Sequestration of rhBMP-2 into self-assembled polyelectrolyte complexes promotes anatomic localization of new bone in a porcine model of spinal reconstructive surgery

Tissue Engineering - Part A

Volumn 20, Issue 11-12, 2014, Pages 1679-1688

  Abbah, Sunny Akogwu ^a,b   Lam, Wing Moon Raymond ^a   Hu, Tao ^a   Goh, James ^a,c   Wong, Hee Kit ^a,c  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

DEFECTS; POLYELECTROLYTES; PROTEINS; TISSUE ENGINEERING;

BIOMECHANICAL STABILITY; BONE TISSUE ENGINEERING; COLLAGEN SPONGE; HETEROTOPIC OSSIFICATION; HUMAN BONE MORPHOGENETIC PROTEIN; LAYER BY LAYER SELF ASSEMBLY; POLYELECTROLYTE COMPLEXES; RECONSTRUCTIVE SURGERY;

BONE;

ALGINIC ACID; COLLAGEN SPONGE; HEPARIN; POLYELECTROLYTE; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; SELF ASSEMBLED MONOLAYER; BONE MORPHOGENETIC PROTEIN 2; ELECTROLYTE; GLUCURONIC ACID; HEXURONIC ACID; MICROSPHERE; RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2; RECOMBINANT PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANATOMICAL VARIATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BIORESORBABLE SCAFFOLD; BONE DEFECT; BONE MASS; BONE REGENERATION; BONE TISSUE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG RETENTION; DRUG SAFETY; DRUG UPTAKE; FRACTURE HEALING; GEL; HEALING IMPAIRMENT; HETEROTOPIC OSSIFICATION; HISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; INTRAMEDULLARY NAILING; MACROMOLECULE; MALE; MICRO-COMPUTED TOMOGRAPHY; NONHUMAN; OSSIFICATION; PRIORITY JOURNAL; PROTEIN IMMOBILIZATION; SPINAL RECONSTRUCTIVE SURGERY; SPINE FUSION; SPINE SURGERY; SURFACE CHARGE; TISSUE DISTRIBUTION; TISSUE ENGINEERING; TISSUE REACTION; WOUND HEALING; YORKSHIRE PIG; ZETA POTENTIAL; ANIMAL; BONE MINERALIZATION; DISEASE MODEL; DRUG EFFECTS; HUMAN; ORTHOPEDIC SURGERY; PATHOLOGY; PLASTIC SURGERY; RADIOGRAPHY; SPINE; SURGERY; SWINE; THREE DIMENSIONAL IMAGING;

ALGINATES; ANIMALS; BIOMECHANICAL PHENOMENA; BONE MORPHOGENETIC PROTEIN 2; CALCIFICATION, PHYSIOLOGIC; DISEASE MODELS, ANIMAL; ELECTROLYTES; GLUCURONIC ACID; HEXURONIC ACIDS; HUMANS; IMAGING, THREE-DIMENSIONAL; MALE; MICROSPHERES; ORTHOPEDIC PROCEDURES; OSSEOINTEGRATION; RECOMBINANT PROTEINS; RECONSTRUCTIVE SURGICAL PROCEDURES; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; SPINE; SUS SCROFA; TRANSFORMING GROWTH FACTOR BETA; X-RAY MICROTOMOGRAPHY;

EID: 84901196492     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2013.0593     Document Type: Article

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