CSF1 Restores Innate Immunity after Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients with Acute Liver Failure

Gastroenterology

Volumn 149, Issue 7, 2015, Pages 1896-1909.e14

  Stutchfield, Benjamin M ^a,b   Antoine, Daniel J ^b   Mackinnon, Alison C ^a   Gow, Deborah J ^c   Bain, Calum C ^f   Hawley, Catherine A ^d   Hughes, Michael J ^b   Francis, Benjamin ^g   Wojtacha, Davina ^a   Man, Tak Y ^a   Dear, James W ^b   Devey, Luke R ^d   Mowat, Alan M ^f   Pollard, Jeffrey W ^e   Park, B Kevin ^b   Jenkins, Stephen J ^d   Simpson, Kenneth J ^b   Hume, David A ^b   Wigmore, Stephen J ^b   Forbes, Stuart J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d UNIVERSITY OF EDINBURGH   (United Kingdom)

^e UNIVERSITY OF EDINBURGH   (United Kingdom)

^f UNIVERSITY OF GLASGOW   (United Kingdom)

^g UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Clearance; Drug Induced Liver Damage; Immune Response; M CSF

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CHEMOKINE RECEPTOR CCR2; COLONY STIMULATING FACTOR 1; HIGH MOBILITY GROUP B1 PROTEIN; MACROPHAGE DERIVED CHEMOKINE; MESSENGER RNA; MONOCYTE CHEMOTACTIC PROTEIN 3; MONOCYTE CHEMOTACTIC PROTEIN 5; PARACETAMOL; COLONY STIMULATING FACTOR;

ACUTE LIVER FAILURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CELL PROLIFERATION; CELL TRANSDIFFERENTIATION; CONTROLLED STUDY; HUMAN; INNATE IMMUNITY; INTOXICATION; LIVER INJURY; LIVER SURGERY; LIVER TOXICITY; MACROPHAGE; MAJOR CLINICAL STUDY; MALE; MONOCYTE; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PARTIAL HEPATECTOMY; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; WILD TYPE; ANIMAL; C57BL MOUSE; DRUG EFFECTS; IMMUNOLOGY; LIVER;

ANIMALS; CELL TRANSDIFFERENTIATION; COLONY-STIMULATING FACTORS; HUMANS; IMMUNITY, INNATE; LIVER; LIVER FAILURE, ACUTE; MACROPHAGES; MICE; MICE, INBRED C57BL;

EID: 84952928093     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2015.08.053     Document Type: Article

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