Optimized bone regeneration based on sustained release from three-dimensional fibrous PLGA/HAp composite scaffolds loaded with BMP-2

Biotechnology and Bioengineering

Volumn 99, Issue 4, 2008, Pages 996-1006

  Fu, Yin Chih ^a   Nie, Hemin ^b   Ho, Mei Ling ^a   Wang, Chih Kuang ^c   Wang, Chi Hwa ^b  

^a KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Animal experiment; Bone morphogenetic protein 2; Electrospinning; Hydroxylapatite; Poly(D,L lactide co glycolide)

Indexed keywords

BIOCHEMICAL ENGINEERING; BIOMATERIALS; ELECTROSPINNING; FIBROUS MEMBRANES; ORTHOPEDICS; PROTEINS;

ANIMAL EXPERIMENTS; BONE MORPHOGENETIC PROTEIN; COMPOSITE SCAFFOLDS; HYDROXYLAPATITE;

SCAFFOLDS;

BONE MORPHOGENETIC PROTEIN 2; NANOPARTICLE; BONE MORPHOGENETIC PROTEIN; DRUG CARRIER; HYDROXYAPATITE; LACTIC ACID; POLYGLYCOLIC ACID; POLYLACTIC ACID POLYGLYCOLIC ACID COPOLYMER; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; POLYMER; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE GROWTH; BONE REGENERATION; CHEMICAL ANALYSIS; CONTROLLED STUDY; DRUG ACTIVITY; FRACTURE HEALING; HYPOTHESIS; IN VIVO STUDY; MORPHOLOGY; MOUSE; NONHUMAN; OSSIFICATION; PROTEIN BLOOD LEVEL; STAINING; STRENGTH; SUSTAINED DRUG RELEASE; X RAY; ANIMAL; BONE PROSTHESIS; CHEMISTRY; DELAYED RELEASE FORMULATION; DRUG EFFECT; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; TIBIA FRACTURE; TREATMENT OUTCOME;

ANIMALIA; MUS MUSCULUS;

ANIMALS; BONE MORPHOGENETIC PROTEINS; BONE REGENERATION; BONE SUBSTITUTES; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DURAPATITE; LACTIC ACID; MICE; MICE, NUDE; POLYGLYCOLIC ACID; POLYMERS; TIBIAL FRACTURES; TRANSFORMING GROWTH FACTOR BETA; TREATMENT OUTCOME;

EID: 39549119382     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.21648     Document Type: Article

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