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Volumn 126, Issue 24, 2015, Pages 2561-2569

From cytopenia to leukemia: The role of Gfi1 and Gfi1b in blood formation

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GFI1; TRANSCRIPTION FACTOR GFI1B; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; GFI1 PROTEIN, HUMAN; GFI1 PROTEIN, MOUSE; GFI1B PROTEIN, HUMAN; ONCOPROTEIN; REPRESSOR PROTEIN;

EID: 84951320159     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2015-06-655043     Document Type: Review
Times cited : (85)

References (88)
  • 1
    • 0027462484 scopus 로고
    • Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein
    • Gilks CB, Bear SE, Grimes HL, Tsichlis PN. Progression of interleukin-2 (IL-2)-dependent rat T cell lymphoma lines to IL-2-independent growth following activation of a gene (Gfi-1) encoding a novel zinc finger protein. Mol Cell Biol. 1993;13(3): 1759-1768.
    • (1993) Mol Cell Biol , vol.13 , Issue.3 , pp. 1759-1768
    • Gilks, C.B.1    Bear, S.E.2    Grimes, H.L.3    Tsichlis, P.N.4
  • 2
    • 0029991422 scopus 로고    scopus 로고
    • Zinc finger protein GFI-1 cooperates with myc and pim-1 in T-cell lymphomagenesis by reducing the requirements for IL-2
    • Zörnig M, Schmidt T, Karsunky H, Grzeschiczek A, Möröy T. Zinc finger protein GFI-1 cooperates with myc and pim-1 in T-cell lymphomagenesis by reducing the requirements for IL-2. Oncogene. 1996;12(8):1789-1801.
    • (1996) Oncogene , vol.12 , Issue.8 , pp. 1789-1801
    • Zörnig, M.1    Schmidt, T.2    Karsunky, H.3    Grzeschiczek, A.4    Möröy, T.5
  • 3
    • 0031060318 scopus 로고    scopus 로고
    • Characterization of pal-1, a common proviral insertion site in murine leukemia virus-induced lymphomas of c-myc and Pim-1 transgenic mice
    • Scheijen B, Jonkers J, Acton D, Berns A. Characterization of pal-1, a common proviral insertion site in murine leukemia virus-induced lymphomas of c-myc and Pim-1 transgenic mice. J Virol. 1997;71(1):9-16.
    • (1997) J Virol , vol.71 , Issue.1 , pp. 9-16
    • Scheijen, B.1    Jonkers, J.2    Acton, D.3    Berns, A.4
  • 4
    • 0031895515 scopus 로고    scopus 로고
    • The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation
    • Tong B, Grimes HL, Yang TY, et al. The Gfi-1B proto-oncoprotein represses p21WAF1 and inhibits myeloid cell differentiation. Mol Cell Biol. 1998;18(5):2462-2473.
    • (1998) Mol Cell Biol , vol.18 , Issue.5 , pp. 2462-2473
    • Tong, B.1    Grimes, H.L.2    Yang, T.Y.3
  • 5
    • 0032535164 scopus 로고    scopus 로고
    • The human homologue (GFI1B) of the chicken GFI gene maps to chromosome 9q34.13-A locus frequently altered in hematopoietic diseases
    • Rödel B, Wagner T, Zörnig M, Niessing J, Möröy T. The human homologue (GFI1B) of the chicken GFI gene maps to chromosome 9q34.13-A locus frequently altered in hematopoietic diseases. Genomics. 1998;54(3):580-582.
    • (1998) Genomics , vol.54 , Issue.3 , pp. 580-582
    • Rödel, B.1    Wagner, T.2    Zörnig, M.3    Niessing, J.4    Möröy, T.5
  • 6
    • 0029883328 scopus 로고    scopus 로고
    • MoMuLV proviral integrations identified by Sup-F selection in tumors from infected myc/pim bitransgenic mice correlate with activation of the gfi-1 gene
    • Schmidt T, Zörnig M, Beneke R, Möröy T. MoMuLV proviral integrations identified by Sup-F selection in tumors from infected myc/pim bitransgenic mice correlate with activation of the gfi-1 gene. Nucleic Acids Res. 1996;24(13): 2528-2534.
    • (1996) Nucleic Acids Res , vol.24 , Issue.13 , pp. 2528-2534
    • Schmidt, T.1    Zörnig, M.2    Beneke, R.3    Möröy, T.4
  • 7
    • 0029806268 scopus 로고    scopus 로고
    • The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal
    • Grimes HL, Chan TO, Zweidler-McKay PA, Tong B, Tsichlis PN. The Gfi-1 proto-oncoprotein contains a novel transcriptional repressor domain, SNAG, and inhibits G1 arrest induced by interleukin-2 withdrawal. Mol Cell Biol. 1996; 16(11):6263-6272.
    • (1996) Mol Cell Biol , vol.16 , Issue.11 , pp. 6263-6272
    • Grimes, H.L.1    Chan, T.O.2    Zweidler-McKay, P.A.3    Tong, B.4    Tsichlis, P.N.5
  • 8
    • 0029897536 scopus 로고    scopus 로고
    • Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor
    • Zweidler-Mckay PA, Grimes HL, Flubacher MM, Tsichlis PN. Gfi-1 encodes a nuclear zinc finger protein that binds DNA and functions as a transcriptional repressor. Mol Cell Biol. 1996; 16(8):4024-4034.
    • (1996) Mol Cell Biol , vol.16 , Issue.8 , pp. 4024-4034
    • Zweidler-Mckay, P.A.1    Grimes, H.L.2    Flubacher, M.M.3    Tsichlis, P.N.4
  • 9
    • 33745061315 scopus 로고    scopus 로고
    • Senseless physically interacts with proneural proteins and functions as a transcriptional co-activator
    • Acar M, Jafar-Nejad H, Giagtzoglou N, et al. Senseless physically interacts with proneural proteins and functions as a transcriptional co-activator. Development. 2006;133(10):1979-1989.
    • (2006) Development , vol.133 , Issue.10 , pp. 1979-1989
    • Acar, M.1    Jafar-Nejad, H.2    Giagtzoglou, N.3
  • 10
    • 14044276343 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t(14;18) lymphomas
    • Duan H, Heckman CA, Boxer LM. Histone deacetylase inhibitors down-regulate bcl-2 expression and induce apoptosis in t(14;18) lymphomas. Mol Cell Biol. 2005;25(5): 1608-1619.
    • (2005) Mol Cell Biol , vol.25 , Issue.5 , pp. 1608-1619
    • Duan, H.1    Heckman, C.A.2    Boxer, L.M.3
  • 11
    • 0042769321 scopus 로고    scopus 로고
    • Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism
    • McGhee L, Bryan J, Elliott L, et al. Gfi-1 attaches to the nuclear matrix, associates with ETO (MTG8) and histone deacetylase proteins, and represses transcription using a TSA-sensitive mechanism. J Cell Biochem. 2003;89(5): 1005-1018.
    • (2003) J Cell Biochem , vol.89 , Issue.5 , pp. 1005-1018
    • McGhee, L.1    Bryan, J.2    Elliott, L.3
  • 12
    • 33745756792 scopus 로고    scopus 로고
    • Gfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromatin
    • Vassen L, Fiolka K, Möröy T. Gfi1b alters histone methylation at target gene promoters and sites of gamma-satellite containing heterochromatin. EMBO J. 2006;25(11):2409-2419.
    • (2006) EMBO J , vol.25 , Issue.11 , pp. 2409-2419
    • Vassen, L.1    Fiolka, K.2    Möröy, T.3
  • 13
    • 33645766023 scopus 로고    scopus 로고
    • Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development
    • Fiolka K, Hertzano R, Vassen L, et al. Gfi1 and Gfi1b act equivalently in haematopoiesis, but have distinct, non-overlapping functions in inner ear development. EMBO Rep. 2006;7(3): 326-333.
    • (2006) EMBO Rep , vol.7 , Issue.3 , pp. 326-333
    • Fiolka, K.1    Hertzano, R.2    Vassen, L.3
  • 14
    • 57649115445 scopus 로고    scopus 로고
    • Ajuba functions as a histone deacetylasedependent co-repressor for autoregulation of the growth factor-independent-1 transcription factor
    • Montoya-Durango DE, Velu CS, Kazanjian A, et al. Ajuba functions as a histone deacetylasedependent co-repressor for autoregulation of the growth factor-independent-1 transcription factor. J Biol Chem. 2008;283(46):32056-32065.
    • (2008) J Biol Chem , vol.283 , Issue.46 , pp. 32056-32065
    • Montoya-Durango, D.E.1    Velu, C.S.2    Kazanjian, A.3
  • 15
    • 43249086048 scopus 로고    scopus 로고
    • The LIM protein AJUBA recruits protein arginine methyltransferase 5 to mediate SNAIL-dependent transcriptional repression
    • Hou Z, Peng H, Ayyanathan K, et al. The LIM protein AJUBA recruits protein arginine methyltransferase 5 to mediate SNAIL-dependent transcriptional repression. Mol Cell Biol. 2008; 28(10):3198-3207.
    • (2008) Mol Cell Biol , vol.28 , Issue.10 , pp. 3198-3207
    • Hou, Z.1    Peng, H.2    Ayyanathan, K.3
  • 16
    • 82555164922 scopus 로고    scopus 로고
    • Growth factor independence 1 (Gfi1) as a regulator of lymphocyte development and activation
    • Möröy T, Khandanpour C. Growth factor independence 1 (Gfi1) as a regulator of lymphocyte development and activation. Semin Immunol. 2011;23(5):368-378.
    • (2011) Semin Immunol , vol.23 , Issue.5 , pp. 368-378
    • Möröy, T.1    Khandanpour, C.2
  • 17
    • 77954071946 scopus 로고    scopus 로고
    • Gfi1-cells and circuits: Unraveling transcriptional networks of development and disease
    • Phelan JD, Shroyer NF, Cook T, Gebelein B, Grimes HL. Gfi1-cells and circuits: unraveling transcriptional networks of development and disease. Curr Opin Hematol. 2010;17(4):300-307.
    • (2010) Curr Opin Hematol , vol.17 , Issue.4 , pp. 300-307
    • Phelan, J.D.1    Shroyer, N.F.2    Cook, T.3    Gebelein, B.4    Grimes, H.L.5
  • 19
    • 13244252714 scopus 로고    scopus 로고
    • Gfi-1 takes center stage in hematopoietic stem cells
    • Duan Z, Horwitz M. Gfi-1 takes center stage in hematopoietic stem cells. Trends Mol Med. 2005; 11(2):49-52.
    • (2005) Trends Mol Med , vol.11 , Issue.2 , pp. 49-52
    • Duan, Z.1    Horwitz, M.2
  • 20
    • 12744279206 scopus 로고    scopus 로고
    • Gfi-1: Another piece in the HSC puzzle
    • Cellot S, Sauvageau G. Gfi-1: another piece in the HSC puzzle. Trends Immunol. 2005;26(2):68-71.
    • (2005) Trends Immunol , vol.26 , Issue.2 , pp. 68-71
    • Cellot, S.1    Sauvageau, G.2
  • 21
    • 11144322855 scopus 로고    scopus 로고
    • The zinc finger transcription factor growth factor independence 1 (Gfi1)
    • Möröy T. The zinc finger transcription factor growth factor independence 1 (Gfi1). Int J Biochem Cell Biol. 2005;37(3):541-546.
    • (2005) Int J Biochem Cell Biol , vol.37 , Issue.3 , pp. 541-546
    • Möröy, T.1
  • 22
    • 33746195568 scopus 로고    scopus 로고
    • The growth factor independence-1 transcription factor: New functions and new insights
    • Kazanjian A, Gross EA, Grimes HL. The growth factor independence-1 transcription factor: new functions and new insights. Crit Rev Oncol Hematol. 2006;59(2):85-97.
    • (2006) Crit Rev Oncol Hematol , vol.59 , Issue.2 , pp. 85-97
    • Kazanjian, A.1    Gross, E.A.2    Grimes, H.L.3
  • 23
    • 0142180052 scopus 로고    scopus 로고
    • Gfi-1 oncoproteins in hematopoiesis
    • Duan Z, Horwitz M. Gfi-1 oncoproteins in hematopoiesis. Hematology. 2003;8(5):339-344.
    • (2003) Hematology , vol.8 , Issue.5 , pp. 339-344
    • Duan, Z.1    Horwitz, M.2
  • 24
    • 33644843788 scopus 로고    scopus 로고
    • Zinc-finger transcription factor Gfi-1: Versatile regulator of lymphocytes, neutrophils and hematopoietic stem cells
    • Hock H, Orkin SH. Zinc-finger transcription factor Gfi-1: versatile regulator of lymphocytes, neutrophils and hematopoietic stem cells. Curr Opin Hematol. 2006;13(1):1-6.
    • (2006) Curr Opin Hematol , vol.13 , Issue.1 , pp. 1-6
    • Hock, H.1    Orkin, S.H.2
  • 25
    • 4644272644 scopus 로고    scopus 로고
    • Gfi1:green fluorescent protein knock-in mutant reveals differential expression and autoregulation of the growth factor independence 1 (Gfi1) gene during lymphocyte development
    • Yücel R, Kosan C, Heyd F, Möröy T. Gfi1:green fluorescent protein knock-in mutant reveals differential expression and autoregulation of the growth factor independence 1 (Gfi1) gene during lymphocyte development. J Biol Chem. 2004;279(39):40906-40917.
    • (2004) J Biol Chem , vol.279 , Issue.39 , pp. 40906-40917
    • Yücel, R.1    Kosan, C.2    Heyd, F.3    Möröy, T.4
  • 26
    • 33947251378 scopus 로고    scopus 로고
    • Gfi1b:green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1
    • Vassen L, Okayama T, Möröy T. Gfi1b:green fluorescent protein knock-in mice reveal a dynamic expression pattern of Gfi1b during hematopoiesis that is largely complementary to Gfi1. Blood. 2007;109(6):2356-2364.
    • (2007) Blood , vol.109 , Issue.6 , pp. 2356-2364
    • Vassen, L.1    Okayama, T.2    Möröy, T.3
  • 27
    • 8144220648 scopus 로고    scopus 로고
    • Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells
    • Zeng H, Yücel R, Kosan C, Klein-Hitpass L, Möröy T. Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells. EMBO J. 2004;23(20):4116-4125.
    • (2004) EMBO J , vol.23 , Issue.20 , pp. 4116-4125
    • Zeng, H.1    Yücel, R.2    Kosan, C.3    Klein-Hitpass, L.4    Möröy, T.5
  • 28
    • 7244231429 scopus 로고    scopus 로고
    • Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells
    • Hock H, Hamblen MJ, Rooke HM, et al. Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells. Nature. 2004;431(7011):1002-1007.
    • (2004) Nature , vol.431 , Issue.7011 , pp. 1002-1007
    • Hock, H.1    Hamblen, M.J.2    Rooke, H.M.3
  • 29
    • 78650049003 scopus 로고    scopus 로고
    • Evidence that growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells
    • Khandanpour C, Sharif-Askari E, Vassen L, et al. Evidence that growth factor independence 1b regulates dormancy and peripheral blood mobilization of hematopoietic stem cells. Blood. 2010;116(24):5149-5161.
    • (2010) Blood , vol.116 , Issue.24 , pp. 5149-5161
    • Khandanpour, C.1    Sharif-Askari, E.2    Vassen, L.3
  • 30
    • 0032547947 scopus 로고    scopus 로고
    • Zinc finger protein GFI-1 has low oncogenic potential but cooperates strongly with pim and myc genes in T-cell lymphomagenesis
    • Schmidt T, Karsunky H, Gau E, Zevnik B, Elsässer HP, Möröy T. Zinc finger protein GFI-1 has low oncogenic potential but cooperates strongly with pim and myc genes in T-cell lymphomagenesis. Oncogene. 1998;17(20): 2661-2667.
    • (1998) Oncogene , vol.17 , Issue.20 , pp. 2661-2667
    • Schmidt, T.1    Karsunky, H.2    Gau, E.3    Zevnik, B.4    Elsässer, H.P.5    Möröy, T.6
  • 31
    • 0032531041 scopus 로고    scopus 로고
    • Evidence implicating Gfi-1 and Pim-1 in pre-T-cell differentiation steps associated with beta-selection
    • Schmidt T, Karsunky H, Rödel B, Zevnik B, Elsässer HP, Möröy T. Evidence implicating Gfi-1 and Pim-1 in pre-T-cell differentiation steps associated with beta-selection. EMBO J. 1998; 17(18):5349-5359.
    • (1998) EMBO J , vol.17 , Issue.18 , pp. 5349-5359
    • Schmidt, T.1    Karsunky, H.2    Rödel, B.3    Zevnik, B.4    Elsässer, H.P.5    Möröy, T.6
  • 32
    • 84900540969 scopus 로고    scopus 로고
    • Growth factor independence 1b (gfi1b) is important for the maturation of erythroid cells and the regulation of embryonic globin expression
    • Vassen L, Beauchemin H, Lemsaddek W, Krongold J, Trudel M, Möröy T. Growth factor independence 1b (gfi1b) is important for the maturation of erythroid cells and the regulation of embryonic globin expression. PLoS One. 2014; 9(5):e96636.
    • (2014) PLoS One , vol.9 , Issue.5 , pp. e96636
    • Vassen, L.1    Beauchemin, H.2    Lemsaddek, W.3    Krongold, J.4    Trudel, M.5    Möröy, T.6
  • 33
    • 84907056140 scopus 로고    scopus 로고
    • Gfi-1 regulates the erythroid transcription factor network through Id2 repression in murine hematopoietic progenitor cells
    • Kim W, Klarmann KD, Keller JR. Gfi-1 regulates the erythroid transcription factor network through Id2 repression in murine hematopoietic progenitor cells. Blood. 2014; 124(10):1586-1596.
    • (2014) Blood , vol.124 , Issue.10 , pp. 1586-1596
    • Kim, W.1    Klarmann, K.D.2    Keller, J.R.3
  • 34
    • 58149345673 scopus 로고    scopus 로고
    • The zinc finger protein Gfi1 is implicated in the regulation of IgG2b production and the expression of Igamma2b germline transcripts
    • Igwe E, Kosan C, Khandanpour C, Sharif-Askari E, Brüne B, Möröy T. The zinc finger protein Gfi1 is implicated in the regulation of IgG2b production and the expression of Igamma2b germline transcripts. Eur J Immunol. 2008;38(11): 3004-3014.
    • (2008) Eur J Immunol , vol.38 , Issue.11 , pp. 3004-3014
    • Igwe, E.1    Kosan, C.2    Khandanpour, C.3    Sharif-Askari, E.4    Brüne, B.5    Möröy, T.6
  • 35
    • 70349728484 scopus 로고    scopus 로고
    • A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates
    • Spooner CJ, Cheng JX, Pujadas E, Laslo P, Singh H. A recurrent network involving the transcription factors PU.1 and Gfi1 orchestrates innate and adaptive immune cell fates. Immunity. 2009;31(4):576-586.
    • (2009) Immunity , vol.31 , Issue.4 , pp. 576-586
    • Spooner, C.J.1    Cheng, J.X.2    Pujadas, E.3    Laslo, P.4    Singh, H.5
  • 36
    • 84888000653 scopus 로고    scopus 로고
    • Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1
    • Spooner CJ, Lesch J, Yan D, et al. Specification of type 2 innate lymphocytes by the transcriptional determinant Gfi1. Nat Immunol. 2013;14(12): 1229-1236.
    • (2013) Nat Immunol , vol.14 , Issue.12 , pp. 1229-1236
    • Spooner, C.J.1    Lesch, J.2    Yan, D.3
  • 37
    • 33845285520 scopus 로고    scopus 로고
    • Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion
    • Zhu J, Jankovic D, Grinberg A, Guo L, Paul WE. Gfi-1 plays an important role in IL-2-mediated Th2 cell expansion. Proc Natl Acad Sci USA. 2006; 103(48):18214-18219.
    • (2006) Proc Natl Acad Sci USA , vol.103 , Issue.48 , pp. 18214-18219
    • Zhu, J.1    Jankovic, D.2    Grinberg, A.3    Guo, L.4    Paul, W.E.5
  • 38
    • 20444466497 scopus 로고    scopus 로고
    • The transcriptional repressor Gfi1 controls STAT3-dependent dendritic cell development and function
    • Rathinam C, Geffers R, Yücel R, et al. The transcriptional repressor Gfi1 controls STAT3-dependent dendritic cell development and function. Immunity. 2005;22(6): 717-728.
    • (2005) Immunity , vol.22 , Issue.6 , pp. 717-728
    • Rathinam, C.1    Geffers, R.2    Yücel, R.3
  • 39
    • 84884535466 scopus 로고    scopus 로고
    • Gfi1 and gfi1b repress rag transcription in plasmacytoid dendritic cells in vitro
    • Chow KT, Schulz D, McWhirter SM, Schlissel MS. Gfi1 and gfi1b repress rag transcription in plasmacytoid dendritic cells in vitro. PLoS One. 2013;8(9):e75891.
    • (2013) PLoS One , vol.8 , Issue.9 , pp. e75891
    • Chow, K.T.1    Schulz, D.2    McWhirter, S.M.3    Schlissel, M.S.4
  • 40
    • 84868609113 scopus 로고    scopus 로고
    • The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice
    • Khandanpour C, Krongold J, Schütte J, et al. The human GFI136N variant induces epigenetic changes at the Hoxa9 locus and accelerates K-RAS driven myeloproliferative disorder in mice. Blood. 2012;120(19):4006-4017.
    • (2012) Blood , vol.120 , Issue.19 , pp. 4006-4017
    • Khandanpour, C.1    Krongold, J.2    Schütte, J.3
  • 41
    • 67049108074 scopus 로고    scopus 로고
    • Gfi1 integrates progenitor versus granulocytic transcriptional programming
    • Horman SR, Velu CS, Chaubey A, et al. Gfi1 integrates progenitor versus granulocytic transcriptional programming. Blood. 2009; 113(22):5466-5475.
    • (2009) Blood , vol.113 , Issue.22 , pp. 5466-5475
    • Horman, S.R.1    Velu, C.S.2    Chaubey, A.3
  • 42
    • 34249714440 scopus 로고    scopus 로고
    • The transcriptional repressor GFI-1 antagonizes PU.1 activity through proteinprotein interaction
    • Dahl R, Iyer SR, Owens KS, Cuylear DD, Simon MC. The transcriptional repressor GFI-1 antagonizes PU.1 activity through proteinprotein interaction. J Biol Chem. 2007;282(9): 6473-6483.
    • (2007) J Biol Chem , vol.282 , Issue.9 , pp. 6473-6483
    • Dahl, R.1    Iyer, S.R.2    Owens, K.S.3    Cuylear, D.D.4    Simon, M.C.5
  • 43
    • 77957348625 scopus 로고    scopus 로고
    • Combinatorial transcriptional control in blood stem/progenitor cells: Genome-wide analysis of ten major transcriptional regulators
    • Wilson NK, Foster SD, Wang X, et al. Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators. Cell Stem Cell. 2010;7(4):532-544.
    • (2010) Cell Stem Cell , vol.7 , Issue.4 , pp. 532-544
    • Wilson, N.K.1    Foster, S.D.2    Wang, X.3
  • 44
    • 0037127270 scopus 로고    scopus 로고
    • Regulation of Socs gene expression by the proto-oncoprotein GFI-1B: Two routes for STAT5 target gene induction by erythropoietin
    • Jegalian AG, Wu H. Regulation of Socs gene expression by the proto-oncoprotein GFI-1B: two routes for STAT5 target gene induction by erythropoietin. J Biol Chem. 2002;277(3): 2345-2352.
    • (2002) J Biol Chem , vol.277 , Issue.3 , pp. 2345-2352
    • Jegalian, A.G.1    Wu, H.2
  • 45
    • 0037371433 scopus 로고    scopus 로고
    • Growth factor independence-1B expression leads to defects in T cell activation, IL-7 receptor alpha expression, and T cell lineage commitment
    • Doan LL, Kitay MK, Yu Q, et al. Growth factor independence-1B expression leads to defects in T cell activation, IL-7 receptor alpha expression, and T cell lineage commitment. J Immunol. 2003; 170(5):2356-2366.
    • (2003) J Immunol , vol.170 , Issue.5 , pp. 2356-2366
    • Doan, L.L.1    Kitay, M.K.2    Yu, Q.3
  • 46
    • 34248366579 scopus 로고    scopus 로고
    • Growth factor independent 1B (Gfi1b) is an E2A target gene that modulates Gata3 in T-cell lymphomas
    • Xu W, Kee BL. Growth factor independent 1B (Gfi1b) is an E2A target gene that modulates Gata3 in T-cell lymphomas. Blood. 2007;109(10): 4406-4414.
    • (2007) Blood , vol.109 , Issue.10 , pp. 4406-4414
    • Xu, W.1    Kee, B.L.2
  • 47
    • 34250163897 scopus 로고    scopus 로고
    • GATA-1 and Gfi-1B interplay to regulate Bcl-xL transcription
    • Kuo YY, Chang ZF. GATA-1 and Gfi-1B interplay to regulate Bcl-xL transcription. Mol Cell Biol. 2007;27(12):4261-4272.
    • (2007) Mol Cell Biol , vol.27 , Issue.12 , pp. 4261-4272
    • Kuo, Y.Y.1    Chang, Z.F.2
  • 48
    • 84872155381 scopus 로고    scopus 로고
    • Differential transcriptional regulation of meis1 by Gfi1b and its co-factors LSD1 and CoREST
    • Chowdhury AH, Ramroop JR, Upadhyay G, Sengupta A, Andrzejczyk A, Saleque S. Differential transcriptional regulation of meis1 by Gfi1b and its co-factors LSD1 and CoREST. PLoS One. 2013;8(1):e53666.
    • (2013) PLoS One , vol.8 , Issue.1 , pp. e53666
    • Chowdhury, A.H.1    Ramroop, J.R.2    Upadhyay, G.3    Sengupta, A.4    Andrzejczyk, A.5    Saleque, S.6
  • 49
    • 84876471008 scopus 로고    scopus 로고
    • Characterization of transcriptional networks in blood stem and progenitor cells using highthroughput single-cell gene expression analysis
    • Moignard V, Macaulay IC, Swiers G, et al. Characterization of transcriptional networks in blood stem and progenitor cells using highthroughput single-cell gene expression analysis. Nat Cell Biol. 2013;15(4):363-372.
    • (2013) Nat Cell Biol , vol.15 , Issue.4 , pp. 363-372
    • Moignard, V.1    Macaulay, I.C.2    Swiers, G.3
  • 50
    • 84856940026 scopus 로고    scopus 로고
    • Gfi1b negatively regulates Rag expression directly and via the repression of FoxO1
    • Schulz D, Vassen L, Chow KT, et al. Gfi1b negatively regulates Rag expression directly and via the repression of FoxO1. J Exp Med. 2012; 209(1):187-199.
    • (2012) J Exp Med , vol.209 , Issue.1 , pp. 187-199
    • Schulz, D.1    Vassen, L.2    Chow, K.T.3
  • 51
    • 84904816744 scopus 로고    scopus 로고
    • Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
    • Northcott PA, Lee C, Zichner T, et al. Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma. Nature. 2014;511(7510): 428-434.
    • (2014) Nature , vol.511 , Issue.7510 , pp. 428-434
    • Northcott, P.A.1    Lee, C.2    Zichner, T.3
  • 52
    • 84873595634 scopus 로고    scopus 로고
    • Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia
    • Khandanpour C, Phelan JD, Vassen L, et al. Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia. Cancer Cell. 2013;23(2): 200-214.
    • (2013) Cancer Cell , vol.23 , Issue.2 , pp. 200-214
    • Khandanpour, C.1    Phelan, J.D.2    Vassen, L.3
  • 53
    • 84884694957 scopus 로고    scopus 로고
    • Growth factor independent-1 maintains Notch1- dependent transcriptional programming of lymphoid precursors
    • Phelan JD, Saba I, Zeng H, et al. Growth factor independent-1 maintains Notch1- dependent transcriptional programming of lymphoid precursors. PLoS Genet. 2013;9(9): e1003713.
    • (2013) PLoS Genet , vol.9 , Issue.9 , pp. e1003713
    • Phelan, J.D.1    Saba, I.2    Zeng, H.3
  • 54
    • 84900559529 scopus 로고    scopus 로고
    • Growth factor independence 1 (Gfi1) regulates cell-fate decision of a bipotential granulocytic-monocytic precursor defined by expression of Gfi1 and CD48
    • Vassen L, Dührsen U, Kosan C, Zeng H, Möröy T. Growth factor independence 1 (Gfi1) regulates cell-fate decision of a bipotential granulocytic-monocytic precursor defined by expression of Gfi1 and CD48. Am J Blood Res. 2012;2(4):228-242.
    • (2012) Am J Blood Res , vol.2 , Issue.4 , pp. 228-242
    • Vassen, L.1    Dührsen, U.2    Kosan, C.3    Zeng, H.4    Möröy, T.5
  • 55
    • 84899709023 scopus 로고    scopus 로고
    • Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation
    • Foudi A, Kramer DJ, Qin J, et al. Distinct, strict requirements for Gfi-1b in adult bone marrow red cell and platelet generation. J Exp Med. 2014; 211(5):909-927.
    • (2014) J Exp Med , vol.211 , Issue.5 , pp. 909-927
    • Foudi, A.1    Kramer, D.J.2    Qin, J.3
  • 56
    • 79952138371 scopus 로고    scopus 로고
    • Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease
    • Khandanpour C, Kosan C, Gaudreau MC, et al. Growth factor independence 1 protects hematopoietic stem cells against apoptosis but also prevents the development of a myeloproliferative-like disease. Stem Cells. 2011; 29(2):376-385.
    • (2011) Stem Cells , vol.29 , Issue.2 , pp. 376-385
    • Khandanpour, C.1    Kosan, C.2    Gaudreau, M.C.3
  • 57
    • 50849139175 scopus 로고    scopus 로고
    • Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system
    • Laslo P, Pongubala JM, Lancki DW, Singh H. Gene regulatory networks directing myeloid and lymphoid cell fates within the immune system. Semin Immunol. 2008;20(4): 228-235.
    • (2008) Semin Immunol , vol.20 , Issue.4 , pp. 228-235
    • Laslo, P.1    Pongubala, J.M.2    Lancki, D.W.3    Singh, H.4
  • 58
    • 33747196725 scopus 로고    scopus 로고
    • Multilineage transcriptional priming and determination of alternate hematopoietic cell fates
    • Laslo P, Spooner CJ, Warmflash A, et al. Multilineage transcriptional priming and determination of alternate hematopoietic cell fates. Cell. 2006;126(4):755-766.
    • (2006) Cell , vol.126 , Issue.4 , pp. 755-766
    • Laslo, P.1    Spooner, C.J.2    Warmflash, A.3
  • 59
    • 0038757823 scopus 로고    scopus 로고
    • Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2
    • Person RE, Li FQ, Duan Z, et al. Mutations in proto-oncogene GFI1 cause human neutropenia and target ELA2. Nat Genet. 2003; 34(3):308-312.
    • (2003) Nat Genet , vol.34 , Issue.3 , pp. 308-312
    • Person, R.E.1    Li, F.Q.2    Duan, Z.3
  • 60
    • 0036510161 scopus 로고    scopus 로고
    • Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1
    • Karsunky H, Zeng H, Schmidt T, et al. Inflammatory reactions and severe neutropenia in mice lacking the transcriptional repressor Gfi1. Nat Genet. 2002;30(3):295-300.
    • (2002) Nat Genet , vol.30 , Issue.3 , pp. 295-300
    • Karsunky, H.1    Zeng, H.2    Schmidt, T.3
  • 61
    • 0037244284 scopus 로고    scopus 로고
    • Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation
    • Hock H, Hamblen MJ, Rooke HM, et al. Intrinsic requirement for zinc finger transcription factor Gfi-1 in neutrophil differentiation. Immunity. 2003; 18(1):109-120.
    • (2003) Immunity , vol.18 , Issue.1 , pp. 109-120
    • Hock, H.1    Hamblen, M.J.2    Rooke, H.M.3
  • 62
    • 32944482517 scopus 로고    scopus 로고
    • The zinc finger protein Gfi1 acts upstream of TNF to attenuate endotoxin-mediated inflammatory responses in the lung
    • Jin J, Zeng H, Schmid KW, Toetsch M, Uhlig S, Möröy T. The zinc finger protein Gfi1 acts upstream of TNF to attenuate endotoxin-mediated inflammatory responses in the lung. Eur J Immunol. 2006;36(2):421-430.
    • (2006) Eur J Immunol , vol.36 , Issue.2 , pp. 421-430
    • Jin, J.1    Zeng, H.2    Schmid, K.W.3    Toetsch, M.4    Uhlig, S.5    Möröy, T.6
  • 63
    • 33745054357 scopus 로고    scopus 로고
    • Regulation of pulmonary Pseudomonas aeruginosa infection by the transcriptional repressor Gfi1
    • Grassmé H, Jin J, Wilker B, et al. Regulation of pulmonary Pseudomonas aeruginosa infection by the transcriptional repressor Gfi1. Cell Microbiol. 2006;8(7):1096-1105.
    • (2006) Cell Microbiol , vol.8 , Issue.7 , pp. 1096-1105
    • Grassmé, H.1    Jin, J.2    Wilker, B.3
  • 64
    • 80051505603 scopus 로고    scopus 로고
    • Hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network
    • Krumsiek J, Marr C, Schroeder T, Theis FJ. Hierarchical differentiation of myeloid progenitors is encoded in the transcription factor network. PLoS One. 2011;6(8):e22649.
    • (2011) PLoS One , vol.6 , Issue.8 , pp. e22649
    • Krumsiek, J.1    Marr, C.2    Schroeder, T.3    Theis, F.J.4
  • 65
    • 48749094942 scopus 로고    scopus 로고
    • E2A proteins promote development of lymphoid-primed multipotent progenitors
    • Dias S, Månsson R, Gurbuxani S, Sigvardsson M, Kee BL. E2A proteins promote development of lymphoid-primed multipotent progenitors. Immunity. 2008;29(2):217-227.
    • (2008) Immunity , vol.29 , Issue.2 , pp. 217-227
    • Dias, S.1    Månsson, R.2    Gurbuxani, S.3    Sigvardsson, M.4    Kee, B.L.5
  • 66
    • 17644443312 scopus 로고    scopus 로고
    • The transcriptional repressor Gfi1 affects development of early, uncommitted c-Kit1 T cell progenitors and CD4/CD8 lineage decision in the thymus
    • Yücel R, Karsunky H, Klein-Hitpass L, Möröy T. The transcriptional repressor Gfi1 affects development of early, uncommitted c-Kit1 T cell progenitors and CD4/CD8 lineage decision in the thymus. J Exp Med. 2003; 197(7):831-844.
    • (2003) J Exp Med , vol.197 , Issue.7 , pp. 831-844
    • Yücel, R.1    Karsunky, H.2    Klein-Hitpass, L.3    Möröy, T.4
  • 67
    • 0036467868 scopus 로고    scopus 로고
    • The zincfinger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages
    • Saleque S, Cameron S, Orkin SH. The zincfinger proto-oncogene Gfi-1b is essential for development of the erythroid and megakaryocytic lineages. Genes Dev. 2002; 16(3):301-306.
    • (2002) Genes Dev , vol.16 , Issue.3 , pp. 301-306
    • Saleque, S.1    Cameron, S.2    Orkin, S.H.3
  • 68
    • 14244258985 scopus 로고    scopus 로고
    • Direct transcriptional repression of the genes encoding the zinc-finger proteins Gfi1b and Gfi1 by Gfi1b
    • Vassen L, Fiolka K, Mahlmann S, Möröy T. Direct transcriptional repression of the genes encoding the zinc-finger proteins Gfi1b and Gfi1 by Gfi1b. Nucleic Acids Res. 2005;33(3): 987-998.
    • (2005) Nucleic Acids Res , vol.33 , Issue.3 , pp. 987-998
    • Vassen, L.1    Fiolka, K.2    Mahlmann, S.3    Möröy, T.4
  • 69
    • 0035756684 scopus 로고    scopus 로고
    • The end is just the beginning: Megakaryocyte apoptosis and platelet release
    • Li J, Kuter DJ. The end is just the beginning: megakaryocyte apoptosis and platelet release. Int J Hematol. 2001;74(4):365-374.
    • (2001) Int J Hematol , vol.74 , Issue.4 , pp. 365-374
    • Li, J.1    Kuter, D.J.2
  • 70
    • 0036729878 scopus 로고    scopus 로고
    • High-throughput retroviral tagging to identify components of specific signaling pathways in cancer [published corrections appears in Nat Genet 2002; 32(2):331 and Nat Genet. 2002 32(3):459]
    • Mikkers H, Allen J, Knipscheer P, et al. High-throughput retroviral tagging to identify components of specific signaling pathways in cancer [published corrections appears in Nat Genet. 2002;32(2):331 and Nat Genet. 2002; 32(3):459]. Nat Genet. 2002;32(1):153-159.
    • (2002) Nat Genet , vol.32 , Issue.1 , pp. 153-159
    • Mikkers, H.1    Allen, J.2    Knipscheer, P.3
  • 71
    • 77950356588 scopus 로고    scopus 로고
    • Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia
    • Sanda T, Li X, Gutierrez A, et al. Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia. Blood. 2010; 115(9):1735-1745.
    • (2010) Blood , vol.115 , Issue.9 , pp. 1735-1745
    • Sanda, T.1    Li, X.2    Gutierrez, A.3
  • 72
    • 1642317557 scopus 로고    scopus 로고
    • Gene expression profile of adult T-cell acute lymphocytic leukemia identifies distinct subsets of patients with different response to therapy and survival
    • Chiaretti S, Li X, Gentleman R, et al. Gene expression profile of adult T-cell acute lymphocytic leukemia identifies distinct subsets of patients with different response to therapy and survival. Blood. 2004;103(7): 2771-2778.
    • (2004) Blood , vol.103 , Issue.7 , pp. 2771-2778
    • Chiaretti, S.1    Li, X.2    Gentleman, R.3
  • 73
    • 84901743776 scopus 로고    scopus 로고
    • Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis
    • Huser CA, Gilroy KL, de Ridder J, et al. Insertional mutagenesis and deep profiling reveals gene hierarchies and a Myc/p53-dependent bottleneck in lymphomagenesis. PLoS Genet. 2014;10(2): e1004167.
    • (2014) PLoS Genet , vol.10 , Issue.2 , pp. e1004167
    • Huser, C.A.1    Gilroy, K.L.2    De Ridder, J.3
  • 74
    • 0036786901 scopus 로고    scopus 로고
    • The World Health Organization (WHO) classification of the myeloid neoplasms
    • Vardiman JW, Harris NL, Brunning RD. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood. 2002;100(7): 2292-2302.
    • (2002) Blood , vol.100 , Issue.7 , pp. 2292-2302
    • Vardiman, J.W.1    Harris, N.L.2    Brunning, R.D.3
  • 75
    • 0029798607 scopus 로고    scopus 로고
    • Revised classification of acute myeloid leukemia
    • Head DR. Revised classification of acute myeloid leukemia. Leukemia. 1996;10(11):1826-1831.
    • (1996) Leukemia , vol.10 , Issue.11 , pp. 1826-1831
    • Head, D.R.1
  • 76
    • 0031005627 scopus 로고    scopus 로고
    • Acute myeloid leukemia in the elderly: Assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study
    • Leith CP, Kopecky KJ, Godwin J, et al. Acute myeloid leukemia in the elderly: assessment of multidrug resistance (MDR1) and cytogenetics distinguishes biologic subgroups with remarkably distinct responses to standard chemotherapy. A Southwest Oncology Group study. Blood. 1997; 89(9):3323-3329.
    • (1997) Blood , vol.89 , Issue.9 , pp. 3323-3329
    • Leith, C.P.1    Kopecky, K.J.2    Godwin, J.3
  • 77
    • 77950582398 scopus 로고    scopus 로고
    • A variant allele of growth factor independence 1 (GFI1) is associated with acute myeloid leukemia
    • Khandanpour C, Thiede C, Valk PJ, et al. A variant allele of growth factor independence 1 (GFI1) is associated with acute myeloid leukemia. Blood. 2010;115(12):2462-2472.
    • (2010) Blood , vol.115 , Issue.12 , pp. 2462-2472
    • Khandanpour, C.1    Thiede, C.2    Valk, P.J.3
  • 78
    • 40249100094 scopus 로고    scopus 로고
    • Mutations in growth factor independent-1 associated with human neutropenia block murine granulopoiesis through colony stimulating factor-1
    • Zarebski A, Velu CS, Baktula AM, et al. Mutations in growth factor independent-1 associated with human neutropenia block murine granulopoiesis through colony stimulating factor-1. Immunity. 2008;28(3):370-380.
    • (2008) Immunity , vol.28 , Issue.3 , pp. 370-380
    • Zarebski, A.1    Velu, C.S.2    Baktula, A.M.3
  • 79
    • 77952976669 scopus 로고    scopus 로고
    • The transcription factor Gfi1 regulates G-CSF signaling and neutrophil development through the Ras activator RasGRP1
    • de la Luz Sierra M, Sakakibara S, Gasperini P, et al. The transcription factor Gfi1 regulates G-CSF signaling and neutrophil development through the Ras activator RasGRP1. Blood. 2010; 115(19):3970-3979.
    • (2010) Blood , vol.115 , Issue.19 , pp. 3970-3979
    • De La Luz Sierra, M.1    Sakakibara, S.2    Gasperini, P.3
  • 80
    • 33745508917 scopus 로고    scopus 로고
    • Severe congenital neutropenia
    • Welte K, Zeidler C, Dale DC. Severe congenital neutropenia. Semin Hematol. 2006;43(3): 189-195.
    • (2006) Semin Hematol , vol.43 , Issue.3 , pp. 189-195
    • Welte, K.1    Zeidler, C.2    Dale, D.C.3
  • 81
    • 70350435426 scopus 로고    scopus 로고
    • Prevalence of mutations in ELANE, GFI1, HAX1, SBDS, WAS and G6PC3 in patients with severe congenital neutropenia
    • Xia J, Bolyard AA, Rodger E, et al. Prevalence of mutations in ELANE, GFI1, HAX1, SBDS, WAS and G6PC3 in patients with severe congenital neutropenia. Br J Haematol. 2009;147(4): 535-542.
    • (2009) Br J Haematol , vol.147 , Issue.4 , pp. 535-542
    • Xia, J.1    Bolyard, A.A.2    Rodger, E.3
  • 82
    • 84922823799 scopus 로고    scopus 로고
    • Genetic analysis and clinical picture of severe congenital neutropenia in Israel
    • Lebel A, Yacobovich J, Krasnov T, et al. Genetic analysis and clinical picture of severe congenital neutropenia in Israel. Pediatr Blood Cancer. 2015; 62(1):103-108.
    • (2015) Pediatr Blood Cancer. , vol.62 , Issue.1 , pp. 103-108
    • Lebel, A.1    Yacobovich, J.2    Krasnov, T.3
  • 83
    • 84875492764 scopus 로고    scopus 로고
    • Different pattern of gene mutations in Iranian patients with severe congenital neutropenia (including 2 new mutations)
    • Alizadeh Z, Fazlollahi MR, Houshmand M, et al. Different pattern of gene mutations in Iranian patients with severe congenital neutropenia (including 2 new mutations). Iran J Allergy Asthma Immunol. 2013;12(1):86-92.
    • (2013) Iran J Allergy Asthma Immunol , vol.12 , Issue.1 , pp. 86-92
    • Alizadeh, Z.1    Fazlollahi, M.R.2    Houshmand, M.3
  • 84
    • 84872738388 scopus 로고    scopus 로고
    • Genetics and pathophysiology of severe congenital neutropenia syndromes unrelated to neutrophil elastase
    • vii
    • Boztug K, Klein C. Genetics and pathophysiology of severe congenital neutropenia syndromes unrelated to neutrophil elastase. Hematol Oncol Clin North Am. 2013;27(1):43-60, vii.
    • (2013) Hematol Oncol Clin North Am , vol.27 , Issue.1 , pp. 43-60
    • Boztug, K.1    Klein, C.2
  • 85
    • 79953045205 scopus 로고    scopus 로고
    • Genetic defects in severe congenital neutropenia: Emerging insights into life and death of human neutrophil granulocytes
    • Klein C. Genetic defects in severe congenital neutropenia: emerging insights into life and death of human neutrophil granulocytes. Annu Rev Immunol. 2011;29: 399-413.
    • (2011) Annu Rev Immunol , vol.29 , pp. 399-413
    • Klein, C.1
  • 86
    • 84887514998 scopus 로고    scopus 로고
    • GFI1B mutation causes a bleeding disorder with abnormal platelet function
    • Stevenson WS, Morel-Kopp MC, Chen Q, et al. GFI1B mutation causes a bleeding disorder with abnormal platelet function. J Thromb Haemost. 2013;11(11):2039-2047.
    • (2013) J Thromb Haemost , vol.11 , Issue.11 , pp. 2039-2047
    • Stevenson, W.S.1    Morel-Kopp, M.C.2    Chen, Q.3
  • 87
    • 84892566252 scopus 로고    scopus 로고
    • A dominant-negative GFI1B mutation in the gray platelet syndrome
    • Monteferrario D, Bolar NA, Marneth AE, et al. A dominant-negative GFI1B mutation in the gray platelet syndrome. N Engl J Med. 2014;370(3): 245-253.
    • (2014) N Engl J Med , vol.370 , Issue.3 , pp. 245-253
    • Monteferrario, D.1    Bolar, N.A.2    Marneth, A.E.3
  • 88
    • 84907916620 scopus 로고    scopus 로고
    • Transcriptional diversity during lineage commitment of human blood progenitors
    • BRIDGE Consortium
    • Chen L, Kostadima M, Martens JH, et al; BRIDGE Consortium. Transcriptional diversity during lineage commitment of human blood progenitors. Science. 2014;345(6204):1251033.
    • (2014) Science , vol.345 , Issue.6204 , pp. 1251033
    • Chen, L.1    Kostadima, M.2    Martens, J.H.3


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