Metabolic phenotyping of the diseased rat heart using 13C-substrates and ex vivo perfusion in the working mode

Molecular and Cellular Biochemistry

Volumn 242, Issue 1-2, 2003, Pages 89-99

  Vincent, Geneviève ^a   Khairallah, Maya ^a   Bouchard, Bertrand ^b   Des Rosiers, Christine ^a,b  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF MONTREAL   (Canada)

Author keywords

Citrate release; Citric acid cycle; Energy metabolism; Isotopomer analysis; SHR hearts; Substrate flux parameters

Indexed keywords

BUFFER; CARBOHYDRATE; CARBON 13; CITRIC ACID; FATTY ACID; GLUCOSE; LACTIC ACID; OLEIC ACID; PYRUVIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOXYLATION; CITRIC ACID CYCLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DECARBOXYLATION; DISEASE MODEL; ENERGY METABOLISM; ESSENTIAL HYPERTENSION; FATTY ACID OXIDATION; GAS CHROMATOGRAPHY; GLYCOLYSIS; HEART FUNCTION; HEART MITOCHONDRION; HEART MUSCLE ISCHEMIA; HEART MUSCLE METABOLISM; HEART MUSCLE OXYGEN CONSUMPTION; HEART MUSCLE PERFUSION; HEART PERFORMANCE; LYSIS; MASS SPECTROMETRY; NONHUMAN; PHENOTYPE; RAT; RAT STRAIN; SPONTANEOUSLY HYPERTENSIVE RAT; SYNTHESIS; TISSUE LEVEL; TISSUE NECROSIS; TRANSPORT KINETICS;

ANIMALS; CARBON ISOTOPES; CITRIC ACID; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; LACTOSE; MALE; MYOCARDIUM; OXYGEN CONSUMPTION; PERFUSION; PHENOTYPE; PYRUVIC ACID; RATS;

ANIMALIA;

EID: 0037283852     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1021189728877     Document Type: Article

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