PML–RARa modulates the vascular signature of extracellular vesicles released by acute promyelocytic leukemia cells

Angiogenesis

Volumn 19, Issue 1, 2016, Pages 25-38

  Fang, Yi ^a,b   Garnier, Delphine ^a   Lee, Tae Hoon ^a   D’Asti, Esterina ^a   Montermini, Laura ^a   Meehan, Brian ^a   Rak, Janusz ^a  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Acute promyelocytic leukemia; Angiogenesis; Angiogenic signature; ATRA; Cancer biomarker; Endothelial cells; Exosomes; Extracellular RNA; Extracellular vesicles; Oncogene; PML RARa; Targeted agents; Tissue factor

Indexed keywords

EPHRIN RECEPTOR B4; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; ONCOPROTEIN; PROMYELOCYTIC LEUKEMIA RETINOIC ACID RECEPTOR ALPHA; RETINOIC ACID; THROMBOPLASTIN; UNCLASSIFIED DRUG; VASCULOTROPIN; MESSENGER RNA; PROMYELOCYTIC LEUKEMIA-RETINOIC ACID RECEPTOR ALPHA FUSION ONCOPROTEIN; SIGNAL PEPTIDE;

ARTICLE; CELL MIGRATION; CELL TRACKING; CELLULAR PARAMETERS; CONTROLLED STUDY; CYTOKINE RELEASE; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; ENDOTHELIUM CELL; EXOSOME; FUSION GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE TRANSFER; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL LINE; NB4 CELL LINE; NUCLEAR REPROGRAMMING; PML RARA GENE; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; UPREGULATION; VESICULATION; BLOOD CLOTTING; DRUG EFFECTS; GENETICS; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; SECRETION (PROCESS); TUMOR CELL LINE; ULTRASTRUCTURE; UMBILICAL VEIN ENDOTHELIAL CELL;

BLOOD COAGULATION; CELL LINE, TUMOR; EXTRACELLULAR VESICLES; GENE EXPRESSION REGULATION, LEUKEMIC; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LEUKEMIA, PROMYELOCYTIC, ACUTE; NEOVASCULARIZATION, PATHOLOGIC; ONCOGENE PROTEINS, FUSION; RNA, MESSENGER; THROMBOPLASTIN; TRETINOIN;

EID: 84952984378     PISSN: 09696970     EISSN: 15737209     Source Type: Journal    
DOI: 10.1007/s10456-015-9486-1     Document Type: Article

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