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Volumn 45, Issue 11, 2015, Pages 3200-3203

Epigenetic analysis of regulatory T cells using multiplex bisulfite sequencing

Author keywords

Bisulfite sequencing; FOXP3; Methylation; Next generation sequencing; Regulatory T cell

Indexed keywords

TRANSCRIPTION FACTOR FOXP3; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, HUMAN; HYDROGEN SULFITE; SULFITE;

EID: 84951566738     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201545646     Document Type: Article
Times cited : (21)

References (14)
  • 1
    • 34548755672 scopus 로고    scopus 로고
    • DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells
    • Baron, U. DNA demethylation in the human FOXP3 locus discriminates regulatory T cells from activated FOXP3(+) conventional T cells. Eur. J. Immunol. 2007. 37: 2378-2389.
    • (2007) Eur. J. Immunol. , vol.37 , pp. 2378-2389
    • Baron, U.1
  • 2
    • 33846980131 scopus 로고    scopus 로고
    • Epigenetic control of the foxp3 locus in regulatory T cells
    • Floess, S. Epigenetic control of the foxp3 locus in regulatory T cells. PLoS Biol. 2007. 5: e38.
    • (2007) PLoS Biol. , vol.5 , pp. e38
    • Floess, S.1
  • 3
    • 66949171924 scopus 로고    scopus 로고
    • Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor
    • Miyara, M. Functional delineation and differentiation dynamics of human CD4+ T cells expressing the FoxP3 transcription factor. Immunity 2009. 30: 899-911.
    • (2009) Immunity , vol.30 , pp. 899-911
    • Miyara, M.1
  • 4
    • 84875458605 scopus 로고    scopus 로고
    • Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus
    • Toker, A. Active demethylation of the Foxp3 locus leads to the generation of stable regulatory T cells within the thymus. J. Immunol. 2013. 190: 3180-3188.
    • (2013) J. Immunol. , vol.190 , pp. 3180-3188
    • Toker, A.1
  • 5
    • 64049118001 scopus 로고    scopus 로고
    • Comparison of stable human Treg and Th clones by transcriptional profiling
    • Stockis, J. Comparison of stable human Treg and Th clones by transcriptional profiling. Eur. J. Immunol. 2009. 39: 869-882.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 869-882
    • Stockis, J.1
  • 6
    • 58349116249 scopus 로고    scopus 로고
    • Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue
    • Wieczorek, G. Quantitative DNA methylation analysis of FOXP3 as a new method for counting regulatory T cells in peripheral blood and solid tissue. Cancer Res. 2009. 69: 599-608.
    • (2009) Cancer Res. , vol.69 , pp. 599-608
    • Wieczorek, G.1
  • 7
    • 4544293301 scopus 로고    scopus 로고
    • Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates
    • Lewin, J. Quantitative DNA methylation analysis based on four-dye trace data from direct sequencing of PCR amplificates. Bioinformatics 2004. 20: 3005-3012.
    • (2004) Bioinformatics , vol.20 , pp. 3005-3012
    • Lewin, J.1
  • 8
    • 84919606611 scopus 로고    scopus 로고
    • A sensitive protocol for FOXP3 epigenetic analysis in scarce human samples
    • Spreafico, R. A sensitive protocol for FOXP3 epigenetic analysis in scarce human samples. Eur. J. Immunol. 2014. 44: 3141-3143.
    • (2014) Eur. J. Immunol. , vol.44 , pp. 3141-3143
    • Spreafico, R.1
  • 9
    • 84869148187 scopus 로고    scopus 로고
    • T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development
    • Ohkura, N. T cell receptor stimulation-induced epigenetic changes and Foxp3 expression are independent and complementary events required for Treg cell development. Immunity 2012. 37: 785-799.
    • (2012) Immunity , vol.37 , pp. 785-799
    • Ohkura, N.1
  • 10
    • 34447265236 scopus 로고    scopus 로고
    • CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation
    • Kim, H. P. CREB/ATF-dependent T cell receptor-induced FoxP3 gene expression: a role for DNA methylation. J. Exp. Med. 2007. 204: 1543-1551.
    • (2007) J. Exp. Med. , vol.204 , pp. 1543-1551
    • Kim, H.P.1
  • 11
    • 33745817085 scopus 로고    scopus 로고
    • CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells
    • Liu, W. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. J. Exp. Med. 2006. 203: 1701-1711.
    • (2006) J. Exp. Med. , vol.203 , pp. 1701-1711
    • Liu, W.1
  • 12
    • 84907070734 scopus 로고    scopus 로고
    • hi T cells is decoupled from FOXP3 expression at the inflamed site in childhood arthritis
    • hi T cells is decoupled from FOXP3 expression at the inflamed site in childhood arthritis. J. Immunol. 2014. 193: 2699-2708.
    • (2014) J. Immunol. , vol.193 , pp. 2699-2708
    • Bending, D.1
  • 13
    • 79955028001 scopus 로고    scopus 로고
    • Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes
    • McClymont, S. A. Plasticity of human regulatory T cells in healthy subjects and patients with type 1 diabetes. J. Immunol. 2011. 186: 3918-3926.
    • (2011) J. Immunol. , vol.186 , pp. 3918-3926
    • McClymont, S.A.1
  • 14
    • 84891332899 scopus 로고    scopus 로고
    • Genome-wide methylation analyses of primary human leukocyte subsets identifies functionally important cell-type specific hypomethylated regions
    • Zilbauer, M. Genome-wide methylation analyses of primary human leukocyte subsets identifies functionally important cell-type specific hypomethylated regions. Blood 2013. 122: e52-e60.
    • (2013) Blood , vol.122 , pp. e52-e60
    • Zilbauer, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.