Efficacy of dexmedetomidine compared with midazolam for sedation in adult intensive care patients

British Journal of Anaesthesia

Volumn 112, Issue 3, 2014, Pages 581-582

  Jakob, S M ^a   Ruokonen, E ^a   Takala, J ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

DEXMEDETOMIDINE; MIDAZOLAM;

ARTIFICIAL VENTILATION; CONSCIOUS SEDATION; DRUG EFFICACY; HUMAN; INTENSIVE CARE UNIT; LETTER; PATIENT SAFETY; PRIORITY JOURNAL; SEDATION;

CONSCIOUS SEDATION; DEXMEDETOMIDINE; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; MIDAZOLAM; PREGNANCY;

EID: 84896866736     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aeu032     Document Type: Letter

References (7)

1. Adams R, Brown GT, Davidson M, et al. Efficacyofdexmedetomidine compared with midazolam for sedation in adult intensive care patients: a systematic review. Br J Anaesth 2013; 111: 703-10
2. Ruokonen E, Parviainen I, Jakob SM, et al. Dexmedetomidine versus propofol/midazolamforlong-termsedationduringmechanicalven-tilation. Intensive Care Med 2009; 35: 282-90
3. Jakob SM, Ruokonen E, Grounds RM, et al. Dexmedetomidinevs. mid-azolam or propofol for sedation during prolonged mechanical ventilation: two randomized controlled trials. J Am Med Assoc 2012; 307: 1151-60
4. Senoglu N, Oksuz H, Dogan Z, Yildiz H, Demirkiran H, Ekerbicer H. Sedation during noninvasive mechanical ventilation with dexmede-tomidine or midazolam: a randomized, double-blind, prospective study. Cur Ther Res Clin Exp 2010; 71: 141-53
5. Haenggi M, Ypparila-Wolters H, Buerki S, et al. Auditoryevent-related potentials, bispectral index, andentropy for the discriminationofdif-ferent levels of sedationin intensive care unit patients. Anesth Analg 2009; 109: 807-16
6. Haenggi M, Ypparila-Wolters H, Hauser K, et al. Intra-and inter-individual variation of BIS-index and Entropy during controlled sedation with midazolam/remifentanil and dexmedetomidine/remifentanil in healthy volunteers: an interventional study. Crit Care 2009; 13: R20
7. Sessler CN, Gosnell MS, Grap MJ, et al. The Richmond Agitation-Sedation Scale: validity and reliability in adult intensive care unit patients. Am J Respir Crit Care Med 2002; 166: 1338-44