메뉴 건너뛰기




Volumn 8, Issue 12, 2013, Pages

Staphylococcus aureus sarA regulates inflammation and colonization during central nervous system biofilm formation

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; BACTERIAL PROTEINS; BACTERIAL TOXINS; BIOFILMS; BRAIN; CATHETER-RELATED INFECTIONS; CEREBRAL VENTRICLES; CHILD; HUMANS; INFLAMMATION; MALE; MICE; MUTATION; PEPTIDE HYDROLASES; POSTOPERATIVE COMPLICATIONS; STAPHYLOCOCCUS AUREUS; TRANS-ACTIVATORS;

EID: 84893532039     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0084089     Document Type: Article
Times cited : (27)

References (41)
  • 1
    • 84872525674 scopus 로고    scopus 로고
    • Incidence and risk factors of ventriculoperitoneal shunt infections in children: A study of 333 consecutive shunts in 6 years
    • Lee JK, Seok JY, Lee JH, Choi EH, Phi JH, et al. (2012) Incidence and risk factors of ventriculoperitoneal shunt infections in children: A study of 333 consecutive shunts in 6 years. J Korean Med Sci 27: 1563-1568.
    • (2012) J Korean Med Sci , vol.27 , pp. 1563-1568
    • Lee, J.K.1    Seok, J.Y.2    Lee, J.H.3    Choi, E.H.4    Phi, J.H.5
  • 5
    • 84867603967 scopus 로고    scopus 로고
    • Biofilm-infected intracerebroventricular shunts elicit inflammation within the central nervous system
    • Snowden JN, Beaver M, Smeltzer MS, Kielian T (2012) Biofilm-infected intracerebroventricular shunts elicit inflammation within the central nervous system. Infect Immun 80: 3206-3214.
    • (2012) Infect Immun , vol.80 , pp. 3206-3214
    • Snowden, J.N.1    Beaver, M.2    Smeltzer, M.S.3    Kielian, T.4
  • 6
    • 79953309287 scopus 로고    scopus 로고
    • Murine immune response to a chronic staphylococcus aureus biofilm infection
    • Prabhakara R, Harro JM, Leid JG, Harris M, Shirtliff ME (2011) Murine immune response to a chronic staphylococcus aureus biofilm infection. Infect Immun 79: 1789-1796.
    • (2011) Infect Immun , vol.79 , pp. 1789-1796
    • Prabhakara, R.1    Harro, J.M.2    Leid, J.G.3    Harris, M.4    Shirtliff, M.E.5
  • 7
    • 79958071653 scopus 로고    scopus 로고
    • Staphylococcus aureus biofilms prevent macrophage phagocytosis and attenuate inflammation in vivo
    • Thurlow LR, Hanke ML, Fritz T, Angle A, Aldrich A, et al. (2011) Staphylococcus aureus biofilms prevent macrophage phagocytosis and attenuate inflammation in vivo. J Immunol 186: 6585-6596.
    • (2011) J Immunol , vol.186 , pp. 6585-6596
    • Thurlow, L.R.1    Hanke, M.L.2    Fritz, T.3    Angle, A.4    Aldrich, A.5
  • 8
    • 84864541186 scopus 로고    scopus 로고
    • MyD88-dependent signaling influences fibrosis and alternative macrophage activation during staphylococcus aureus biofilm infection
    • Hanke ML, Angle A, Kielian T (2012) MyD88-dependent signaling influences fibrosis and alternative macrophage activation during staphylococcus aureus biofilm infection. PLoS One 7: e42476.
    • (2012) PLoS One , vol.7
    • Hanke, M.L.1    Angle, A.2    Kielian, T.3
  • 9
    • 84874286623 scopus 로고    scopus 로고
    • Targeting macrophage activation for the prevention and treatment of staphylococcus aureus biofilm infections
    • Hanke ML, Heim CE, Angle A, Sanderson SD, Kielian T (2013) Targeting macrophage activation for the prevention and treatment of staphylococcus aureus biofilm infections. J Immunol 190: 2159-2168.
    • (2013) J Immunol , vol.190 , pp. 2159-2168
    • Hanke, M.L.1    Heim, C.E.2    Angle, A.3    Sanderson, S.D.4    Kielian, T.5
  • 12
    • 54449099604 scopus 로고    scopus 로고
    • Factors contributing to the biofilm-deficient phenotype of staphylococcus aureus sarA mutants
    • Tsang LH, Cassat JE, Shaw LN, Beenken KE, Smeltzer MS (2008) Factors contributing to the biofilm-deficient phenotype of staphylococcus aureus sarA mutants. PLoS One 3: e3361.
    • (2008) PLoS One , vol.3
    • Tsang, L.H.1    Cassat, J.E.2    Shaw, L.N.3    Beenken, K.E.4    Smeltzer, M.S.5
  • 13
    • 84870236227 scopus 로고    scopus 로고
    • sarA-mediated repression of protease production plays a key role in the pathogenesis of staphylococcus aureus USA300 isolates
    • Zielinska AK, Beenken KE, Mrak LN, Spencer HJ, Post GR, et al. (2012) sarA-mediated repression of protease production plays a key role in the pathogenesis of staphylococcus aureus USA300 isolates. Mol Microbiol 86: 1183-1196.
    • (2012) Mol Microbiol , vol.86 , pp. 1183-1196
    • Zielinska, A.K.1    Beenken, K.E.2    Mrak, L.N.3    Spencer, H.J.4    Post, G.R.5
  • 14
    • 67449128169 scopus 로고    scopus 로고
    • TLR2 deficiency leads to increased Th17 infiltrates in experimental brain abscesses
    • Nichols JR, Aldrich AL, Mariani MM, Vidlak D, Esen N, et al. (2009) TLR2 deficiency leads to increased Th17 infiltrates in experimental brain abscesses. J Immunol 182: 7119-7130.
    • (2009) J Immunol , vol.182 , pp. 7119-7130
    • Nichols, J.R.1    Aldrich, A.L.2    Mariani, M.M.3    Vidlak, D.4    Esen, N.5
  • 16
    • 38749147716 scopus 로고    scopus 로고
    • Both TLR2 and TLR4 are required for the effective immune response in Staphylococcus aureus-induced experimental murine brain abscess
    • DOI 10.2353/ajpath.2008.070567
    • Stenzel W, Soltek S, Sanchez-Ruiz M, Akira S, Miletic H, et al. (2008) Both TLR2 and TLR4 are required for the effective immune response in staphylococcus aureus-induced experimental murine brain abscess. Am J Pathol 172: 132-145. (Pubitemid 351186375)
    • (2008) American Journal of Pathology , vol.172 , Issue.1 , pp. 132-145
    • Stenzel, W.1    Soltek, S.2    Sanchez-Ruiz, M.3    Akira, S.4    Miletic, H.5    Schluter, D.6    Deckert, M.7
  • 17
    • 0036156087 scopus 로고    scopus 로고
    • Strain-dependent differences in the regulatory roles of sarA and agr in Staphylococcus aureus
    • DOI 10.1128/IAI.70.2.470-480.2002
    • Blevins JS, Beenken KE, Elasri MO, Hurlburt BK, Smeltzer MS (2002) Strain-dependent differences in the regulatory roles of sarA and agr in staphylococcus aureus. Infect Immun 70: 470-480. (Pubitemid 34083803)
    • (2002) Infection and Immunity , vol.70 , Issue.2 , pp. 470-480
    • Blevins, J.S.1    Beenken, K.E.2    Elasri, M.O.3    Hurlburt, B.K.4    Smeltzer, M.S.5
  • 18
    • 33749642880 scopus 로고    scopus 로고
    • Transcriptional profiling of a Staphylococcus aureus clinical isolate and its isogenic agr and sarA mutants reveals global differences in comparison to the laboratory strain RN6390
    • DOI 10.1099/mic.0.29033-0
    • Cassat J, Dunman PM, Murphy E, Projan SJ, Beenken KE, et al. (2006) Transcriptional profiling of a staphylococcus aureus clinical isolate and its isogenic agr and sarA mutants reveals global differences in comparison to the laboratory strain RN6390. Microbiology 152: 3075-3090. (Pubitemid 44542387)
    • (2006) Microbiology , vol.152 , Issue.10 , pp. 3075-3090
    • Cassat, J.1    Dunman, P.M.2    Murphy, E.3    Projan, S.J.4    Beenken, K.E.5    Palm, K.J.6    Yang, S.-J.7    Rice, K.C.8    Bayles, K.W.9    Smeltzer, M.S.10
  • 19
    • 0037634030 scopus 로고    scopus 로고
    • Mutation of sarA in Staphylococcus aureus limits biofilm formation
    • DOI 10.1128/IAI.71.7.4206-4211.2003
    • Beenken KE, Blevins JS, Smeltzer MS (2003) Mutation of sarA in staphylococcus aureus limits biofilm formation. Infect Immun 71: 4206-4211. (Pubitemid 36753758)
    • (2003) Infection and Immunity , vol.71 , Issue.7 , pp. 4206-4211
    • Beenken, K.E.1    Blevins, J.S.2    Smeltzer, M.S.3
  • 20
    • 58849122822 scopus 로고    scopus 로고
    • Role of mgrA and sarA in methicillin-resistant staphylococcus aureus autolysis and resistance to cell wall-active antibiotics
    • Trotonda MP, Xiong YQ, Memmi G, Bayer AS, Cheung AL (2009) Role of mgrA and sarA in methicillin-resistant staphylococcus aureus autolysis and resistance to cell wall-active antibiotics. J Infect Dis 199: 209-218.
    • (2009) J Infect Dis , vol.199 , pp. 209-218
    • Trotonda, M.P.1    Xiong, Y.Q.2    Memmi, G.3    Bayer, A.S.4    Cheung, A.L.5
  • 21
    • 33750294761 scopus 로고    scopus 로고
    • Regulation of Staphylococcus aureus alpha-toxin gene (hla) expression by agr, sarA, and sae in vitro and in experimental infective endocarditis
    • DOI 10.1086/508210
    • Xiong YQ, Willard J, Yeaman MR, Cheung AL, Bayer AS (2006) Regulation of staphylococcus aureus alpha-toxin gene (hla) expression by agr, sarA, and sae in vitro and in experimental infective endocarditis. J Infect Dis 194: 1267-1275. (Pubitemid 44630972)
    • (2006) Journal of Infectious Diseases , vol.194 , Issue.9 , pp. 1267-1275
    • Xiong, Y.Q.1    Willard, J.2    Yeaman, M.R.3    Cheung, A.L.4    Bayer, A.S.5
  • 22
    • 79958041272 scopus 로고    scopus 로고
    • Defining the strain-dependent impact of the staphylococcal accessory regulator (sarA) on the alpha-toxin phenotype of staphylococcus aureus
    • Zielinska AK, Beenken KE, Joo HS, Mrak LN, Griffin LM, et al. (2011) Defining the strain-dependent impact of the staphylococcal accessory regulator (sarA) on the alpha-toxin phenotype of staphylococcus aureus. J Bacteriol 193: 2948-2958.
    • (2011) J Bacteriol , vol.193 , pp. 2948-2958
    • Zielinska, A.K.1    Beenken, K.E.2    Joo, H.S.3    Mrak, L.N.4    Griffin, L.M.5
  • 23
    • 0034783704 scopus 로고    scopus 로고
    • Diminished virulence of an alpha-toxin mutant of Staphylococcus aureus in experimental brain abscesses
    • DOI 10.1128/IAI.69.11.6902-6911.2001
    • Kielian T, Cheung A, Hickey WF (2001) Diminished virulence of an alpha-toxin mutant of staphylococcus aureus in experimental brain abscesses. Infect Immun 69: 6902-6911. (Pubitemid 32995450)
    • (2001) Infection and Immunity , vol.69 , Issue.11 , pp. 6902-6911
    • Kielian, T.1    Cheung, A.2    Hickey, W.F.3
  • 24
    • 80054795572 scopus 로고    scopus 로고
    • Inflammasome activation and IL-1beta/IL-18 processing are influenced by distinct pathways in microglia
    • Hanamsagar R, Torres V, Kielian T (2011) Inflammasome activation and IL-1beta/IL-18 processing are influenced by distinct pathways in microglia. J Neurochem 119: 736-748.
    • (2011) J Neurochem , vol.119 , pp. 736-748
    • Hanamsagar, R.1    Torres, V.2    Kielian, T.3
  • 25
    • 84862001068 scopus 로고    scopus 로고
    • saeRS and sarA act synergistically to repress protease production and promote biofilm formation in staphylococcus aureus
    • Mrak LN, Zielinska AK, Beenken KE, Mrak IN, Atwood DN, et al. (2012) saeRS and sarA act synergistically to repress protease production and promote biofilm formation in staphylococcus aureus. PLoS One 7: e38453.
    • (2012) PLoS One , vol.7
    • Mrak, L.N.1    Zielinska, A.K.2    Beenken, K.E.3    Mrak, I.N.4    Atwood, D.N.5
  • 26
    • 85047687230 scopus 로고    scopus 로고
    • Receptor-dependent and -independent immunomodulatory effects of phenol-soluble modulin peptides from staphylococcus aureus on human neutrophils are abrogated through peptide inactivation by reactive oxygen species
    • Forsman H, Christenson K, Bylund J, Dahlgren C (2012) Receptor-dependent and -independent immunomodulatory effects of phenol-soluble modulin peptides from staphylococcus aureus on human neutrophils are abrogated through peptide inactivation by reactive oxygen species. Infect Immun 80: 1987-1995.
    • (2012) Infect Immun , vol.80 , pp. 1987-1995
    • Forsman, H.1    Christenson, K.2    Bylund, J.3    Dahlgren, C.4
  • 27
    • 77957971178 scopus 로고    scopus 로고
    • Basis of virulence in community-associated methicillin-resistant staphylococcus aureus
    • Otto M (2010) Basis of virulence in community-associated methicillin-resistant staphylococcus aureus. Annu Rev Microbiol 64: 143-162.
    • (2010) Annu Rev Microbiol , vol.64 , pp. 143-162
    • Otto, M.1
  • 28
    • 48149085307 scopus 로고    scopus 로고
    • Relative quantitative comparisons of the extracellular protein profiles of staphylococcus aureus UAMS-1 and its sarA, agr, and sarA agr regulatory mutants using one-dimensional polyacrylamide gel electrophoresis and nanocapillary liquid chromatography coupled with tandem mass spectrometry
    • Jones RC, Deck J, Edmondson RD, Hart ME (2008) Relative quantitative comparisons of the extracellular protein profiles of staphylococcus aureus UAMS-1 and its sarA, agr, and sarA agr regulatory mutants using one-dimensional polyacrylamide gel electrophoresis and nanocapillary liquid chromatography coupled with tandem mass spectrometry. J Bacteriol 190: 5265-5278.
    • (2008) J Bacteriol , vol.190 , pp. 5265-5278
    • Jones, R.C.1    Deck, J.2    Edmondson, R.D.3    Hart, M.E.4
  • 29
    • 0037383975 scopus 로고    scopus 로고
    • Risk factors for pediatric ventriculoperitoneal shunt infection and predictors of infectious pathogens
    • DOI 10.1086/368191
    • McGirt MJ, Zaas A, Fuchs HE, George TM, Kaye K, et al. (2003) Risk factors for pediatric ventriculoperitoneal shunt infection and predictors of infectious pathogens. Clin Infect Dis 36: 858-862. (Pubitemid 36403518)
    • (2003) Clinical Infectious Diseases , vol.36 , Issue.7 , pp. 858-862
    • McGirt, M.J.1    Zaas, A.2    Fuchs, H.E.3    George, T.M.4    Kaye, K.5    Sexton, D.J.6
  • 30
    • 0035313548 scopus 로고    scopus 로고
    • CXC chemokine receptor-2 ligands are required for neutrophil-mediated host defense in experimental brain abscesses
    • Kielian T, Barry B, Hickey WF (2001) CXC chemokine receptor-2 ligands are required for neutrophil-mediated host defense in experimental brain abscesses. J Immunol 166: 4634-4643. (Pubitemid 32233750)
    • (2001) Journal of Immunology , vol.166 , Issue.7 , pp. 4634-4643
    • Kielian, T.1    Barry, B.2    Hickey, W.F.3
  • 31
    • 84884278572 scopus 로고    scopus 로고
    • Staphopains modulate staphylococcus aureus biofilm integrity
    • Mootz JM, Malone CL, Shaw LN, Horswill AR (2013) Staphopains modulate staphylococcus aureus biofilm integrity. Infect Immun 81: 3227-3238.
    • (2013) Infect Immun , vol.81 , pp. 3227-3238
    • Mootz, J.M.1    Malone, C.L.2    Shaw, L.N.3    Horswill, A.R.4
  • 32
    • 80051548705 scopus 로고    scopus 로고
    • Protective role of IL-1beta against post-arthroplasty staphylococcus aureus infection
    • Bernthal NM, Pribaz JR, Stavrakis AI, Billi F, Cho JS, et al. (2011) Protective role of IL-1beta against post-arthroplasty staphylococcus aureus infection. J Orthop Res 29: 1621-1626.
    • (2011) J Orthop Res , vol.29 , pp. 1621-1626
    • Bernthal, N.M.1    Pribaz, J.R.2    Stavrakis, A.I.3    Billi, F.4    Cho, J.S.5
  • 33
    • 79959385362 scopus 로고    scopus 로고
    • Staphylococcus epidermidis uses distinct mechanisms of biofilm formation to interfere with phagocytosis and activation of mouse macrophage-like cells 774A.1
    • Schommer NN, Christner M, Hentschke M, Ruckdeschel K, Aepfelbacher M, et al. (2011) Staphylococcus epidermidis uses distinct mechanisms of biofilm formation to interfere with phagocytosis and activation of mouse macrophage-like cells 774A.1. Infect Immun 79: 2267-2276.
    • (2011) Infect Immun , vol.79 , pp. 2267-2276
    • Schommer, N.N.1    Christner, M.2    Hentschke, M.3    Ruckdeschel, K.4    Aepfelbacher, M.5
  • 34
    • 77953236848 scopus 로고    scopus 로고
    • Current concepts in biofilm formation of staphylococcus epidermidis
    • Fey PD, Olson ME (2010) Current concepts in biofilm formation of staphylococcus epidermidis. Future Microbiol 5: 917-933.
    • (2010) Future Microbiol , vol.5 , pp. 917-933
    • Fey, P.D.1    Olson, M.E.2
  • 36
    • 84859852812 scopus 로고    scopus 로고
    • Molecular basis of staphylococcus epidermidis infections
    • Otto M (2012) Molecular basis of staphylococcus epidermidis infections. Semin Immunopathol 34: 201-214.
    • (2012) Semin Immunopathol , vol.34 , pp. 201-214
    • Otto, M.1
  • 37
    • 0033035830 scopus 로고    scopus 로고
    • The staphylococcal accessory regulator (sar) represses transcription of the Staphylococcus aureus collagen adhesin gene (cna) in an agr-independent manner
    • DOI 10.1046/j.1365-2958.1999.01475.x
    • Blevins JS, Gillaspy AF, Rechtin TM, Hurlburt BK, Smeltzer MS (1999) The staphylococcal accessory regulator (sar) represses transcription of the staphylococcus aureus collagen adhesin gene (cna) in an agr-independent manner. Mol Microbiol 33: 317-326. (Pubitemid 29322518)
    • (1999) Molecular Microbiology , vol.33 , Issue.2 , pp. 317-326
    • Blevins, J.S.1    Gillaspy, A.F.2    Rechtin, T.M.3    Hurlburt, B.K.4    Smeltzer, M.S.5
  • 38
    • 80053595961 scopus 로고    scopus 로고
    • Proteolytic cleavage inactivates the staphylococcus aureus lipoteichoic acid synthase
    • Wormann ME, Reichmann NT, Malone CL, Horswill AR, Grundling A (2011) Proteolytic cleavage inactivates the staphylococcus aureus lipoteichoic acid synthase. J Bacteriol 193: 5279-5291.
    • (2011) J Bacteriol , vol.193 , pp. 5279-5291
    • Wormann, M.E.1    Reichmann, N.T.2    Malone, C.L.3    Horswill, A.R.4    Grundling, A.5
  • 39
    • 34548499578 scopus 로고    scopus 로고
    • Staphylococcus aureus biofilm metabolism and the influence of arginine on polysaccharide intercellular adhesin synthesis, biofilm formation, and pathogenesis
    • DOI 10.1128/IAI.00509-07
    • Zhu Y, Weiss EC, Otto M, Fey PD, Smeltzer MS, et al. (2007) Staphylococcus aureus biofilm metabolism and the influence of arginine on polysaccharide intercellular adhesin synthesis, biofilm formation, and pathogenesis. Infect Immun 75: 4219-4226. (Pubitemid 47378077)
    • (2007) Infection and Immunity , vol.75 , Issue.9 , pp. 4219-4226
    • Zhu, Y.1    Weiss, E.C.2    Otto, M.3    Fey, P.D.4    Smeltzer, M.S.5    Somerville, G.A.6
  • 40
    • 36549081269 scopus 로고    scopus 로고
    • Investigation of biofilm formation in clinical isolates of Staphylococcus aureus
    • DOI 10.1385/1-59745-468-0:127, Methicillin-Resistant Staphylococcus aureus (MRSA) Protocols
    • Cassat JE, Lee CY, Smeltzer MS (2007) Investigation of biofilm formation in clinical isolates of staphylococcus aureus. Methods Mol Biol 391: 127-144. (Pubitemid 350190021)
    • (2007) Methods in Molecular Biology , vol.391 , pp. 127-144
    • Cassat, J.E.1    Lee, C.Y.2    Smeltzer, M.S.3
  • 41
    • 27744583563 scopus 로고    scopus 로고
    • Toll-like receptor 2 modulates the proinflammatory milieu in Staphylococcus aureus-induced brain abscess
    • DOI 10.1128/IAI.73.11.7428-7435.2005
    • Kielian T, Haney A, Mayes PM, Garg S, Esen N (2005) Toll-like receptor 2 modulates the proinflammatory milieu in staphylococcus aureus-induced brain abscess. Infect Immun 73: 7428-7435. (Pubitemid 41587646) Stroke
    • (2005) Infection and Immunity , vol.73 , Issue.11 , pp. 7428-7435
    • Kielian, T.1    Haney, A.2    Mayes, P.M.3    Garg, S.4    Esen, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.