Functional response of the isolated, perfused normoxic heart to pyruvate dehydrogenase activation by dichloroacetate and pyruvate

Pflugers Archiv European Journal of Physiology

Volumn 468, Issue 1, 2016, Pages 131-142

  Jaimes, Rafael ^a   Kuzmiak Glancy, Sarah ^a   Brooks, Daina M ^a   Swift, Luther M ^b   Posnack, Nikki G ^b   Kay, Matthew W ^a,b  

^a The George Washington University   (United States)

^b GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

Author keywords

Cardiac; Dichloroacetate; NADH; Pyruvate dehydrogenase

Indexed keywords

DICHLOROACETIC ACID; GLUCOSE; LACTIC ACID; PYRUVATE DEHYDROGENASE; PYRUVIC ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE; CALCIUM; NICOTINAMIDE ADENINE DINUCLEOTIDE; PYRUVATE DEHYDROGENASE COMPLEX;

ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVATION; HEART CONTRACTION; HEART FUNCTION; HEART MUSCLE CONTRACTILITY; HEART PERFUSION; HEART RATE; HEART VENTRICLE EXTRASYSTOLE; INCIDENCE; INTRACELLULAR SIGNALING; ISOLATED HEART; MITOCHONDRIAL RESPIRATION; MUSCLE CELL; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; CARDIAC MUSCLE; DRUG EFFECTS; HEART; HEART VENTRICLE FUNCTION; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; CALCIUM; DICHLOROACETIC ACID; GLUCOSE; HEART; ISOLATED HEART PREPARATION; MYOCARDIAL CONTRACTION; MYOCARDIUM; NAD; PYRUVATE DEHYDROGENASE COMPLEX; PYRUVIC ACID; RATS; RATS, SPRAGUE-DAWLEY; VENTRICULAR FUNCTION;

EID: 84952989834     PISSN: 00316768     EISSN: 14322013     Source Type: Journal    
DOI: 10.1007/s00424-015-1717-1     Document Type: Article

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