메뉴 건너뛰기




Volumn 47, Issue , 2016, Pages S52-S61

Effects of macroporous, strontium loaded xerogel-scaffolds on new bone formation in critical-size metaphyseal fracture defects in ovariectomized rats

Author keywords

biomaterial; fracture defect; metaphysis; osteoporosis; scaffold; strontium

Indexed keywords

ALKALINE PHOSPHATASE; BIOMATERIAL; BONE MORPHOGENETIC PROTEIN 2; COLLAGEN; OSTEOCALCIN; OSTEOCLAST DIFFERENTIATION FACTOR; OSTEOPROTEGERIN; SILICON DIOXIDE; STRONTIUM; TRANSCRIPTION FACTOR RUNX2; BMPR2 PROTEIN, RAT; BONE CEMENT; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; CALCIUM PHOSPHATE;

EID: 84953432041     PISSN: 00201383     EISSN: 18790267     Source Type: Journal    
DOI: 10.1016/S0020-1383(16)30013-4     Document Type: Article
Times cited : (21)

References (44)
  • 1
    • 84877714222 scopus 로고    scopus 로고
    • A new metaphyseal bone defect model in osteoporotic rats to study biomaterials for the enhancement of bone healing in osteoporotic fractures
    • V Alt, U Thormann, S Ray, D Zahner, L Durselen, K Lips et al. A new metaphyseal bone defect model in osteoporotic rats to study biomaterials for the enhancement of bone healing in osteoporotic fractures Acta Biomater 9 2013 7035 7042
    • (2013) Acta Biomater , vol.9 , pp. 7035-7042
    • Alt, V.1    Thormann, U.2    Ray, S.3    Zahner, D.4    Durselen, L.5    Lips, K.6
  • 2
    • 84882909140 scopus 로고    scopus 로고
    • Bone formation induced by strontium modified calcium phosphate cement in critical-size metaphyseal fracture defects in ovariectomized rats
    • U Thormann, S Ray, U Sommer, T Elkhassawna, T Rehling, M Hundgeburth et al. Bone formation induced by strontium modified calcium phosphate cement in critical-size metaphyseal fracture defects in ovariectomized rats Biomaterials 34 2013 8589 8598
    • (2013) Biomaterials , vol.34 , pp. 8589-8598
    • Thormann, U.1    Ray, S.2    Sommer, U.3    Elkhassawna, T.4    Rehling, T.5    Hundgeburth, M.6
  • 3
    • 84885332091 scopus 로고    scopus 로고
    • Bio-inspired silica-collagen materials: Applications and perspectives in the medical field
    • S Heinemann, T Coradin, MF Desimone Bio-inspired silica-collagen materials: applications and perspectives in the medical field Biomater Sci 1 2013 688 702
    • (2013) Biomater Sci , vol.1 , pp. 688-702
    • Heinemann, S.1    Coradin, T.2    Desimone, M.F.3
  • 5
    • 84855875848 scopus 로고    scopus 로고
    • Effect of silica and hydroxyapatite mineralization on the mechanical properties and the biocompatibility of nanocomposite collagen scaffolds
    • S Heinemann, C Heinemann, M Jager, J Neunzehn, HP Wiesmann, T Hanke Effect of silica and hydroxyapatite mineralization on the mechanical properties and the biocompatibility of nanocomposite collagen scaffolds ACS Appl Mater Interfaces 3 2011 4323 4331
    • (2011) ACS Appl Mater Interfaces , vol.3 , pp. 4323-4331
    • Heinemann, S.1    Heinemann, C.2    Jager, M.3    Neunzehn, J.4    Wiesmann, H.P.5    Hanke, T.6
  • 6
    • 80054987970 scopus 로고    scopus 로고
    • Possibilities and limitations of preparing silica/collagen/hydroxyapatite composite xerogels as load-bearing biomaterials
    • S Heinemann, T Coradin, H Worch, HP Wiesmann, T Hanke Possibilities and limitations of preparing silica/collagen/hydroxyapatite composite xerogels as load-bearing biomaterials Compos Sci Technol 71 2011 1873 1880
    • (2011) Compos Sci Technol , vol.71 , pp. 1873-1880
    • Heinemann, S.1    Coradin, T.2    Worch, H.3    Wiesmann, H.P.4    Hanke, T.5
  • 7
    • 34147177628 scopus 로고    scopus 로고
    • Strontium ranelate: New insights into its dual mode of action
    • PJ Marie Strontium ranelate: New insights into its dual mode of action Bone 40 2007 S5 S8
    • (2007) Bone , vol.40 , pp. S5-S8
    • Marie, P.J.1
  • 8
    • 81355127486 scopus 로고    scopus 로고
    • The cross-talk between osteoclasts and osteoblasts in response to strontium treatment: Involvement of osteoprotegerin
    • S Peng, XS Liu, S Huang, Z Li, H Pan, W Zhen et al. The cross-talk between osteoclasts and osteoblasts in response to strontium treatment: involvement of osteoprotegerin Bone 49 2011 1290 1298
    • (2011) Bone , vol.49 , pp. 1290-1298
    • Peng, S.1    Liu, X.S.2    Huang, S.3    Li, Z.4    Pan, H.5    Zhen, W.6
  • 10
    • 84865281791 scopus 로고    scopus 로고
    • Effects of strontium ranelate on osseointegration of titanium implant in osteoporotic rats
    • Y Li, X Li, G Song, K Chen, G Yin, J Hu Effects of strontium ranelate on osseointegration of titanium implant in osteoporotic rats Clin Oral Implants Res 23 2012 1038 1044
    • (2012) Clin Oral Implants Res , vol.23 , pp. 1038-1044
    • Li, Y.1    Li, X.2    Song, G.3    Chen, K.4    Yin, G.5    Hu, J.6
  • 12
    • 84863473357 scopus 로고    scopus 로고
    • Fluorescence microscopic analysis of bone osseointegration of strontium-substituted hydroxyapatite implants
    • DL Fu, QH Jiang, FM He, GL Yang, L Liu Fluorescence microscopic analysis of bone osseointegration of strontium-substituted hydroxyapatite implants J Zhejiang Univ Sci B 13 2012 364 371
    • (2012) J Zhejiang Univ Sci B , vol.13 , pp. 364-371
    • Fu, D.L.1    Jiang, Q.H.2    He, F.M.3    Yang, G.L.4    Liu, L.5
  • 13
    • 77954535782 scopus 로고    scopus 로고
    • A novel method for local administration of strontium from implant surfaces
    • J Forsgren, H Engqvist A novel method for local administration of strontium from implant surfaces J Mater Sci Mater Med 21 2010 1605 1609
    • (2010) J Mater Sci Mater Med , vol.21 , pp. 1605-1609
    • Forsgren, J.1    Engqvist, H.2
  • 14
    • 84878111750 scopus 로고    scopus 로고
    • Accelerated bone ingrowth by local delivery of strontium from surface functionalized titanium implants
    • OZ Andersen, V Offermanns, M Sillassen, KP Almtoft, IH Andersen, S Sorensen et al. Accelerated bone ingrowth by local delivery of strontium from surface functionalized titanium implants Biomaterials 34 2013 5883 5890
    • (2013) Biomaterials , vol.34 , pp. 5883-5890
    • Andersen, O.Z.1    Offermanns, V.2    Sillassen, M.3    Almtoft, K.P.4    Andersen, I.H.5    Sorensen, S.6
  • 15
    • 84872678405 scopus 로고    scopus 로고
    • Positive modulation of osteogenesis- and osteoclastogenesis-related gene expression with strontium-containing microstructured Ti implants in rabbit cancellous bone
    • JW Park, YJ Kim, JH Jang, H Song Positive modulation of osteogenesis- and osteoclastogenesis-related gene expression with strontium-containing microstructured Ti implants in rabbit cancellous bone J Biomed Mater Res A 101 2013 298 306
    • (2013) J Biomed Mater Res A , vol.101 , pp. 298-306
    • Park, J.W.1    Kim, Y.J.2    Jang, J.H.3    Song, H.4
  • 16
    • 70350645482 scopus 로고    scopus 로고
    • Bioactive SrTiO(3) nanotube arrays: Strontium delivery platform on Ti-based osteoporotic bone implants
    • Y Xin, J Jiang, K Huo, T Hu, PK Chu Bioactive SrTiO(3) nanotube arrays: strontium delivery platform on Ti-based osteoporotic bone implants ACS Nano 3 2009 3228 3234
    • (2009) ACS Nano , vol.3 , pp. 3228-3234
    • Xin, Y.1    Jiang, J.2    Huo, K.3    Hu, T.4    Chu, P.K.5
  • 17
    • 84868131548 scopus 로고    scopus 로고
    • The osteogenic activity of strontium loaded titania nanotube arrays on titanium substrates
    • L Zhao, H Wang, K Huo, X Zhang, W Wang, Y Zhang et al. The osteogenic activity of strontium loaded titania nanotube arrays on titanium substrates Biomaterials 34 2013 19 29
    • (2013) Biomaterials , vol.34 , pp. 19-29
    • Zhao, L.1    Wang, H.2    Huo, K.3    Zhang, X.4    Wang, W.5    Zhang, Y.6
  • 19
    • 84870244945 scopus 로고    scopus 로고
    • Calcium phosphate phases integrated in silica/collagen nanocomposite xerogels enhance the bioactivity and ultimately manipulate the osteoblast/osteoclast ratio in a human co-culture model
    • S Heinemann, C Heinemann, S Wenisch, V Alt, H Worch, T Hanke Calcium phosphate phases integrated in silica/collagen nanocomposite xerogels enhance the bioactivity and ultimately manipulate the osteoblast/osteoclast ratio in a human co-culture model Acta Biomater 9 2013 4878 4888
    • (2013) Acta Biomater , vol.9 , pp. 4878-4888
    • Heinemann, S.1    Heinemann, C.2    Wenisch, S.3    Alt, V.4    Worch, H.5    Hanke, T.6
  • 21
    • 73349138928 scopus 로고    scopus 로고
    • Locally applied osteogenic predifferentiated progenitor cells are more effective than undifferentiated mesenchymal stem cells in the treatment of delayed bone healing
    • A Peters, D Toben, J Lienau, H Schell, HJ Bail, G Matziolis et al. Locally applied osteogenic predifferentiated progenitor cells are more effective than undifferentiated mesenchymal stem cells in the treatment of delayed bone healing Tissue Eng Part A 15 2009 2947 2954
    • (2009) Tissue Eng Part A , vol.15 , pp. 2947-2954
    • Peters, A.1    Toben, D.2    Lienau, J.3    Schell, H.4    Bail, H.J.5    Matziolis, G.6
  • 22
    • 84880817354 scopus 로고    scopus 로고
    • Applicability of ToF-SIMS for monitoring compositional changes in bone in a long-term animal model
    • A Henss, M Rohnke, T El Khassawna, P Govindarajan, G Schlewitz, C Heiss et al. Applicability of ToF-SIMS for monitoring compositional changes in bone in a long-term animal model J R Soc Interface 10 2013 20130332
    • (2013) J R Soc Interface , vol.10 , pp. 20130332
    • Henss, A.1    Rohnke, M.2    El Khassawna, T.3    Govindarajan, P.4    Schlewitz, G.5    Heiss, C.6
  • 23
    • 84882656554 scopus 로고    scopus 로고
    • Effects of multi-deficiencies-diet on bone parameters of peripheral bone in ovariectomized mature rat
    • T El Khassawna, W Bocker, P Govindarajan, N Schliefke, B Hurter, M Kampschulte et al. Effects of multi-deficiencies-diet on bone parameters of peripheral bone in ovariectomized mature rat PLoS One 8 2013 e71665
    • (2013) PLoS One , vol.8 , pp. e71665
    • El Khassawna, T.1    Bocker, W.2    Govindarajan, P.3    Schliefke, N.4    Hurter, B.5    Kampschulte, M.6
  • 25
    • 0023742941 scopus 로고
    • Clinical observations on fractures and heterotopic ossification in the spinal cord and traumatic brain injured populations
    • DE Garland Clinical observations on fractures and heterotopic ossification in the spinal cord and traumatic brain injured populations Clin Orthop Relat Res 1988 86 101
    • (1988) Clin Orthop Relat Res , pp. 86-101
    • Garland, D.E.1
  • 26
    • 67649648230 scopus 로고    scopus 로고
    • A novel model to study metaphyseal bone healing under defined biomechanical conditions
    • L Claes, A Veeser, M Gockelmann, U Simon, A Ignatius A novel model to study metaphyseal bone healing under defined biomechanical conditions Arch Orthop Trauma Surg 129 2009 923 928
    • (2009) Arch Orthop Trauma Surg , vol.129 , pp. 923-928
    • Claes, L.1    Veeser, A.2    Gockelmann, M.3    Simon, U.4    Ignatius, A.5
  • 27
    • 79958773712 scopus 로고    scopus 로고
    • Osteoprotegerin deficiency attenuates strontium-mediated inhibition of osteoclastogenesis and bone resorption
    • S Peng, XS Liu, G Zhou, Z Li, KD Luk, XE Guo et al. Osteoprotegerin deficiency attenuates strontium-mediated inhibition of osteoclastogenesis and bone resorption J Bone Miner Res 26 2011 1272 1282
    • (2011) J Bone Miner Res , vol.26 , pp. 1272-1282
    • Peng, S.1    Liu, X.S.2    Zhou, G.3    Li, Z.4    Luk, K.D.5    Guo, X.E.6
  • 28
    • 0028785711 scopus 로고
    • FDA Guidelines and animal models for osteoporosis
    • DD Thompson, HA Simmons, CM Pirie, HZ Ke FDA Guidelines and animal models for osteoporosis Bone 17 1995 125S 133S
    • (1995) Bone , vol.17 , pp. 125S-133S
    • Thompson, D.D.1    Simmons, H.A.2    Pirie, C.M.3    Ke, H.Z.4
  • 29
    • 44349159473 scopus 로고    scopus 로고
    • Effects of aging and dietary antler supplementation on the calcium-regulating hormones and bone status in ovariectomized SAMP8 mice
    • CC Chen, MH Liu, MF Wang, CC Chen Effects of aging and dietary antler supplementation on the calcium-regulating hormones and bone status in ovariectomized SAMP8 mice Chin J Physiol 50 2007 308 314
    • (2007) Chin J Physiol , vol.50 , pp. 308-314
    • Chen, C.C.1    Liu, M.H.2    Wang, M.F.3    Chen, C.C.4
  • 30
    • 0026005233 scopus 로고
    • Calcium supplementation reduces vertebral bone loss in perimenopausal women: A controlled trial in 248 women between 46 and 55 years of age
    • PJ Elders, JC Netelenbos, P Lips, FC van Ginkel, E Khoe, OR Leeuwenkamp et al. Calcium supplementation reduces vertebral bone loss in perimenopausal women: a controlled trial in 248 women between 46 and 55 years of age J Clin Endocrinol Metab 73 1991 533 540
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 533-540
    • Elders, P.J.1    Netelenbos, J.C.2    Lips, P.3    Van Ginkel, F.C.4    Khoe, E.5    Leeuwenkamp, O.R.6
  • 31
    • 5344238901 scopus 로고    scopus 로고
    • Histochemical evaluation for the biological effect of menatetrenone on metaphyseal trabeculae of ovariectomized rats
    • Y Asawa, N Amizuka, K Hara, M Kobayashi, M Aita, M Li et al. Histochemical evaluation for the biological effect of menatetrenone on metaphyseal trabeculae of ovariectomized rats Bone 35 2004 870 880
    • (2004) Bone , vol.35 , pp. 870-880
    • Asawa, Y.1    Amizuka, N.2    Hara, K.3    Kobayashi, M.4    Aita, M.5    Li, M.6
  • 33
    • 0034741829 scopus 로고    scopus 로고
    • 1alpha-Hydroxyvitamin D3 suppresses trabecular bone resorption by inhibiting osteoclastogenic potential in bone marrow cells after ovariectomy in mice
    • A Sakai, S Nishida, S Nishida, T Tsutsui, K Takeuchi, S Takeda et al. 1alpha-Hydroxyvitamin D3 suppresses trabecular bone resorption by inhibiting osteoclastogenic potential in bone marrow cells after ovariectomy in mice J Bone Miner Metab 19 2001 277 286
    • (2001) J Bone Miner Metab , vol.19 , pp. 277-286
    • Sakai, A.1    Nishida, S.2    Nishida, S.3    Tsutsui, T.4    Takeuchi, K.5    Takeda, S.6
  • 35
    • 0036130689 scopus 로고    scopus 로고
    • Vitamin D hormone inhibits osteoclastogenesis in vivo by decreasing the pool of osteoclast precursors in bone marrow
    • T Shibata, A Shira-Ishi, T Sato, T Masaki, A Masuda, A Hishiya et al. Vitamin D hormone inhibits osteoclastogenesis in vivo by decreasing the pool of osteoclast precursors in bone marrow J Bone Miner Res 17 2002 622 629
    • (2002) J Bone Miner Res , vol.17 , pp. 622-629
    • Shibata, T.1    Shira-Ishi, A.2    Sato, T.3    Masaki, T.4    Masuda, A.5    Hishiya, A.6
  • 36
    • 85047890899 scopus 로고    scopus 로고
    • Rodent animal models of delayed bone healing and non-union formation: A comprehensive review
    • discussion 12-14.
    • P Garcia, T Histing, JH Holstein, M Klein, MW Laschke, R Matthys et al. Rodent animal models of delayed bone healing and non-union formation: a comprehensive review Eur Cell Mater 26 2013 1 12 discussion 12-14.
    • (2013) Eur Cell Mater , vol.26 , pp. 1-12
    • Garcia, P.1    Histing, T.2    Holstein, J.H.3    Klein, M.4    Laschke, M.W.5    Matthys, R.6
  • 38
    • 37249048812 scopus 로고    scopus 로고
    • A novel transgenic mouse model to study the osteoblast lineage in vivo
    • C Maes, T Kobayashi, HM Kronenberg A novel transgenic mouse model to study the osteoblast lineage in vivo Ann N Y Acad Sci 1116 2007 149 164
    • (2007) Ann N y Acad Sci , vol.1116 , pp. 149-164
    • Maes, C.1    Kobayashi, T.2    Kronenberg, H.M.3
  • 40
    • 0042707618 scopus 로고    scopus 로고
    • S12911-2 reduces bone loss induced by short-term immobilization in rats
    • M Hott, P Deloffre, Y Tsouderos, PJ Marie S12911-2 reduces bone loss induced by short-term immobilization in rats Bone 33 2003 115 123
    • (2003) Bone , vol.33 , pp. 115-123
    • Hott, M.1    Deloffre, P.2    Tsouderos, Y.3    Marie, P.J.4
  • 41
    • 84890632651 scopus 로고    scopus 로고
    • Effects of strontium-doped calcium polyphosphate on angiogenic growth factors expression of co-culturing system in vitro and of host cell in vivo
    • Z Gu, H Xie, C Huang, H Peng, H Tan, L Li et al. Effects of strontium-doped calcium polyphosphate on angiogenic growth factors expression of co-culturing system in vitro and of host cell in vivo RSC Advances 4 2014 2783 2792
    • (2014) RSC Advances , vol.4 , pp. 2783-2792
    • Gu, Z.1    Xie, H.2    Huang, C.3    Peng, H.4    Tan, H.5    Li, L.6
  • 42
    • 83555164882 scopus 로고    scopus 로고
    • The intact strontium ranelate complex stimulates osteoblastogenesis and suppresses osteoclastogenesis by antagonizing NF-kappaB activation
    • M Yamaguchi, MN Weitzmann The intact strontium ranelate complex stimulates osteoblastogenesis and suppresses osteoclastogenesis by antagonizing NF-kappaB activation Mol Cell Biochem 359 2012 399 407
    • (2012) Mol Cell Biochem , vol.359 , pp. 399-407
    • Yamaguchi, M.1    Weitzmann, M.N.2
  • 43
    • 84896884747 scopus 로고    scopus 로고
    • The inhibitory effect of strontium-doped calcium polyphosphate particles on cytokines from macrophages and osteoblasts leading to aseptic loosening in vitro
    • C Huang, L Li, X Yu, Z Gu, X Zhang The inhibitory effect of strontium-doped calcium polyphosphate particles on cytokines from macrophages and osteoblasts leading to aseptic loosening in vitro Biomed Mater 9 2014 025010
    • (2014) Biomed Mater , vol.9 , pp. 025010
    • Huang, C.1    Li, L.2    Yu, X.3    Gu, Z.4    Zhang, X.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.