메뉴 건너뛰기




Volumn 6, Issue , 2016, Pages

Distinct effects of β1 integrin on cell proliferation and cellular signaling in MDA-MB-231 breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; BETA1 INTEGRIN; EPIDERMAL GROWTH FACTOR RECEPTOR; PROTEIN KINASE INHIBITOR; PROTEIN SUBUNIT; QUINAZOLINE DERIVATIVE; TYRPHOSTIN;

EID: 84953227393     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep18430     Document Type: Article
Times cited : (52)

References (47)
  • 1
    • 0037145037 scopus 로고    scopus 로고
    • Integrins: Bidirectional, allosteric signaling machines
    • Hynes, R. O. Integrins: Bidirectional, allosteric signaling machines. Cell. 110, 673-687 (2002).
    • (2002) Cell. , vol.110 , pp. 673-687
    • Hynes, R.O.1
  • 2
    • 0030926774 scopus 로고    scopus 로고
    • Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogenactivated protein kinase through interactions with and activation of c-Src
    • Schlaepfer, D. D. & Hunter, T. Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogenactivated protein kinase through interactions with and activation of c-Src. J Biol Chem. 272, 13189-13195 (1997).
    • (1997) J Biol Chem. , vol.272 , pp. 13189-13195
    • Schlaepfer, D.D.1    Hunter, T.2
  • 3
    • 34249297624 scopus 로고    scopus 로고
    • Angiopoietin-2 stimulates breast cancer metastasis through the alpha(5) beta(1) integrin-mediated pathway
    • Imanishi, Y. et al. Angiopoietin-2 stimulates breast cancer metastasis through the alpha (5) beta (1) integrin-mediated pathway. Cancer Res. 67, 4254-4263 (2007).
    • (2007) Cancer Res. , vol.67 , pp. 4254-4263
    • Imanishi, Y.1
  • 4
    • 84892765398 scopus 로고    scopus 로고
    • Beta1 integrin: Critical path to antiangiogenic therapy resistance and beyond
    • Jahangiri, A., Aghi, M. K. & Carbonell, W. S. beta1 integrin: Critical path to antiangiogenic therapy resistance and beyond. Cancer Res. 74, 3-7 (2014).
    • (2014) Cancer Res. , vol.74 , pp. 3-7
    • Jahangiri, A.1    Aghi, M.K.2    Carbonell, W.S.3
  • 5
    • 0035899331 scopus 로고    scopus 로고
    • Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells
    • Aoudjit, F. & Vuori, K. Integrin signaling inhibits paclitaxel-induced apoptosis in breast cancer cells. Oncogene. 20, 4995-5004 (2001).
    • (2001) Oncogene. , vol.20 , pp. 4995-5004
    • Aoudjit, F.1    Vuori, K.2
  • 6
    • 85047286136 scopus 로고    scopus 로고
    • Beta1 and beta4 integrins: From breast development to clinical practice
    • Nistico, P., Di Modugno, F., Spada, S. & Bissell, M. J. beta1 and beta4 integrins: From breast development to clinical practice. Breast Cancer Res. 16, 459 (2014).
    • (2014) Breast Cancer Res. , vol.16 , pp. 459
    • Nistico, P.1    Di Modugno, F.2    Spada, S.3    Bissell, M.J.4
  • 7
    • 0032217084 scopus 로고    scopus 로고
    • Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: A different perspective in epithelial biology
    • Wang, F. et al. Reciprocal interactions between beta1-integrin and epidermal growth factor receptor in three-dimensional basement membrane breast cultures: A different perspective in epithelial biology. Proc Natl Acad Sci. USA. 95, 14821-14826 (1998).
    • (1998) Proc Natl Acad Sci. USA. , vol.95 , pp. 14821-14826
    • Wang, F.1
  • 8
    • 32944469169 scopus 로고    scopus 로고
    • Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo
    • Park, C. C. et al. Beta1 integrin inhibitory antibody induces apoptosis of breast cancer cells, inhibits growth, and distinguishes malignant from normal phenotype in three dimensional cultures and in vivo. Cancer Res. 66, 1526-1535 (2006).
    • (2006) Cancer Res. , vol.66 , pp. 1526-1535
    • Park, C.C.1
  • 9
    • 49249107671 scopus 로고    scopus 로고
    • Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts
    • Park, C. C., Zhang, H. J., Yao, E. S., Park, C. J. & Bissell, M. J. Beta1 integrin inhibition dramatically enhances radiotherapy efficacy in human breast cancer xenografts. Cancer Res. 68, 4398-4405 (2008).
    • (2008) Cancer Res. , vol.68 , pp. 4398-4405
    • Park, C.C.1    Zhang, H.J.2    Yao, E.S.3    Park, C.J.4    Bissell, M.J.5
  • 10
    • 0029051340 scopus 로고
    • Cellular growth and survival are mediated by beta 1 integrins in normal human breast epithelium but not in breast carcinoma
    • Howlett, A. R., Bailey, N., Damsky, C., Petersen, O. W. & Bissell, M. J. Cellular growth and survival are mediated by beta 1 integrins in normal human breast epithelium but not in breast carcinoma. J Cell Sci. 108, 1945-1957 (1995).
    • (1995) J Cell Sci. , vol.108 , pp. 1945-1957
    • Howlett, A.R.1    Bailey, N.2    Damsky, C.3    Petersen, O.W.4    Bissell, M.J.5
  • 11
    • 0030909050 scopus 로고    scopus 로고
    • Suppression of integrin activation: A novel function of a Ras/Raf-initiated MAP kinase pathway
    • Hughes, P. E. et al. Suppression of integrin activation: A novel function of a Ras/Raf-initiated MAP kinase pathway. Cell. 88, 521-530 (1997).
    • (1997) Cell. , vol.88 , pp. 521-530
    • Hughes, P.E.1
  • 12
    • 0036222549 scopus 로고    scopus 로고
    • Sensing the environment: A historical perspective on integrin signal transduction
    • Miranti, C. K. & Brugge, J. S. Sensing the environment: A historical perspective on integrin signal transduction. Nat Cell Biol. 4, E83-90 (2002).
    • (2002) Nat Cell Biol. , vol.4 , pp. 83-90
    • Miranti, C.K.1    Brugge, J.S.2
  • 13
    • 65349130129 scopus 로고    scopus 로고
    • Staged stromal extracellular 3D matrices differentially regulate breast cancer cell responses through PI3K and beta1-integrins
    • Castello-Cros, R., Khan, D. R., Simons, J., Valianou, M. & Cukierman, E. Staged stromal extracellular 3D matrices differentially regulate breast cancer cell responses through PI3K and beta1-integrins. BMC Cancer. 9, 94 (2009).
    • (2009) BMC Cancer. , vol.9 , pp. 94
    • Castello-Cros, R.1    Khan, D.R.2    Simons, J.3    Valianou, M.4    Cukierman, E.5
  • 14
    • 79960150078 scopus 로고    scopus 로고
    • Differences in integrin expression and signaling within human breast cancer cells
    • Taherian, A., Li, X., Liu, Y. & Haas, T. A. Differences in integrin expression and signaling within human breast cancer cells. BMC Cancer. 11, 293 (2011).
    • (2011) BMC Cancer. , vol.11 , pp. 293
    • Taherian, A.1    Li, X.2    Liu, Y.3    Haas, T.A.4
  • 15
    • 0037009820 scopus 로고    scopus 로고
    • Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts
    • Wang, F. et al. Phenotypic reversion or death of cancer cells by altering signaling pathways in three-dimensional contexts. J Natl Cancer Inst. 94, 1494-1503 (2002).
    • (2002) J Natl Cancer Inst. , vol.94 , pp. 1494-1503
    • Wang, F.1
  • 16
    • 0033067863 scopus 로고    scopus 로고
    • Matrix-degrading proteases and angiogenesis during development and tumor formation
    • Werb, Z., Vu, T. H., Rinkenberger, J. L. & Coussens, L. M. Matrix-degrading proteases and angiogenesis during development and tumor formation. APMIS. 107, 11-18 (1999).
    • (1999) APMIS. , vol.107 , pp. 11-18
    • Werb, Z.1    Vu, T.H.2    Rinkenberger, J.L.3    Coussens, L.M.4
  • 17
    • 72949119124 scopus 로고    scopus 로고
    • Integrins in cancer: Biological implications and therapeutic opportunities
    • Desgrosellier, J. S. & Cheresh, D. A. Integrins in cancer: Biological implications and therapeutic opportunities. Nat Rev Cancer. 10, 9-22 (2010).
    • (2010) Nat Rev Cancer. , vol.10 , pp. 9-22
    • Desgrosellier, J.S.1    Cheresh, D.A.2
  • 18
    • 34247626764 scopus 로고    scopus 로고
    • Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated Rac activation
    • Chen, X. et al. Integrin alpha1beta1 controls reactive oxygen species synthesis by negatively regulating epidermal growth factor receptor-mediated Rac activation. Mol Cell Biol. 27, 3313-3326 (2007).
    • (2007) Mol Cell Biol. , vol.27 , pp. 3313-3326
    • Chen, X.1
  • 19
    • 0033772308 scopus 로고    scopus 로고
    • FAK integrates growth-factor and integrin signals to promote cell migration
    • Sieg, D. J. et al. FAK integrates growth-factor and integrin signals to promote cell migration. Nat Cell Biol. 2, 249-256 (2000).
    • (2000) Nat Cell Biol. , vol.2 , pp. 249-256
    • Sieg, D.J.1
  • 22
    • 2342624080 scopus 로고    scopus 로고
    • EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
    • Paez, J. G. et al. EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy. Science. 304, 1497-1500 (2004).
    • (2004) Science. , vol.304 , pp. 1497-1500
    • Paez, J.G.1
  • 23
    • 2342471392 scopus 로고    scopus 로고
    • Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
    • Lynch, T. J. et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N Engl J Med. 350, 2129-2139 (2004).
    • (2004) N Engl J Med. , vol.350 , pp. 2129-2139
    • Lynch, T.J.1
  • 24
    • 46949101939 scopus 로고    scopus 로고
    • EGFR/HER2 in breast cancer: A biological approach for molecular diagnosis and therapy
    • Milanezi, F., Carvalho, S. & Schmitt, F. C. EGFR/HER2 in breast cancer: A biological approach for molecular diagnosis and therapy. Expert Rev Mol Diagn. 8, 417-434 (2008).
    • (2008) Expert Rev Mol Diagn. , vol.8 , pp. 417-434
    • Milanezi, F.1    Carvalho, S.2    Schmitt, F.C.3
  • 25
    • 33744750480 scopus 로고    scopus 로고
    • Basal-like breast carcinomas: Clinical outcome and response to chemotherapy
    • Banerjee, S. et al. Basal-like breast carcinomas: Clinical outcome and response to chemotherapy. J Clin Pathol. 59, 729-735 (2006).
    • (2006) J Clin Pathol. , vol.59 , pp. 729-735
    • Banerjee, S.1
  • 26
    • 84923102615 scopus 로고    scopus 로고
    • Src protein-tyrosine kinase structure, mechanism, and small molecule inhibitors
    • Roskoski, R., Jr. Src protein-tyrosine kinase structure, mechanism, and small molecule inhibitors. Pharmacol Res. 94, 9-25 (2015).
    • (2015) Pharmacol Res. , vol.94 , pp. 9-25
    • Roskoski, R.1
  • 27
    • 23844471971 scopus 로고    scopus 로고
    • Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface
    • Dawson, J. P. et al. Epidermal growth factor receptor dimerization and activation require ligand-induced conformational changes in the dimer interface. Mol Cell Biol 25, 7734-7742 (2005).
    • (2005) Mol Cell Biol , vol.25 , pp. 7734-7742
    • Dawson, J.P.1
  • 28
    • 0035893560 scopus 로고    scopus 로고
    • Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo
    • Moulder, S. L. et al. Epidermal growth factor receptor (HER1) tyrosine kinase inhibitor ZD1839 (Iressa) inhibits HER2/neu (erbB2)-overexpressing breast cancer cells in vitro and in vivo. Cancer Res. 61, 8887-8895 (2001).
    • (2001) Cancer Res. , vol.61 , pp. 8887-8895
    • Moulder, S.L.1
  • 29
    • 0037388251 scopus 로고    scopus 로고
    • ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells
    • Anido, J. et al. ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells. Clin Cancer Res. 9, 1274-1283 (2003).
    • (2003) Clin Cancer Res. , vol.9 , pp. 1274-1283
    • Anido, J.1
  • 30
    • 72749111836 scopus 로고    scopus 로고
    • Target-based therapies in breast cancer: Current status and future perspectives
    • Normanno, N. et al. Target-based therapies in breast cancer: Current status and future perspectives. Endocr Relat Cancer. 16, 675-702 (2009).
    • (2009) Endocr Relat Cancer. , vol.16 , pp. 675-702
    • Normanno, N.1
  • 31
    • 33646044696 scopus 로고    scopus 로고
    • Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase
    • Ellis, A. G. et al. Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase. Biochem Pharmacol. 71, 1422-1434 (2006).
    • (2006) Biochem Pharmacol. , vol.71 , pp. 1422-1434
    • Ellis, A.G.1
  • 32
    • 67949097338 scopus 로고    scopus 로고
    • Alpha6 beta4 integrin crosslinking induces EGFR clustering and promotes EGF-mediated Rho activation in breast cancer
    • Gilcrease, M. Z. et al. Alpha6 beta4 integrin crosslinking induces EGFR clustering and promotes EGF-mediated Rho activation in breast cancer. J Exp Clin Cancer Res 28, 67 (2009).
    • (2009) J Exp Clin Cancer Res , vol.28 , pp. 67
    • Gilcrease, M.Z.1
  • 33
    • 84897349287 scopus 로고    scopus 로고
    • Nuclear SIPA1 activates integrin beta1 promoter and promotes invasion of breast cancer cells
    • Zhang, Y. et al. Nuclear SIPA1 activates integrin beta1 promoter and promotes invasion of breast cancer cells. Oncogene. 34, 1451-1462 (2015).
    • (2015) Oncogene. , vol.34 , pp. 1451-1462
    • Zhang, Y.1
  • 34
    • 65949119310 scopus 로고    scopus 로고
    • How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer?
    • Mebratu, Y. & Tesfaigzi, Y. How ERK1/2 activation controls cell proliferation and cell death: Is subcellular localization the answer? Cell Cycle. 8, 1168-1175 (2009).
    • (2009) Cell Cycle. , vol.8 , pp. 1168-1175
    • Mebratu, Y.1    Tesfaigzi, Y.2
  • 35
    • 72249105509 scopus 로고    scopus 로고
    • Beta1-integrin circumvents the antiproliferative effects of trastuzumab in human epidermal growth factor receptor-2-positive breast cancer
    • Lesniak, D. et al. Beta1-integrin circumvents the antiproliferative effects of trastuzumab in human epidermal growth factor receptor-2-positive breast cancer. Cancer Res. 69, 8620-8628 (2009).
    • (2009) Cancer Res. , vol.69 , pp. 8620-8628
    • Lesniak, D.1
  • 36
    • 80052181422 scopus 로고    scopus 로고
    • Beta1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib
    • Huang, C. et al. beta1 integrin mediates an alternative survival pathway in breast cancer cells resistant to lapatinib. Breast Cancer Res. 13, R84, (2011).
    • (2011) Breast Cancer Res. , vol.13 , pp. 84
    • Huang, C.1
  • 37
    • 84930016629 scopus 로고    scopus 로고
    • Simultaneous beta1 integrin-EGFR targeting and radiosensitization of human head and neck cancer
    • Eke, I. et al. Simultaneous beta1 integrin-EGFR targeting and radiosensitization of human head and neck cancer. J Natl Cancer Inst. 107, 419 (2015).
    • (2015) J Natl Cancer Inst. , vol.107 , pp. 419
    • Eke, I.1
  • 38
    • 78650940402 scopus 로고    scopus 로고
    • The alpha(2) beta(1) integrin is a metastasis suppressor in mouse models and human cancer
    • Ramirez, N. E. et al. The alpha (2) beta (1) integrin is a metastasis suppressor in mouse models and human cancer. J Clin Invest. 121, 226-237 (2011).
    • (2011) J Clin Invest. , vol.121 , pp. 226-237
    • Ramirez, N.E.1
  • 39
    • 0031563765 scopus 로고    scopus 로고
    • Alpha 6 beta 4 and alpha 6 beta 1 integrins associate with ERBB-2 in human carcinoma cell lines
    • Falcioni, R. et al. Alpha 6 beta 4 and alpha 6 beta 1 integrins associate with ErbB-2 in human carcinoma cell lines. Exp Cell Res. 236, 76-85 (1997).
    • (1997) Exp Cell Res. , vol.236 , pp. 76-85
    • Falcioni, R.1
  • 40
    • 84866325625 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition under control: Global programs to regulate epithelial plasticity
    • Nieto, M. A. & Cano, A. The epithelial-mesenchymal transition under control: Global programs to regulate epithelial plasticity. Semin Cancer Biol. 22, 361-368 (2012).
    • (2012) Semin Cancer Biol. , vol.22 , pp. 361-368
    • Nieto, M.A.1    Cano, A.2
  • 41
    • 84878709832 scopus 로고    scopus 로고
    • Beta1 integrin regulates Arg to promote invadopodial maturation and matrix degradation
    • Beaty, B. T. et al. beta1 integrin regulates Arg to promote invadopodial maturation and matrix degradation. Mol Biol Cell. 24, 1661-1675 (2013).
    • (2013) Mol Biol Cell. , vol.24 , pp. 1661-1675
    • Beaty, B.T.1
  • 42
    • 0030936450 scopus 로고    scopus 로고
    • Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies
    • Weaver, V. M. et al. Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies. J Cell Biol. 137, 231-245 (1997).
    • (1997) J Cell Biol. , vol.137 , pp. 231-245
    • Weaver, V.M.1
  • 43
    • 84866168074 scopus 로고    scopus 로고
    • Distinct roles of talin and kindlin in regulating integrin alpha5beta1 function and trafficking
    • Margadant, C., Kreft, M., de Groot, D. J., Norman, J. C. & Sonnenberg, A. Distinct roles of talin and kindlin in regulating integrin alpha5beta1 function and trafficking. Curr Biol.CB 22, 1554-1563 (2012).
    • (2012) Curr Biol.CB , vol.22 , pp. 1554-1563
    • Margadant, C.1    Kreft, M.2    De Groot, D.J.3    Norman, J.C.4    Sonnenberg, A.5
  • 44
    • 84860879220 scopus 로고    scopus 로고
    • Roles of N-acetylglucosaminyltransferase III in epithelial-to-mesenchymal transition induced by transforming growth factor beta1 (TGF-beta1) in epithelial cell lines
    • Xu, Q. et al. Roles of N-acetylglucosaminyltransferase III in epithelial-to-mesenchymal transition induced by transforming growth factor beta1 (TGF-beta1) in epithelial cell lines. J Biol Chem. 287, 16563-16574 (2012).
    • (2012) J Biol Chem. , vol.287 , pp. 16563-16574
    • Xu, Q.1
  • 45
    • 84887010498 scopus 로고    scopus 로고
    • Genome engineering using the CRISPR-Cas9 system
    • Ran, F. A. et al. Genome engineering using the CRISPR-Cas9 system. Nat Protoc. 8, 2281-2308 (2013).
    • (2013) Nat Protoc. , vol.8 , pp. 2281-2308
    • Ran, F.A.1
  • 46
    • 84892765883 scopus 로고    scopus 로고
    • Genome-scale CRISPR-Cas9 knockout screening in human cells
    • Shalem, O. et al. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science. 343, 84-87 (2014).
    • (2014) Science. , vol.343 , pp. 84-87
    • Shalem, O.1
  • 47
    • 66449096361 scopus 로고    scopus 로고
    • N-glycosylation of the I-like domain of beta1 integrin is essential for beta1 integrin expression and biological function: Identification of the minimal N-glycosylation requirement for alpha 5 beta1
    • Isaji, T., Sato, Y., Fukuda, T. & Gu, J. N-glycosylation of the I-like domain of beta1 integrin is essential for beta1 integrin expression and biological function: Identification of the minimal N-glycosylation requirement for alpha 5 beta1. The J Biol Chem. 284, 12207-12216 (2009).
    • (2009) The J Biol Chem. , vol.284 , pp. 12207-12216
    • Isaji, T.1    Sato, Y.2    Fukuda, T.3    Gu, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.