onci.21335.
    • (2012) Oncoimmunology , vol.1 , pp. 1223-1225
    • Zitvogel, L.1    Kroemer, G.2
  • 76
    • 0036215134 scopus 로고    scopus 로고
    • KIR: diverse, rapidly evolving receptors of innate and adaptive immunity
    • Vilches C, Parham P. KIR: diverse, rapidly evolving receptors of innate and adaptive immunity. Annu Rev Immunol (2002) 20:217-51. doi:10.1146/annurev.immunol.20.092501.134942.
    • (2002) Annu Rev Immunol , vol.20 , pp. 217-251
    • Vilches, C.1    Parham, P.2
  • 77
    • 0037086131 scopus 로고    scopus 로고
    • Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
    • Ruggeri L, Capanni M, Urbani E, Perruccio K, Shlomchik WD, Tosti A, et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science (2002) 295:2097-100. doi:10.1126/science.1068440.
    • (2002) Science , vol.295 , pp. 2097-2100
    • Ruggeri, L.1    Capanni, M.2    Urbani, E.3    Perruccio, K.4    Shlomchik, W.D.5    Tosti, A.6
  • 78
    • 20444394742 scopus 로고    scopus 로고
    • Improved outcome in HLA-identical sibling hematopoietic stem cell transplantation for acute myelogenous leukemia (AML) predicted by KIR and HLA genotypes
    • Hsu KC, Keever-Taylor CA, Wilton A, Pinto C, Heller G, Arkun K, et al. Improved outcome in HLA-identical sibling hematopoietic stem cell transplantation for acute myelogenous leukemia (AML) predicted by KIR and HLA genotypes. Blood (2005) 105:4878-84. doi:10.1182/blood-2004-12-4825.
    • (2005) Blood , vol.105 , pp. 4878-4884
    • Hsu, K.C.1    Keever-Taylor, C.A.2    Wilton, A.3    Pinto, C.4    Heller, G.5    Arkun, K.6
  • 79
    • 0035874543 scopus 로고    scopus 로고
    • Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo
    • Koh CY, Blazar BR, George T, Welniak LA, Capitini CM, Raziuddin A, et al. Augmentation of antitumor effects by NK cell inhibitory receptor blockade in vitro and in vivo. Blood (2001) 97:3132-7. doi:10.1182/blood.V97.10.3132.
    • (2001) Blood , vol.97 , pp. 3132-3137
    • Koh, C.Y.1    Blazar, B.R.2    George, T.3    Welniak, L.A.4    Capitini, C.M.5    Raziuddin, A.6
  • 81
    • 84869856060 scopus 로고    scopus 로고
    • A phase 1 trial of the anti-inhibitory KIR mAb IPH2101 for AML in complete remission
    • Vey N, Bourhis JH, Boissel N, Bordessoule D, Prebet T, Charbonnier A, et al. A phase 1 trial of the anti-inhibitory KIR mAb IPH2101 for AML in complete remission. Blood (2012) 120:4317-23. doi:10.1182/blood-2012-06-437558.
    • (2012) Blood , vol.120 , pp. 4317-4323
    • Vey, N.1    Bourhis, J.H.2    Boissel, N.3    Bordessoule, D.4    Prebet, T.5    Charbonnier, A.6
  • 82
    • 84869819029 scopus 로고    scopus 로고
    • A phase 1 trial of the anti-KIR antibody IPH2101 in patients with relapsed/refractory multiple myeloma
    • Benson DM Jr, Hofmeister CC, Padmanabhan S, Suvannasankha A, Jagannath S, Abonour R, et al. A phase 1 trial of the anti-KIR antibody IPH2101 in patients with relapsed/refractory multiple myeloma. Blood (2012) 120:4324-33. doi:10.1182/blood-2012-06-438028.
    • (2012) Blood , vol.120 , pp. 4324-4333
    • Benson, D.M.1    Hofmeister, C.C.2    Padmanabhan, S.3    Suvannasankha, A.4    Jagannath, S.5    Abonour, R.6
  • 83
    • 84902178747 scopus 로고    scopus 로고
    • KIR/HLA interactions negatively affect rituximab-but not GA101 (obinutuzumab)-induced antibody-dependent cellular cytotoxicity
    • Terszowski G, Klein C, Stern M. KIR/HLA interactions negatively affect rituximab-but not GA101 (obinutuzumab)-induced antibody-dependent cellular cytotoxicity. J Immunol (2014) 192:5618-24. doi:10.4049/jimmunol.1400288.
    • (2014) J Immunol , vol.192 , pp. 5618-5624
    • Terszowski, G.1    Klein, C.2    Stern, M.3
  • 84
    • 84894030202 scopus 로고    scopus 로고
    • Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies
    • Kohrt HE, Thielens A, Marabelle A, Sagiv-Barfi I, Sola C, Chanuc F, et al. Anti-KIR antibody enhancement of anti-lymphoma activity of natural killer cells as monotherapy and in combination with anti-CD20 antibodies. Blood (2014) 123:678-86. doi:10.1182/blood-2013-08-519199.
    • (2014) Blood , vol.123 , pp. 678-686
    • Kohrt, H.E.1    Thielens, A.2    Marabelle, A.3    Sagiv-Barfi, I.4    Sola, C.5    Chanuc, F.6
  • 85
    • 0032546001 scopus 로고    scopus 로고
    • HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C
    • Braud VM, Allan DS, O'Callaghan CA, Söderström K. HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature (1998) 391:795-9. doi:10.1038/35869.
    • (1998) Nature , vol.391 , pp. 795-799
    • Braud, V.M.1    Allan, D.S.2    O'Callaghan, C.A.3    Söderström, K.4
  • 86
    • 0032933419 scopus 로고    scopus 로고
    • Specific recognition of HLA-E, but not classical, HLA class I molecules by soluble CD94/NKG2A and NK cells
    • Brooks AG, Borrego F, Posch PE, Patamawenu A, Scorzelli CJ, Ulbrecht M, et al. Specific recognition of HLA-E, but not classical, HLA class I molecules by soluble CD94/NKG2A and NK cells. J Immunol (1999) 162:305-13.
    • (1999) J Immunol , vol.162 , pp. 305-313
    • Brooks, A.G.1    Borrego, F.2    Posch, P.E.3    Patamawenu, A.4    Scorzelli, C.J.5    Ulbrecht, M.6
  • 87
    • 40249101995 scopus 로고    scopus 로고
    • Human leukocyte antigen-E protein is overexpressed in primary human colorectal cancer
    • Levy EM, Bianchini M, Von Euw EM, Barrio MM, Bravo AI, Furman D, et al. Human leukocyte antigen-E protein is overexpressed in primary human colorectal cancer. Int J Oncol (2008) 32:633-41. doi:10.3892/ijo.32.3.633.
    • (2008) Int J Oncol , vol.32 , pp. 633-641
    • Levy, E.M.1    Bianchini, M.2    Von Euw, E.M.3    Barrio, M.M.4    Bravo, A.I.5    Furman, D.6
  • 88
    • 80053940545 scopus 로고    scopus 로고
    • Expression of the nonclassical HLA-G and HLA-E molecules in laryngeal lesions as biomarkers of tumor invasiveness
    • Silva TG, Crispim JC, Miranda FA, Hassumi MK, de Mello JM, Simões RT, et al. Expression of the nonclassical HLA-G and HLA-E molecules in laryngeal lesions as biomarkers of tumor invasiveness. Histol Histopathol (2011) 26:1487-97. doi:10.1016/j.semcancer.2012.03.003.
    • (2011) Histol Histopathol , vol.26 , pp. 1487-1497
    • Silva, T.G.1    Crispim, J.C.2    Miranda, F.A.3    Hassumi, M.K.4    de Mello, J.M.5    Simões, R.T.6
  • 89
    • 84883712769 scopus 로고    scopus 로고
    • Lung tumor microenvironment induces specific gene expression signature in intratumoral NK cells
    • Gillard-Bocquet M, Caer C, Cagnard N, Crozet L, Perez M, Fridman WH, et al. Lung tumor microenvironment induces specific gene expression signature in intratumoral NK cells. Front Immunol (2013) 4:19. doi:10.3389/fimmu.2013.00019.
    • (2013) Front Immunol , vol.4 , pp. 19
    • Gillard-Bocquet, M.1    Caer, C.2    Cagnard, N.3    Crozet, L.4    Perez, M.5    Fridman, W.H.6
  • 90
    • 80052346280 scopus 로고    scopus 로고
    • Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity
    • Mamessier E, Sylvain A, Thibult ML, Houvenaeghel G, Jacquemier J, Castellano R, et al. Human breast cancer cells enhance self tolerance by promoting evasion from NK cell antitumor immunity. J Clin Invest (2011) 121:3609-22. doi:10.1172/JCI45816.
    • (2011) J Clin Invest , vol.121 , pp. 3609-3622
    • Mamessier, E.1    Sylvain, A.2    Thibult, M.L.3    Houvenaeghel, G.4    Jacquemier, J.5    Castellano, R.6
  • 91
    • 0344247505 scopus 로고
    • cDNA sequences of two inducible T-cell genes
    • Kwon BS, Weissman SM. cDNA sequences of two inducible T-cell genes. Proc Natl Acad Sci U S A (1989) 86:1963-7. doi:10.1073/pnas.86.6.1963.
    • (1989) Proc Natl Acad Sci U S A , vol.86 , pp. 1963-1967
    • Kwon, B.S.1    Weissman, S.M.2
  • 92
    • 0030845586 scopus 로고    scopus 로고
    • 4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses
    • Shuford WW, Klussman K, Tritchler DD, Loo DT, Chalupny J, Siadak AW, et al. 4-1BB costimulatory signals preferentially induce CD8+ T cell proliferation and lead to the amplification in vivo of cytotoxic T cell responses. J Exp Med (1997) 186:47-55. doi:10.1084/jem.186.1.47.
    • (1997) J Exp Med , vol.186 , pp. 47-55
    • Shuford, W.W.1    Klussman, K.2    Tritchler, D.D.3    Loo, D.T.4    Chalupny, J.5    Siadak, A.W.6
  • 93
    • 0031007143 scopus 로고    scopus 로고
    • Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors
    • Melero I, Shuford WW, Newby SA, Aruffo A, Ledbetter JA, Hellström KE, et al. Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors. Nat Med (1997) 3:682-5. doi:10.1038/nm0697-682.
    • (1997) Nat Med , vol.3 , pp. 682-685
    • Melero, I.1    Shuford, W.W.2    Newby, S.A.3    Aruffo, A.4    Ledbetter, J.A.5    Hellström, K.E.6
  • 94
    • 0032535119 scopus 로고    scopus 로고
    • NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies
    • Melero I, Johnston JV, Shufford WW, Mittler RS, Chen L. NK1.1 cells express 4-1BB (CDw137) costimulatory molecule and are required for tumor immunity elicited by anti-4-1BB monoclonal antibodies. Cell Immunol (1998) 190:167-72. doi:10.1006/cimm.1998.1396.
    • (1998) Cell Immunol , vol.190 , pp. 167-172
    • Melero, I.1    Johnston, J.V.2    Shufford, W.W.3    Mittler, R.S.4    Chen, L.5
  • 95
    • 0037108355 scopus 로고    scopus 로고
    • Signaling through NK cell-associated CD137 promotes both helper function for CD8+ cytolytic T cells and responsiveness to IL-2 but not cytolytic activity
    • Wilcox RA, Tamada K, Strome SE, Chen L. Signaling through NK cell-associated CD137 promotes both helper function for CD8+ cytolytic T cells and responsiveness to IL-2 but not cytolytic activity. J Immunol (2002) 169:4230-6. doi:10.4049/jimmunol.169.8.4230.
    • (2002) J Immunol , vol.169 , pp. 4230-4236
    • Wilcox, R.A.1    Tamada, K.2    Strome, S.E.3    Chen, L.4
  • 96
    • 79952124960 scopus 로고    scopus 로고
    • CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies
    • Kohrt HE, Houot R, Goldstein MJ, Weiskopf K, Alizadeh AA, Brody J, et al. CD137 stimulation enhances the antilymphoma activity of anti-CD20 antibodies. Blood (2011) 117:2423-32. doi:10.1182/blood-2010-08-301945.
    • (2011) Blood , vol.117 , pp. 2423-2432
    • Kohrt, H.E.1    Houot, R.2    Goldstein, M.J.3    Weiskopf, K.4    Alizadeh, A.A.5    Brody, J.6
  • 98
    • 84923303086 scopus 로고    scopus 로고
    • A phase 1 study of PF-05082566 (anti-4-1BB) in patients with advanced cancer [abstract]
    • Segal NH, Gopal AK, Bhatia S, Kohrt HE, Levy R, Pishvaian MJ, et al. A phase 1 study of PF-05082566 (anti-4-1BB) in patients with advanced cancer [abstract]. J Clin Oncol (2014) 32:3007. doi:10.1007/s00262-012-1237-1.
    • (2014) J Clin Oncol , vol.32 , pp. 3007
    • Segal, N.H.1    Gopal, A.K.2    Bhatia, S.3    Kohrt, H.E.4    Levy, R.5    Pishvaian, M.J.6
  • 99
    • 77952311199 scopus 로고    scopus 로고
    • Control of immunity by the TNFR-related molecule OX40 (CD134)
    • Croft M. Control of immunity by the TNFR-related molecule OX40 (CD134). Annu Rev Immunol (2010) 28:57-78. doi:10.1146/annurev-immunol-030409-101243.
    • (2010) Annu Rev Immunol , vol.28 , pp. 57-78
    • Croft, M.1
  • 100
    • 40549143697 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells induce NK cell-dependent, tumor antigen-specific T cell cross-priming and tumor regression in mice
    • Liu C, Lou Y, Lizée G, Qin H, Liu S, Rabinovich B, et al. Plasmacytoid dendritic cells induce NK cell-dependent, tumor antigen-specific T cell cross-priming and tumor regression in mice. J Clin Invest (2008) 118:1165-75. doi:10.1172/JCI33583.
    • (2008) J Clin Invest , vol.118 , pp. 1165-1175
    • Liu, C.1    Lou, Y.2    Lizée, G.3    Qin, H.4    Liu, S.5    Rabinovich, B.6
  • 101
    • 0034651736 scopus 로고    scopus 로고
    • Engagement of the OX-40 receptor in vivo enhances antitumor immunity
    • Weinberg AD, Rivera MM, Prell R, Morris A, Ramstad T, Vetto JT, et al. Engagement of the OX-40 receptor in vivo enhances antitumor immunity. J Immunol (2000) 164:2160-9. doi:10.4049/jimmunol.164.4.2160.
    • (2000) J Immunol , vol.164 , pp. 2160-2169
    • Weinberg, A.D.1    Rivera, M.M.2    Prell, R.3    Morris, A.4    Ramstad, T.5    Vetto, J.T.6
  • 102
  • 103
    • 84938305824 scopus 로고    scopus 로고
    • Phase I/II clinical trial of anti-OX40, radiation and cyclophosphamide in patients with prostate cancer: immunological analysis
    • Kovacsovics-Bankowski M, Chisholm L, Vercellini J, Crittenden M, Lary S, et al. Phase I/II clinical trial of anti-OX40, radiation and cyclophosphamide in patients with prostate cancer: immunological analysis. J Immunother Cancer (2013) 1:1-1. doi:10.1186/2051-1426-1-S1-P255.
    • (2013) J Immunother Cancer , vol.1 , pp. 1-1
    • Kovacsovics-Bankowski, M.1    Chisholm, L.2    Vercellini, J.3    Crittenden, M.4    Lary, S.5
  • 104
    • 84895797883 scopus 로고    scopus 로고
    • Subsets of human natural killer cells and their regulatory effects
    • Fu B, Tian Z, Wei H. Subsets of human natural killer cells and their regulatory effects. Immunology (2014) 141:483-9. doi:10.1111/imm.12224.
    • (2014) Immunology , vol.141 , pp. 483-489
    • Fu, B.1    Tian, Z.2    Wei, H.3
  • 105
    • 44849125747 scopus 로고    scopus 로고
    • CD27 defines phenotypically and functionally different human NK cell subsets
    • Vossen MT, Matmati M, Hertoghs KM, Baars PA, Gent MR, Leclercq G, et al. CD27 defines phenotypically and functionally different human NK cell subsets. J Immunol (2008) 180:3739-45. doi:10.4049/jimmunol.180.6.3739.
    • (2008) J Immunol , vol.180 , pp. 3739-3745
    • Vossen, M.T.1    Matmati, M.2    Hertoghs, K.M.3    Baars, P.A.4    Gent, M.R.5    Leclercq, G.6
  • 106
    • 0036143496 scopus 로고    scopus 로고
    • Induction of tumor-specific T cell memory by NK cell-mediated tumor rejection
    • Kelly JM, Darcy PK, Markby JL, Godfrey DI, Takeda K, Yagita H, et al. Induction of tumor-specific T cell memory by NK cell-mediated tumor rejection. Nat Immunol (2002) 3:83-90. doi:10.1038/ni746.
    • (2002) Nat Immunol , vol.3 , pp. 83-90
    • Kelly, J.M.1    Darcy, P.K.2    Markby, J.L.3    Godfrey, D.I.4    Takeda, K.5    Yagita, H.6
  • 107
    • 84863918915 scopus 로고    scopus 로고
    • Development of a human monoclonal antibody for potential therapy of CD27-expressing lymphoma and leukemia
    • Vitale LA, He LZ, Thomas LJ, Widger J, Weidlick J, Crocker A, et al. Development of a human monoclonal antibody for potential therapy of CD27-expressing lymphoma and leukemia. Clin Cancer Res (2012) 18:3812-21. doi:10.1158/1078-0432.CCR-11-3308.
    • (2012) Clin Cancer Res , vol.18 , pp. 3812-3821
    • Vitale, L.A.1    He, L.Z.2    Thomas, L.J.3    Widger, J.4    Weidlick, J.5    Crocker, A.6
  • 108
    • 84885466006 scopus 로고    scopus 로고
    • Agonist anti-human CD27 monoclonal antibody induces T cell activation and tumor immunity in human CD27-transgenic mice
    • He LZ, Prostak N, Thomas LJ, Vitale L, Weidlick J, Crocker A, et al. Agonist anti-human CD27 monoclonal antibody induces T cell activation and tumor immunity in human CD27-transgenic mice. J Immunol (2013) 191:4174-83. doi:10.4049/jimmunol.1300409.
    • (2013) J Immunol , vol.191 , pp. 4174-4183
    • He, L.Z.1    Prostak, N.2    Thomas, L.J.3    Vitale, L.4    Weidlick, J.5    Crocker, A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.