The opioid-sparing effect of intraoperative dexmedetomidine infusion after craniotomy

Journal of Neurosurgical Anesthesiology

Volumn 28, Issue 1, 2016, Pages 14-20

  Song, Jie ^a   Ji, Qing ^a   Sun, Qing ^a   Gao, Tao ^a   Liu, Kui ^a   Li, Li ^a  

^a TIANJIN UNION MEDICAL CENTER   (China)

Author keywords

craniotomy; dexmedetomidine; postoperative pain; sedation

Indexed keywords

DEXMEDETOMIDINE; MORPHINE; OPIATE; PLACEBO; PROPOFOL; REMIFENTANIL; ANALGESIC AGENT; NARCOTIC ANALGESIC AGENT;

ADULT; AGITATION; ARTICLE; CONTROLLED STUDY; CRANIOTOMY; DRUG EFFECT; ENDOTRACHEAL INTUBATION; FEMALE; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; PATIENT CONTROLLED ANALGESIA; POSTOPERATIVE ANALGESIA; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PAIN; PRIORITY JOURNAL; PRURITUS; RAMSAY SEDATION SCALE; RANDOMIZED CONTROLLED TRIAL; ADOLESCENT; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE AGED; PAIN, POSTOPERATIVE; PEROPERATIVE CARE; PROCEDURES; STATISTICS AND NUMERICAL DATA; YOUNG ADULT;

ADOLESCENT; ADULT; ANALGESIA, PATIENT-CONTROLLED; ANALGESICS, NON-NARCOTIC; ANALGESICS, OPIOID; CRANIOTOMY; DEXMEDETOMIDINE; FEMALE; HUMANS; INFUSIONS, INTRAVENOUS; INTRAOPERATIVE CARE; MALE; MIDDLE AGED; MORPHINE; PAIN, POSTOPERATIVE; YOUNG ADULT;

EID: 84952981255     PISSN: 08984921     EISSN: 15371921     Source Type: Journal    
DOI: 10.1097/ANA.0000000000000190     Document Type: Article

References (34)

1. Verchère E, Grenier B, Mesli A, et al. Postoperative pain management after supratentorial craniotomy. J Neurosurg Anesthesiol. 2002;14:96-101.
2. Gray LC, Matta BF. Acute and chronic pain following craniotomy: a review. Anaesthesia. 2005;60:693-704.
3. Rozet I. Anesthesia for functional neurosurgery: the role of dexmedetomidine. Curr Opin Anaesthesiol. 2008;21:537-543.
4. Ha SH, Park IH, Lee MH, et al. Use of dexmedetomidine for awake crainiotomy. Korean J Anesthesiol. 2011;61:346-347.
5. Bekker A, Sturaitis MK. Dexmedetomidine for neurological surgery. Neurosurgery. 2005;57:1-10.
6. Hall JE, Uhrich TD, Barney JA, et al. Sedative, amnestic, and analgesic properties of small-dose dexmedetomidine infusions. Anesth Analg. 2000;90:699-705.
7. Venn RM, Bradshaw CJ, Spencer R, et al. Preliminary UK experience of dexmedetomidine, a novel agent for postoperative sedation in the intensive care unit. Anaesthesia. 1999;54:1136-1142.
8. Bekker A, Haile M, Kline R, et al. The effect of intraoperative infusion of dexmedetomidine on the quality of recovery after major spinal surgery. J Neurosurg Anesthesiol. 2013;25:16-24.
9. Sudheer PS, Logan SW, Terblanche C, et al. Comparison of the analgesic efficacy and respiratory effects of morphine, tramadol and codeine after craniotomy. Anaesthesia. 2007;62:555-560.
10. MacLaren R, Krisl JC, Cochrane RE, et al. A case-based approach to the practical application of dexmedetomidine in critically ill adults. Pharmacotherapy. 2013;33:165-186.
11. Guen M, Liu N, Tounou F, et al. Dexmedetomidine reduces propofol and remifentanil requirements during bispectral indexguided closed-loop anesthesia: a double-blind, placebocontrolled trial. Anesth Analg. 2014;118:946-955.
12. Zhang C, Hu J, Liu X, et al. Effects of intravenous dexmedetomidine on emergence agitation in children under sevoflurane anesthesia: a meta-analysis of randomized controlled trials. PLoS One. 2014;9:e99718.
13. Demuro JP, Botros D, Nedeau E, et al. Use of dexmedetomidine for postoperative analgesia in spine patients. J Neurosurg Sci. 2013;57:171-174.
14. Niu XY, Ding XB, Guo T, et al. Effects of intravenous and intrathecal dexmedetomidine in spinal anesthesia: a meta-analysis. CNS Neurosci Ther. 2013;19:897-904.
15. Abdallah FW, Abrishami A, Brull R. The facilitatory effects of intravenous dexmedetomidine on the duration of spinal anesthesia: a systematic review and meta-analysis. Anesth Analg. 2013;117:271-278.
16. Reddy VS, Shaik NA, Donthu B, et al. Intravenous dexmedetomidine versus clonidine for prolongation of bupivacaine spinal anesthesia and analgesia: a randomized double-blind study. J Anaesthesiol Clin Pharmacol. 2013;29:342-347.
17. Ebert TJ, Hall JE, Barney JA, et al. The effects of increasing plasma concentrations of dexmedetomidine in humans. Anesthesiology. 2000;93:382-394.
18. Feld JM, Hoffman WE, Stechert MM, et al. Fentanyl or dexmedetomidine combined with desflurane for bariatric surgery. J Clin Anesth. 2006;18:24-28.
19. Reardon DP, Anger KE, Adams CD, et al. Role of dexmedetomidine in adults in the intensive care unit: an update. Am J Health Syst Pharm. 2013;70:767-777.
20. Shen SL, Zheng JY, Zhang J, et al. Comparison of dexmedetomidine and propofol for conscious sedation in awake craniotomy: a prospective, double-blind, randomized, and controlled clinical trial. Ann Pharmacother. 2013;47:1391-1399.
21. Goodwin HE, Gill RS, Murakami PN, et al. Dexmedetomidine preserves attention/calculation when used for cooperative and shortterm intensive care unit sedation. J Crit Care. 2013;28: 1113.e7-1113.e10.
22. Cohen MB, Stewart JT. Treatment of post-electroconvulsive therapy agitation with dexmedetomidine. J ECT. 2013;29:e23-e24.
23. Bryson EO, Briggs MC, Pasculli RM, et al. Treatment-resistant postictal agitation after electroconvulsive therapy (ECT) controlled with dexmedetomidine. J ECT. 2013;29:e18.
24. Xia ZQ, Chen SQ, Yao X, et al. Clinical benefits of dexmedetomidine versus propofol in adult intensive care unit patients: a metaanalysis of randomized clinical trials. J Surg Res. 2013;185: 833-843.
25. Chen JY, Jia JE, Liu TJ, et al. Comparison of the effects of dexmedetomidine, ketamine, and placebo on emergence agitation after strabismus surgery in children. Can J Anaesth. 2013;60:385-392.
26. Mo Y, Zimmermann AE. Role of dexmedetomidine for the prevention and treatment of delirium in intensive care unit patients. Ann Pharmacother. 2013;47:869-876.
27. Jakob SM, Ruokonen E, Takala J. Efficacy of dexmedetomidine compared with midazolam for sedation in adult intensive care patients. Br J Anaesth. 2014;112:581-582.
28. Pasin L, Greco T, Feltracco P, et al. Dexmedetomidine as a sedative agent in critically ill patients: a meta-analysis of randomized controlled trials. PLoS One. 2013;8:e82931.
29. Bhana N, Goa KL, McClellan KJ. Dexmedetomidine. Drugs. 2000;59:263-268.
30. Huncke TK, Adelman M, Jacobowita G, et al. A prospective, randomized, placebo-controlled study evaluating the efficacy of dexmedetomidine for sedation during vascular procedures. Vasc Endovascular Surg. 2010;44:257-261.
31. Lin L, Guo X, Zhang MZ, et al. Pharmacokinetics of dexmedetomidine in Chinese post-surgical intensive care unit patients. Acta Anaesthesiol Scand. 2011;55:359-367.
32. Talke P, Richardson CA, Scheinin M, et al. Postoperative pharmacokinetics and sympatholytic effects of dexmedetomidine. Anesth Analg. 1997;85:1136-1142.
33. Iirola T, Ihmsen H, Laitio R, et al. Population pharmacokinetics of dexmedetomidine during long-term sedation in intensive care patients. Br J Anaesth. 2012;108:460-468.
34. Mariappan R, Ashokkumar H, Kuppuswamy B. Comparing the effects of oral clonidine premedication with intraoperative dexmedetomidine infusion on anesthetic requirement and recovery from anesthesia in patients undergoing major spine surgery. J Neurosurg Anesthesiol. 2014;26:192-197.