Docetaxel (DTX)-loaded polydopamine-modified TPGS-PLA nanoparticles as a targeted drug delivery system for the treatment of liver cancer

Acta Biomaterialia

Volumn 30, Issue , 2016, Pages 144-154

  Zhu, Dunwan ^a   Tao, Wei ^b   Zhang, Hongling ^b,c   Liu, Gan ^b   Wang, Teng ^b   Zhang, Linhua ^a   Zeng, Xiaowei ^b   Mei, Lin ^b  

^a INSTITUTE OF BIOMEDICAL ENGINEERING   (China)

^b TSINGHUA UNIVERSITY   (China)

^c SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY   (China)

Author keywords

Cancer nanotechnology; Dopamine polymerization; Galactosylated nanoparticles; Liver targeting; Surface modification

Indexed keywords

CELL CULTURE; CELL MEMBRANES; CONTROLLED DRUG DELIVERY; DISEASES; GALACTOSAMINE; MOLECULAR BIOLOGY; NANOPARTICLES; POLYETHYLENE GLYCOLS; POLYMERIZATION; SURFACE TREATMENT; TARGETED DRUG DELIVERY; TUMORS;

CANCER NANOTECHNOLOGY; DOCETAXEL; DOPAMINE; DOPAMINE POLYMERIZATION; GALACTOSYLATED NANOPARTICLES; IN-VIVO; LIVER CANCER CELLS; LIVER TARGETING; POLYDOPAMINE; SURFACE-MODIFICATION;

LIGANDS;

DOCETAXEL; GALACTOSAMINE; GALACTOSAMINE D ALPHA TOCOPHEROL POKYETHYLENE GLYCOL 1000 SUCCINATE POLYLACTIDE NANOPARTICLE; NANOPARTICLE; POLYMER; UNCLASSIFIED DRUG; ALPHA TOCOPHEROL; ALPHA-TOCOPHERYL POLYETHYLENE GLYCOL SUCCINATE; INDOLE DERIVATIVE; LACTIC ACID; MACROGOL DERIVATIVE; POLYDOPAMINE; POLYLACTIC ACID; TAXOID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CANCER SIZE; CELL VIABILITY; CHEMICAL STRUCTURE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG FORMULATION; DRUG RELEASE; DRUG TARGETING; DRUG UPTAKE; ENDOCYTOSIS; FEMALE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; LIVER CANCER; MOUSE; NONHUMAN; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; SURFACE CHARGE; SURFACE PROPERTY; ZETA POTENTIAL; ANALOGS AND DERIVATIVES; ANIMAL; CARCINOMA, HEPATOCELLULAR; CHEMISTRY; DRUG SCREENING; HEPG2 CELL LINE; LIVER NEOPLASMS, EXPERIMENTAL; METABOLISM; NUDE MOUSE; PATHOLOGY; PROCEDURES;

ANIMALS; CARCINOMA, HEPATOCELLULAR; DRUG DELIVERY SYSTEMS; HEP G2 CELLS; HUMANS; INDOLES; LACTIC ACID; LIVER NEOPLASMS, EXPERIMENTAL; MICE; MICE, NUDE; NANOPARTICLES; POLYETHYLENE GLYCOLS; POLYMERS; TAXOIDS; VITAMIN E; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84951568546     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2015.11.031     Document Type: Article

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