-
1
-
-
0037214253
-
Pharmacopathology: A new spin on an old idea
-
Schnitt SJ. Pharmacopathology: a new spin on an old idea. Am. J. Surg. Pathol. 27(1), 121-123(2003).
-
(2003)
Am. J. Surg. Pathol
, vol.27
, Issue.1
, pp. 121-123
-
-
Schnitt, S.J.1
-
2
-
-
5644252971
-
Molecular approach to breast cancer treatment
-
Yarden Y, Baselga J, Miles D. Molecular approach to breast cancer treatment. Semin. Oncol. 31(5 Suppl. 10), 6-13 (2004).
-
(2004)
Semin. Oncol
, vol.31
, Issue.5 SUPPL. 10
, pp. 6-13
-
-
Yarden, Y.1
Baselga, J.2
Miles, D.3
-
3
-
-
36549055697
-
Will targeted therapy hold its promise? An evidence-based review
-
Murdoch D, Sager J. Will targeted therapy hold its promise? An evidence-based review. Curr. Opin. Oncol. 20(1), 104-111 (2008).
-
(2008)
Curr. Opin. Oncol
, vol.20
, Issue.1
, pp. 104-111
-
-
Murdoch, D.1
Sager, J.2
-
4
-
-
34447299692
-
EGFR targeting of solid tumors
-
Rocha-Lima CM, Soares HP, Raez LE, Singal R. EGFR targeting of solid tumors. Cancer Control 14(3), 295-304 (2007).
-
(2007)
Cancer Control
, vol.14
, Issue.3
, pp. 295-304
-
-
Rocha-Lima, C.M.1
Soares, H.P.2
Raez, L.E.3
Singal, R.4
-
5
-
-
33746782976
-
Adjuvant trastuzumab therapy for HER2-overexpressing breast cancer: What we know and what we still need to learn
-
Piccart-Gebhart MJ. Adjuvant trastuzumab therapy for HER2-overexpressing breast cancer: what we know and what we still need to learn. Eur. J. Cancer 42(12), 1715-1719 (2006).
-
(2006)
Eur. J. Cancer
, vol.42
, Issue.12
, pp. 1715-1719
-
-
Piccart-Gebhart, M.J.1
-
6
-
-
5644302245
-
Future options with trastuzumab for primary systemic and adjuvant therapy
-
Baselga J, Gianni L, Geyer C et al. Future options with trastuzumab for primary systemic and adjuvant therapy. Semin. Oncol. 31(5 Suppl. 10), 51-57 (2004).
-
(2004)
Semin. Oncol
, vol.31
, Issue.5 SUPPL. 10
, pp. 51-57
-
-
Baselga, J.1
Gianni, L.2
Geyer, C.3
-
7
-
-
33847718214
-
The EGF receptor family: Spearheading a merger of signaling and therapeutics
-
Bublil EM, Yarden Y The EGF receptor family: spearheading a merger of signaling and therapeutics. Curr. Opin. Cell. Biol. 19(2), 124-134 (2007).
-
(2007)
Curr. Opin. Cell. Biol
, vol.19
, Issue.2
, pp. 124-134
-
-
Bublil, E.M.1
Yarden, Y.2
-
8
-
-
0041629450
-
Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
-
Mendelsohn J, Baselga J. Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J. Clin. Oncol. 21(14), 2787-2799 (2003).
-
(2003)
J. Clin. Oncol
, vol.21
, Issue.14
, pp. 2787-2799
-
-
Mendelsohn, J.1
Baselga, J.2
-
9
-
-
34547854801
-
The oncogene HER2: Its signaling and transforming functions and its role in human cancer pathogenesis
-
Moasser MM. The oncogene HER2: its signaling and transforming functions and its role in human cancer pathogenesis. Oncogene 26(45), 6469-6487 (2007).
-
(2007)
Oncogene
, vol.26
, Issue.45
, pp. 6469-6487
-
-
Moasser, M.M.1
-
10
-
-
34547922452
-
Targeting the function of the HER2 oncogene in human cancer therapeutics
-
Moasser MM. Targeting the function of the HER2 oncogene in human cancer therapeutics. Oncogene 26(46), 6577-6592 (2007).
-
(2007)
Oncogene
, vol.26
, Issue.46
, pp. 6577-6592
-
-
Moasser, M.M.1
-
11
-
-
34249672864
-
Trastuzumab: Triumphs and tribulations
-
Nahta R, Esteva FJ. Trastuzumab: triumphs and tribulations. Oncogene 26(25), 3637-3643 (2007).
-
(2007)
Oncogene
, vol.26
, Issue.25
, pp. 3637-3643
-
-
Nahta, R.1
Esteva, F.J.2
-
12
-
-
33748115504
-
Use of trastuzumab for the treatment of early stage breast cancer
-
Braga S, dal Lago L, Bernard C, Cardoso F, Piccart M. Use of trastuzumab for the treatment of early stage breast cancer. Expert Rev. Anticancer Ther. 6(8), 1153-1164(2006).
-
(2006)
Expert Rev. Anticancer Ther
, vol.6
, Issue.8
, pp. 1153-1164
-
-
Braga, S.1
dal Lago, L.2
Bernard, C.3
Cardoso, F.4
Piccart, M.5
-
13
-
-
26844559765
-
Trastuzumab in the treatment of breast cancer
-
Hortobagyi GN. Trastuzumab in the treatment of breast cancer. N. Engl. J. Med. 353(16), 1734-1736(2005).
-
(2005)
N. Engl. J. Med
, vol.353
, Issue.16
, pp. 1734-1736
-
-
Hortobagyi, G.N.1
-
14
-
-
44849117186
-
Estimating the magnitude of trastuzumab effects within patient subgroups in the HERA trial
-
Untch M, Gelber RD, Jackisch C et al. Estimating the magnitude of trastuzumab effects within patient subgroups in the HERA trial. Ann. Oncol. 19(6), 1090-1096 (2008).
-
(2008)
Ann. Oncol
, vol.19
, Issue.6
, pp. 1090-1096
-
-
Untch, M.1
Gelber, R.D.2
Jackisch, C.3
-
15
-
-
41649083764
-
Cardiac safety analysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the North Central Cancer Treatment Group N9831 adjuvant breast cancer trial
-
Perez EA, Suman VJ, Davidson NE et al. Cardiac safety analysis of doxorubicin and cyclophosphamide followed by paclitaxel with or without trastuzumab in the North Central Cancer Treatment Group N9831 adjuvant breast cancer trial. J. Clin. Oncol. 26(8), 1231-1238 (2008).
-
(2008)
J. Clin. Oncol
, vol.26
, Issue.8
, pp. 1231-1238
-
-
Perez, E.A.1
Suman, V.J.2
Davidson, N.E.3
-
16
-
-
33947317453
-
BCIRG 006: 2nd interim analysis Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (ACT) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (ACTH) with docetaxel, carboplatin and trastuzumab (TCH) in HER2neu positive early breast cancer patients
-
Abstract 52
-
Slamon D, Eirmann W, Robert N et al. BCIRG 006: 2nd interim analysis Phase III randomized trial comparing doxorubicin and cyclophosphamide followed by docetaxel (ACT) with doxorubicin and cyclophosphamide followed by docetaxel and trastuzumab (ACTH) with docetaxel, carboplatin and trastuzumab (TCH) in HER2neu positive early breast cancer patients. Breast Cancer Res. Treat. 100(Suppl. 1) (2006) (Abstract 52).
-
(2006)
Breast Cancer Res. Treat
, Issue.SUPPL. 1
, pp. 100
-
-
Slamon, D.1
Eirmann, W.2
Robert, N.3
-
17
-
-
33344458106
-
Herceptin and the heart - a molecular modifier of cardiac failure
-
Chien KR. Herceptin and the heart - a molecular modifier of cardiac failure. N. Engl. J. Med. 354(8), 789-790 (2006).
-
(2006)
N. Engl. J. Med
, vol.354
, Issue.8
, pp. 789-790
-
-
Chien, K.R.1
-
18
-
-
33847147313
-
American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer
-
Wolff AC, Hammond ME, Schwartz JN et al. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J. Clin. Oncol. 25(1), 118-145 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.1
, pp. 118-145
-
-
Wolff, A.C.1
Hammond, M.E.2
Schwartz, J.N.3
-
19
-
-
15544382365
-
Assessment of the HER2 status in breast cancer by fluorescence in situ hybridization: A technical review with interpretive guidelines
-
Hicks DG, Tubbs RR. Assessment of the HER2 status in breast cancer by fluorescence in situ hybridization: a technical review with interpretive guidelines. Hum. Pathol. 36(3), 250-261 (2005).
-
(2005)
Hum. Pathol
, vol.36
, Issue.3
, pp. 250-261
-
-
Hicks, D.G.1
Tubbs, R.R.2
-
20
-
-
4143150688
-
Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma
-
Nielsen TO, Hsu FD, Jensen K et al. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin. Cancer Res. 10(16), 5367-5374(2004).
-
(2004)
Clin. Cancer Res
, vol.10
, Issue.16
, pp. 5367-5374
-
-
Nielsen, T.O.1
Hsu, F.D.2
Jensen, K.3
-
21
-
-
33846587923
-
The basal subtype of breast carcinomas may represent the group of breast tumors that could benefit from EGFR-targeted therapies
-
Siziopikou KP, Cobleigh M. The basal subtype of breast carcinomas may represent the group of breast tumors that could benefit from EGFR-targeted therapies. Breast 16(1), 104-107 (2007).
-
(2007)
Breast
, vol.16
, Issue.1
, pp. 104-107
-
-
Siziopikou, K.P.1
Cobleigh, M.2
-
22
-
-
2342624080
-
EGFR mutations in lung cancer: Correlation with clinical response to gefitinib therapy
-
Paez JG, Janne PA, Lee JC et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304(5676), 1497-1500 (2004).
-
(2004)
Science
, vol.304
, Issue.5676
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
-
23
-
-
27244451321
-
Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer
-
Takano T, Ohe Y, Sakamoto H et al. Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer. J. Clin. Oncol. 23(28), 6829-6837 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.28
, pp. 6829-6837
-
-
Takano, T.1
Ohe, Y.2
Sakamoto, H.3
-
24
-
-
2342471392
-
Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib
-
Lynch TJ, Bell DW, Sordella R et al. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib. N. Engl. J. Med. 350(21), 2129-2139 (2004).
-
(2004)
N. Engl. J. Med
, vol.350
, Issue.21
, pp. 2129-2139
-
-
Lynch, T.J.1
Bell, D.W.2
Sordella, R.3
-
25
-
-
41549097718
-
EGFR FISH assay predicts for response to cetuximab in chemotherapy refractory colorectal cancer patients
-
Cappuzzo F, Finocchiaro G, Rossi E et al. EGFR FISH assay predicts for response to cetuximab in chemotherapy refractory colorectal cancer patients. Ann. Oncol. 19(4), 717-723 (2008).
-
(2008)
Ann. Oncol
, vol.19
, Issue.4
, pp. 717-723
-
-
Cappuzzo, F.1
Finocchiaro, G.2
Rossi, E.3
-
26
-
-
1342281177
-
Evaluation of epidermal growth factor receptor (EGFR) by chromogenic in situ hybridization (CISH) and immunohistochemistry (IHC) in archival gliomas using bright-field microscopy
-
Marquez A, Wu R, Zhao J, Tao J, Shi Z. Evaluation of epidermal growth factor receptor (EGFR) by chromogenic in situ hybridization (CISH) and immunohistochemistry (IHC) in archival gliomas using bright-field microscopy. Diagn.Mol. Pathol. 13(1), 1-8 (2004).
-
(2004)
Diagn.Mol. Pathol
, vol.13
, Issue.1
, pp. 1-8
-
-
Marquez, A.1
Wu, R.2
Zhao, J.3
Tao, J.4
Shi, Z.5
-
27
-
-
0037429779
-
The deaf and the dumb: The biology of ErbB-2 and ErbB-3
-
Citri A, Skaria KB, Yarden Y The deaf and the dumb: the biology of ErbB-2 and ErbB-3. Exp. Cell. Res. 284(1), 54-65 (2003).
-
(2003)
Exp. Cell. Res
, vol.284
, Issue.1
, pp. 54-65
-
-
Citri, A.1
Skaria, K.B.2
Yarden, Y.3
-
28
-
-
18344390418
-
ERBB receptors and cancer: The complexity of targeted inhibitors
-
Hynes NE, Lane HA. ERBB receptors and cancer: the complexity of targeted inhibitors. Nat. Rev. Cancer 5(5), 341-354 (2005).
-
(2005)
Nat. Rev. Cancer
, vol.5
, Issue.5
, pp. 341-354
-
-
Hynes, N.E.1
Lane, H.A.2
-
29
-
-
0037429727
-
-
Stern DE ErbBs in mammary development
-
Stern DE ErbBs in mammary development. Exp. Cell. Res. 284(1), 89-98 (2003).
-
(2003)
Exp. Cell. Res
, vol.284
, Issue.1
, pp. 89-98
-
-
-
30
-
-
3042611780
-
Oncogenic growth factor receptors: Implications for signal transduction therapy
-
Mosesson Y, Yarden Y Oncogenic growth factor receptors: implications for signal transduction therapy. Semin. Cancer Biol. 14(4), 262-270 (2004).
-
(2004)
Semin. Cancer Biol
, vol.14
, Issue.4
, pp. 262-270
-
-
Mosesson, Y.1
Yarden, Y.2
-
31
-
-
0042029746
-
Muc4/sialomucin complex, the intramembrane ErbB2 ligand, translocates ErbB2 to the apical surface in polarized epithelial cells
-
Ramsauer VP, Carraway CA, Salas PJ, Carraway KL. Muc4/sialomucin complex, the intramembrane ErbB2 ligand, translocates ErbB2 to the apical surface in polarized epithelial cells. J. Biol. Chem. 278(32), 30142-30147 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, Issue.32
, pp. 30142-30147
-
-
Ramsauer, V.P.1
Carraway, C.A.2
Salas, P.J.3
Carraway, K.L.4
-
32
-
-
0042307325
-
The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation
-
Holbro T, Beerli RR, Maurer F et al. The ErbB2/ErbB3 heterodimer functions as an oncogenic unit: ErbB2 requires ErbB3 to drive breast tumor cell proliferation. Proc. Natl Acad. Sci. USA 100(15), 8933-8938 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, Issue.15
, pp. 8933-8938
-
-
Holbro, T.1
Beerli, R.R.2
Maurer, F.3
-
33
-
-
34547601870
-
A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration
-
Katz M, Amit I, Citri A et al. A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration. Nat. Cell Biol. 9(8), 961-969 (2007).
-
(2007)
Nat. Cell Biol
, vol.9
, Issue.8
, pp. 961-969
-
-
Katz, M.1
Amit, I.2
Citri, A.3
-
34
-
-
0038575385
-
Expression of the HER1-4 family of receptor tyrosine kinases in breast cancer
-
Witton CJ, Reeves JR, Going JJ, Cooke TG, Bartlett JM. Expression of the HER1-4 family of receptor tyrosine kinases in breast cancer. J. Pathol. 200(3), 290-297 (2003).
-
(2003)
J. Pathol
, vol.200
, Issue.3
, pp. 290-297
-
-
Witton, C.J.1
Reeves, J.R.2
Going, J.J.3
Cooke, T.G.4
Bartlett, J.M.5
-
35
-
-
0031730476
-
Expression of c-erbB3 protein in primary breast carcinomas
-
Naidu R, Yadav M, Nair S, Kutty MK. Expression of c-erbB3 protein in primary breast carcinomas. Br. J. Cancer 78(10), 1385-1390 (1998).
-
(1998)
Br. J. Cancer
, vol.78
, Issue.10
, pp. 1385-1390
-
-
Naidu, R.1
Yadav, M.2
Nair, S.3
Kutty, M.K.4
-
36
-
-
0033747558
-
Prognostic value of the type I growth factor receptors in a large series of human primary breast cancers quantified with a real-time reverse transcription-polymerase chain reaction assay
-
Pawlowski V, Revillion F, Hebbar M, Hornez L, Peyrat JP Prognostic value of the type I growth factor receptors in a large series of human primary breast cancers quantified with a real-time reverse transcription-polymerase chain reaction assay. Clin. Cancer Res. 6(11), 4217-4225 (2000).
-
(2000)
Clin. Cancer Res
, vol.6
, Issue.11
, pp. 4217-4225
-
-
Pawlowski, V.1
Revillion, F.2
Hebbar, M.3
Hornez, L.4
Peyrat, J.P.5
-
37
-
-
0036145181
-
EGFR family expression in breast carcinomas. c-erbB-2 and c-erbB-4 receptors have different effects on survival
-
Suo Z, Risberg B, Kalsson MG et al. EGFR family expression in breast carcinomas. c-erbB-2 and c-erbB-4 receptors have different effects on survival. J. Pathol. 196(1), 17-25 (2002).
-
(2002)
J. Pathol
, vol.196
, Issue.1
, pp. 17-25
-
-
Suo, Z.1
Risberg, B.2
Kalsson, M.G.3
-
38
-
-
37849046940
-
ErbB/HER ligands in human breast cancer and relationships with their receptors, the bio-pathological features and prognosis
-
Revillion F, Lhotellier V, Hornez L, Bonneterre J, Peyrat JP. ErbB/HER ligands in human breast cancer and relationships with their receptors, the bio-pathological features and prognosis. Ann. Oncol. 19(1), 73-80 (2008).
-
(2008)
Ann. Oncol
, vol.19
, Issue.1
, pp. 73-80
-
-
Revillion, F.1
Lhotellier, V.2
Hornez, L.3
Bonneterre, J.4
Peyrat, J.P.5
-
39
-
-
34547871259
-
Targeting HER proteins in cancer therapy and the role of the non-target HER3
-
Hsieh AC, Moasser MM. Targeting HER proteins in cancer therapy and the role of the non-target HER3. Br. J. Cancer 97(4), 453-457 (2007).
-
(2007)
Br. J. Cancer
, vol.97
, Issue.4
, pp. 453-457
-
-
Hsieh, A.C.1
Moasser, M.M.2
-
40
-
-
0016000929
-
Epidermal growth factor: Chemical and biological characterization
-
Cohen S, Taylor JM. Epidermal growth factor: chemical and biological characterization. Recent Prog. Horm. Res. 30(0), 533-550(1974).
-
(1974)
Recent Prog. Horm. Res
, vol.30
, Issue.0
, pp. 533-550
-
-
Cohen, S.1
Taylor, J.M.2
-
41
-
-
0037285971
-
Growth factor receptors in breast cancer: Potential for therapeutic intervention
-
Nahta R, Hortobagyi GN, Esteva FJ. Growth factor receptors in breast cancer: potential for therapeutic intervention. Oncologist 8(1), 5-17 (2003).
-
(2003)
Oncologist
, vol.8
, Issue.1
, pp. 5-17
-
-
Nahta, R.1
Hortobagyi, G.N.2
Esteva, F.J.3
-
42
-
-
0010066582
-
A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma
-
Semba K, Kamata N, Toyoshima K, Yamamoto T A v-erbB-related protooncogene, c-erbB-2, is distinct from the c-erbB-1/epidermal growth factor-receptor gene and is amplified in a human salivary gland adenocarcinoma. Proc. Natl Acad. Sci. USA 82(19), 6497-6501 (1985).
-
(1985)
Proc. Natl Acad. Sci. USA
, vol.82
, Issue.19
, pp. 6497-6501
-
-
Semba, K.1
Kamata, N.2
Toyoshima, K.3
Yamamoto, T.4
-
43
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 100(1), 57-70 (2000).
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
44
-
-
0038461104
-
Epidermal growth factor receptor (EGFR) as a target in cancer therapy: Understanding the role of receptor expression and other molecular determinants that could influence the response to anti-EGFR drugs
-
Ciardiello F, Tortora G. Epidermal growth factor receptor (EGFR) as a target in cancer therapy: understanding the role of receptor expression and other molecular determinants that could influence the response to anti-EGFR drugs. Eur. J. Cancer 39(10), 1348-1354 (2003).
-
(2003)
Eur. J. Cancer
, vol.39
, Issue.10
, pp. 1348-1354
-
-
Ciardiello, F.1
Tortora, G.2
-
45
-
-
33745761030
-
Amplification of the epidermal growth factor receptor in astrocytic tumours by chromogenic in situ hybridization: Association with clinicopathological features and patient survival
-
Jarvela S, Helin H, Haapasalo J et al. Amplification of the epidermal growth factor receptor in astrocytic tumours by chromogenic in situ hybridization: association with clinicopathological features and patient survival. Neuropathol Appl. Neurobiol. 32(4), 441-450 (2006).
-
(2006)
Neuropathol Appl. Neurobiol
, vol.32
, Issue.4
, pp. 441-450
-
-
Jarvela, S.1
Helin, H.2
Haapasalo, J.3
-
46
-
-
4544258999
-
EGFR and EGFRvIII expression in primary breast cancer and cell lines
-
Rae JM, Scheys JO, Clark KM et al. EGFR and EGFRvIII expression in primary breast cancer and cell lines. Breast Cancer Res. Treat. 87(1), 87-95 (2004).
-
(2004)
Breast Cancer Res. Treat
, vol.87
, Issue.1
, pp. 87-95
-
-
Rae, J.M.1
Scheys, J.O.2
Clark, K.M.3
-
47
-
-
35348848403
-
Prognostic significance of overexpression and phosphorylation of epidermal growth factor receptor (EGFR) and the presence of truncated EGFRvIII in locoregionally advanced breast cancer
-
Nieto Y Nawaz F, Jones RB, Shpall EJ, Nawaz S. Prognostic significance of overexpression and phosphorylation of epidermal growth factor receptor (EGFR) and the presence of truncated EGFRvIII in locoregionally advanced breast cancer. J. Clin. Oncol. 25(28), 4405-4413 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.28
, pp. 4405-4413
-
-
Nieto, Y.1
Nawaz, F.2
Jones, R.B.3
Shpall, E.J.4
Nawaz, S.5
-
48
-
-
1842591231
-
Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases
-
Marmor MD, Yarden Y Role of protein ubiquitylation in regulating endocytosis of receptor tyrosine kinases. Oncogene 23(11), 2057-2070 (2004).
-
(2004)
Oncogene
, vol.23
, Issue.11
, pp. 2057-2070
-
-
Marmor, M.D.1
Yarden, Y.2
-
49
-
-
0035895664
-
Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases
-
Waterman H, Yarden Y Molecular mechanisms underlying endocytosis and sorting of ErbB receptor tyrosine kinases. FEBS Lett. 490(3), 142-152 (2001).
-
(2001)
FEBS Lett
, vol.490
, Issue.3
, pp. 142-152
-
-
Waterman, H.1
Yarden, Y.2
-
50
-
-
33646394318
-
Disruption of the Y-box binding protein-1 results in suppression of the epidermal growth factor receptor and HER-2
-
Wu J, Lee C, Yokom D et al. Disruption of the Y-box binding protein-1 results in suppression of the epidermal growth factor receptor and HER-2. Cancer Res. 66(9), 4872-4879 (2006).
-
(2006)
Cancer Res
, vol.66
, Issue.9
, pp. 4872-4879
-
-
Wu, J.1
Lee, C.2
Yokom, D.3
-
51
-
-
18844457596
-
Y-box-binding protein 1 confers EGF independence to human mammary epithelial cells
-
Berquin IM, Pang B, Dziubinski ML et al. Y-box-binding protein 1 confers EGF independence to human mammary epithelial cells. Oncogene 24(19), 3177-3186 (2005).
-
(2005)
Oncogene
, vol.24
, Issue.19
, pp. 3177-3186
-
-
Berquin, I.M.1
Pang, B.2
Dziubinski, M.L.3
-
52
-
-
33750627353
-
Mutational analysis of the HER2 gene in lung tumors from Caucasian patients: Mutations are mainly present in adenocarcinomas with bronchioloalveolar features
-
Buttitta F, Barassi F, Fresu G et al. Mutational analysis of the HER2 gene in lung tumors from Caucasian patients: mutations are mainly present in adenocarcinomas with bronchioloalveolar features. Int. J. Cancer 119(11), 2586-2591 (2006).
-
(2006)
Int. J. Cancer
, vol.119
, Issue.11
, pp. 2586-2591
-
-
Buttitta, F.1
Barassi, F.2
Fresu, G.3
-
53
-
-
20144386787
-
Somatic mutations of the HER2 kinase domain in lung adenocarcinomas
-
Shigematsu H, Takahashi T, Nomura M et al. Somatic mutations of the HER2 kinase domain in lung adenocarcinomas. Cancer Res. 65(5), 1642-1646 (2005).
-
(2005)
Cancer Res
, vol.65
, Issue.5
, pp. 1642-1646
-
-
Shigematsu, H.1
Takahashi, T.2
Nomura, M.3
-
54
-
-
21644441867
-
Yin Yang 1 cooperates with activator protein 2 to stimulate ERBB2 gene expression in mammary cancer cells
-
Begon DY, Delacroix L, Vernimmen D, Jackers P, Winkler R. Yin Yang 1 cooperates with activator protein 2 to stimulate ERBB2 gene expression in mammary cancer cells. J. Biol. Chem. 280(26), 24428-24434 (2005).
-
(2005)
J. Biol. Chem
, vol.280
, Issue.26
, pp. 24428-24434
-
-
Begon, D.Y.1
Delacroix, L.2
Vernimmen, D.3
Jackers, P.4
Winkler, R.5
-
55
-
-
0141841783
-
Different mechanisms are implicated in ERBB2 gene overexpression in breast and in other cancers
-
Vernimmen D, Gueders M, Pisvin S, Delvenne P Winkler R. Different mechanisms are implicated in ERBB2 gene overexpression in breast and in other cancers. Br. J. Cancer 89(5), 899-906 (2003).
-
(2003)
Br. J. Cancer
, vol.89
, Issue.5
, pp. 899-906
-
-
Vernimmen, D.1
Gueders, M.2
Pisvin, S.3
Delvenne, P.4
Winkler, R.5
-
56
-
-
1942431966
-
The achilles heel of ErbB-2/HER2: Regulation by the Hsp90 chaperone machine and potential for pharmacological intervention
-
Citri A, Kochupurakkal BS, Yarden Y The achilles heel of ErbB-2/HER2: regulation by the Hsp90 chaperone machine and potential for pharmacological intervention. Cell Cycle 3(1), 51-60 (2004).
-
(2004)
Cell Cycle
, vol.3
, Issue.1
, pp. 51-60
-
-
Citri, A.1
Kochupurakkal, B.S.2
Yarden, Y.3
-
57
-
-
12144266330
-
Hsp90 restrains ErbB-2/HER2 signalling by limiting heterodimer formation
-
512, 1165-1170
-
Citri A, Gan J, Mosesson Y et al. Hsp90 restrains ErbB-2/HER2 signalling by limiting heterodimer formation. EMBO Rep. 5(12), 1165-1170(2004).
-
(2004)
EMBO Rep
-
-
Citri, A.1
Gan, J.2
Mosesson, Y.3
-
58
-
-
33744931946
-
Hsp90 recognizes a common surface on client kinases
-
Citri A, Harari D, Shohat G et al. Hsp90 recognizes a common surface on client kinases. J. Biol. Chem. 281(20), 14361-14369 (2006).
-
(2006)
J. Biol. Chem
, vol.281
, Issue.20
, pp. 14361-14369
-
-
Citri, A.1
Harari, D.2
Shohat, G.3
-
59
-
-
33847638137
-
Estimates of the cancer incidence and mortality in Europe in 2006
-
Ferlay J, Autier P, Boniol M et al. Estimates of the cancer incidence and mortality in Europe in 2006. Ann. Oncol. 18(3), 581-592 (2007).
-
(2007)
Ann. Oncol
, vol.18
, Issue.3
, pp. 581-592
-
-
Ferlay, J.1
Autier, P.2
Boniol, M.3
-
60
-
-
46949097619
-
-
Tumours of the breast. In: World Health Organization Classification of Tumours -Pathology and Genetics of Tumours of the Breast and Female Genital Organs. Tavassoli FA, Devilee P (Eds). IARC Press, Lyon, France (2003).
-
Tumours of the breast. In: World Health Organization Classification of Tumours -Pathology and Genetics of Tumours of the Breast and Female Genital Organs. Tavassoli FA, Devilee P (Eds). IARC Press, Lyon, France (2003).
-
-
-
-
61
-
-
37249004281
-
Predictive markers in breast cancer - the present
-
Payne SJ, Bowen RL, Jones JL, Wells CA. Predictive markers in breast cancer - the present. Histopathology 52(1), 82-90 (2008).
-
(2008)
Histopathology
, vol.52
, Issue.1
, pp. 82-90
-
-
Payne, S.J.1
Bowen, R.L.2
Jones, J.L.3
Wells, C.A.4
-
62
-
-
34548536058
-
Prognostic and predictive value of centrally reviewed expression of estrogen and progesterone receptors in a randomized trial comparing letrozole and tamoxifen adjuvant therapy for postmenopausal early breast cancer: BIG 1-98
-
Viale G, Regan MM, Maiorano E et al. Prognostic and predictive value of centrally reviewed expression of estrogen and progesterone receptors in a randomized trial comparing letrozole and tamoxifen adjuvant therapy for postmenopausal early breast cancer: BIG 1-98. J. Clin. Oncol. 25(25), 3846-3852 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.25
, pp. 3846-3852
-
-
Viale, G.1
Regan, M.M.2
Maiorano, E.3
-
63
-
-
0034680102
-
Molecular portraits of human breast tumours
-
Perou CM, Sorlie T, Eisen MB et al. Molecular portraits of human breast tumours. Nature 406(6797), 747-752 (2000).
-
(2000)
Nature
, vol.406
, Issue.6797
, pp. 747-752
-
-
Perou, C.M.1
Sorlie, T.2
Eisen, M.B.3
-
64
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sorlie T, Perou CM, Tibshirani R et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc. Natl Acad. Sci. USA 98(19), 10869-10874(2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, Issue.19
, pp. 10869-10874
-
-
Sorlie, T.1
Perou, C.M.2
Tibshirani, R.3
-
65
-
-
0037137519
-
A gene-expression signature as a predictor of survival in breast cancer
-
van de Vijver MJ, He YD, van't Veer LJ et al. A gene-expression signature as a predictor of survival in breast cancer. N. Engl. J. Med. 347(25), 1999-2009 (2002).
-
(2002)
N. Engl. J. Med
, vol.347
, Issue.25
, pp. 1999-2009
-
-
van de Vijver, M.J.1
He, Y.D.2
van't Veer, L.J.3
-
66
-
-
34247145491
-
Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade
-
Loi S, Haibe-Kains B, Desmedt C et al. Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade. J. Clin. Oncol. 25(10), 1239-1246 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.10
, pp. 1239-1246
-
-
Loi, S.1
Haibe-Kains, B.2
Desmedt, C.3
-
67
-
-
33645820586
-
Estrogen-regulated genes predict survival in hormone receptor-positive breast cancers
-
Oh DS, Troester MA, Usary J et al. Estrogen-regulated genes predict survival in hormone receptor-positive breast cancers. J. Clin. Oncol. 24(11), 1656-1664 (2006).
-
(2006)
J. Clin. Oncol
, vol.24
, Issue.11
, pp. 1656-1664
-
-
Oh, D.S.1
Troester, M.A.2
Usary, J.3
-
68
-
-
35048864555
-
Molecular classification system identifies invasive breast carcinoma patients who are most likely and those who are least likely to achieve a complete pathologic response after neoadjuvant chemotherapy
-
Goldstein NS, Decker D, Severson D et al. Molecular classification system identifies invasive breast carcinoma patients who are most likely and those who are least likely to achieve a complete pathologic response after neoadjuvant chemotherapy. Cancer 110(8), 1687-1696(2007).
-
(2007)
Cancer
, vol.110
, Issue.8
, pp. 1687-1696
-
-
Goldstein, N.S.1
Decker, D.2
Severson, D.3
-
69
-
-
27644567107
-
p63, cytokeratin 5, and P-cadherin: Three molecular markers to distinguish basal phenotype in breast carcinomas
-
Matos I, Dufloth R, Alvarenga M, Zeferino LC, Schmitt F. p63, cytokeratin 5, and P-cadherin: three molecular markers to distinguish basal phenotype in breast carcinomas. Virchows Arch. 447(4), 688-694 (2005).
-
(2005)
Virchows Arch
, vol.447
, Issue.4
, pp. 688-694
-
-
Matos, I.1
Dufloth, R.2
Alvarenga, M.3
Zeferino, L.C.4
Schmitt, F.5
-
70
-
-
84925550146
-
Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: Immunohistochemical and chromogenic in situ hybridization analysis
-
Reis-Filho JS, Milanezi F, Carvalho S et al. Metaplastic breast carcinomas exhibit EGFR, but not HER2, gene amplification and overexpression: immunohistochemical and chromogenic in situ hybridization analysis. Breast Cancer Res. 7(6), R1028-R1035 (2005).
-
(2005)
Breast Cancer Res
, vol.7
, Issue.6
-
-
Reis-Filho, J.S.1
Milanezi, F.2
Carvalho, S.3
-
71
-
-
20144387584
-
Phenotypic characterization of BRCA1 and BRCA2 tumors based in a tissue microarray study with 37 immunohistochemical markers
-
Palacios J, Honrado E, Osorio A et al. Phenotypic characterization of BRCA1 and BRCA2 tumors based in a tissue microarray study with 37 immunohistochemical markers. Breast Cancer Res. Treat. 90(1), 5-14 (2005).
-
(2005)
Breast Cancer Res. Treat
, vol.90
, Issue.1
, pp. 5-14
-
-
Palacios, J.1
Honrado, E.2
Osorio, A.3
-
72
-
-
0036997114
-
Aberrant P-cadherin expression: Is it associated with estrogen-independent growth in breast cancer?
-
Paredes J, Milanezi F, Reis-Filho JS et al. Aberrant P-cadherin expression: is it associated with estrogen-independent growth in breast cancer? Pathol. Res. Pract. 198(12), 795-801 (2002).
-
(2002)
Pathol. Res. Pract
, vol.198
, Issue.12
, pp. 795-801
-
-
Paredes, J.1
Milanezi, F.2
Reis-Filho, J.S.3
-
73
-
-
0037347755
-
Novel and classic myoepithelial/stem cell markers in metaplastic carcinomas of the breast
-
Reis-Filho JS, Milanezi F, Paredes J et al. Novel and classic myoepithelial/stem cell markers in metaplastic carcinomas of the breast. Appl. Immunohistochem. Mol. Morphol. 11(1), 1-8 (2003).
-
(2003)
Appl. Immunohistochem. Mol. Morphol
, vol.11
, Issue.1
, pp. 1-8
-
-
Reis-Filho, J.S.1
Milanezi, F.2
Paredes, J.3
-
74
-
-
33746911642
-
EGFR amplification and lack of activating mutations in metaplastic breast carcinomas
-
Reis-Filho J, Pinheiro C, Lambros M et al. EGFR amplification and lack of activating mutations in metaplastic breast carcinomas. J. Pathol. 209, 445-453 (2006).
-
(2006)
J. Pathol
, vol.209
, pp. 445-453
-
-
Reis-Filho, J.1
Pinheiro, C.2
Lambros, M.3
-
75
-
-
33745653114
-
Metaplastic breast carcinomas are basal-like tumours
-
Reis-Filho JS, Milanezi F, Steele D et al. Metaplastic breast carcinomas are basal-like tumours. Histopathology 49(1), 10-21 (2006).
-
(2006)
Histopathology
, vol.49
, Issue.1
, pp. 10-21
-
-
Reis-Filho, J.S.1
Milanezi, F.2
Steele, D.3
-
76
-
-
33847292843
-
Breast carcinoma with basal differentiation: A proposal for pathology definition based on basal cytokeratin expression
-
Rakha EA, El-Sayed ME, Green AR et al. Breast carcinoma with basal differentiation: a proposal for pathology definition based on basal cytokeratin expression. Histopathology 50(4), 434-438 (2007).
-
(2007)
Histopathology
, vol.50
, Issue.4
, pp. 434-438
-
-
Rakha, E.A.1
El-Sayed, M.E.2
Green, A.R.3
-
77
-
-
37248999372
-
Triple negative tumours: A critical review
-
Reis-Filho JS, Tutt AN. Triple negative tumours: a critical review. Histopathology 52(1), 108-118 (2008).
-
(2008)
Histopathology
, vol.52
, Issue.1
, pp. 108-118
-
-
Reis-Filho, J.S.1
Tutt, A.N.2
-
78
-
-
30944450821
-
Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma
-
Livasy CA, Karaca G, Nanda R et al. Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma. Mod. Pathol. 19(2), 264-271 (2006).
-
(2006)
Mod. Pathol
, vol.19
, Issue.2
, pp. 264-271
-
-
Livasy, C.A.1
Karaca, G.2
Nanda, R.3
-
80
-
-
33845215486
-
Basal phenotype identifies a poor prognostic subgroup of breast cancer of clinical importance
-
Rakha EA, El-Rehim DA, Paish C et al. Basal phenotype identifies a poor prognostic subgroup of breast cancer of clinical importance. Eur. J. Cancer 42(18), 3149-3156 (2006).
-
(2006)
Eur. J. Cancer
, vol.42
, Issue.18
, pp. 3149-3156
-
-
Rakha, E.A.1
El-Rehim, D.A.2
Paish, C.3
-
81
-
-
38149124802
-
The influence of basal phenotype on the metastatic pattern of breast cancer
-
Luck AA, Evans AJ, Green AR et al. The influence of basal phenotype on the metastatic pattern of breast cancer. Clin. Oncol. (R. Coll. Radiol.) 20(1), 40-45 (2008).
-
(2008)
Clin. Oncol. (R. Coll. Radiol.)
, vol.20
, Issue.1
, pp. 40-45
-
-
Luck, A.A.1
Evans, A.J.2
Green, A.R.3
-
82
-
-
33744750480
-
Basal-like breast carcinomas: Clinical outcome and response to chemotherapy
-
Banerjee S, Reis-Filho JS, Ashley S et al. Basal-like breast carcinomas: clinical outcome and response to chemotherapy. J. Clin. Pathol. 59(7), 729-735 (2006).
-
(2006)
J. Clin. Pathol
, vol.59
, Issue.7
, pp. 729-735
-
-
Banerjee, S.1
Reis-Filho, J.S.2
Ashley, S.3
-
83
-
-
37448999035
-
Triple negative breast cancer: Molecular profiling and prognostic impact in adjuvant anthracycline-treated patients
-
Epub ahead of print
-
Tan DS, Marchio C, Jones RL et al. Triple negative breast cancer: molecular profiling and prognostic impact in adjuvant anthracycline-treated patients. Breast Cancer Res. Treat. (2007) (Epub ahead of print).
-
(2007)
Breast Cancer Res. Treat
-
-
Tan, D.S.1
Marchio, C.2
Jones, R.L.3
-
84
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu oncogene
-
Slamon DJ, Clark GM, Wong SG et al. Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene. Science 235(4785), 177-182 (1987).
-
(1987)
Science
, vol.235
, Issue.4785
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
-
85
-
-
38149032775
-
Basal-HER2 phenotype shows poorer survival than basal-like phenotype in hormone receptor-negative invasive breast cancers
-
Liu H, Fan Q, Zhang Z et al. Basal-HER2 phenotype shows poorer survival than basal-like phenotype in hormone receptor-negative invasive breast cancers. Hum. Pathol. 39(2), 167-174 (2008).
-
(2008)
Hum. Pathol
, vol.39
, Issue.2
, pp. 167-174
-
-
Liu, H.1
Fan, Q.2
Zhang, Z.3
-
86
-
-
33947246109
-
Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer
-
Harris LN, You F, Schnitt SJ et al. Predictors of resistance to preoperative trastuzumab and vinorelbine for HER2-positive early breast cancer. Clin. Cancer Res. 13(4), 1198-1207 (2007).
-
(2007)
Clin. Cancer Res
, vol.13
, Issue.4
, pp. 1198-1207
-
-
Harris, L.N.1
You, F.2
Schnitt, S.J.3
-
87
-
-
34247363714
-
Standardization of HER2 testing: Results of an international proficiency-testing ring study
-
Dowsett M, Hanna WM, Kockx M et al. Standardization of HER2 testing: results of an international proficiency-testing ring study. Mod. Pathol. 20(5), 584-591 (2007).
-
(2007)
Mod. Pathol
, vol.20
, Issue.5
, pp. 584-591
-
-
Dowsett, M.1
Hanna, W.M.2
Kockx, M.3
-
88
-
-
36849069347
-
American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer
-
Harris L, Fritsche H, Mennel R et al. American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer. J. Clin. Oncol. 25(33), 5287-5312 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.33
, pp. 5287-5312
-
-
Harris, L.1
Fritsche, H.2
Mennel, R.3
-
89
-
-
38049103907
-
HER2 status and efficacy of adjuvant anthracyclines in early breast cancer: A pooled analysis of randomized trials
-
Gennari A, Sormani MP, Pronzato P et al. HER2 status and efficacy of adjuvant anthracyclines in early breast cancer: a pooled analysis of randomized trials. J. Natl Cancer Inst. 100(1), 14-20 (2008).
-
(2008)
J. Natl Cancer Inst
, vol.100
, Issue.1
, pp. 14-20
-
-
Gennari, A.1
Sormani, M.P.2
Pronzato, P.3
-
90
-
-
32944475493
-
Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish Breast Cancer Cooperative Group
-
Knoop AS, Knudsen H, Balslev E et al. Retrospective analysis of topoisomerase IIa amplifications and deletions as predictive markers in primary breast cancer patients randomly assigned to cyclophosphamide, methotrexate, and fluorouracil or cyclophosphamide, epirubicin, and fluorouracil: Danish Breast Cancer Cooperative Group. J. Clin. Oncol. 23(30), 7483-7490 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.30
, pp. 7483-7490
-
-
Knoop, A.S.1
Knudsen, H.2
Balslev, E.3
-
91
-
-
0036091354
-
HER-2 amplification and topoisomerase IIα gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil
-
Di Leo A, Gancberg D, Larsimont D et al. HER-2 amplification and topoisomerase IIα gene aberrations as predictive markers in node-positive breast cancer patients randomly treated either with an anthracycline-based therapy or with cyclophosphamide, methotrexate, and 5-fluorouracil. Clin. Cancer Res. 8(5), 1107-1116 (2002).
-
(2002)
Clin. Cancer Res
, vol.8
, Issue.5
, pp. 1107-1116
-
-
Di Leo, A.1
Gancberg, D.2
Larsimont, D.3
-
92
-
-
0033870292
-
Amplification and deletion of topoisomerase IIα associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer
-
Jarvinen TA, Tanner M, Rantanen V et al. Amplification and deletion of topoisomerase IIα associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer. Am. J. Pathol. 156(3), 839-847 (2000).
-
(2000)
Am. J. Pathol
, vol.156
, Issue.3
, pp. 839-847
-
-
Jarvinen, T.A.1
Tanner, M.2
Rantanen, V.3
-
93
-
-
0035884620
-
Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: Evidence from a Phase III randomized trial
-
Ellis MJ, Coop A, Singh B et al. Letrozole is more effective neoadjuvant endocrine therapy than tamoxifen for ErbB-1- and/or ErbB-2-positive, estrogen receptor-positive primary breast cancer: evidence from a Phase III randomized trial. J. Clin. Oncol. 19(18), 3808-3816 (2001).
-
(2001)
J. Clin. Oncol
, vol.19
, Issue.18
, pp. 3808-3816
-
-
Ellis, M.J.1
Coop, A.2
Singh, B.3
-
94
-
-
37449028688
-
-
Arimidex T, Alone or in Combination (ATAC) Trialists' Group, Forbes JF et al. Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial. Lancet Oncol. 9(1), 45-53 (2008).
-
Arimidex T, Alone or in Combination (ATAC) Trialists' Group, Forbes JF et al. Effect of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: 100-month analysis of the ATAC trial. Lancet Oncol. 9(1), 45-53 (2008).
-
-
-
-
95
-
-
20244374413
-
Biomarker changes during neoadjuvant anastrozole, tamoxifen, or the combination: Influence of hormonal status and HER-2 in breast cancer - a study from the IMPACT trialists
-
Dowsett M, Ebbs SR, Dixon JM et al. Biomarker changes during neoadjuvant anastrozole, tamoxifen, or the combination: influence of hormonal status and HER-2 in breast cancer - a study from the IMPACT trialists. J. Clin. Oncol. 23(11), 2477-2492 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.11
, pp. 2477-2492
-
-
Dowsett, M.1
Ebbs, S.R.2
Dixon, J.M.3
-
96
-
-
37549056583
-
Adjuvant letrozole versus tamoxifen according to centrally-assessed ERBB2 status for postmenopausal women with endocrine-responsive early breast cancer: Supplementary results from the BIG 1-98 randomised trial
-
Rasmussen BB, Regan MM, Lykkesfeldt AE et al. Adjuvant letrozole versus tamoxifen according to centrally-assessed ERBB2 status for postmenopausal women with endocrine-responsive early breast cancer: supplementary results from the BIG 1-98 randomised trial. Lancet Oncol. 9(1), 23-28 (2008).
-
(2008)
Lancet Oncol
, vol.9
, Issue.1
, pp. 23-28
-
-
Rasmussen, B.B.1
Regan, M.M.2
Lykkesfeldt, A.E.3
-
97
-
-
0036187710
-
NH(2)-terminal truncated HER-2 protein but not full-length receptor is associated with nodal metastasis in human breast cancer
-
Molina MA, Saez R, Ramsey EE et al. NH(2)-terminal truncated HER-2 protein but not full-length receptor is associated with nodal metastasis in human breast cancer. Clin. Cancer Res. 8(2), 347-353 (2002).
-
(2002)
Clin. Cancer Res
, vol.8
, Issue.2
, pp. 347-353
-
-
Molina, M.A.1
Saez, R.2
Ramsey, E.E.3
-
98
-
-
0026071364
-
The extracellular domain of pl85/neu is released from the surface of human breast carcinoma cells, SK-BR-3
-
Zabrecky JR, Lam T, McKenzie SJ, Carney W. The extracellular domain of pl85/neu is released from the surface of human breast carcinoma cells, SK-BR-3. J. Biol. Chem. 266(3), 1716-1720 (1991).
-
(1991)
J. Biol. Chem
, vol.266
, Issue.3
, pp. 1716-1720
-
-
Zabrecky, J.R.1
Lam, T.2
McKenzie, S.J.3
Carney, W.4
-
99
-
-
14644401104
-
Serum HER2 extracellular domain in metastatic breast cancer patients treated with weekly trastuzumab and paclitaxel: Association with HER2 status by immunohistochemistry and fluorescence in situ hybridization and with response rate
-
Fornier MN, Seidman AD, Schwartz MK et al. Serum HER2 extracellular domain in metastatic breast cancer patients treated with weekly trastuzumab and paclitaxel: association with HER2 status by immunohistochemistry and fluorescence in situ hybridization and with response rate. Ann. Oncol. 16(2), 234-239 (2005).
-
(2005)
Ann. Oncol
, vol.16
, Issue.2
, pp. 234-239
-
-
Fornier, M.N.1
Seidman, A.D.2
Schwartz, M.K.3
-
100
-
-
2442591882
-
-
Serum levels of HER2 ECD can determine the response rate to low dose oral cyclophosphamide and methotrexate in patients with advanced stage breast carcinoma, 242C, 1261-1266
-
Sandri MT, Johansson H, Colleoni M et al. Serum levels of HER2 ECD can determine the response rate to low dose oral cyclophosphamide and methotrexate in patients with advanced stage breast carcinoma. Anticancer Res. 24(2C), 1261-1266 (2004).
-
(2004)
Anticancer Res
-
-
Sandri, M.T.1
Johansson, H.2
Colleoni, M.3
-
101
-
-
33646157497
-
Ductal carcinoma in situ with basal-like phenotype: A possible precursor to invasive basal-like breast cancer
-
Bryan BB, Schnitt SJ, Collins LC. Ductal carcinoma in situ with basal-like phenotype: a possible precursor to invasive basal-like breast cancer. Mod. Pathol. 19(5), 617-621 (2006).
-
(2006)
Mod. Pathol
, vol.19
, Issue.5
, pp. 617-621
-
-
Bryan, B.B.1
Schnitt, S.J.2
Collins, L.C.3
-
102
-
-
33847663351
-
P-cadherin and cytokeratin 5: Useful adjunct markers to distinguish basal-like ductal carcinomas in situ
-
Paredes J, Lopes N, Milanezi F, Schmitt FC. P-cadherin and cytokeratin 5: useful adjunct markers to distinguish basal-like ductal carcinomas in situ. Virchows Arch. 450(1), 73-80 (2007).
-
(2007)
Virchows Arch
, vol.450
, Issue.1
, pp. 73-80
-
-
Paredes, J.1
Lopes, N.2
Milanezi, F.3
Schmitt, F.C.4
-
103
-
-
33846197980
-
Identification of a basal-like subtype of breast ductal carcinoma in situ
-
Livasy CA, Perou CM, Karaca G et al. Identification of a basal-like subtype of breast ductal carcinoma in situ. Hum. Pathol. 38(2), 197-204 (2007).
-
(2007)
Hum. Pathol
, vol.38
, Issue.2
, pp. 197-204
-
-
Livasy, C.A.1
Perou, C.M.2
Karaca, G.3
-
104
-
-
33847339743
-
A mouse model of basal-like breast carcinoma with metaplastic elements
-
McCarthy A, Savage K, Gabriel A et al. A mouse model of basal-like breast carcinoma with metaplastic elements. J. Pathol. 211 (4), 389-398 (2007).
-
(2007)
J. Pathol
, vol.211
, Issue.4
, pp. 389-398
-
-
McCarthy, A.1
Savage, K.2
Gabriel, A.3
-
105
-
-
33646428682
-
The basal phenotype of BRCAl-related breast cancer: Past, present and future
-
Tischkowitz MD, Foulkes WD. The basal phenotype of BRCAl-related breast cancer: past, present and future. Cell Cycle 5(9), 963-967 (2006).
-
(2006)
Cell Cycle
, vol.5
, Issue.9
, pp. 963-967
-
-
Tischkowitz, M.D.1
Foulkes, W.D.2
-
106
-
-
33847035558
-
-
James CR, Quinn JE, Mullan PB, Johnston Harkin DP. BRCAl, a potential predictive biomarker in the treatment of breast cancer. Oncologist 12(2), 142-150(2007).
-
James CR, Quinn JE, Mullan PB, Johnston PG, Harkin DP. BRCAl, a potential predictive biomarker in the treatment of breast cancer. Oncologist 12(2), 142-150(2007).
-
-
-
-
107
-
-
0026571910
-
The clinical significance of epidermal growth factor receptor (EGF-R) in human breast cancer: A review on 5232 patients
-
Klijn JG, Berns PM, Schmitz PI, Foekens JA. The clinical significance of epidermal growth factor receptor (EGF-R) in human breast cancer: a review on 5232 patients. Endocr. Rev. 13(1), 3-17 (1992).
-
(1992)
Endocr. Rev
, vol.13
, Issue.1
, pp. 3-17
-
-
Klijn, J.G.1
Berns, P.M.2
Schmitz, P.I.3
Foekens, J.A.4
-
108
-
-
24044520039
-
EGFR gene amplification in breast cancer: Correlation with epidermal growth factor receptor mRNA and protein expression and HER-2 status and absence of EGFR-activating mutations
-
Bhargava R, Gerald WL, Li AR et al. EGFR gene amplification in breast cancer: correlation with epidermal growth factor receptor mRNA and protein expression and HER-2 status and absence of EGFR-activating mutations. Mod. Pathol. 18(8), 1027-1033(2005).
-
(2005)
Mod. Pathol
, vol.18
, Issue.8
, pp. 1027-1033
-
-
Bhargava, R.1
Gerald, W.L.2
Li, A.R.3
-
109
-
-
38849208351
-
Independent prognostic value of the basal-like phenotype of breast cancer and associations with EGFR and candidate stem cell marker BMI-1
-
Arnes JB, Collett K, Akslen LA. Independent prognostic value of the basal-like phenotype of breast cancer and associations with EGFR and candidate stem cell marker BMI-1. Histopathology 52(3), 370-380 (2008).
-
(2008)
Histopathology
, vol.52
, Issue.3
, pp. 370-380
-
-
Arnes, J.B.1
Collett, K.2
Akslen, L.A.3
-
110
-
-
23444460828
-
Epidermal growth factor receptor expression correlates with poor survival in patients who have breast carcinoma treated with doxorubicin-based neoadjuvant chemotherapy
-
Buchholz TA, Tu X, Ang KK et al. Epidermal growth factor receptor expression correlates with poor survival in patients who have breast carcinoma treated with doxorubicin-based neoadjuvant chemotherapy. Cancer 104(4), 676-681 (2005).
-
(2005)
Cancer
, vol.104
, Issue.4
, pp. 676-681
-
-
Buchholz, T.A.1
Tu, X.2
Ang, K.K.3
-
111
-
-
40949121882
-
Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype
-
Cheang MC, Voduc D, Bajdik C et al. Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype. Clin. Cancer Res. 14(5), 1368-1376 (2008).
-
(2008)
Clin. Cancer Res
, vol.14
, Issue.5
, pp. 1368-1376
-
-
Cheang, M.C.1
Voduc, D.2
Bajdik, C.3
-
112
-
-
24644445676
-
Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients
-
Cappuzzo F, Varella-Garcia M, Shigematsu H et al. Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients. J. Clin. Oncol. 23(22), 5007-5018 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.22
, pp. 5007-5018
-
-
Cappuzzo, F.1
Varella-Garcia, M.2
Shigematsu, H.3
-
113
-
-
20444498630
-
Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer
-
Cappuzzo F, Hirsch FR, Rossi E et al. Epidermal growth factor receptor gene and protein and gefitinib sensitivity in non-small-cell lung cancer. J. Natl Cancer Inst. 97(9), 643-655 (2005).
-
(2005)
J. Natl Cancer Inst
, vol.97
, Issue.9
, pp. 643-655
-
-
Cappuzzo, F.1
Hirsch, F.R.2
Rossi, E.3
-
114
-
-
0142119289
-
Epidermal growth factor receptor in non-small-cell lung carcinomas: Correlation between gene copy number and protein expression and impact on prognosis
-
Hirsch FR, Varella-Garcia M, Bunn PA Jr et al. Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis. J. Clin. Oncol. 21(20), 3798-3807 (2003).
-
(2003)
J. Clin. Oncol
, vol.21
, Issue.20
, pp. 3798-3807
-
-
Hirsch, F.R.1
Varella-Garcia, M.2
Bunn Jr, P.A.3
-
115
-
-
36649030622
-
Expression and amplification of Her2, EGFR and cyclin Dl in breast cancer: Immunohistochemistry and chromogenic in situ hybridization
-
Cho EY, Choi YL, Han JJ, Kim KM, Oh YL. Expression and amplification of Her2, EGFR and cyclin Dl in breast cancer: immunohistochemistry and chromogenic in situ hybridization. Pathol. Int. 58(1), 17-25 (2008).
-
(2008)
Pathol. Int
, vol.58
, Issue.1
, pp. 17-25
-
-
Cho, E.Y.1
Choi, Y.L.2
Han, J.J.3
Kim, K.M.4
Oh, Y.L.5
-
116
-
-
44149098849
-
Cytogenetic analysis of HER1/EGFR, HER2, HER3 and HER4 in 278 breast cancer patients
-
Sassen A, Rochon J, Wild P et al. Cytogenetic analysis of HER1/EGFR, HER2, HER3 and HER4 in 278 breast cancer patients. Breast Cancer Res. 10(1), R2 (2008).
-
(2008)
Breast Cancer Res
, vol.10
, Issue.1
-
-
Sassen, A.1
Rochon, J.2
Wild, P.3
-
117
-
-
33847323129
-
Epidermal growth factor receptor mutations in lung cancer
-
Sharma SV, Bell DW, Settleman J, Haber DA. Epidermal growth factor receptor mutations in lung cancer. Nat. Rev. Cancer 7(3), 169-181 (2007).
-
(2007)
Nat. Rev. Cancer
, vol.7
, Issue.3
, pp. 169-181
-
-
Sharma, S.V.1
Bell, D.W.2
Settleman, J.3
Haber, D.A.4
-
119
-
-
33745986327
-
HER2 testing by local, central, and reference laboratories in specimens from the North Central Cancer Treatment Group N9831 intergroup adjuvant trial
-
Perez EA, Suman VJ, Davidson NE et al. HER2 testing by local, central, and reference laboratories in specimens from the North Central Cancer Treatment Group N9831 intergroup adjuvant trial. J. Clin. Oncol. 24(19), 3032-3038 (2006).
-
(2006)
J. Clin. Oncol
, vol.24
, Issue.19
, pp. 3032-3038
-
-
Perez, E.A.1
Suman, V.J.2
Davidson, N.E.3
-
120
-
-
34447302567
-
External quality assurance of HER2 fluorescence in situ hybridisation testing: Results of a UK NEQAS pilot scheme
-
Bartlett JM, Ibrahim M, Jasani B et al. External quality assurance of HER2 fluorescence in situ hybridisation testing: results of a UK NEQAS pilot scheme. J. Clin. Pathol. 60(7), 816-819 (2007).
-
(2007)
J. Clin. Pathol
, vol.60
, Issue.7
, pp. 816-819
-
-
Bartlett, J.M.1
Ibrahim, M.2
Jasani, B.3
-
121
-
-
1542503725
-
HER-2 testing and trastuzumab therapy for metastatic breast cancer: A cost-effectiveness analysis
-
Elkin EB, Weinstein MC, Winer EP et al. HER-2 testing and trastuzumab therapy for metastatic breast cancer: a cost-effectiveness analysis. J. Clin. Oncol. 22(5), 854-863 (2004).
-
(2004)
J. Clin. Oncol
, vol.22
, Issue.5
, pp. 854-863
-
-
Elkin, E.B.1
Weinstein, M.C.2
Winer, E.P.3
-
122
-
-
36849043530
-
Quantitative justification of the change from 10% to 30% for human epidermal growth factor receptor 2 scoring in the American Society of Clinical Oncology/College of American Pathologists guidelines: Tumor heterogeneity in breast cancer and its implications for tissue microarray based assessment of outcome
-
Moeder CB, Giltnane JM, Harigopal M et al. Quantitative justification of the change from 10% to 30% for human epidermal growth factor receptor 2 scoring in the American Society of Clinical Oncology/College of American Pathologists guidelines: tumor heterogeneity in breast cancer and its implications for tissue microarray based assessment of outcome. J. Clin. Oncol. 25(34), 5418-5425 (2007).
-
(2007)
J. Clin. Oncol
, vol.25
, Issue.34
, pp. 5418-5425
-
-
Moeder, C.B.1
Giltnane, J.M.2
Harigopal, M.3
-
123
-
-
0347539778
-
Calibration of immunohistochemistry for assessment of HER2 in breast cancer: Results of the French multicentre GEFPICS study
-
Vincent-Salomon A, MacGrogan G, Couturier J et al. Calibration of immunohistochemistry for assessment of HER2 in breast cancer: results of the French multicentre GEFPICS study. Histopathology 42(4), 337-347 (2003).
-
(2003)
Histopathology
, vol.42
, Issue.4
, pp. 337-347
-
-
Vincent-Salomon, A.1
MacGrogan, G.2
Couturier, J.3
-
124
-
-
26844498595
-
Phosphorylated/activated HER2 as a marker of clinical resistance to single agent taxane chemotherapy for metastatic breast cancer
-
Modi S, DiGiovanna MP, Lu Z et al. Phosphorylated/activated HER2 as a marker of clinical resistance to single agent taxane chemotherapy for metastatic breast cancer. Cancer Invest. 23(6), 483-487 (2005).
-
(2005)
Cancer Invest
, vol.23
, Issue.6
, pp. 483-487
-
-
Modi, S.1
DiGiovanna, M.P.2
Lu, Z.3
-
125
-
-
34548843012
-
HER2 evaluation using the novel rabbit monoclonal antibody SP3 and CISH in tissue microarrays of invasive breast carcinomas
-
Ricardo SA, Milanezi F, Carvalho ST, Leitao DR, Schmitt FC. HER2 evaluation using the novel rabbit monoclonal antibody SP3 and CISH in tissue microarrays of invasive breast carcinomas. J. Clin. Pathol. 60(9), 1001-1005 (2007).
-
(2007)
J. Clin. Pathol
, vol.60
, Issue.9
, pp. 1001-1005
-
-
Ricardo, S.A.1
Milanezi, F.2
Carvalho, S.T.3
Leitao, D.R.4
Schmitt, F.C.5
-
126
-
-
18044392064
-
A modified trastuzumab antibody for the immunohistochemical detection of HER-2 overexpression in breast cancer
-
Bussolati G, Montemurro F, Righi L et al. A modified trastuzumab antibody for the immunohistochemical detection of HER-2 overexpression in breast cancer. Br. J. Cancer 92(7), 1261-1267 (2005).
-
(2005)
Br. J. Cancer
, vol.92
, Issue.7
, pp. 1261-1267
-
-
Bussolati, G.1
Montemurro, F.2
Righi, L.3
-
127
-
-
37349046484
-
Patients with advanced stage breast carcinoma immunoreactive to biotinylated Herceptin are most likely to benefit from trastuzumab-based therapy: An hypothesis-generating study
-
Sapino A, Montemurro F, Marchio C et al. Patients with advanced stage breast carcinoma immunoreactive to biotinylated Herceptin are most likely to benefit from trastuzumab-based therapy: an hypothesis-generating study. Ann. Oncol. 18(12), 1963-1968 (2007).
-
(2007)
Ann. Oncol
, vol.18
, Issue.12
, pp. 1963-1968
-
-
Sapino, A.1
Montemurro, F.2
Marchio, C.3
-
128
-
-
0035874981
-
Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells
-
Molina MA, Codony-Servat J, Albanell J et al. Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells. Cancer Res. 61(12), 4744-4749 (2001).
-
(2001)
Cancer Res
, vol.61
, Issue.12
, pp. 4744-4749
-
-
Molina, M.A.1
Codony-Servat, J.2
Albanell, J.3
-
129
-
-
33745765680
-
Identification of ADAM 10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells
-
Liu PC, Liu X, Li Y et al. Identification of ADAM 10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells. Cancer Biol. Ther. 5(6), 657-664 (2006).
-
(2006)
Cancer Biol. Ther
, vol.5
, Issue.6
, pp. 657-664
-
-
Liu, P.C.1
Liu, X.2
Li, Y.3
-
130
-
-
33644528230
-
Clinical utility of serum HER2/neu in monitoring and prediction of progression-free survival in metastatic breast cancer patients treated with trastuzumab-based therapies
-
Esteva FJ, Cheli CD, Fritsche H et al. Clinical utility of serum HER2/neu in monitoring and prediction of progression-free survival in metastatic breast cancer patients treated with trastuzumab-based therapies. Breast Cancer Res. 7(4), R436-R443 (2005).
-
(2005)
Breast Cancer Res
, vol.7
, Issue.4
-
-
Esteva, F.J.1
Cheli, C.D.2
Fritsche, H.3
-
131
-
-
33745877913
-
Concordance between central and local laboratory HER2 testing from a community-based clinical study
-
Reddy JC, Reimann JD, Anderson SM, Klein PM. Concordance between central and local laboratory HER2 testing from a community-based clinical study. Clin. Breast Cancer 7(2), 153-157 (2006).
-
(2006)
Clin. Breast Cancer
, vol.7
, Issue.2
, pp. 153-157
-
-
Reddy, J.C.1
Reimann, J.D.2
Anderson, S.M.3
Klein, P.M.4
-
132
-
-
38049055410
-
HER2 testing in a population-based study of patients with metastatic breast cancer treated with trastuzumab
-
O'Malley FP, Thomson T, Julian J et al. HER2 testing in a population-based study of patients with metastatic breast cancer treated with trastuzumab. Arch. Pathol. lab. Med. 132(1), 61-65 (2008).
-
(2008)
Arch. Pathol. lab. Med
, vol.132
, Issue.1
, pp. 61-65
-
-
O'Malley, F.P.1
Thomson, T.2
Julian, J.3
-
133
-
-
33747622311
-
HER2 testing in breast cancer: NCCN Task Force report and recommendations
-
quiz S23-S24
-
Carlson RW, Moench SJ, Hammond ME et al. HER2 testing in breast cancer: NCCN Task Force report and recommendations. J. Natl Compr. Canc. Netw. 4(Suppl. 3), S1-S22; quiz S23-S24 (2006).
-
(2006)
J. Natl Compr. Canc. Netw
, vol.4
, Issue.SUPPL. 3
-
-
Carlson, R.W.1
Moench, S.J.2
Hammond, M.E.3
-
134
-
-
36649015630
-
Fluorescence in situ hybridization (FISH) as primary methodology for the assessment of HER2 status in adenocarcinoma of the breast: A single institution experience
-
Tubbs RR, Hicks DG, Cook J et al. Fluorescence in situ hybridization (FISH) as primary methodology for the assessment of HER2 status in adenocarcinoma of the breast: a single institution experience. Diagn. Mol Pathol. 16(4), 207-210 (2007).
-
(2007)
Diagn. Mol Pathol
, vol.16
, Issue.4
, pp. 207-210
-
-
Tubbs, R.R.1
Hicks, D.G.2
Cook, J.3
-
135
-
-
20444457037
-
Polysomy 17 in HER-2/neu status elaboration in breast cancer: Effect on daily practice
-
Ma Y, Lespagnard L, Durbecq V, Paesmans M et al. Polysomy 17 in HER-2/neu status elaboration in breast cancer: effect on daily practice. Clin. Cancer Res. 11(12), 4393-4399 (2005).
-
(2005)
Clin. Cancer Res
, vol.11
, Issue.12
, pp. 4393-4399
-
-
Ma, Y.1
Lespagnard, L.2
Durbecq, V.3
Paesmans, M.4
-
136
-
-
33745153139
-
Analysis of aneusomy level and HER-2 gene copy number and their effect on amplification rate in breast cancer specimens read as 2+ in immunohistochemical analysis
-
Merola R, Mottolese M, Orlandi G et al. Analysis of aneusomy level and HER-2 gene copy number and their effect on amplification rate in breast cancer specimens read as 2+ in immunohistochemical analysis. Eur. J. Cancer 42(10), 1501-1506 (2006).
-
(2006)
Eur. J. Cancer
, vol.42
, Issue.10
, pp. 1501-1506
-
-
Merola, R.1
Mottolese, M.2
Orlandi, G.3
-
137
-
-
33747883996
-
Dual-colour chromogenic in situ hybridization for testing of HER-2 oncogene amplification in archival breast tumours
-
Laakso M, Tanner M, Isola J. Dual-colour chromogenic in situ hybridization for testing of HER-2 oncogene amplification in archival breast tumours. J. Pathol. 210(1), 3-9 (2006).
-
(2006)
J. Pathol
, vol.210
, Issue.1
, pp. 3-9
-
-
Laakso, M.1
Tanner, M.2
Isola, J.3
-
138
-
-
28044458147
-
Role of chromogenic in situ hybridization (CISH) in the evaluation of HER2 status in breast carcinoma: Comparison with immunohistochemistry and FISH
-
Li-Ning TE, Ronchetti R, Torres-Cabala C, Merino MJ. Role of chromogenic in situ hybridization (CISH) in the evaluation of HER2 status in breast carcinoma: comparison with immunohistochemistry and FISH. Int. J. Surg. Pathol. 13(4), 343-351 (2005).
-
(2005)
Int. J. Surg. Pathol
, vol.13
, Issue.4
, pp. 343-351
-
-
Li-Ning, T.E.1
Ronchetti, R.2
Torres-Cabala, C.3
Merino, M.J.4
-
139
-
-
34447295638
-
Chromogenic and fluorescent in situ hybridization in breast cancer
-
Lambros MB, Natrajan R, Reis-Filho JS. Chromogenic and fluorescent in situ hybridization in breast cancer. Hum. Pathol. 38(8), 1105-1122(2007).
-
(2007)
Hum. Pathol
, vol.38
, Issue.8
, pp. 1105-1122
-
-
Lambros, M.B.1
Natrajan, R.2
Reis-Filho, J.S.3
-
140
-
-
35748985896
-
Comparison of automated silver enhanced in situ hybridisation (SISH) and fluorescence ISH (FISH) for the validation of HER2 gene status in breast carcinoma according to the guidelines of the American Society of Clinical Oncology and the College of American Pathologists
-
Dietel M, Ellis IO, Hofler H et al. Comparison of automated silver enhanced in situ hybridisation (SISH) and fluorescence ISH (FISH) for the validation of HER2 gene status in breast carcinoma according to the guidelines of the American Society of Clinical Oncology and the College of American Pathologists. Virchows Arch. 451(1), 19-25 (2007).
-
(2007)
Virchows Arch
, vol.451
, Issue.1
, pp. 19-25
-
-
Dietel, M.1
Ellis, I.O.2
Hofler, H.3
-
141
-
-
28444491796
-
Gefitinib (ZD1839) combined with weekly epirubicin in patients with metastatic breast cancer: A Phase I study with biological correlate
-
Gasparini G, Sarmiento R, Amici S et al. Gefitinib (ZD1839) combined with weekly epirubicin in patients with metastatic breast cancer: a Phase I study with biological correlate. Ann. Oncol. 16(12), 1867-1873 (2005).
-
(2005)
Ann. Oncol
, vol.16
, Issue.12
, pp. 1867-1873
-
-
Gasparini, G.1
Sarmiento, R.2
Amici, S.3
-
142
-
-
19944408390
-
Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogen-receptor positive and epidermal-growth-factor-receptor-positive primary breast cancer: A double-blind placebo-controlled Phase II randomised trial
-
Polychronis A, Sinnett HD, Hadjiminas D et al. Preoperative gefitinib versus gefitinib and anastrozole in postmenopausal patients with oestrogen-receptor positive and epidermal-growth-factor-receptor-positive primary breast cancer: a double-blind placebo-controlled Phase II randomised trial. Lancet Oncol. 6(6), 383-391 (2005).
-
(2005)
Lancet Oncol
, vol.6
, Issue.6
, pp. 383-391
-
-
Polychronis, A.1
Sinnett, H.D.2
Hadjiminas, D.3
-
143
-
-
20844456577
-
A multicentre Phase II study on gefitinib in taxane- and anthracycline-pretreated metastatic breast cancer
-
von Minckwitz G, Jonat W, Fasching P et al. A multicentre Phase II study on gefitinib in taxane- and anthracycline-pretreated metastatic breast cancer. Breast Cancer Res. Treat. 89(2), 165-172 (2005).
-
(2005)
Breast Cancer Res. Treat
, vol.89
, Issue.2
, pp. 165-172
-
-
von Minckwitz, G.1
Jonat, W.2
Fasching, P.3
-
144
-
-
23944464495
-
Phase II and tumor pharmacodynamic study of gefitinib in patients with advanced breast cancer
-
Baselga J, Albanell J, Ruiz A et al. Phase II and tumor pharmacodynamic study of gefitinib in patients with advanced breast cancer. J. Clin. Oncol. 23(23), 5323-5333 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.23
, pp. 5323-5333
-
-
Baselga, J.1
Albanell, J.2
Ruiz, A.3
-
145
-
-
35548961447
-
A mechanistic perspective of monoclonal antibodies in cancer therapy beyond target-related effects
-
Strome SE, Sausville EA, Mann D. A mechanistic perspective of monoclonal antibodies in cancer therapy beyond target-related effects. Oncologist 12(9), 1084-1095 (2007).
-
(2007)
Oncologist
, vol.12
, Issue.9
, pp. 1084-1095
-
-
Strome, S.E.1
Sausville, E.A.2
Mann, D.3
-
146
-
-
34547697317
-
Antibodies to the epidermal growth factor receptor in non small cell lung cancer: Current status of matuzumab and panitumumab
-
Socinski MA. Antibodies to the epidermal growth factor receptor in non small cell lung cancer: current status of matuzumab and panitumumab. Clin. Cancer Res. 13(15 Pt 2), S4597-S4601 (2007).
-
(2007)
Clin. Cancer Res
, vol.13
, Issue.15 PART 2
-
-
Socinski, M.A.1
-
147
-
-
0016756272
-
Continuous cultures of fused cells secreting antibody of predefined specificity
-
Kohler G, Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256(5517), 495-497(1975).
-
(1975)
Nature
, vol.256
, Issue.5517
, pp. 495-497
-
-
Kohler, G.1
Milstein, C.2
-
148
-
-
35948977282
-
Resistance to an irreversible epidermal growth factor receptor (EGFR) inhibitor in EGFR-mutant lung cancer reveals novel treatment strategies
-
Yu Z, Boggon TJ, Kobayashi S et al. Resistance to an irreversible epidermal growth factor receptor (EGFR) inhibitor in EGFR-mutant lung cancer reveals novel treatment strategies. Cancer Res. 67(21), 10417-10427(2007).
-
(2007)
Cancer Res
, vol.67
, Issue.21
, pp. 10417-10427
-
-
Yu, Z.1
Boggon, T.J.2
Kobayashi, S.3
-
149
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
Romond EH, Perez EA, Bryant J et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N. Engl. J. Med. 353(16), 1673-1684 (2005).
-
(2005)
N. Engl. J. Med
, vol.353
, Issue.16
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
-
150
-
-
33748525213
-
Adjuvant therapy with trastuzumab for HER-2/neu-positive breast cancer
-
Gonzalez-Angulo AM, Hortobagyi GN, Esteva FJ. Adjuvant therapy with trastuzumab for HER-2/neu-positive breast cancer. Oncologist 11(8), 857-867 (2006).
-
(2006)
Oncologist
, vol.11
, Issue.8
, pp. 857-867
-
-
Gonzalez-Angulo, A.M.1
Hortobagyi, G.N.2
Esteva, F.J.3
-
151
-
-
31644439702
-
Herceptin: Mechanisms of action and resistance
-
Nahta R, Esteva FJ. Herceptin: mechanisms of action and resistance. Cancer Lett. 232(2), 123-138 (2006).
-
(2006)
Cancer Lett
, vol.232
, Issue.2
, pp. 123-138
-
-
Nahta, R.1
Esteva, F.J.2
-
152
-
-
33749011681
-
A Phase I study of cetuximab/paclitaxel in patients with advanced-stage breast cancer
-
Modi S, D'Andrea G, Norton L et al. A Phase I study of cetuximab/paclitaxel in patients with advanced-stage breast cancer. Clin. Breast Cancer 7(3), 270-277 (2006).
-
(2006)
Clin. Breast Cancer
, vol.7
, Issue.3
, pp. 270-277
-
-
Modi, S.1
D'Andrea, G.2
Norton, L.3
-
153
-
-
34547096751
-
Breast cancer expressing the activated HER2/neu is sensitive to gefitinib in vitro and in vivo and acquires resistance through a novel point mutation in the HER2/neu
-
Piechocki MP, Yoo GH, Dibbley SK, Lonardo F Breast cancer expressing the activated HER2/neu is sensitive to gefitinib in vitro and in vivo and acquires resistance through a novel point mutation in the HER2/neu. Cancer Res. 67(14), 6825-6843 (2007).
-
(2007)
Cancer Res
, vol.67
, Issue.14
, pp. 6825-6843
-
-
Piechocki, M.P.1
Yoo, G.H.2
Dibbley, S.K.3
Lonardo, F.4
-
154
-
-
52949127301
-
Breast cancer cells with acquired resistance to the EGFR tyrosine kinase inhibitor gefitinib show persistent activation of MAPK signaling
-
Epub ahead of print
-
Normanno N, Campiglio M, Maiello MR et al. Breast cancer cells with acquired resistance to the EGFR tyrosine kinase inhibitor gefitinib show persistent activation of MAPK signaling. Breast Cancer Res. Treat. (2007) (Epub ahead of print).
-
(2007)
Breast Cancer Res. Treat
-
-
Normanno, N.1
Campiglio, M.2
Maiello, M.R.3
-
155
-
-
25844467036
-
Overview of tyrosine kinase inhibitors in clinical breast cancer
-
Agrawal A, Gutteridge E, Gee JM, Nicholson RI, Robertson JF. Overview of tyrosine kinase inhibitors in clinical breast cancer. Endocr. Relat. Cancer 12(Suppl. 1), S135-S144 (2005).
-
(2005)
Endocr. Relat. Cancer
, vol.12
, Issue.SUPPL. 1
-
-
Agrawal, A.1
Gutteridge, E.2
Gee, J.M.3
Nicholson, R.I.4
Robertson, J.F.5
-
156
-
-
35248889408
-
EGFR associated expression profiles vary with breast tumor subtype
-
Hoadley KA, Weigman VJ, Fan C et al. EGFR associated expression profiles vary with breast tumor subtype. BMC Genomics 8, 258 (2007).
-
(2007)
BMC Genomics
, vol.8
, pp. 258
-
-
Hoadley, K.A.1
Weigman, V.J.2
Fan, C.3
-
157
-
-
39749085432
-
Short preoperative treatment with erlotinib inhibits tumor cell proliferation in hormone receptor-positive breast cancers
-
Guix M, Granja Nde M, Meszoely I et al. Short preoperative treatment with erlotinib inhibits tumor cell proliferation in hormone receptor-positive breast cancers. J. Clin. Oncol. 26(6), 897-906 (2008).
-
(2008)
J. Clin. Oncol
, vol.26
, Issue.6
, pp. 897-906
-
-
Guix, M.1
Granja Nde, M.2
Meszoely, I.3
-
158
-
-
33751344602
-
HER2 therapy: Molecular mechanisms of trastuzumab resistance
-
Nahta R, Esteva FJ. HER2 therapy: molecular mechanisms of trastuzumab resistance. Breast Cancer Res. 8 (6), 215 (2006).
-
(2006)
Breast Cancer Res
, vol.8
, Issue.6
, pp. 215
-
-
Nahta, R.1
Esteva, F.J.2
-
159
-
-
32244435355
-
Mechanisms of trastuzumab resistance and their clinical implications
-
Lan KH, Lu CH, Yu D. Mechanisms of trastuzumab resistance and their clinical implications. Ann. NY Acad. Sci. 1059, 70-75 (2005).
-
(2005)
Ann. NY Acad. Sci
, vol.1059
, pp. 70-75
-
-
Lan, K.H.1
Lu, C.H.2
Yu, D.3
-
160
-
-
12544250996
-
Decreased accessibility and lack of activation of ErbB2 in JIMT-1, a herceptin-resistant, MUC4-expressing breast cancer cell line
-
Nagy P, Friedlander E, Tanner M et al. Decreased accessibility and lack of activation of ErbB2 in JIMT-1, a herceptin-resistant, MUC4-expressing breast cancer cell line. Cancer Res. 65(2), 473-482 (2005).
-
(2005)
Cancer Res
, vol.65
, Issue.2
, pp. 473-482
-
-
Nagy, P.1
Friedlander, E.2
Tanner, M.3
-
161
-
-
34247588567
-
Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer
-
Scaltriti M, Rojo F, Ocana A et al. Expression of p95HER2, a truncated form of the HER2 receptor, and response to anti-HER2 therapies in breast cancer. J. Natl Cancer Inst. 99(8), 628-638 (2007)
-
(2007)
J. Natl Cancer Inst
, vol.99
, Issue.8
, pp. 628-638
-
-
Scaltriti, M.1
Rojo, F.2
Ocana, A.3
-
162
-
-
43049106865
-
Evaluation of serum HER2 extracellular domain in early breast cancer patients: Correlation with clinicopathological parameters and survival
-
Ludovini V, Gori S, Colozza M et al. Evaluation of serum HER2 extracellular domain in early breast cancer patients: correlation with clinicopathological parameters and survival. Ann. Oncol. 19(5), 883-890 (2008).
-
(2008)
Ann. Oncol
, vol.19
, Issue.5
, pp. 883-890
-
-
Ludovini, V.1
Gori, S.2
Colozza, M.3
-
163
-
-
5144226211
-
PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
-
Nagata Y, Lan KH, Zhou X et al. PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 6(2), 117-127(2004).
-
(2004)
Cancer Cell
, vol.6
, Issue.2
, pp. 117-127
-
-
Nagata, Y.1
Lan, K.H.2
Zhou, X.3
-
164
-
-
31444444131
-
PTEN activity could be a predictive marker of trastuzumab efficacy in the treatment of ErbB2-overexpressing breast cancer
-
Fujita T, Doihara H, Kawasaki K et al. PTEN activity could be a predictive marker of trastuzumab efficacy in the treatment of ErbB2-overexpressing breast cancer. Br. J. Cancer 94(2), 247-252 (2006).
-
(2006)
Br. J. Cancer
, vol.94
, Issue.2
, pp. 247-252
-
-
Fujita, T.1
Doihara, H.2
Kawasaki, K.3
-
165
-
-
13844317894
-
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib
-
Kobayashi S, Boggon TJ, Dayaram T et al. EGFR mutation and resistance of non-small-cell lung cancer to gefitinib. N. Engl. J. Med. 352(8), 786-792 (2005).
-
(2005)
N. Engl. J. Med
, vol.352
, Issue.8
, pp. 786-792
-
-
Kobayashi, S.1
Boggon, T.J.2
Dayaram, T.3
-
166
-
-
33846566408
-
Dual inhibition of ErbBl (EGFR/HER1) and ErbB2 (HER2/neu)
-
Reid A, Vidal L, Shaw H, de Bono J. Dual inhibition of ErbBl (EGFR/HER1) and ErbB2 (HER2/neu). Eur. J. Cancer 43(3), 481-489 (2007).
-
(2007)
Eur. J. Cancer
, vol.43
, Issue.3
, pp. 481-489
-
-
Reid, A.1
Vidal, L.2
Shaw, H.3
de Bono, J.4
-
167
-
-
20244388653
-
Study of the biologic effects of lapatinib, a reversible inhibitor of ErbB 1 and ErbB2 tyrosine kinases, on tumor growth and survival pathways in patients with advanced malignancies
-
Spector NL, Xia W, Burris H III et al. Study of the biologic effects of lapatinib, a reversible inhibitor of ErbB 1 and ErbB2 tyrosine kinases, on tumor growth and survival pathways in patients with advanced malignancies. J. Clin. Oncol. 23(11), 2502-2512 (2005).
-
(2005)
J. Clin. Oncol
, vol.23
, Issue.11
, pp. 2502-2512
-
-
Spector, N.L.1
Xia, W.2
Burris III, H.3
-
168
-
-
32944461545
-
Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells
-
Konecny GE, Pegram MD, Venkatesan N et al. Activity of the dual kinase inhibitor lapatinib (GW572016) against HER-2-overexpressing and trastuzumab-treated breast cancer cells. Cancer Res. 66(3), 1630-1639 (2006).
-
(2006)
Cancer Res
, vol.66
, Issue.3
, pp. 1630-1639
-
-
Konecny, G.E.1
Pegram, M.D.2
Venkatesan, N.3
-
169
-
-
34548433016
-
Clinical strategies for rationale combinations of aromatase inhibitors with novel therapies for breast cancer
-
Johnston SR, Martin LA, Leary A, Head J, Dowsett M. Clinical strategies for rationale combinations of aromatase inhibitors with novel therapies for breast cancer. J. Steroid Biochem. Mol Biol. 106(1-5), 180-186 (2007).
-
(2007)
J. Steroid Biochem. Mol Biol
, vol.106
, Issue.1-5
, pp. 180-186
-
-
Johnston, S.R.1
Martin, L.A.2
Leary, A.3
Head, J.4
Dowsett, M.5
-
170
-
-
35748937088
-
Lapatinib in breast cancer
-
Bilancia D, Rosati G, Dinota A et al. Lapatinib in breast cancer. Ann. Oncol. (18 Suppl. 6), vi26-vi30 (2007).
-
(2007)
Ann. Oncol
, vol.18
, Issue.SUPPL. 6
-
-
Bilancia, D.1
Rosati, G.2
Dinota, A.3
-
171
-
-
33845886440
-
Lapatinib plus capecitabine for HER2-positive advanced breast cancer
-
Geyer CE, Forster J, Lindquist D et al. Lapatinib plus capecitabine for HER2-positive advanced breast cancer. N. Engl J. Med. 355(26), 2733-2743 (2006).
-
(2006)
N. Engl J. Med
, vol.355
, Issue.26
, pp. 2733-2743
-
-
Geyer, C.E.1
Forster, J.2
Lindquist, D.3
-
172
-
-
1942474587
-
The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells
-
Nahta R, Hung MC, Esteva FJ. The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells. Cancer Res. 64(7), 2343-2346 (2004).
-
(2004)
Cancer Res
, vol.64
, Issue.7
, pp. 2343-2346
-
-
Nahta, R.1
Hung, M.C.2
Esteva, F.J.3
-
173
-
-
35748935901
-
-
Carteni G, Fiorentino R, Vecchione L, Chiurazzi B, Battista C. Panitumumab a novel drug in cancer treatment. Ann. Oncol. (18 Suppl. 6), vil6-vi21 (2007).
-
Carteni G, Fiorentino R, Vecchione L, Chiurazzi B, Battista C. Panitumumab a novel drug in cancer treatment. Ann. Oncol. (18 Suppl. 6), vil6-vi21 (2007).
-
-
-
|