Phosphatase 2A Inhibition Affects Endoplasmic Reticulum and Mitochondria Homeostasis Via Cytoskeletal Alterations in Brain Endothelial Cells

Molecular Neurobiology

Volumn 54, Issue 1, 2017, Pages 154-168

  Plácido, Ana I ^a,b   Pereira, Cláudia M F ^a,b   Correira, Sónia C ^a,c   Carvalho, Cristina ^a,c   Oliveira, Catarina R ^a,b   Moreira, Paula I ^a,b  

^a UNIVERSITY OF COIMBRA   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF COIMBRA   (Portugal)

Author keywords

Cytoskeleton; Endoplasmic reticulum stress; Mitochondria dynamics; Protein phosphatases 2A

Indexed keywords

CALCIUM ION; CASPASE 3; CASPASE 9; ENDOPLASMIC RETICULUM OXIDOREDUCTASE 1ALPHA; F ACTIN; G ACTIN; GLUCOSE REGULATED PROTEIN 78; INITIATION FACTOR 2ALPHA; MITOCHONDRIAL PROTEIN; MITOFUSIN 1; MITOFUSIN 2; OKADAIC ACID; OXIDOREDUCTASE; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN DRP1; PROTEIN FIS1; PROTEIN OPA1; REACTIVE OXYGEN METABOLITE; SERINE; SIGMA 1 OPIATE RECEPTOR; TAU PROTEIN; THREONINE; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; ENZYME INHIBITOR; MYOSIN LIGHT CHAIN PHOSPHATASE;

ACTIN FILAMENT; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN BLOOD VESSEL; BRAIN CELL; BRAIN ENDOTHELIUM CELL; CALCIUM TRANSPORT; CELL ULTRASTRUCTURE; CELLULAR PARAMETERS; CONTROLLED STUDY; CYTOSKELETON; ENDOPLASMIC RETICULUM HOMEOSTASIS; ENDOPLASMIC RETICULUM STRESS; ENDOTHELIUM CELL; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; IN VITRO STUDY; MALE; MICROTUBULE; MITOCHONDRIAL DYNAMICS; MOUSE; NEUROPATHOLOGY; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RECEPTOR UPREGULATION; TRANSGENIC MOUSE; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; CELL LINE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECTS; ENDOPLASMIC RETICULUM; ENZYMOLOGY; HOMEOSTASIS; METABOLISM; MITOCHONDRION; PHYSIOLOGY;

ANIMALS; BRAIN; CELL LINE; CYTOSKELETON; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOPLASMIC RETICULUM; ENDOTHELIAL CELLS; ENZYME INHIBITORS; HOMEOSTASIS; MALE; MICE; MICE, TRANSGENIC; MITOCHONDRIA; MYOSIN-LIGHT-CHAIN PHOSPHATASE; OKADAIC ACID; RATS;

EID: 84953229269     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9640-1     Document Type: Article

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