Oncogenic ras-driven cancer cell vesiculation leads to emission of double-stranded DNA capable of interacting with target cells

Biochemical and Biophysical Research Communications

Volumn 451, Issue 2, 2014, Pages 295-301

  Lee, Tae Hoon ^a   Chennakrishnaiah, Shilpa ^a   Audemard, Eric ^b   Montermini, Laura ^a   Meehan, Brian ^a   Rak, Janusz ^a  

^a MONTREAL CHILDREN S HOSPITAL   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

Chromatin; DNA; Extracellular vesicle; Oncogene; Ras; Sphingomyelinase

Indexed keywords

DOUBLE STRANDED DNA; HISTONE; PROTEIN P53; RETINOBLASTOMA PROTEIN; SPHINGOMYELIN PHOSPHODIESTERASE;

ANIMAL CELL; ARTICLE; CANCER CELL; CELL INTERACTION; CELL PROLIFERATION; CELL VACUOLE; COPY NUMBER VARIATION; DNA HISTONE INTERACTION; DNA SEQUENCE; HOST CELL; INTESTINE EPITHELIUM CELL; NONHUMAN; ONCOGENE RAS; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TARGET CELL;

RATTUS;

CHROMATIN; DNA; EXTRACELLULAR VESICLE; ONCOGENE; RAS; SPHINGOMYELINASE;

ANIMALS; ANTIGENS, POLYOMAVIRUS TRANSFORMING; CELL LINE; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; CHROMATIN; DNA; DNA, NEOPLASM; EXOSOMES; GENES, RAS; GENOME, HUMAN; HUMANS; INTESTINAL MUCOSA; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MUTATION; PROTO-ONCOGENE PROTEINS P21(RAS); RATS; SPHINGOMYELIN PHOSPHODIESTERASE;

EID: 84906934030     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.07.109     Document Type: Article

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