A new metaphyseal bone defect model in osteoporotic rats to study biomaterials for the enhancement of bone healing in osteoporotic fractures

Acta Biomaterialia

Volumn 9, Issue 6, 2013, Pages 7035-7042

  Alt, Volker ^a,b   Thormann, Ulrich ^a,b   Ray, Seemun ^b   Zahner, Daniel ^b   Dürselen, Lutz ^c   Lips, Katrin ^b   El Khassawna, Thaqif ^b   Heiss, Christian ^a,b   Riedrich, Alina ^b   Schlewitz, Gudrun ^a,b   Ignatius, Anita ^c   Kampschulte, Marian ^a   Von Dewitz, Helena ^a   Heinemann, Sascha ^d   Schnettler, Reinhard ^a,b   Langheinrich, Alexander ^a  

^a UNIVERSITY HOSPITAL GIESSEN   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c UNIVERSITY OF ULM   (Germany)

^d DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Biomaterials; Critical size defect; Fracture healing; Osteoporosis

Indexed keywords

BONE; COMPUTERIZED TOMOGRAPHY; DEFECTS; FRACTURE; FRACTURE TESTING; RATS; STIFFNESS;

ANIMAL MODEL; BENDING STIFFNESS; BONE DEFECT MODELS; BONE HEALING; CRITICAL SIZE; CRITICAL SIZE DEFECT; FRACTURE DEFECTS; FRACTURE HEALING; OSTEOPOROTIC; OSTEOPOROTIC FRACTURES;

DISEASES;

BIOMATERIAL; CALCIUM; COLECALCIFEROL; PHOSPHORUS; PHYTOESTROGEN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEFECT; BONE DENSITY; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR; FRACTURE HEALING; FRAGILITY FRACTURE; MEASUREMENT; METAPHYSIS; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSSIFICATION; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RAT; RIGIDITY; SPINE;

ANIMALIA; RATTUS;

EID: 84877714222     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2013.02.002     Document Type: Article

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