Up-regulation of P2X7 receptor-mediated inhibition of GABA uptake by nerve terminals of the human epileptic neocortex

Epilepsia

Volumn 57, Issue 1, 2016, Pages 99-110

  Barros Barbosa, Aurora R ^a   Fonseca, Ana L ^a   Guerra Gomes, Sõnia ^a   Ferreirinha, Fátima ^a   Santos, Agostinho ^b   Rangel, Rui ^c   Lobo, M Graça ^a   Correia De Sá, Paulo ^a   Cordeiro, J Miguel ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b INSTITUTO NACIONAL DE MEDICINA LEGAL E CIÊNCIAS FORENSES   (Portugal)

^c HOSPITAL DE SANTO ANTÓNIO   (Portugal)

Author keywords

Epilepsy; GABA; Glutamate; High affinity transporters; MTLE; P2X7R

Indexed keywords

4 AMINOBUTYRIC ACID; AMINO ACID RECEPTOR AFFECTING AGENT; ASPARTIC ACID; BENZYLOXYASPARTATE; CARBON; DLG4 PROTEIN, HUMAN; GLIAL FIBRILLARY ACIDIC PROTEIN; MEMBRANE PROTEIN; PURINERGIC P2X7 RECEPTOR; SIGNAL PEPTIDE; SYNAPTOBREVIN 1; SYNAPTOPHYSIN;

ADOLESCENT; ADULT; AGED; CHILD; DRUG EFFECTS; EPILEPSY; FEMALE; HUMAN; MALE; METABOLISM; MIDDLE AGED; NEOCORTEX; PATHOLOGY; PHYSIOLOGY; SYNAPTOSOME; ULTRASTRUCTURE; UPREGULATION; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; ASPARTIC ACID; CARBON ISOTOPES; CHILD; EPILEPSY; EXCITATORY AMINO ACID AGENTS; FEMALE; GAMMA-AMINOBUTYRIC ACID; GLIAL FIBRILLARY ACIDIC PROTEIN; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MEMBRANE PROTEINS; MIDDLE AGED; NEOCORTEX; RECEPTORS, PURINERGIC P2X7; SYNAPTOPHYSIN; SYNAPTOSOMES; UP-REGULATION; VESICLE-ASSOCIATED MEMBRANE PROTEIN 1; YOUNG ADULT;

EID: 84954075485     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/epi.13263     Document Type: Article

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