HIV-1 Vpr protein activates the NF-κB pathway to promote G2/M cell cycle arrest

Virologica Sinica

Volumn 30, Issue 6, 2015, Pages 441-448

  Liang, Zhibin ^a   Liu, Ruikang ^a,d   Lin, Yongquan ^a   Liang, Chen ^b,c   Tan, Juan ^a   Qiao, Wentao ^a  

^a NANKAI UNIVERSITY   (China)

^b MCGILL UNIVERSITY   (Canada)

^c MCGILL UNIVERSITY   (Canada)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

G2 M arrest; Human immunodeficiency virus type 1 (HIV 1); NF B; viral protein R (Vpr)

Indexed keywords

I KAPPA B KINASE ALPHA; I KAPPA B KINASE BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MUTANT PROTEIN; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR RELB; VPR PROTEIN; VPR PROTEIN, HUMAN IMMUNODEFICIENCY VIRUS 1;

ARTICLE; CONTROLLED STUDY; G2 PHASE CELL CYCLE CHECKPOINT; GENE SILENCING; HUMAN; HUMAN CELL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; CHEMISTRY; DNA REPLICATION; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HOST PATHOGEN INTERACTION; HUMAN IMMUNODEFICIENCY VIRUS 1; METABOLISM; MOLECULAR MODEL; MUTATION; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; REVERSE TRANSCRIPTION; RNA INTERFERENCE; TRANSCRIPTION INITIATION; VIRUS REPLICATION;

DNA REPLICATION; G2 PHASE CELL CYCLE CHECKPOINTS; HEK293 CELLS; HELA CELLS; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; MODELS, MOLECULAR; MUTATION; NF-KAPPA B; PROTEIN STRUCTURE, TERTIARY; REVERSE TRANSCRIPTION; RNA INTERFERENCE; TRANSCRIPTIONAL ACTIVATION; VIRUS REPLICATION; VPR GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS;

EID: 84952636638     PISSN: 16740769     EISSN: 1995820X     Source Type: Journal    
DOI: 10.1007/s12250-015-3654-8     Document Type: Article

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