Bone marrow-derived mesenchymal stem cells assembled with low-dose BMP-2 in a three-dimensional hybrid construct enhances posterolateral spinal fusion in syngeneic rats

Spine Journal

Volumn 15, Issue 12, 2015, Pages 2552-2563

  Hu, Tao ^a   Abbah, Sunny Akogwu ^a   Toh, Soo Yein ^a   Wang, Ming ^a   Lam, Raymond Wing Moon ^a   Naidu, Mathanapriya ^a   Bhakta, Gajadhar ^b   Cool, Simon M ^a,b   Bhakoo, Kishore ^a,c   Li, Jun ^d   Goh, James Cho Hong ^a,d   Wong, Hee Kit ^a,e  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b INSTITUTE OF MEDICAL BIOLOGY   (Singapore)

^c AGENCY FOR SCIENCE   (Singapore)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^e University Orthopaedics   (Singapore)

Author keywords

Bone tissue engineering; Differentiation; Growth factor therapy; Hybrid construct; Stem cell; Undifferentiation

Indexed keywords

ASCORBIC ACID; CALCIUM PHOSPHATE; DEXAMETHASONE; GLYCEROL 2 PHOSPHATE; MESSENGER RNA; POLYCAPROLACTONE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2; RECOMBINANT PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BONE MARROW DERIVED MESENCHYMAL STEM CELL; BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; CONTROLLED STUDY; FISCHER 344 RAT; GENE EXPRESSION; HISTOPATHOLOGY; IN VITRO STUDY; IN VIVO STUDY; LOW DRUG DOSE; MESENCHYMAL STEM CELL TRANSPLANTATION; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSSIFICATION; POSTEROLATERAL SPINAL FUSION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RAT; REAL TIME POLYMERASE CHAIN REACTION; SPINE FUSION; ANIMAL; BONE DEVELOPMENT; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; HUMAN; MALE; MESENCHYMAL STROMA CELL; PROCEDURES; TISSUE ENGINEERING;

ANIMALS; BONE MORPHOGENETIC PROTEIN 2; CELLS, CULTURED; HUMANS; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; OSTEOGENESIS; RATS; RATS, INBRED F344; RECOMBINANT PROTEINS; SPINAL FUSION; TISSUE ENGINEERING; TRANSFORMING GROWTH FACTOR BETA;

EID: 84951728717     PISSN: 15299430     EISSN: 18781632     Source Type: Journal    
DOI: 10.1016/j.spinee.2015.08.063     Document Type: Article

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