메뉴 건너뛰기




Volumn 8, Issue 5, 2013, Pages

The Positive Inotropic Effect of Pyruvate Involves an Increase in Myofilament Calcium Sensitivity

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CYCLOPIAZONIC ACID; FURA 2; POTASSIUM; PYRUVIC ACID; RYANODINE; THAPSIGARGIN;

EID: 84877777155     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0063608     Document Type: Article
Times cited : (16)

References (49)
  • 2
    • 0008340411 scopus 로고    scopus 로고
    • Haemodynamic effects of intracoronary pyruvate in patients with congestive heart failure: an open study
    • Hermann HP, Pieske B, Schwarzmuller E, Keul J, Just H, et al. (1999) Haemodynamic effects of intracoronary pyruvate in patients with congestive heart failure: an open study. Lancet 353: 1321-1323.
    • (1999) Lancet , vol.353 , pp. 1321-1323
    • Hermann, H.P.1    Pieske, B.2    Schwarzmuller, E.3    Keul, J.4    Just, H.5
  • 3
    • 34547675937 scopus 로고    scopus 로고
    • Influence of pyruvate on economy of contraction in isolated rabbit myocardium
    • Keweloh B, Janssen PM, Siegel U, Datz N, Zeitz O, et al. (2007) Influence of pyruvate on economy of contraction in isolated rabbit myocardium. Eur J Heart Fail 9: 754-761.
    • (2007) Eur J Heart Fail , vol.9 , pp. 754-761
    • Keweloh, B.1    Janssen, P.M.2    Siegel, U.3    Datz, N.4    Zeitz, O.5
  • 4
    • 1342345252 scopus 로고    scopus 로고
    • Improved systolic and diastolic myocardial function with intracoronary pyruvate in patients with congestive heart failure
    • Hermann HP, Arp J, Pieske B, Kogler H, Baron S, et al. (2004) Improved systolic and diastolic myocardial function with intracoronary pyruvate in patients with congestive heart failure. Eur J Heart Fail 6: 213-218.
    • (2004) Eur J Heart Fail , vol.6 , pp. 213-218
    • Hermann, H.P.1    Arp, J.2    Pieske, B.3    Kogler, H.4    Baron, S.5
  • 6
    • 0018072217 scopus 로고
    • Effects of buffered pyruvate on regional cardiac function in moderate, short-term ischemia in swine heart
    • Liedtke AJ, Nellis SH, (1978) Effects of buffered pyruvate on regional cardiac function in moderate, short-term ischemia in swine heart. Circ Res 43: 189-199.
    • (1978) Circ Res , vol.43 , pp. 189-199
    • Liedtke, A.J.1    Nellis, S.H.2
  • 7
  • 8
    • 0036135854 scopus 로고    scopus 로고
    • Potentiation of beta-adrenergic inotropic response by pyruvate in failing human myocardium
    • Hermann HP, Zeitz O, Lehnart SE, Keweloh B, Datz N, et al. (2002) Potentiation of beta-adrenergic inotropic response by pyruvate in failing human myocardium. Cardiovasc Res 53: 116-123.
    • (2002) Cardiovasc Res , vol.53 , pp. 116-123
    • Hermann, H.P.1    Zeitz, O.2    Lehnart, S.E.3    Keweloh, B.4    Datz, N.5
  • 9
    • 79957514840 scopus 로고    scopus 로고
    • Intracoronary pyruvate in cardiogenic shock as an adjunctive therapy to catecholamines and intra-aortic balloon pump shows beneficial effects on hemodynamics
    • Schillinger W, Hunlich M, Sossalla S, Hermann HP, Hasenfuss G, (2011) Intracoronary pyruvate in cardiogenic shock as an adjunctive therapy to catecholamines and intra-aortic balloon pump shows beneficial effects on hemodynamics. Clin Res Cardiol 100: 433-438.
    • (2011) Clin Res Cardiol , vol.100 , pp. 433-438
    • Schillinger, W.1    Hunlich, M.2    Sossalla, S.3    Hermann, H.P.4    Hasenfuss, G.5
  • 10
    • 0033672337 scopus 로고    scopus 로고
    • Antioxidant pyruvate inhibits cardiac formation of reactive oxygen species through changes in redox state
    • Bassenge E, Sommer O, Schwemmer M, Bunger R, (2000) Antioxidant pyruvate inhibits cardiac formation of reactive oxygen species through changes in redox state. Am J Physiol Heart Circ Physiol 279: H2431-2438.
    • (2000) Am J Physiol Heart Circ Physiol , vol.279
    • Bassenge, E.1    Sommer, O.2    Schwemmer, M.3    Bunger, R.4
  • 11
    • 0024600885 scopus 로고
    • Pyruvate-enhanced phosphorylation potential and inotropism in normoxic and postischemic isolated working heart. Near-complete prevention of reperfusion contractile failure
    • Bunger R, Mallet RT, Hartman DA, (1989) Pyruvate-enhanced phosphorylation potential and inotropism in normoxic and postischemic isolated working heart. Near-complete prevention of reperfusion contractile failure. Eur J Biochem 180: 221-233.
    • (1989) Eur J Biochem , vol.180 , pp. 221-233
    • Bunger, R.1    Mallet, R.T.2    Hartman, D.A.3
  • 12
    • 0027518190 scopus 로고
    • Pyruvate enhances recovery of rat hearts after ischemia and reperfusion by preventing free radical generation
    • DeBoer LW, Bekx PA, Han L, Steinke L, (1993) Pyruvate enhances recovery of rat hearts after ischemia and reperfusion by preventing free radical generation. Am J Physiol 265: H1571-1576.
    • (1993) Am J Physiol , vol.265
    • DeBoer, L.W.1    Bekx, P.A.2    Han, L.3    Steinke, L.4
  • 13
    • 0034910965 scopus 로고    scopus 로고
    • Sodium pyruvate is better than sodium chloride as a resuscitation solution in a rodent model of profound hemorrhagic shock
    • Slovin PN, Huang CJ, Cade JR, Wood CE, Nasiroglu O, et al. (2001) Sodium pyruvate is better than sodium chloride as a resuscitation solution in a rodent model of profound hemorrhagic shock. Resuscitation 50: 109-115.
    • (2001) Resuscitation , vol.50 , pp. 109-115
    • Slovin, P.N.1    Huang, C.J.2    Cade, J.R.3    Wood, C.E.4    Nasiroglu, O.5
  • 14
    • 0041473930 scopus 로고    scopus 로고
    • Pyruvate modulates cardiac sarcoplasmic reticulum Ca2+ release in rats via mitochondria-dependent and -independent mechanisms
    • Zima AV, Kockskamper J, Mejia-Alvarez R, Blatter LA, (2003) Pyruvate modulates cardiac sarcoplasmic reticulum Ca2+ release in rats via mitochondria-dependent and-independent mechanisms. J Physiol 550: 765-783.
    • (2003) J Physiol , vol.550 , pp. 765-783
    • Zima, A.V.1    Kockskamper, J.2    Mejia-Alvarez, R.3    Blatter, L.A.4
  • 15
    • 0032895668 scopus 로고    scopus 로고
    • Mitochondrial metabolism of pyruvate is required for its enhancement of cardiac function and energetics
    • Mallet RT, Sun J, (1999) Mitochondrial metabolism of pyruvate is required for its enhancement of cardiac function and energetics. Cardiovasc Res 42: 149-161.
    • (1999) Cardiovasc Res , vol.42 , pp. 149-161
    • Mallet, R.T.1    Sun, J.2
  • 16
    • 0037080690 scopus 로고    scopus 로고
    • Influence of pyruvate on contractile performance and Ca(2+) cycling in isolated failing human myocardium
    • Hasenfuss G, Maier LS, Hermann HP, Luers C, Hunlich M, et al. (2002) Influence of pyruvate on contractile performance and Ca(2+) cycling in isolated failing human myocardium. Circulation 105: 194-199.
    • (2002) Circulation , vol.105 , pp. 194-199
    • Hasenfuss, G.1    Maier, L.S.2    Hermann, H.P.3    Luers, C.4    Hunlich, M.5
  • 17
    • 33646417619 scopus 로고    scopus 로고
    • Measurement of myofilament calcium sensitivity at physiological temperature in intact cardiac trabeculae
    • Varian KD, Raman S, Janssen PM, (2006) Measurement of myofilament calcium sensitivity at physiological temperature in intact cardiac trabeculae. Am J Physiol Heart Circ Physiol 290: H2092-2097.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290
    • Varian, K.D.1    Raman, S.2    Janssen, P.M.3
  • 18
    • 0022553693 scopus 로고
    • The force-frequency relationship in rat myocardium. The influence of muscle dimensions
    • Schouten VJ, ter Keurs HE, (1986) The force-frequency relationship in rat myocardium. The influence of muscle dimensions. Pflugers Arch 407: 14-17.
    • (1986) Pflugers Arch , vol.407 , pp. 14-17
    • Schouten, V.J.1    ter Keurs, H.E.2
  • 19
    • 0036772442 scopus 로고    scopus 로고
    • Physiological determinants of contractile force generation and calcium handling in mouse myocardium
    • Stull LB, Leppo M, Marban E, Janssen PML, (2002) Physiological determinants of contractile force generation and calcium handling in mouse myocardium. J Mol Cell Cardiol 34: 1367-1376.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 1367-1376
    • Stull, L.B.1    Leppo, M.2    Marban, E.3    Janssen, P.M.L.4
  • 20
    • 29944433957 scopus 로고    scopus 로고
    • Effect of muscle dimensions on trabecular contractile performance under physiological conditions
    • Raman S, Kelley MA, Janssen PM, (2006) Effect of muscle dimensions on trabecular contractile performance under physiological conditions. Pflugers Arch 451: 625-630.
    • (2006) Pflugers Arch , vol.451 , pp. 625-630
    • Raman, S.1    Kelley, M.A.2    Janssen, P.M.3
  • 21
    • 0026665940 scopus 로고
    • A method to reconstruct myocardial sarcomere lengths and orientations at transmural sites in beating canine hearts
    • Rodriguez EK, Hunter WC, Royce MJ, Leppo MK, Douglas AS, et al. (1992) A method to reconstruct myocardial sarcomere lengths and orientations at transmural sites in beating canine hearts. Am J Physiol 263: H293-306.
    • (1992) Am J Physiol , vol.263
    • Rodriguez, E.K.1    Hunter, W.C.2    Royce, M.J.3    Leppo, M.K.4    Douglas, A.S.5
  • 22
    • 0027512192 scopus 로고
    • Fluorescent properties of rat cardiac trabeculae microinjected with fura-2 salt
    • Backx PH, Ter Keurs HE, (1993) Fluorescent properties of rat cardiac trabeculae microinjected with fura-2 salt. Am J Physiol 264: H1098-1110.
    • (1993) Am J Physiol , vol.264
    • Backx, P.H.1    Ter Keurs, H.E.2
  • 23
    • 0036088280 scopus 로고    scopus 로고
    • Myofilament properties comprise the rate-limiting step for cardiac relaxation at body temperature in the rat
    • Janssen PM, Stull LB, Marban E, (2002) Myofilament properties comprise the rate-limiting step for cardiac relaxation at body temperature in the rat. Am J Physiol Heart Circ Physiol 282: H499-507.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Janssen, P.M.1    Stull, L.B.2    Marban, E.3
  • 24
    • 0026050850 scopus 로고
    • Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps
    • Lytton J, Westlin M, Hanley MR, (1991) Thapsigargin inhibits the sarcoplasmic or endoplasmic reticulum Ca-ATPase family of calcium pumps. J Biol Chem 266: 17067-17071.
    • (1991) J Biol Chem , vol.266 , pp. 17067-17071
    • Lytton, J.1    Westlin, M.2    Hanley, M.R.3
  • 25
    • 0029414782 scopus 로고
    • Use of thapsigargin to study Ca2+ homeostasis in cardiac cells
    • Rogers TB, Inesi G, Wade R, Lederer WJ, (1995) Use of thapsigargin to study Ca2+ homeostasis in cardiac cells. Biosci Rep 15: 341-349.
    • (1995) Biosci Rep , vol.15 , pp. 341-349
    • Rogers, T.B.1    Inesi, G.2    Wade, R.3    Lederer, W.J.4
  • 26
    • 65249177669 scopus 로고    scopus 로고
    • The positive force-frequency relationship is maintained in absence of sarcoplasmic reticulum function in rabbit, but not in rat myocardium
    • Monasky MM, Janssen PM, (2009) The positive force-frequency relationship is maintained in absence of sarcoplasmic reticulum function in rabbit, but not in rat myocardium. J Comp Physiol B 179: 469-479.
    • (2009) J Comp Physiol B , vol.179 , pp. 469-479
    • Monasky, M.M.1    Janssen, P.M.2
  • 27
    • 34250809531 scopus 로고    scopus 로고
    • Frequency-dependent acceleration of relaxation involves decreased myofilament calcium sensitivity
    • Varian KD, Janssen PM, (2007) Frequency-dependent acceleration of relaxation involves decreased myofilament calcium sensitivity. Am J Physiol Heart Circ Physiol 292: H2212-2219.
    • (2007) Am J Physiol Heart Circ Physiol , vol.292
    • Varian, K.D.1    Janssen, P.M.2
  • 28
    • 35348992614 scopus 로고    scopus 로고
    • Modulation of the rate of cardiac muscle contraction by troponin C constructs with various calcium binding affinities
    • Norman C, Rall JA, Tikunova SB, Davis JP, (2007) Modulation of the rate of cardiac muscle contraction by troponin C constructs with various calcium binding affinities. Am J Physiol Heart Circ Physiol 293: H2580-2587.
    • (2007) Am J Physiol Heart Circ Physiol , vol.293
    • Norman, C.1    Rall, J.A.2    Tikunova, S.B.3    Davis, J.P.4
  • 29
    • 84862023507 scopus 로고    scopus 로고
    • Engineered troponin C constructs correct disease-related cardiac myofilament calcium sensitivity
    • Liu B, Lee RS, Biesiadecki BJ, Tikunova SB, Davis JP, (2012) Engineered troponin C constructs correct disease-related cardiac myofilament calcium sensitivity. J Biol Chem 287: 20027-20036.
    • (2012) J Biol Chem , vol.287 , pp. 20027-20036
    • Liu, B.1    Lee, R.S.2    Biesiadecki, B.J.3    Tikunova, S.B.4    Davis, J.P.5
  • 30
    • 0037115194 scopus 로고    scopus 로고
    • Determinants of relaxation rate in rabbit skinned skeletal muscle fibres
    • Luo Y, Davis JP, Smillie LB, Rall JA, (2002) Determinants of relaxation rate in rabbit skinned skeletal muscle fibres. J Physiol 545: 887-901.
    • (2002) J Physiol , vol.545 , pp. 887-901
    • Luo, Y.1    Davis, J.P.2    Smillie, L.B.3    Rall, J.A.4
  • 31
    • 0026646783 scopus 로고
    • Myosin light chain 2 modulates calcium-sensitive cross-bridge transitions in vertebrate skeletal muscle
    • Metzger JM, Moss RL, (1992) Myosin light chain 2 modulates calcium-sensitive cross-bridge transitions in vertebrate skeletal muscle. Biophys J 63: 460-468.
    • (1992) Biophys J , vol.63 , pp. 460-468
    • Metzger, J.M.1    Moss, R.L.2
  • 32
    • 0037188409 scopus 로고    scopus 로고
    • Effect of hydrophobic residue substitutions with glutamine on Ca(2+) binding and exchange with the N-domain of troponin C
    • Tikunova SB, Rall JA, Davis JP, (2002) Effect of hydrophobic residue substitutions with glutamine on Ca(2+) binding and exchange with the N-domain of troponin C. Biochemistry. 41: 6697-6705.
    • (2002) Biochemistry , vol.41 , pp. 6697-6705
    • Tikunova, S.B.1    Rall, J.A.2    Davis, J.P.3
  • 33
    • 4143085980 scopus 로고    scopus 로고
    • Designing calcium-sensitizing mutations in the regulatory domain of cardiac troponin C
    • Tikunova SB, Davis JP, (2004) Designing calcium-sensitizing mutations in the regulatory domain of cardiac troponin C. J Biol Chem. 279: 35341-35352.
    • (2004) J Biol Chem , vol.279 , pp. 35341-35352
    • Tikunova, S.B.1    Davis, J.P.2
  • 34
    • 80053271980 scopus 로고    scopus 로고
    • Effects of increased systolic Ca(2)(+) and phospholamban phosphorylation during beta-adrenergic stimulation on Ca(2)(+) transient kinetics in cardiac myocytes
    • Roof SR, Shannon TR, Janssen PM, Ziolo MT, (2011) Effects of increased systolic Ca(2)(+) and phospholamban phosphorylation during beta-adrenergic stimulation on Ca(2)(+) transient kinetics in cardiac myocytes. Am J Physiol Heart Circ Physiol 301: H1570-1578.
    • (2011) Am J Physiol Heart Circ Physiol , vol.301
    • Roof, S.R.1    Shannon, T.R.2    Janssen, P.M.3    Ziolo, M.T.4
  • 35
    • 0034103666 scopus 로고    scopus 로고
    • Phosphorylation of phospholamban and troponin I in beta-adrenergic-induced acceleration of cardiac relaxation
    • Li L, Desantiago J, Chu G, Kranias EG, Bers DM, (2000) Phosphorylation of phospholamban and troponin I in beta-adrenergic-induced acceleration of cardiac relaxation. Am J Physiol Heart Circ Physiol 278: H769-779.
    • (2000) Am J Physiol Heart Circ Physiol , vol.278
    • Li, L.1    Desantiago, J.2    Chu, G.3    Kranias, E.G.4    Bers, D.M.5
  • 36
    • 0036702654 scopus 로고    scopus 로고
    • Frequency-dependent acceleration of relaxation in the heart depends on CaMKII, but not phospholamban
    • DeSantiago J, Maier LS, Bers DM, (2002) Frequency-dependent acceleration of relaxation in the heart depends on CaMKII, but not phospholamban. J Mol Cell Cardiol 34: 975-984.
    • (2002) J Mol Cell Cardiol , vol.34 , pp. 975-984
    • DeSantiago, J.1    Maier, L.S.2    Bers, D.M.3
  • 37
    • 0028271419 scopus 로고
    • Effects of phosphorylation of troponin I and C protein on isometric tension and velocity of unloaded shortening in skinned single cardiac myocytes from rats
    • Hofmann PA, Lange JH, 3rd (1994) Effects of phosphorylation of troponin I and C protein on isometric tension and velocity of unloaded shortening in skinned single cardiac myocytes from rats. Circ Res 74: 718-726.
    • (1994) Circ Res , vol.74 , pp. 718-726
    • Hofmann, P.A.1    Lange 3rd, J.H.2
  • 38
    • 0028174245 scopus 로고
    • Beta-adrenergic receptor stimulation increases unloaded shortening velocity of skinned single ventricular myocytes from rats
    • Strang KT, Sweitzer NK, Greaser ML, Moss RL, (1994) Beta-adrenergic receptor stimulation increases unloaded shortening velocity of skinned single ventricular myocytes from rats. Circ Res 74: 542-549.
    • (1994) Circ Res , vol.74 , pp. 542-549
    • Strang, K.T.1    Sweitzer, N.K.2    Greaser, M.L.3    Moss, R.L.4
  • 39
    • 77958063805 scopus 로고    scopus 로고
    • Kinetics of Cardiac Muscle Contraction and Relaxation are Linked and Determined by Properties of the Cardiac Sarcomere
    • Janssen PML, (2010) Kinetics of Cardiac Muscle Contraction and Relaxation are Linked and Determined by Properties of the Cardiac Sarcomere. Am J Physiol Heart Circ Physiol 299: H1092-1099.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299
    • Janssen, P.M.L.1
  • 40
    • 78649742900 scopus 로고    scopus 로고
    • 54th Bowditch Lecture: Myocardial contraction-relaxation coupling
    • Janssen PML, (2010) 54th Bowditch Lecture: Myocardial contraction-relaxation coupling. Am J Physiol Heart Circ Physiol 299: H1741-1749.
    • (2010) Am J Physiol Heart Circ Physiol , vol.299
    • Janssen, P.M.L.1
  • 41
    • 0036088280 scopus 로고    scopus 로고
    • Myofilament properties comprise the rate-limiting step for cardiac relaxation at body temperature in the rat
    • Janssen PML, Stull LB, Marban E, (2002) Myofilament properties comprise the rate-limiting step for cardiac relaxation at body temperature in the rat. Am J Physiol Heart Circ Physiol 282: H499-H507.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Janssen, P.M.L.1    Stull, L.B.2    Marban, E.3
  • 42
    • 0037403175 scopus 로고    scopus 로고
    • Cardiac myofilaments: mechanics and regulation
    • de Tombe PP, (2003) Cardiac myofilaments: mechanics and regulation. J Biomech 36: 721-730.
    • (2003) J Biomech , vol.36 , pp. 721-730
    • de Tombe, P.P.1
  • 43
    • 0027418622 scopus 로고
    • Transport of lactate and other monocarboxylates across mammalian plasma membranes
    • Poole RC, Halestrap AP, (1993) Transport of lactate and other monocarboxylates across mammalian plasma membranes. Am J Physiol 264: C761-782.
    • (1993) Am J Physiol , vol.264
    • Poole, R.C.1    Halestrap, A.P.2
  • 44
    • 0026088496 scopus 로고
    • Intracellular pH regulation in ferret ventricular muscle. The role of Na-H exchange and the influence of metabolic substrates
    • Blatter LA, McGuigan JA, (1991) Intracellular pH regulation in ferret ventricular muscle. The role of Na-H exchange and the influence of metabolic substrates. Circ Res 68: 150-161.
    • (1991) Circ Res , vol.68 , pp. 150-161
    • Blatter, L.A.1    McGuigan, J.A.2
  • 47
    • 0023655089 scopus 로고
    • Substrate-induced alterations of high energy phosphate metabolism and contractile function in the perfused heart
    • Zweier JL, Jacobus WE, (1987) Substrate-induced alterations of high energy phosphate metabolism and contractile function in the perfused heart. J Biol Chem 262: 8015-8021.
    • (1987) J Biol Chem , vol.262 , pp. 8015-8021
    • Zweier, J.L.1    Jacobus, W.E.2
  • 48
    • 0028337558 scopus 로고
    • Influence of phosphate and pH on myofibrillar ATPase activity and force in skinned cardiac trabeculae from rat
    • Ebus JP, Stienen GJ, Elzinga G, (1994) Influence of phosphate and pH on myofibrillar ATPase activity and force in skinned cardiac trabeculae from rat. J Physiol 476: 501-516.
    • (1994) J Physiol , vol.476 , pp. 501-516
    • Ebus, J.P.1    Stienen, G.J.2    Elzinga, G.3
  • 49
    • 0022560216 scopus 로고
    • The effects of inorganic phosphate and creatine phosphate on force production in skinned muscles from rat ventricle
    • Kentish JC, (1986) The effects of inorganic phosphate and creatine phosphate on force production in skinned muscles from rat ventricle. J Physiol 370: 585-604.
    • (1986) J Physiol , vol.370 , pp. 585-604
    • Kentish, J.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.