Curcumin prevents inflammatory response, oxidative stress and insulin resistance in high fructose fed male Wistar rats: Potential role of serine kinases

Chemico-Biological Interactions

Volumn 244, Issue , 2016, Pages 187-194

  Maithilikarpagaselvi, Nachimuthu ^a   Sridhar, Magadi Gopalakrishna ^a   Swaminathan, Rathinam Palamalai ^a   Zachariah, Bobby ^a  

^a JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Curcumin; Fructose rich diet; Insulin sensitivity; Low grade inflammation; Metabolic derangement; Oxidative stress

Indexed keywords

C REACTIVE PROTEIN; CURCUMIN; CYCLOOXYGENASE 2; FRUCTOSE; GLUTATHIONE PEROXIDASE; I KAPPA B ALPHA; INSULIN RECEPTOR SUBSTRATE 1; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE C THETA; PROTEIN SERINE KINASE; SYNAPTOPHYSIN; TUMOR NECROSIS FACTOR ALPHA; NONSTEROID ANTIINFLAMMATORY AGENT; PROTEIN SERINE THREONINE KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; DRUG MECHANISM; GLUCOSE INTOLERANCE; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; GLUCOSE TOLERANCE TEST; METABOLISM; PHOSPHORYLATION; STRUCTURE ACTIVITY RELATION; WISTAR RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CURCUMIN; FRUCTOSE; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; INFLAMMATION; INSULIN RESISTANCE; MALE; OXIDATIVE STRESS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RATS; RATS, WISTAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84952682943     PISSN: 00092797     EISSN: 18727786     Source Type: Journal    
DOI: 10.1016/j.cbi.2015.12.012     Document Type: Article

References (43)

1. L. Guariguata, D.R. Whiting, I. Hambleton, J. Beagley, U. Linnenkamp, and J.E. Shaw Global estimates of diabetes prevalence for 2013 and projections for 2035 Diabetes Res. Clin. Pract. 103 2014 137 149
2. R.A. DeFronzo, E. Jacot, E. Jequier, E. Maeder, J. Wahren, and J.P. Felber The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization Diabetes 30 1981 1000 1007
3. A. Misra, and L. Khurana Obesity and the metabolic syndrome in developing countries J. Clin. Endocrinol. Metab. 93 2008 S9 S30
4. P.M. Gerrits, and E. Tsalikian Diabetes and fructose metabolism Am. J. Clin. Nutr. 58 1993 796S 799S
5. M. Brownlee Biochemistry and molecular cell biology of diabetic complications Nature 414 2001 813 820
6. J.A. McCubrey, M.M. Lahair, and R.A. Franklin Reactive oxygen species-induced activation of the MAP kinase signaling pathways Antioxid. Redox Signal 8 2006 1775 1789
7. J.-F. Tanti, and J. Jager Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation Curr. Opin. Pharmacol. 9 2009 753 762
8. S.K. Jain, J. Rains, J. Croad, B. Larson, and K. Jones Curcumin supplementation lowers TNF-α, IL-6, IL-8, and MCP-1 secretion in high glucose-treated cultured monocytes and blood levels of TNF-α, IL-6, MCP-1, glucose, and glycosylated hemoglobin in diabetic rats Antioxid. Redox Signal 11 2009 241 249
9. M. Kuroda, Y. Mimaki, T. Nishiyama, T. Mae, H. Kishida, M. Tsukagawa, and et al. Hypoglycemic effects of turmeric (Curcuma longa L. rhizomes) on genetically diabetic KK-Ay mice Biol. Pharm. Bull. 28 2005 937 939
10. K.-I. Seo, M.-S. Choi, U.J. Jung, H.-J. Kim, J. Yeo, S.-M. Jeon, and et al. Effect of curcumin supplementation on blood glucose, plasma insulin, and glucose homeostasis related enzyme activities in diabetic db/db mice Mol. Nutr. Food Res. 52 2008 995 1004
11. J.-M. Li, Y.-C. Li, L.-D. Kong, and Q.-H. Hu Curcumin inhibits hepatic protein-tyrosine phosphatase 1B and prevents hypertriglyceridemia and hepatic steatosis in fructose-fed rats Hepatol. Balt. Md. 51 2010 1555 1566
12. I.S. Hwang, H. Ho, B.B. Hoffman, and G.M. Reaven Fructose-induced insulin resistance and hypertension in rats Hypertension 1987 512 516 n.d.
13. L.-X. Na, Y.-L. Zhang, Y. Li, L.-Y. Liu, R. Li, T. Kong, and et al. Curcumin improves insulin resistance in skeletal muscle of rats Nutr. Metab. Cardiovasc. Dis. NMCD 21 2011 526 533
14. M. Yuan, N. Konstantopoulos, J. Lee, L. Hansen, Z.W. Li, M. Karin, and et al. Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta Science 293 2001 1673 1677
15. B.-W. Huang, M.-T. Chiang, H.-T. Yao, and W. Chiang The effect of high-fat and high-fructose diets on glucose tolerance and plasma lipid and leptin levels in rats Diabetes Obes. Metab. 6 2004 120 126
16. D.R. Matthews, J.P. Hosker, A.S. Rudenski, B.A. Naylor, D.F. Treacher, and R.C. Turner Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 28 1985 412 419
17. J. Folch, M. Lees, and G.H. Sloane Stanley A simple method for the isolation and purification of total lipides from animal tissues, J. Biol. Chem. 226 1957 497 509
18. J.A. Buege, and S.D. Aust Microsomal lipid peroxidation Methods Enzymol. 52 1978 302 310
19. O. Erel A new automated colorimetric method for measuring total oxidant status Clin. Biochem. 38 2005 1103 1111
20. O.H. Lowry, N.J. Rosebrough, A.L. Farr, and R.J. Randall Protein measurement with the Folin phenol reagent J. Biol. Chem. 193 1951 265 275
21. R. Padiya, T.N. Khatua, P.K. Bagul, M. Kuncha, and S.K. Banerjee Garlic improves insulin sensitivity and associated metabolic syndromes in fructose fed rats Nutr. Metab. 8 2011 53
22. M.G. Tordoff, and A.M. Alleva Effect of drinking soda sweetened with aspartame or high-fructose corn syrup on food intake and body weight Am. J. Clin. Nutr. 51 1990 963 969
23. O.G. Kolterman, J. Insel, M. Saekow, and J.M. Olefsky Mechanisms of insulin resistance in human obesity: evidence for receptor and postreceptor defects J. Clin. Investig. 65 1980 1272 1284
24. L.-X. Na, Y.-L. Zhang, Y. Li, L.-Y. Liu, R. Li, T. Kong, and et al. Curcumin improves insulin resistance in skeletal muscle of rats Nutr. Metab. Cardiovasc. Dis. NMCD 21 2011 526 533
25. M. Basaranoglu, G. Basaranoglu, T. Sabuncu, and H. Sentürk Fructose as a key player in the development of fatty liver disease World J. Gastroenterol. WJG 19 2013 1166 1172
26. J.S. Lim, M. Mietus-Snyder, A. Valente, J.-M. Schwarz, and R.H. Lustig The role of fructose in the pathogenesis of NAFLD and the metabolic syndrome Nat. Rev. Gastroenterol. Hepatol. 7 2010 251 264
27. A. Schultz, S. Barbosa-da-Silva, M.B. Aguila, and C.A. Mandarim-de-Lacerda Differences and similarities in hepatic lipogenesis, gluconeogenesis and oxidative imbalance in mice fed diets rich in fructose or sucrose Food Funct. 6 2015 1684 1691
28. N.M.K. Selvi Curcumin attenuates oxidative stress and activation of redox-sensitive kinases in high fructose- and high-fat-fed male wistar rats Sci. Pharm. 83 2015 10.3797/scipharm.1408-16
29. M.Y. Um, K.H. Hwang, J. Ahn, and T.Y. Ha Curcumin attenuates diet-induced hepatic steatosis by activating AMP-activated protein kinase Basic Clin. Pharmacol. Toxicol. 113 2013 152 157
30. E.E. Kershaw, and J.S. Flier Adipose tissue as an endocrine organ J. Clin. Endocrinol. Metab. 89 2004 2548 2556
31. G.S. Hotamisligil Inflammation and metabolic disorders Nature 444 2006 860 867
32. C.V.A.S.D. Balakrishnan Taurine supplementation attenuates erythrocyte lipid peroxidation in fructose-fed hypertensive rats Med. Sci. Res. 27 1999 489 492
33. S.P. Wolff, and R.T. Dean Glucose autoxidation and protein modification. The potential role of "autoxidative glycosylation" in diabetes Biochem. J. 245 1987 243 250
34. J.L. Rains, and S.K. Jain Oxidative stress, insulin signaling and diabetes Free Radic. Biol. Med. 50 2011 567 575
35. M.G. Sridhar, R. Vinayagamoorthi, V. Arul Suyambunathan, Z. Bobby, and N. Selvaraj Bitter gourd (Momordica charantia) improves insulin sensitivity by increasing skeletal muscle insulin-stimulated IRS-1 tyrosine phosphorylation in high-fat-fed rats Br. J. Nutr. 99 2008 806 812
36. A.T. Dinkova-Kostova, and P. Talalay Relation of structure of curcumin analogs to their potencies as inducers of Phase 2 detoxification enzymes Carcinogenesis 20 1999 911 914
37. S. Yamamoto, Y. Matsushita, T. Nakagawa, T. Hayashi, M. Noda, and T. Mizoue Circulating adiponectin levels and risk of type 2 diabetes in the Japanese Nutr. Diabetes 4 2014 e130
38. T.P. Combs, A.H. Berg, S. Obici, P.E. Scherer, and L. Rossetti Endogenous glucose production is inhibited by the adipose-derived protein Acrp30 J. Clin. Investig. 108 2001 1875 1881
39. S.P. Weisberg, R. Leibel, and D.V. Tortoriello Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity Endocrinology 149 2008 3549 3558
40. Y. He, Y. Yue, X. Zheng, K. Zhang, S. Chen, and Z. Du Curcumin, inflammation, and chronic diseases: how are they linked? Mol. Basel Switz. 20 2015 9183 9213
41. G. Kapakos, V. Youreva, and A.K. Srivastava Cardiovascular protection by curcumin: molecular aspects Indian J. Biochem. Biophys. 49 2012 306 315
42. W. Wongcharoen, and A. Phrommintikul The protective role of curcumin in cardiovascular diseases Int. J. Cardiol. 133 2009 145 151
43. J. Trujillo, Y.I. Chirino, E. Molina-Jijón, A.C. Andérica-Romero, E. Tapia, and J. Pedraza-Chaverrí Renoprotective effect of the antioxidant curcumin: recent findings Redox Biol. 1 2013 448 456