Muscle-specific overexpression of PGC-1α does not augment metabolic improvements in response to exercise and caloric restriction

Diabetes

Volumn 64, Issue 5, 2015, Pages 1532-1543

  Wong, Kari E ^a   Mikus, Catherine R ^a   Slentz, Dorothy H ^a   Seiler, Sarah E ^a   Debalsi, Karen L ^a   Ilkayeva, Olga R ^a   Crain, Karen I ^b   Kinter, Michael T ^c   Kien, C Lawrence ^b,d   Stevens, Robert D ^a   Muoio, Deborah M ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF VERMONT COLLEGE OF MEDICINE   (United States)

^c Free Radical Biology and Aging Research Program   (United States)

^d UNIVERSITY OF VERMONT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CITRATE SYNTHASE; GLUCOSE; GLYCOGEN; INSULIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; FAT INTAKE; PPARGC1A PROTEIN, MOUSE; TRANSCRIPTION FACTOR;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CALORIC RESTRICTION; CITRIC ACID CYCLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENERGY BALANCE; ENERGY EXPENDITURE; ENERGY METABOLISM; EXERCISE TOLERANCE; FATTY ACID OXIDATION; GENE OVEREXPRESSION; GENOTYPE; GLUCOSE INTOLERANCE; GLUCOSE OXIDATION; GLUCOSE TOLERANCE; GLYCEMIC CONTROL; GLYCOGEN SYNTHESIS; INSULIN BLOOD LEVEL; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIFESTYLE MODIFICATION; LIPID DIET; LIPOTOXICITY; METABOLIC DISORDER; METABOLISM; MITOCHONDRIAL BIOGENESIS; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MOUSE; NONHUMAN; OBESITY; OXIDATION REDUCTION POTENTIAL; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; RESPIRATORY CHAIN; SKELETAL MUSCLE; TREADMILL EXERCISE; ADMINISTRATION AND DOSAGE; ADVERSE EFFECTS; ANIMAL; FAT INTAKE; GENE EXPRESSION REGULATION; GENETICS; MALE; MOTOR ACTIVITY; MUSCLE MITOCHONDRION; OXIDATION REDUCTION REACTION; PROTEOMICS;

ANIMALS; CALORIC RESTRICTION; DIETARY FATS; ENERGY METABOLISM; GENE EXPRESSION REGULATION; MALE; MICE; MITOCHONDRIA, MUSCLE; MOTOR ACTIVITY; MUSCLE, SKELETAL; OXIDATION-REDUCTION; PHYSICAL CONDITIONING, ANIMAL; PROTEOMICS; TRANSCRIPTION FACTORS;

EID: 84951943654     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db14-0827     Document Type: Article

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