Effects of intravenous dexmedetomidine on emergence agitation in children under sevoflurane anesthesia: A meta-analysis of randomized controlled trials

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Zhang, Chengliang ^a   Hu, Jiajia ^a   Liu, Xinyao ^b   Yan, Jianqin ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DEXMEDETOMIDINE; PLACEBO; SEVOFLURANE; ETHER DERIVATIVE; INTRAVENOUS ANESTHETIC AGENT;

AGITATION; ARTICLE; BRADYCARDIA; DELAYED EMERGENCE FROM ANESTHESIA; EMERGENCE AGITATION; EXTUBATION; HUMAN; HYPOTENSION; LENGTH OF STAY; META ANALYSIS; OXYGEN DESATURATION; PEDIATRIC ANESTHESIA; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PAIN; RANDOMIZED CONTROLLED TRIAL (TOPIC); RECOVERY ROOM; RESPIRATION DEPRESSION; UNSPECIFIED SIDE EFFECT; INTRAVENOUS ANESTHESIA; PAIN, POSTOPERATIVE; PSYCHOMOTOR AGITATION; PUBLISHING; TIME;

AIRWAY EXTUBATION; ANESTHESIA, INTRAVENOUS; ANESTHETICS, INTRAVENOUS; DEXMEDETOMIDINE; HUMANS; LENGTH OF STAY; METHYL ETHERS; PAIN, POSTOPERATIVE; POSTOPERATIVE NAUSEA AND VOMITING; PSYCHOMOTOR AGITATION; PUBLICATION BIAS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TIME FACTORS;

EID: 84903275401     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0099718     Document Type: Article

References (48)

1. Yamashita M (2003) Postanaesthetic excitation and agitation. Paediatr Anaesth 13: 641, 642-643.
2. Eger EN (2004) Characteristics of anesthetic agents used for induction and maintenance of general anesthesia. Am J Health Syst Pharm 61 Suppl 4: S3-S10.
3. Vlajkovic GP, Sindjelic RP (2007) Emergence delirium in children: many questions, few answers. Anesth Analg 104: 84-91. (Pubitemid 46360426)
4. Aono J, Ueda W, Mamiya K, Takimoto E, Manabe M (1997) Greater incidence of delirium during recovery from sevoflurane anesthesia in preschool boys. Anesthesiology 87: 1298-1300. (Pubitemid 28007323)
5. Kuratani N, Oi Y (2008) Greater incidence of emergence agitation in children after sevoflurane anesthesia as compared with halothane: a meta-analysis of randomized controlled trials. Anesthesiology 109: 225-232.
6. Dahmani S, Stany I, Brasher C, Lejeune C, Bruneau B, et al. (2010) Pharmacological prevention of sevoflurane- and desflurane-related emergence agitation in children: a meta-analysis of published studies. Br J Anaesth 104: 216-223.
7. Bhana N, Goa KL, McClellan KJ (2000) Dexmedetomidine. Drugs 59: 263-268, 269-270.
8. Su F, Hammer GB (2011) Dexmedetomidine: pediatric pharmacology, clinical uses and safety. Expert Opin Drug Saf 10: 55-66.
9. Isik B, Arslan M, Tunga AD, Kurtipek O (2006) Dexmedetomidine decreases emergence agitation in pediatric patients after sevoflurane anesthesia without surgery. Paediatr Anaesth 16: 748-753. (Pubitemid 44365964)
10. Ibacache ME, Munoz HR, Brandes V, Morales AL (2004) Single-dose dexmedetomidine reduces agitation after sevoflurane anesthesia in children. Anesth Analg 98: 60-63. (Pubitemid 38029843)
11. Guler G, Akin A, Tosun Z, Ors S, Esmaoglu A, et al. (2005) Single-dose dexmedetomidine reduces agitation and provides smooth extubation after pediatric adenotonsillectomy. Paediatr Anaesth 15: 762-766. (Pubitemid 43960893)
12. Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gotzsche PC, et al. (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. PLoS Med 6: e1000100.
13. Moher D, Liberati A, Tetzlaff J, Altman DG (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 151: 264-269, W64.
14. Higgins JP, Altman DG, Gotzsche PC, Juni P, Moher D, et al. (2011) The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ 343: d5928.
15. Higgins JP, Green S (2008) Included, Assessing Risk Of Bias Studies. In: JPT H, S G, 'editors. Cochrane handbook for systematic reviews of interventions: Wiley Online Library. pp. 187-241.
16. Ali MA, Abdellatif AA (2013) Prevention of sevoflurane related emergence agitation in children undergoing adenotonsillectomy: A comparison of dexmedetomidine and propofol. Saudi J Anaesth 7: 296-300.
17. Chen JY, Jia JE, Liu TJ, Qin MJ, Li WX (2013) Comparison of the effects of dexmedetomidine, ketamine, and placebo on emergence agitation after strabismus surgery in children. Can J Anaesth 60: 385-392.
18. Erdil F, Demirbilek S, Begec Z, Ozturk E, Ulger MH, et al. (2009) The effects of dexmedetomidine and fentanyl on emergence characteristics after adenoidectomy in children. Anaesth Intensive Care 37: 571-576.
19. He L, Wang X, Zheng S, Shi Y (2013) Effects of dexmedetomidine infusion on laryngeal mask airway removal and postoperative recovery in children anaesthetised with sevoflurane. Anaesth Intensive Care 41: 328-333.
20. Lili X, Jianjun S, Haiyan Z (2012) The application of dexmedetomidine in children undergoing vitreoretinal surgery. J Anesth 26: 556-561.
21. Sato M, Shirakami G, Tazuke-Nishimura M, Matsuura S, Tanimoto K, et al. (2010) Effect of single-dose dexmedetomidine on emergence agitation and recovery profiles after sevoflurane anesthesia in pediatric ambulatory surgery. J Anesth 24: 675-682.
22. Gupta N, Rath GP, Prabhakar H, Dash HH (2013) Effect of intraoperative dexmedetomidine on postoperative recovery profile of children undergoing surgery for spinal dysraphism. J Neurosurg Anesthesiol 25: 271-278.
23. Meng QT, Xia ZY, Luo T, Wu Y, Tang LH, et al. (2012) Dexmedetomidine reduces emergence agitation after tonsillectomy in children by sevoflurane anesthesia: a case-control study. Int J Pediatr Otorhinolaryngol 76: 1036-1041.
24. Shukry M, Clyde MC, Kalarickal PL, Ramadhyani U (2005) Does dexmedetomidine prevent emergence delirium in children after sevoflurane-based general anesthesia? Paediatr Anaesth 15: 1098-1104. (Pubitemid 43965389)
25. Higgins JP, Green S (2008) How to include multiple groups from one study. Cochrane handbook for systematic reviews of interventions: Wiley Online Library. pp. 412-413.
26. Kanaya A, Kuratani N, Satoh D, Kurosawa S (2013) Lower incidence of emergence agitation in children after propofol anesthesia compared with sevoflurane: a meta-analysis of randomized controlled trials. J Anesth.
27. Przybylo HJ, Martini DR, Mazurek AJ, Bracey E, Johnsen L, et al. (2003) Assessing behaviour in children emerging from anaesthesia: can we apply psychiatric diagnostic techniques? Paediatr Anaesth 13: 609-616. (Pubitemid 37153471)
28. Welborn LG, Hannallah RS, Norden JM, Ruttimann UE, Callan CM (1996) Comparison of emergence and recovery characteristics of sevoflurane, desflurane, and halothane in pediatric ambulatory patients. Anesth Analg 83: 917-920. (Pubitemid 26365400)
29. Aouad MT, Nasr VG (2005) Emergence agitation in children: an update. Curr Opin Anaesthesiol 18: 614-619. (Pubitemid 41689640)
30. Bortone L, Ingelmo P, Grossi S, Grattagliano C, Bricchi C, et al. (2006) Emergence agitation in preschool children: double-blind, randomized, controlled trial comparing sevoflurane and isoflurane anesthesia. Paediatr Anaesth 16: 1138-1143. (Pubitemid 44581641)
31. Cohen IT, Finkel JC, Hannallah RS, Hummer KA, Patel KM (2003) Rapid emergence does not explain agitation following sevoflurane anaesthesia in infants and children: a comparison with propofol. Paediatr Anaesth 13: 63-67. (Pubitemid 36115003)
32. Cohen IT, Hannallah RS, Hummer KA (2001) The incidence of emergence agitation associated with desflurane anesthesia in children is reduced by fentanyl. Anesth Analg 93: 88-91. (Pubitemid 32601159)
33. Moore JK, Moore EW, Elliott RA, St LA, Payne K, et al. (2003) Propofol and halothane versus sevoflurane in paediatric day-case surgery: induction and recovery characteristics. Br J Anaesth 90: 461-466. (Pubitemid 36432437)
34. Aono J, Mamiya K, Manabe M (1999) Preoperative anxiety is associated with a high incidence of problematic behavior on emergence after halothane anesthesia in boys. Acta Anaesthesiol Scand 43: 542-544. (Pubitemid 29232722)
35. Finkel JC, Cohen IT, Hannallah RS, Patel KM, Kim MS, et al. (2001) The effect of intranasal fentanyl on the emergence characteristics after sevoflurane anesthesia in children undergoing surgery for bilateral myringotomy tube placement. Anesth Analg 92: 1164-1168. (Pubitemid 32385936)
36. Cohen IT, Finkel JC, Hannallah RS, Hummer KA, Patel KM (2002) The effect of fentanyl on the emergence characteristics after desflurane or sevoflurane anesthesia in children. Anesth Analg 94: 1178-1181. (Pubitemid 34441831)
37. Galinkin JL, Fazi LM, Cuy RM, Chiavacci RM, Kurth CD, et al. (2000) Use of intranasal fentanyl in children undergoing myringotomy and tube placement during halothane and sevoflurane anesthesia. Anesthesiology 93: 1378-1383.
38. Kamibayashi T, Maze M (2000) Clinical uses of alpha2 -adrenergic agonists. Anesthesiology 93: 1345-1349.
39. Ebert TJ, Hall JE, Barney JA, Uhrich TD, Colinco MD (2000) The effects of increasing plasma concentrations of dexmedetomidine in humans. Anesthesiology 93: 382-394. (Pubitemid 30620311)
40. Arain SR, Ruehlow RM, Uhrich TD, Ebert TJ (2004) The efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery. Anesth Analg 98: 153-158. (Pubitemid 38029869)
41. Unlugenc H, Gunduz M, Guler T, Yagmur O, Isik G (2005) The effect of preanaesthetic administration of intravenous dexmedetomidine on postoperative pain in patients receiving patient-controlled morphine. Eur J Anaesthesiol 22: 386-391. (Pubitemid 40676796)
42. Venn RM, Karol MD, Grounds RM (2002) Pharmacokinetics of dexmedetomidine infusions for sedation of postoperative patients requiring intensive caret. Br J Anaesth 88: 669-675. (Pubitemid 34498595)
43. Blaudszun G, Lysakowski C, Elia N, Tramer MR (2012) Effect of perioperative systemic alpha2 agonists on postoperative morphine consumption and pain intensity: systematic review and meta-analysis of randomized controlled trials. Anesthesiology 116: 1312-1322.
44. Mason KP, Lerman J (2011) Review article: Dexmedetomidine in children: current knowledge and future applications. Anesth Analg 113: 1129-1142.
45. Tobias JD (2007) Dexmedetomidine: applications in pediatric critical care and pediatric anesthesiology. Pediatr Crit Care Med 8: 115-131.
46. Lin TF, Yeh YC, Lin FS, Wang YP, Lin CJ, et al. (2009) Effect of combining dexmedetomidine and morphine for intravenous patient-controlled analgesia. Br J Anaesth 102: 117-122.
47. Kallio A, Scheinin M, Koulu M, Ponkilainen R, Ruskoaho H, et al. (1989) Effects of dexmedetomidine, a selective alpha 2-adrenoceptor agonist, on hemodynamic control mechanisms. Clin Pharmacol Ther 46: 33-42. (Pubitemid 19195772)
48. Reardon DP, Anger KE, Adams CD, Szumita PM (2013) Role of dexmedetomidine in adults in the intensive care unit: an update. Am J Health Syst Pharm 70: 767-777.