Effect of biofilms on recalcitrance of staphylococcal joint infection to antibiotic treatment

Journal of Infectious Diseases

Volumn 211, Issue 4, 2015, Pages 641-650

  Dastghey, Sana ^a,b   Parvizi, Javad ^c   Shapiro, Irving M ^b   Hickok, Noreen J ^b   Otto, Michael ^a  

^a NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

^c ROTHMAN INSTITUTE   (United States)

Author keywords

antibiotic resistance; biofilm; joint infection; MRSA; septic arthritis; Staphylococcus aureus

Indexed keywords

ANTIBIOTIC AGENT; BINDING PROTEIN; CEFAZOLIN; FIBRINOGEN BINDING PROTEIN; FIBRONECTIN BINDING PROTEIN; METICILLIN; PLASMIN; UNCLASSIFIED DRUG; VANCOMYCIN; ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GROWTH; BIOFILM; COLONY FORMING UNIT; CONTROLLED STUDY; CULTURE MEDIUM; INFECTIOUS ARTHRITIS; JOINT ASPIRATION; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS INFECTION; METHICILLIN SUSCEPTIBLE STAPHYLOCOCCUS AUREUS; NONHUMAN; PATHOGENESIS; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; SYNOVIAL FLUID; TRANSPOSON; BACTERIAL COUNT; BIOLOGICAL MODEL; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; HUMAN; MICROBIOLOGY; PHYSIOLOGY; STAPHYLOCOCCUS INFECTION;

ANTI-BACTERIAL AGENTS; ARTHRITIS, INFECTIOUS; BIOFILMS; COLONY COUNT, MICROBIAL; FIBRINOLYSIN; HUMANS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MODELS, BIOLOGICAL; STAPHYLOCOCCAL INFECTIONS; SYNOVIAL FLUID;

EID: 84922441966     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiu514     Document Type: Article

References (38)

1. Zimmerli W, Trampuz A, Ochsner PE. Prosthetic-joint infections. N Engl J Med 2004; 351:1645-54.
2. Shirtliff ME, Mader JT. Acute septic arthritis. Clin Microbiol Rev 2002; 15:527-44.
3. Lora-Tamayo J, Murillo O, Iribarren JA, et al. A large multicenter study of methicillin-susceptible and methicillin-resistant Staphylococcus aureus prosthetic joint infections managed with implant retention. Clin Infect Dis 2013; 56:182-94.
4. Salgado CD, Dash S, Cantey JR, Marculescu CE. Higher risk of failure of methicillin-resistant Staphylococcus aureus prosthetic joint infections. Clin Orthop Relat Res 2007; 461:48-53.
5. D'Agata EM, Webb GF, Horn MA, Moellering RC Jr, Ruan S. Modeling theinvasionofcommunity-acquiredmethicillin-resistant Staphylococcus aureus into hospitals. Clin Infect Dis 2009; 48:274-84.
6. Kourbatova EV, Halvosa JS, King MD, Ray SM, White N, Blumberg HM. Emergence of community-associated methicillin-resistant Staphy-lococcus aureus USA 300 clone as a cause of health care-associated infections among patients with prosthetic joint infections. Am J Infect Control 2005; 33:385-91.
7. Arnold WV, Shirtliff ME, Stoodley P. Bacterial biofilms and peripros-thetic infections. Instr Course Lect 2014; 63:385-91.
8. Stoodley P, Nistico L, Johnson S, et al. Direct demonstration of viable Staphylococcus aureus biofilms in an infected total joint arthroplasty: a case report. J Bone Joint Surg Am 2008; 90:1751-8.
9. Simon GL, Miller HG, Borenstein DG. Synovial fluid inhibits killing of Staphylococcus aureus by neutrophils. Infect Immun 1983; 40:1004-10.
10. Gruber BF, Miller BS, Onnen J, Welling RD, Wojtys EM. Antibacterial properties of synovial fluid in the knee. J Knee Surg 2008; 21:180-5.
11. Swan A, Amer H, Dieppe P. The value of synovial fluid assays in the diagnosis of joint disease: a literature survey. Ann Rheum Dis 2002; 61:493-8.
12. Joo HS, Otto M. Molecular basis of in vivo biofilm formation by bacterial pathogens. Chem Biol 2012; 19:1503-13.
13. Bremell T, Lange S, Yacoub A, Ryden C, Tarkowski A. Experimental Staphylococcus aureus arthritis in mice. Infect Immun 1991; 59: 2615-23.
14. Jefferson KK, Cerca N. Bacterial-bacterial cell interactions in biofilms: detection of polysaccharide intercellular adhesins by blotting and con-focal microscopy. Methods Mol Biol 2006; 341:119-26.
15. Kennedy AD, Otto M, Braughton KR, et al. Epidemic community-associated methicillin-resistant Staphylococcus aureus: recent clonal expansion and diversification. Proc Natl Acad Sci USA 2008; 105:1327-32.
16. DeLeo FR, Otto M, Kreiswirth BN, Chambers HF. Community-associated meticillin-resistant Staphylococcus aureus. Lancet 2010; 375:1557-68.
17. Fey PD, Endres JL, Yajjala VK, et al. A genetic resource for rapid and comprehensive phenotype screening of nonessential Staphylococcus au-reus genes. MBio 2013; 4:e00537-12.
18. Francis KP, Joh D, Bellinger-Kawahara C, Hawkinson MJ, Purchio TF, Contag PR. Monitoring bioluminescent Staphylococcus aureus infections in living mice using a novel luxABCDE construct. Infect Immun 2000; 68:3594-600.
19. Cramton SE, Gerke C, Schnell NF, Nichols WW, Gotz F. The intercellular adhesion (ica) locus is present in Staphylococcus aureus and is required for biofilm formation. Infect Immun 1999; 67:5427-33.
20. Maxe I, Ryden C, Wadstrom T, Rubin K. Specific attachment of Staph-ylococcus aureus to immobilized fibronectin. Infect Immun 1986; 54:695-704.
21. Yonemasu K, Sasaki T, Ohmae R, Kashiba S. Expression of clumping and fibrinogen-binding activities of Staphylococcus aureus at various growth stages. Microbiol Immunol 1991; 35:405-9.
22. Otto M. Staphylococcal biofilms. Curr Top Microbiol Immunol 2008; 322:207-28.
23. Kaplan JB, Velliyagounder K, Ragunath C, et al. Genes involved in the synthesis and degradation of matrix polysaccharide in Actinobacillus actinomycetemcomitans and Actinobacillus pleuropneumoniae biofilms. J Bacteriol 2004; 186:8213-20.
24. Jonsson IM, Arvidson S, Foster S, Tarkowski A. Sigma factor B and RsbU are required for virulence in Staphylococcus aureus-induced arthritis and sepsis. Infect Immun 2004; 72:6106-11.
25. Josefsson E, Hartford O, O'Brien L, Patti JM, Foster T. Protection against experimental Staphylococcus aureus arthritis by vaccination with clumping factor A, a novel virulence determinant. J Infect Dis 2001; 184:1572-80.
26. Palmqvist N, Foster T, Fitzgerald JR, Josefsson E, Tarkowski A. Fibro-nectin-binding proteins and fibrinogen-binding clumping factors play distinct roles in staphylococcal arthritis and systemic inflammation. J Infect Dis 2005; 191:791-8.
27. Horsburgh MJ, Aish JL, White IJ, Shaw L, Lithgow JK, Foster SJ. sigmaB modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4. J Bacteriol 2002; 184:5457-67.
28. Zeller V, Durand F, Kitzis MD, et al. Continuous cefazolin infusion to treat bone and joint infections: clinical efficacy, feasibility, safety, and serum and bone concentrations. Antimicrob Agents Chemother 2009; 53:883-7.
29. Marschall J, Lane MA, Beekmann SE, Polgreen PM, Babcock HM. Current management of prosthetic joint infections in adults: results of an Emerging Infections Network survey. Int J Antimicrob Agents 2013; 41:272-7.
30. Dellinger EP, Gross PA, Barrett TL, et al. Quality standard for antimicrobial prophylaxis in surgical procedures. The Infectious Diseases Society of America. Infect Control Hosp Epidemiol 1994; 15:182-8.
31. Yamada K, Matsumoto K, Tokimura F, Okazaki H, Tanaka S. Are bone and serum cefazolin concentrations adequate for antimicrobial prophylaxis? Clin Orthop Relat Res 2011; 469:3486-94.
32. Banerjee R, Fernandez MG, Enthaler N, Graml C, Greenwood-Quaintance KE, Patel R. Combinations of cefoxitin plus other beta-lactams are synergistic in vitro against community associated methicil-lin-resistant Staphylococcus aureus. Eur J Clin Microbiol Infect Dis 2013; 32:827-33.
33. Barrett AJ. The possible role of neutrophil proteinases in damage to articular cartilage. Agents Actions 1978; 8:11-8.
34. Lack CH. Chondrolysis in arthritis. J Bone Joint Surg Br 1959; 41-B:384-7.
35. Lijnen HR. Pleiotropic functions of plasminogen activator inhibitor-1. J Thromb Haemost 2005; 3:35-45.
36. Lack CH, Rogers HJ. Action of plasmin on cartilage. Nature 1958; 182:948-9.
37. Hsieh YS, Yang SF, Lue KH, Lu KH. Clinical correlation with the PA/plasmin system in septic arthritis of the knee. Clin Orthop Relat Res 2006; 447:172-8.
38. Guo Y, Li J, Hagstrom E, Ny T. Protective effects of plasmin(ogen) in a mouse model of Staphylococcus aureus-induced arthritis. Arthritis Rheum 2008; 58:764-72.