Fenugreek lactone attenuates palmitate-induced apoptosis and dysfunction in pancreatic β-cells

World Journal of Gastroenterology

Volumn 21, Issue 48, 2015, Pages 13457-13465

  Gong, Jing ^a   Dong, Hui ^a   Jiang, Shu Jun ^a   Wang, Ding Kun ^a   Fang, Ke ^a   Yang, De Sen ^b   Zou, Xin ^a   Xu, Li Jun ^a   Wang, Kai Fu ^a   Lu, Fu Er ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b HUBEI UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Apoptosis; Diabetes; Fenugreek lactone; Insulin secretion; Oxidative stress

Indexed keywords

BETA ACTIN; CASPASE 3; CATALASE; FAT DROPLET; GLUTATHIONE PEROXIDASE; INSULIN; LACTONE; MALONALDEHYDE; MESSENGER RNA; PALMITIC ACID; PROTEIN KINASE C ALPHA; PROTEIN P47; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; ANTIDIABETIC AGENT; ANTIOXIDANT; BIOLOGICAL MARKER; CASP3 PROTEIN, MOUSE; NEUTROPHIL CYTOSOLIC FACTOR 1; PLANT EXTRACT; PRKCA PROTEIN, MOUSE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL VIABILITY; COLORIMETRY; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; FENUGREEK; FLOW CYTOMETRY; GENE EXPRESSION; INSULIN RELEASE; LIPID STORAGE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PROTEIN PHOSPHORYLATION; RADIOIMMUNOASSAY; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; ANIMAL; CELL PROTECTION; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; ISOLATION AND PURIFICATION; METABOLISM; PATHOLOGY; PHOSPHORYLATION; SECRETION (PROCESS); SIGNAL TRANSDUCTION; TRIGONELLA; TUMOR CELL LINE;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BIOMARKERS; CASPASE 3; CELL LINE, TUMOR; CELL SURVIVAL; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; HYPOGLYCEMIC AGENTS; INSULIN; INSULIN-SECRETING CELLS; LACTONES; MICE; NADPH OXIDASE; OXIDATIVE STRESS; PALMITIC ACID; PHOSPHORYLATION; PLANT EXTRACTS; PROTEIN KINASE C-ALPHA; SIGNAL TRANSDUCTION; TRIGLYCERIDES; TRIGONELLA;

EID: 84953206036     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v21.i48.13457     Document Type: Article

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