The osteogenic activity of strontium loaded titania nanotube arrays on titanium substrates

Biomaterials

Volumn 34, Issue 1, 2013, Pages 19-29

  Zhao, Lingzhou ^a   Wang, Hairong ^b   Huo, Kaifu ^b,c,d   Zhang, Xuming ^c   Wang, Wei ^a   Zhang, Yumei ^a   Wu, Zhifen ^a   Chu, Paul K ^c  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b WUHAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c CITY UNIVERSITY OF HONG KONG   (Hong Kong)

^d SHANGHAI INSTITUTE OF CERAMICS   (China)

Author keywords

Mesenchymal stem cells; Osteogenic differentiation; Protein adsorption; Strontium; Titania nanotubes

Indexed keywords

CELL CULTURE; FLOWCHARTING; GENE EXPRESSION; MINERALOGY; NANOTUBES; PHOSPHATASES; STEM CELLS; STRONTIUM; TITANIUM; TITANIUM DIOXIDE; YARN;

EXTRACELLULAR MATRICES; HYDROTHERMAL TREATMENTS; MESENCHYMAL STEM CELL; OSTEOGENESIS-RELATED GENES; OSTEOGENIC DIFFERENTIATION; PROTEIN ADSORPTION; TITANIA NANOTUBE ARRAYS; TITANIA NANOTUBES;

STRONTIUM COMPOUNDS;

ALKALINE PHOSPHATASE; BIOMATERIAL; BONE MORPHOGENETIC PROTEIN 2; COLLAGEN TYPE 1; GLUTAMATE DECARBOXYLASE; NANOMATERIAL; NANOTUBE; OSTEOCALCIN; STRONTIUM; TITANIA NANOTUBE; TITANIUM; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BONE DEVELOPMENT; BONE IMPLANT; BONE MINERALIZATION; BONE REGENERATION; CELL ADHESION; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; DRUG RELEASE; EXTRACELLULAR MATRIX; GENE EXPRESSION; MESENCHYMAL STEM CELL; NONHUMAN; OSTEOBLAST; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RECEPTOR UPREGULATION; SEPARATION TECHNIQUE;

RATTUS;

EID: 84868131548     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.09.041     Document Type: Article

References (47)

1. Tasso R., Fais F., Reverberi D., Tortelli F., Cancedda R. The recruitment of two consecutive and different waves of host stem/progenitor cells during the development of tissue-engineered bone in a murine model. Biomaterials 2010, 31:2121-2129.
2. Oh S., Brammer K.S., Li Y.S.J., Teng D., Engler A.J., Chien S., et al. Stem cell fate dictated solely by altered nanotube dimension. Proc Natl Acad Sci USA 2009, 106:2130-2135.
3. 2 nanotubes with different diameters on gene expression and osseointegration of implants in minipigs. Biomaterials 2011, 32:6900-6911.
4. Zhao L., Liu L., Wu Z., Zhang Y., Chu P.K. Effects of micropitted/nanotubular titania topographies on bone mesenchymal stem cell osteogenic differentiation. Biomaterials 2012, 33:2629-2641.
5. 2 nanotubes on titanium substrate. Acta Biomater 2007, 3:359-367.
6. Tzaphlidou M. The role of collagen in bone structure: an image processing approach. Micron 2005, 36:593-601.
7. Popat K.C., Eltgroth M., La Tempa T.J., Grimes C.A., Desai T.A. Titania nanotubes: a novel platform for drug-eluting coatings for medical implants?. Small 2007, 3:1878-1881.
8. Xin Y., Jiang J., Huo K., Hu T., Chu P.K. Bioactive SrTiO3 nanotube arrays: strontium delivery platform on Ti-based osteoporotic bone implants. ACS Nano 2009, 3:3228-3234.
9. Zhao L., Wang H., Huo K., Cui L., Zhang W., Ni H., et al. Antibacterial nano-structured titania coating incorporated with silver nanoparticles. Biomaterials 2011, 32:5706-5716.
10. Meunier P.J., Roux C., Seeman E., Ortolani S., Badurski J.E., Spector T.D., et al. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. N Engl J Med 2004, 350:459-468.
11. Seeman E., Vellas B., Benhamou C., Aquino J.P., Semler J., Kaufman J.M., et al. Strontium ranelate reduces the risk of vertebral and nonvertebral fractures in women eighty years of age and older. J Bone Miner Res 2006, 21:1113-1120.
12. Ammann P., Shen V., Robin B., Mauras Y., Bonjour J.P., Rizzoli R. Strontium ranelate improves bone resistance by increasing bone mass and improving architecture in intact female rats. J Bone Miner Res 2004, 19:2012-2020.
13. Marie P.J., Hott M., Modrowski D., De Pollak C., Guillemain J., Deloffre P., et al. An uncoupling agent containing strontium prevents bone loss by depressing bone resorption and maintaining bone formation in estrogen-deficient rats. J Bone Miner Res 1993, 8:607-615.
14. Bonnelye E., Chabadel A., Saltel F., Jurdic P. Dual effect of strontium ranelate: stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro. Bone 2008, 42:129-138.
15. Marie P.J. Strontium ranelate: a dual mode of action rebalancing bone turnover in favour of bone formation. Curr Opin Rheumatol 2006, 18(Suppl. 1):S11-S15.
16. Braux J., Velard F., Guillaume C., Bouthors S., Jallot E., Nedelec J.M., et al. A new insight into the dissociating effect of strontium on bone resorption and formation. Acta Biomater 2011, 7:2593-2603.
17. Coulombe J., Faure H., Robin B., Ruat M. In vitro effects of strontium ranelate on the extracellular calcium-sensing receptor. Biochem Biophys Res Commun 2004, 323:1184-1190.
18. Capuccini C., Torricelli P., Sima F., Boanini E., Ristoscu C., Bracci B., et al. Strontium-substituted hydroxyapatite coatings synthesized by pulsed-laser deposition: in vitro osteoblast and osteoclast response. Acta Biomater 2008, 4:1885-1893.
19. Yang F., Yang D., Tu J., Zheng Q., Cai L., Wang L. Strontium enhances osteogenic differentiation of mesenchymal stem cells and in vivo bone formation by activating Wnt/catenin signaling. Stem Cells 2011, 29:981-991.
20. Peng S., Zhou G., Luk K.D., Cheung K.M., Li Z., Lam W.M., et al. Strontium promotes osteogenic differentiation of mesenchymal stem cells through the Ras/MAPK signaling pathway. Cell Physiol Biochem 2009, 23:165-174.
21. Choudhary S., Halbout P., Alander C., Raisz L., Pilbeam C. Strontium ranelate promotes osteoblastic differentiation and mineralization of murine bone marrow stromal cells: involvement of prostaglandins. J Bone Miner Res 2007, 22:1002-1010.
22. Fournier C., Perrier A., Thomas M., Laroche N., Dumas V., Rattner A., et al. Reduction by strontium of the bone marrow adiposity in mice and repression of the adipogenic commitment of multipotent C3H10T1/2 cells. Bone 2012, 50:499-509.
23. Peng S., Liu X.S., Wang T., Li Z., Zhou G., Luk K.D., et al. In vivo anabolic effect of strontium on trabecular bone was associated with increased osteoblastogenesis of bone marrow stromal cells. J Orthop Res 2010, 28:1208-1214.
24. Hurtel-Lemaire A.S., Mentaverri R., Caudrillier A., Cournarie F., Wattel A., Kamel S., et al. The calcium-sensing receptor is involved in strontium ranelate-induced osteoclast apoptosis. New insights into the associated signaling pathways. J Biol Chem 2009, 284:575-584.
25. Li Y., Feng G., Gao Y., Luo E., Liu X., Hu J. Strontium ranelate treatment enhances hydroxyapatite-coated titanium screws fixation in osteoporotic rats. J Orthop Res 2010, 28:578-582.
26. Maimoun L., Brennan T.C., Badoud I., Dubois-Ferriere V., Rizzoli R., Ammann P. Strontium ranelate improves implant osseointegration. Bone 2010, 46:1436-1441.
27. Li Y., Li Q., Zhu S., Luo E., Li J., Feng G., et al. The effect of strontium-substituted hydroxyapatite coating on implant fixation in ovariectomized rats. Biomaterials 2010, 31:9006-9014.
28. Zreiqat H., Ramaswamy Y., Wu C., Paschalidis A., Lu Z., James B., et al. The incorporation of strontium and zinc into a calcium-silicon ceramic for bone tissue engineering. Biomaterials 2010, 31:3175-3184.
29. Gentleman E., Fredholm Y.C., Jell G., Lotfibakhshaiesh N., O'Donnell M.D., Hill R.G., et al. The effects of strontium-substituted bioactive glasses on osteoblasts and osteoclasts in vitro. Biomaterials 2010, 31:3949-3956.
30. Park J.W., Kim H.K., Kim Y.J., Jang J.H., Song H., Hanawa T. Osteoblast response and osseointegration of a Ti-6Al-4V alloy implant incorporating strontium. Acta Biomater 2010, 6:2843-2851.
31. Zhang W., Shen Y., Pan H., Lin K., Liu X., Darvell B.W., et al. Effects of strontium in modified biomaterials. Acta Biomater 2011, 7:800-808.
32. Qiu K., Zhao X.J., Wan C.X., Zhao C.S., Chen Y.W. Effect of strontium ions on the growth of ROS17/2.8 cells on porous calcium polyphosphate scaffolds. Biomaterials 2006, 27:1277-1286.
33. Zhao L., Mei S., Chu P.K., Zhang Y., Wu Z. The influence of hierarchical hybrid micro/nano-textured titanium surface with titania nanotubes on osteoblast functions. Biomaterials 2010, 31:5072-5082.
34. Zhao L., Mei S., Wang W., Chu P.K., Wu Z., Zhang Y. The role of sterilization in the cytocompatibility of titania nanotubes. Biomaterials 2010, 31:2055-2063.
35. Lord M.S., Foss M., Besenbacher F. Influence of nanoscale surface topography on protein adsorption and cellular response. Nano Today 2010, 5:66-78.
36. Anselme K. Osteoblast adhesion on biomaterials. Biomaterials 2000, 21:667-681.
37. Zhao L., Mei S., Wang W., Chu P.K., Zhang Y., Wu Z. Suppressed primary osteoblast functions on nanoporous titania surface. J Biomed Mater Res A 2011, 96:100-107.
38. Panzavolta S., Torricelli P., Sturba L., Bracci B., Giardino R., Bigi A. Setting properties and in vitro bioactivity of strontium-enriched gelatin-calcium phosphate bone cements. J Biomed Mater Res A 2008, 84:965-972.
39. Stein G.S., Lian J.B., Owen T.A. Relationship of cell growth to the regulation of tissue-specific gene expression during osteoblast differentiation. FASEB J 1990, 4:3111-3123.
40. Chung C.J., Long H.Y. Systematic strontium substitution in hydroxyapatite coatings on titanium via micro-arc treatment and their osteoblast/osteoclast responses. Acta Biomater 2011, 7:4081-4087.
41. McBeath R., Pirone D.M., Nelson C.M., Bhadriraju K., Chen C.S. Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment. Dev Cell 2004, 6:483-495.
42. Zhao L., Hu L., Huo K., Zhang Y., Wu Z., Chu P.K. Mechanism of cell repellence on quasi-aligned nanowire arrays on Ti alloy. Biomaterials 2010, 31:8341-8349.
43. Xue W., Moore J.L., Hosick H.L., Bose S., Bandyopadhyay A., Lu W.W., et al. Osteoprecursor cell response to strontium-containing hydroxyapatite ceramics. J Biomed Mater Res A 2006, 79:804-814.
44. Biggs M.J., Richards R.G., Dalby M.J. Nanotopographical modification: a regulator of cellular function through focal adhesions. Nanomedicine 2010, 6:619-633.
45. Biggs M.J., Richards R.G., Gadegaard N., Wilkinson C.D., Oreffo R.O., Dalby M.J. The use of nanoscale topography to modulate the dynamics of adhesion formation in primary osteoblasts and ERK/MAPK signalling in STRO-1+ enriched skeletal stem cells. Biomaterials 2009, 30:5094-5103.
46. Kilian K.A., Bugarija B., Lahn B.T., Mrksich M. Geometric cues for directing the differentiation of mesenchymal stem cells. Proc Natl Acad Sci USA 2010, 107:4872-4877.
47. Kaur G., Wang C., Sun J., Wang Q. The synergistic effects of multivalent ligand display and nanotopography on osteogenic differentiation of rat bone marrow stem cells. Biomaterials 2010, 31:5813-5824.