Multiple functional variants in long-range enhancer elements contribute to the risk of SNP rs965513 in thyroid cancer

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 19, 2015, Pages 6128-6133

  He, Huiling ^a   Li, Wei ^a   Liyanarachchi, Sandya ^a   Srinivas, Mukund ^a   Wang, Yanqiang ^a   Akagi, Keiko ^a   Wang, Yao ^b   Wu, Dayong ^a   Wang, Qianben ^a   Jin, Victor ^b   Symer, David E ^a,c   Shen, Rulong ^c   Phay, John ^c   Nagy, Rebecca ^a,c   De La Chapelle, Albert ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c OHIO STATE UNIVERSITY   (United States)

Author keywords

Functional variants; Genetic susceptibility; Long range enhancer; SNP rs965513; Thyroid cancer

Indexed keywords

ADULT; ALLELE; ARTICLE; BINDING AFFINITY; CHROMATIN; CHROMOSOME; ENHANCER REGION; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; THYROID CANCER; THYROID CANCER CELL LINE; THYROID CARCINOMA; CARCINOMA; CHEMISTRY; CHROMATIN IMMUNOPRECIPITATION; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETICS; ODDS RATIO; PENETRANCE; THYROID TUMOR; TUMOR CELL LINE;

CHROMATIN; FORKHEAD TRANSCRIPTION FACTOR; FOXE1 PROTEIN, HUMAN; HISTONE;

ALLELES; CARCINOMA; CELL LINE, TUMOR; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; ENHANCER ELEMENTS, GENETIC; FORKHEAD TRANSCRIPTION FACTORS; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HAPLOTYPES; HISTONES; HUMANS; ODDS RATIO; PENETRANCE; POLYMORPHISM, SINGLE NUCLEOTIDE; THYROID NEOPLASMS;

EID: 84929206967     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1506255112     Document Type: Article

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