Protective effect of Trigonella foenum-graecum Linn. on monosodium glutamate-induced dyslipidemia and oxidative stress in rats

Indian Journal of Pharmacology

Volumn 45, Issue 2, 2013, Pages 136-140

  Kumar, Parveen ^a   Bhandari, Uma ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Antihyperlipidemic; monosodium glutamate; neonatal; oxidative stress; Trigonella foenum graecum

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CATALASE; GLUTAMATE SODIUM; GLUTATHIONE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LACTATE DEHYDROGENASE; LIPID PEROXIDE; SUPEROXIDE DISMUTASE; TETRAHYDROLIPSTATIN; TRIACYLGLYCEROL; TRIGONELLA FOENUM GRAECUM EXTRACT;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS SOLUTION; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG EFFECT; DYSLIPIDEMIA; ENZYME BLOOD LEVEL; FENUGREEK; LACTATE DEHYDROGENASE BLOOD LEVEL; NEWBORN; NONHUMAN; OXIDATIVE STRESS; PHYTOCHEMISTRY; RAT; TRIACYLGLYCEROL BLOOD LEVEL;

ANTIHYPERLIPIDEMIC; MONOSODIUM GLUTAMATE; NEONATAL; OXIDATIVE STRESS; TRIGONELLA FOENUM-GRAECUM;

ANIMALS; ANTI-OBESITY AGENTS; BIOLOGICAL MARKERS; CHOLESTEROL; DYSLIPIDEMIAS; FLAVORING AGENTS; LACTONES; OXIDATIVE STRESS; PLANT EXTRACTS; RATS; RATS, WISTAR; SEEDS; SODIUM GLUTAMATE; TRIGLYCERIDES; TRIGONELLA;

EID: 84875991185     PISSN: 02537613     EISSN: 19983751     Source Type: Journal    
DOI: 10.4103/0253-7613.108288     Document Type: Article

References (41)

1. Schaumburg HH, Byck R, Gerstl R, Mashman JH. Monosodium L-glutamate: Its pharmacology and role in the Chineserestaurant syndrome. Science 1969;163:826-8
2. Park CH, Choi SH, Piao Y, Kim S,Lee YJ,Kim HS, et al. Glutamate and aspartate impair memory retention and damage hypothalamic neurons in adult mice. Toxicol Lett 2000;115:117-25
3. Singh P, Mann KA, Mangat HK, Kaur G. Prolonged glutamate excitotoxicity: Effects on mitochondrial antioxidants and antioxidant enzymes. Mol Cell Biochem 2003;243:139-45
4. Gobatto CA,Mello MA,Souza CT,Ribeiro IA. The monosodium glutamate (MSG) obese rat as a model for the study of exercise in obesity. Res Commun Mol Pathol Pharmacol 2002;111:89-101
5. Diniz YS, Fernandes AA, Campos KE, Mani F, Ribas BO, Novelli EL. Toxicity of hyper caloricdiet and monoso diumglutamate: Oxidative stress and metabolic shifting in hepatictissue. Food Chem Toxicol 2004;42:313-9
6. Abdel Baky NA, Mohamed AM, Faddah LM. Protective effect of N-Acetyl cysteine and/or pro vitamin A against monosodium glutamate-induced cardiopathy in rats. J Pharmacol Toxicol 2009;4:178-93
7. Soliman AM. Extract of Coelaturaaegyptiaca, a freshwater clam, ameliorates hepatic oxidative stress induced by monosodium glutamate in rats. Afr J Pharm Pharmacol 2011;5:398-408
8. Foyer CH, Pellny TK, Locato V, De Gara L. Analysis of redox relationships in the plant cell cycle: Determinations of ascorbate, glutathione and poly (ADPribose) polymerase (PARP) in plant cell cultures. Methods Mol Biol 2009;476:193-209
9. Minibayeva F, Kolesnikov O, Chasov A, Beckett RP, Lüthje S,Vylegzhanina N, et al. Wound-induced apoplastic peroxidase activities: Their roles in the production and detoxification of reactive oxygen species. Plant Cell Environ 2009;32:497-508
10. Kaviarasan S, Ramamurty N, Gunasekaran P, Varalakshmi E, Anuradha CV. Fenugreek (Trigonellafoenumgraecum) seed prevents ethanol-induced toxicity and apoptosis in Chang liver cells. Alcohol Alcohol 2006;41:267-73
11. Zia T, Hasnain SN, Hasan SK. Evaluation of the oral hypoglycaemic effect of Trigonella foenum-graecum L. (methi) in normal mice. J Ethnopharmacol 2001;75:191-5
12. Hannan JM, Ali L, Rokeya B, Khaleque J, Akhter M, Flatt PR, et al. Soluble dietary fibre fraction of Trigonella foenum-graecum (fenugreek) seed improves glucose homeostasis in animal models of type 1 and type 2 diabetes by delaying carbohydrate digestion and absorption, and enhancing insulin action. Br J Nutr 2007;97:514-21
13. Kokate CK. Practical pharmacognosy. 4thed. New Delhi: Vallabh Prakashan; 1994. p. 107-11
14. Li PP, Shan S, Chen YT, Ning ZQ, Sun SJ, Liu Q, et al. The PPAR alpha/gamma dual agonist chiglitazar improves insulin resistance and dyslipidemia in MSG obese rats. Br J Pharmacol 2006;148:610-8
15. Oluba O, Onyeneke E, Idonije B, Eidangbe G. Effect of soy protein on monosodium glutamate (MSG)-induced obesity in rats. Asian J Phar Biol Res 2011;1:8-14
16. Wybenga DR, Pileggi VJ, Dirstine PH, Di Giorgio J. Direct manual determination of serum total cholesterol with a single stable reagent. Clin Chem 1970; 16:980-4
17. Stein EA, Myers GL. National Cholesterol Education Program recommendations for triglyceride measurement: Executive summary. The National Cholesterol Education Program Working Group on Lipoprotein Measurement. Clin Chem 1995;41:1421-6
18. Lum G, Gambino SR. A comparison of serum versus heparinized plasma for routine chemistry tests. Am J Clin Pathol 1974;61:108-13
19. Rietman S, Frankel S. A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases. Am J Clin Pathol 1957;28:56-63
20. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Bio Chem 1979;95:351-8
21. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 1951;193:265-75
22. Sedlak J, Lindsay RH. Estimation of total, protein bound and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem 1968;25:192-205
23. Marklund S, Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Bio Chem1974;47:469-74
24. Clairborne A. Catalase activity. In: Greenwald RA, editor. CRC Handbook of methods for oxygen radical research. Boca Raton, Florida, USA: CRC Press; 1985. pp. 283-4
25. Malik VB, Ahluwalia P. Studies on effect of monosodium glutamate (MSG) on various fractions of lipids and certain carbohydrate metabolic enzymes in liver and blood of adult male mice. Toxicol Lett 1994;74:69-77
26. Ahluwalia P, Tewari K, Choudhary P. Studies on the effects of monosodium glutamate (MSG) on oxidative stress in erythrocytes of adult male mice. Toxicol Lett 1996;84:161-5
27. Andersen JK. Oxidative stress in neurodegeneration: Cause or consequence? Nat Med 2004;10Suppl:S18-25
28. Onyema OO, Farombi EO, Emerole GO, Ukoha AI, Onyeze GO. Effect of vitamin E on monosodium glutamate induced hepatotoxicity and oxidative stress in rats. Indian J Biochem Biophys 2006;43:20-4
29. Rizvi F, Iftikhar M, George JP. Beneficial effects of fish liver preparations of sea bass (Lates calcarifer) versus gemfibrozil in high fat diet-induced lipid-intolerant rats. J Med Food 2003;6:123-8
30. Vijayakumar RS, Nalini N. Efficacy of piperine, an alkaloidal constituent from Piper nigrum on erythrocyte antioxidant status in high fat diet and antithyroid drug induced hyperlipidemic rats. Cell Bio Chem Funct 2006;24:491-8
31. Liou W, Chang LY, Geuze HJ, Strous GJ, Crapo JD, Slot JW. Distribution of CuZn superoxide dismutase in rat liver. Free Radic Biol Med 1993;14:201-7
32. Al-Mamary M, Al-Habori M, Al-Aghbari AM, Baker MM. Investigation into the toxicological effects of Catha edulis leaves: A short term study in animals. Phytother Res 2002;16:127-32
33. Bain PJ. Liver. In: Latimer KS, Mahaffey EA, Prasse KW, editors. Duncan and Prasse's Veterinary Laboratory Medicine: Clinical Pathology,4thed. Ames, Iowa:Iowa State Press; 2003. p. 193-214
34. Pari L, Murugan P. Protective role of tetrahydrocurcumin against erythromycin estolate- induced hepatotoxicity. Pharmacol Res 2004;49:481-6
35. Farombi EO, Onyema OO. Monosodium glutamate-induced oxidative damage and genotoxicity in the rat: Modulatory role of vitamin C, vitamin E and quercetin. Hum Exp Toxicol 2006;25:251-9
36. Harlan JM, Levine JD, Callahan KS, Schwartz BR, Harker LA. Glutathione redox cycle protects cultured endothelial cells against lysis by extracellularly generated hydrogen peroxide. J Clin Invest 1984;73:706-13
37. Hiraishi H, Terano A, Ota S, Mutoh H, Sugimoto T, Harada T, et al. Protection of cultured rat gastric cells against oxidant-induced damage by exogenous glutathione. Gastroenterology 1994;106:1199-207
38. Zelko IN, Mariani TJ, Folz RJ. Superoxide dismutase multigene family: A comparison of the CuZn-SOD (SOD1), Mn-SOD (SOD2), and EC-SOD (SOD3) gene structures, evolution, and expression. Free Radic Biol Med 2002;33:337-49
39. Chelikani P, Fita I, Loewen PC. Diversity of structures and properties among catalases. Cell Mol Life Sci 2004;61:192-208
40. Oakenfull DG, Fenwick DE, Hood RL, Topping DL, Illman RL, Storer GB. Effects of saponins on bile acids and plasma lipids in the rats. Br J Nutr 1979;42:209-16
41. Hamden K, Jaouadi B, Salami T, Carreau S, Bejar S, Elfeki A. Modulatory effect of fenugreek saponins on the activities of intestinal and hepatic disaccharidase and glycogen and liver function of diabetic rats. Biotechnol Bioprocess Eng 2010;15:745-53