An essential role for coagulase in staphylococcus aureus biofilm development reveals new therapeutic possibilities for device-related infections

Journal of Infectious Diseases

Volumn 212, Issue 12, 2015, Pages 1883-1893

  Zapotoczna, Marta ^a   McCarthy, Hannah ^c   Rudkin, Justine K ^c   O'Gara, James P ^c   O'Neill, Eoghan ^a,b  

^a BEAUMONT HOSPITAL   (Ireland)

^b Royal College of Surgeons in Ireland   (Ireland)

^c NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Antimicrobial; Biofilm; Coagulase; Infection; Staphylococcus; Susceptibility

Indexed keywords

ANTIBIOTIC AGENT; COAGULASE; FIBRIN; FIBRINOGEN; FIBRINOLYTIC FACTOR; FIBRONECTIN BINDING PROTEIN; N ACETYLGLUCOSAMINE; NATTOKINASE; PLASMIN; POLYSTYRENE; RIFAMPICIN; UNCLASSIFIED DRUG; VANCOMYCIN; ANTIINFECTIVE AGENT; FIBRINOLYTIC AGENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC SENSITIVITY; ARTICLE; AUTOLYSIS; BACTERIAL GROWTH; BACTERIAL STRAIN; BIOFILM; CATHETER INFECTION; CENTRAL VENOUS CATHETER; CONTROLLED STUDY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; JUGULAR VEIN; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; ANIMAL; CATHETER-RELATED INFECTIONS; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADULT; ANIMALS; ANTI-BACTERIAL AGENTS; BIOFILMS; CATHETER-RELATED INFECTIONS; COAGULASE; DISEASE MODELS, ANIMAL; FIBRINOLYTIC AGENTS; HUMANS; RATS, SPRAGUE-DAWLEY; STAPHYLOCOCCUS AUREUS;

EID: 84953915417     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiv319     Document Type: Article

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