Blockade of IL-18 signaling diminished neuropathic pain and enhanced the efficacy of morphine and buprenorphine

Molecular and Cellular Neuroscience

Volumn 71, Issue , 2016, Pages 114-124

  Pilat, Dominika ^a   Piotrowska, Anna ^a   Rojewska, Ewelina ^a   Jurga, Agnieszka ^a   Ślusarczyk, Joanna ^a   Makuch, Wioletta ^a   Basta Kaim, Agnieszka ^a   Przewlocka, Barbara ^a   Mika, Joanna ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

IL 18; IL 18BP; IL 18R; Neuropathic pain; Opioid treatment

Indexed keywords

BUPRENORPHINE; DECTIN 1; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 18; INTERLEUKIN 18 BINDING PROTEIN; INTERLEUKIN 18 RECEPTOR; MESSENGER RNA; MORPHINE; INTERLEUKIN-18 BINDING PROTEIN; NARCOTIC ANALGESIC AGENT; SIGNAL PEPTIDE;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; ASTROCYTE; CHRONIC CONSTRICTION INJURY; COLD PLATE TEST; CONTROLLED STUDY; DRUG EFFICACY; GENE EXPRESSION; HYPERALGESIA; LUMBAR SPINAL CORD; MALE; MICROGLIA; NEUROPATHIC PAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SCIATIC NERVE; TAIL FLICK TEST; VON FREY TEST; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; DRUG POTENTIATION; GENETICS; METABOLISM; NERVE CELL; NEURALGIA; SPINAL CORD; WISTAR RAT;

ANALGESICS, OPIOID; ANIMALS; ASTROCYTES; BUPRENORPHINE; CELLS, CULTURED; DRUG SYNERGISM; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTERLEUKIN-18; MALE; MORPHINE; NEURALGIA; NEURONS; RATS; RATS, WISTAR; RECEPTORS, INTERLEUKIN-18; SPINAL CORD;

EID: 84953708268     PISSN: 10447431     EISSN: 10959327     Source Type: Journal    
DOI: 10.1016/j.mcn.2015.12.013     Document Type: Article

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